| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Li, Jimok Ki. Distinct roles of neuronal and microglial CB2 cannabinoid receptors in the mouse hippocampus. Neuroscience. vol 363. 2018-06-08. PMID:28888955. |
distinct roles of neuronal and microglial cb2 cannabinoid receptors in the mouse hippocampus. |
2018-06-08 |
2023-08-13 |
mouse |
| Mingyue Zhang, Meng Chi, Huichao Zou, Songyu Tian, Zhaodi Zhang, Guonian Wan. Effects of coadministration of low dose cannabinoid type 2 receptor agonist and morphine on vanilloid receptor 1 expression in a rat model of cancer pain. Molecular medicine reports. vol 16. issue 5. 2018-06-04. PMID:28901432. |
our previous research has showed that nonanalgetic dose of a cannabinoid type 2 (cb2) receptor agonist reduced morphine tolerance in cancer pain. |
2018-06-04 |
2023-08-13 |
human |
| Juan Niu, Dujuan Huang, Rui Zhou, MingXia Yue, Tao Xu, Junna Yang, Li He, Hong Tian, XiaoHong Liu, Junwei Zen. Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y Journal of neuroinflammation. vol 14. issue 1. 2018-05-29. PMID:28899427. |
activation of dorsal horn cannabinoid cb2 receptor suppresses the expression of p2y more evidence suggests that dorsal spinal cord microglia is an important site contributing to cb2 receptor-mediated analgesia. |
2018-05-29 |
2023-08-13 |
Not clear |
| Foteini Delis, Alexia Polissidis, Nafsika Poulia, Zuzana Justinova, George G Nomikos, Steven R Goldberg, Katerina Antonio. Attenuation of Cocaine-Induced Conditioned Place Preference and Motor Activity via Cannabinoid CB2 Receptor Agonism and CB1 Receptor Antagonism in Rats. The international journal of neuropsychopharmacology. vol 20. issue 3. 2018-05-21. PMID:27994006. |
attenuation of cocaine-induced conditioned place preference and motor activity via cannabinoid cb2 receptor agonism and cb1 receptor antagonism in rats. |
2018-05-21 |
2023-08-13 |
rat |
| Bin-Xiao Su, Xin Chen, Jia Huo, Shu-Yun Guo, Rui Ma, Yan-Wu Li. The synthetic cannabinoid WIN55212-2 ameliorates traumatic spinal cord injury via inhibition of GAPDH/Siah1 in a CB2-receptor dependent manner. Brain research. vol 1671. 2018-05-17. PMID:28716633. |
the endocannabinoid system, including its receptors (cb1 and cb2), act as neuroprotective and immunomodulatory modulators in sci. |
2018-05-17 |
2023-08-13 |
Not clear |
| M Khodadadi, M Zendehdel, A Baghbanzadeh, V Babapou. Consequence of dopamine D2 receptor blockade on the hyperphagic effect induced by cannabinoid CB1 and CB2 receptors in layers. British poultry science. vol 58. issue 5. 2018-05-14. PMID:28728428. |
consequence of dopamine d2 receptor blockade on the hyperphagic effect induced by cannabinoid cb1 and cb2 receptors in layers. |
2018-05-14 |
2023-08-13 |
Not clear |
| Wen-Jing Qian, Ning Yin, Feng Gao, Yanying Miao, Qian Li, Fang Li, Xing-Huai Sun, Xiong-Li Yang, Zhongfeng Wan. Cannabinoid CB1 and CB2 receptors differentially modulate L- and T-type Ca Neuropharmacology. vol 124. 2018-05-09. PMID:28431968. |
cannabinoid cb1 and cb2 receptors differentially modulate l- and t-type ca endocannabinoid signaling system is involved in regulating multiple neuronal functions in the central nervous system by activating g-protein coupled cannabinoid cb1 and cb2 receptors (cb1rs and cb2rs). |
2018-05-09 |
2023-08-13 |
Not clear |
