Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Simran Maggo, John C Ashto. Effect of Cannabinoid Receptor Agonists on Isolated Rat Atria. Journal of cardiovascular pharmacology. vol 72. issue 4. 2019-06-18. PMID:30080756. |
our results indicate that cannabinoid cardiotoxicity may partially involve cb1 receptors in the myocardium, and that cb2 receptor agonists are unlikely to have significant effects on the heart. |
2019-06-18 |
2023-08-13 |
rat |
Ai-Ling Li, Xiaoyan Lin, Amey S Dhopeshwarkar, Ana Carla Thomaz, Lawrence M Carey, Yingpeng Liu, Spyros P Nikas, Alexandros Makriyannis, Ken Mackie, Andrea G Hohman. Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal. Molecular pharmacology. vol 95. issue 2. 2019-06-14. PMID:30504240. |
cannabinoid cb2 agonist am1710 differentially suppresses distinct pathological pain states and attenuates morphine tolerance and withdrawal. |
2019-06-14 |
2023-08-13 |
mouse |
Rodolfo Sánchez-Zavaleta, Hernán Cortés, José Arturo Avalos-Fuentes, Ubaldo García, José Segovia Vila, David Erlij, Benjamín Florá. Presynaptic cannabinoid CB2 receptors modulate [ Synapse (New York, N.Y.). vol 72. issue 11. 2019-06-10. PMID:30022523. |
presynaptic cannabinoid cb2 receptors modulate [ recent studies suggested the expression of cb2 receptors in neurons of the cns, however, most of these studies have only explored one aspect of the receptors, i.e., expression of protein, messenger rna, or functional response, and more complete studies appear to be needed to establish adequately their role in the neuronal function. |
2019-06-10 |
2023-08-13 |
Not clear |
Xue Shen, Hua Duan, Sha Wang, Lu Gan, Qian Xu, Jin-Jiao L. Decreased Expression of Cannabinoid Receptors in the Eutopic and Ectopic Endometrium of Patients with Adenomyosis. BioMed research international. vol 2019. 2019-06-10. PMID:30800671. |
our research aims to analyze the expression patterns of the typical cannabinoid receptors (cb1 and cb2), the main constituents of the endocannabinoid system, in endometrial samples derived from patients diagnosed as adenomyosis or not. |
2019-06-10 |
2023-08-13 |
Not clear |
Irena Kasacka, Żaneta Piotrowska, Anna Filipek, Wojciech Lebkowsk. Comparative evaluation of cannabinoid receptors, apelin and S100A6 protein in the heart of women of different age groups. BMC cardiovascular disorders. vol 18. issue 1. 2019-05-28. PMID:30286717. |
the aim of the study was to compare and evaluate the distribution of cannabinoid receptors (cb1 and cb2), apelin and s100a6 protein in the heart of healthy women in different age groups. |
2019-05-28 |
2023-08-13 |
Not clear |
Ana Gabriela Silva, Caio Fabio Baeta Lopes, Clóvis Gomes Carvalho Júnior, Ralph Gruppi Thomé, Hélio Batista Dos Santos, Rui Reis, Rosy Iara Maciel de Azambuja Ribeir. WIN55,212-2 induces caspase-independent apoptosis on human glioblastoma cells by regulating HSP70, p53 and Cathepsin D. Toxicology in vitro : an international journal published in association with BIBRA. vol 57. 2019-05-23. PMID:30776504. |
in this sense, cannabinoids highlight as a promising tool, because this tumor overexpresses cb1 and/or cb2 receptors and being, therefore, can be susceptible to cannabinoids treatment. |
2019-05-23 |
2023-08-13 |
human |
Jiliang Zhang, Shaojuan Zhang, Yang Liu, Meng Su, Xiaoxi Ling, Funan Liu, Yinghui Ge, Mingfeng Ba. Combined CB2 receptor agonist and photodynamic therapy synergistically inhibit tumor growth in triple negative breast cancer. Photodiagnosis and photodynamic therapy. vol 24. 2019-05-17. PMID:30240926. |
this combinatory therapy targets two proteins upregulated in tnbc: the cannabinoid cb2 receptor (cb |
2019-05-17 |
2023-08-13 |
Not clear |
Ana Canseco-Alba, Norman Schanz, Branden Sanabria, Juan Zhao, Zhicheng Lin, Qing-Rong Liu, Emmanuel S Onaiv. Behavioral effects of psychostimulants in mutant mice with cell-type specific deletion of CB2 cannabinoid receptors in dopamine neurons. Behavioural brain research. vol 360. 2019-05-02. PMID:30508607. |
behavioral effects of psychostimulants in mutant mice with cell-type specific deletion of cb2 cannabinoid receptors in dopamine neurons. |