| Camilla P Dias-Rocha, Mariana M Almeida, Erika M Santana, Julia C B Costa, Juliana G Franco, Carmen C Pazos-Moura, Isis H Trevenzol. Maternal high-fat diet induces sex-specific endocannabinoid system changes in newborn rats and programs adiposity, energy expenditure and food preference in adulthood. The Journal of nutritional biochemistry. vol 51. 2018-05-09. PMID:29102876. |
the ecs consists mainly of endogenous ligands, cannabinoid receptors (cb1 and cb2), and the enzymes fatty acid anandamide hydrolase (faah) and monoacylglycerol lipase (magl). |
2018-05-09 |
2023-08-13 |
rat |
| Yu Liu, Samuel S McAfee, Natalie M Guley, Nobel Del Mar, Wei Bu, Scott A Heldt, Marcia G Honig, Bob M Moore, Anton Reiner, Detlef H Hec. Abnormalities in Dynamic Brain Activity Caused by Mild Traumatic Brain Injury Are Partially Rescued by the Cannabinoid Type-2 Receptor Inverse Agonist SMM-189. eNeuro. vol 4. issue 4. 2018-05-03. PMID:28828401. |
treatment with the cannabinoid type-2 (cb2) receptor inverse agonist smm-189 has been shown to mitigate functional deficits and neuronal injury after mtbi in mice. |
2018-05-03 |
2023-08-13 |
mouse |
| Paula Morales, Dow P Hurst, Patricia H Reggi. Methods for the Development of In Silico GPCR Models. Methods in enzymology. vol 593. 2018-04-26. PMID:28750813. |
the reggio group has constructed computer models of the inactive and g-protein-activated states of the cannabinoid cb1 and cb2 receptors, as well as, several orphan receptors that recognize a subset of cannabinoid compounds, including gpr55 and gpr18. |
2018-04-26 |
2023-08-13 |
Not clear |
| Hai-Jing Sun, Yan Lu, Hao-Wei Wang, Hao Zhang, Shuang-Ran Wang, Wen-Yun Xu, Hai-Long Fu, Xue-Ya Yao, Feng Yang, Hong-Bin Yua. Activation of Endocannabinoid Receptor 2 as a Mechanism of Propofol Pretreatment-Induced Cardioprotection against Ischemia-Reperfusion Injury in Rats. Oxidative medicine and cellular longevity. vol 2017. 2018-04-23. PMID:28814985. |
we concluded that enhancing endogenous endocannabinoid release and subsequent activation of cb2 receptor signaling represent a major mechanism whereby propofol conditioning confers antioxidative and cardioprotective effects against myocardial i/r injury. |
2018-04-23 |
2023-08-13 |
rat |
| Michael W Calik, David W Carle. Effects of Cannabinoid Agonists and Antagonists on Sleep and Breathing in Sprague-Dawley Rats. Sleep. vol 40. issue 9. 2018-04-23. PMID:28934522. |
in anesthetized rats, dronabinol attenuates reflex apnea via activation of cannabinoid (cb) receptors located on vagal afferents; an effect blocked by cannabinoid type 1 (cb1) and/or type 2 (cb2) receptor antagonists. |
2018-04-23 |
2023-08-13 |
rat |
| Morag Rose Hunter, Natasha Lillia Grimsey, Michelle Glas. Sulfation of the FLAG epitope is affected by co-expression of G protein-coupled receptors in a mammalian cell model. Scientific reports. vol 6. 2018-04-16. PMID:27273047. |
here, we describe the observation that co-expression of either cannabinoid cb1 or cb2 receptors in hek293 decreases the sulfation of a flag epitope appended at the n-terminus of the dopamine d2 receptor. |
2018-04-16 |
2023-08-13 |
Not clear |
| Eric Murillo-Rodriguez, Jose Carlos Pastrana-Trejo, Mireille Salas-Crisóstomo, Miriel de-la-Cru. The Endocannabinoid System Modulating Levels of Consciousness, Emotions and Likely Dream Contents. CNS & neurological disorders drug targets. vol 16. issue 4. 2018-04-16. PMID:28240187. |
the cannabinoid receptors have been described in rat, human and mouse brains and they have been named the cb1 and cb2 cannabinoid receptors. |
2018-04-16 |
2023-08-13 |
mouse |
| Helene Francois, Lola Lecr. The Role of Cannabinoid Receptors in Renal Diseases. Current medicinal chemistry. vol 25. issue 7. 2018-04-03. PMID:28901271. |
the cannabinoid system and more specifically the cannabinoid receptors 1 (cb1) and 2 (cb2) may represent a new therapeutic target in ckd. |
2018-04-03 |
2023-08-13 |
Not clear |
| Anna Lisa Brigida, Stephen Schultz, Mariana Cascone, Nicola Antonucci, Dario Siniscalc. Endocannabinod Signal Dysregulation in Autism Spectrum Disorders: A Correlation Link between Inflammatory State and Neuro-Immune Alterations. International journal of molecular sciences. vol 18. issue 7. 2018-03-30. PMID:28671614. |
the ec system is a complex network of lipid signaling pathways comprised of arachidonic acid-derived compounds (anandamide, aea) and 2-arachidonoyl glycerol (2-ag), their g-protein-coupled receptors (cannabinoid receptors cb1 and cb2) and the associated enzymes. |
2018-03-30 |
2023-08-13 |
Not clear |
| Esther Martínez-Martínez, Asunción Martín-Ruiz, Paloma Martín, Virginia Calvo, Mariano Provencio, José M Garcí. CB2 cannabinoid receptor activation promotes colon cancer progression via AKT/GSK3β signaling pathway. Oncotarget. vol 7. issue 42. 2018-03-22. PMID:27634891. |
taken together, our data show that cb2 activation with sub-micromolar doses of agonists, which could be more similar to endogenous levels of cannabinoids, promote colon cancer progression, implicating that cb2 could have a pro-tumorigenic endogenous role in colon cancer. |
2018-03-22 |
2023-08-13 |
Not clear |
| Jessica Freundt-Revilla, Franciska Heinrich, Alexander Zoerner, Felix Gesell, Martin Beyerbach, Merav Shamir, Anna Oevermann, Wolfgang Baumgärtner, Andrea Tipol. The endocannabinoid system in canine Steroid-Responsive Meningitis-Arteritis and Intraspinal Spirocercosis. PloS one. vol 13. issue 2. 2018-03-09. PMID:29408878. |
activation of cannabinoid type 2 receptors (cb2) is known to diminish the release of pro-inflammatory factors and enhance the secretion of anti-inflammatory cytokines. |
2018-03-09 |
2023-08-13 |
dog |
| Jessica Freundt-Revilla, Franciska Heinrich, Alexander Zoerner, Felix Gesell, Martin Beyerbach, Merav Shamir, Anna Oevermann, Wolfgang Baumgärtner, Andrea Tipol. The endocannabinoid system in canine Steroid-Responsive Meningitis-Arteritis and Intraspinal Spirocercosis. PloS one. vol 13. issue 2. 2018-03-09. PMID:29408878. |
furthermore, the endocannabinoid 2-arachidonoyl glycerol (2-ag) has been proved to induce the migration of eosinophils in a cb2 receptor-dependent manner in peripheral blood and activate neutrophils independent of cb activation in humans. |
2018-03-09 |
2023-08-13 |
dog |
| M E Ferrini, S Hong, A Stierle, D Stierle, N Stella, K Roberts, Z Jaffa. CB2 receptors regulate natural killer cells that limit allergic airway inflammation in a murine model of asthma. Allergy. vol 72. issue 6. 2018-03-07. PMID:27992060. |
endogenously generated cannabinoids acting via cb2 receptors play important roles in both homeostatic and inflammatory processes. |
2018-03-07 |
2023-08-13 |
Not clear |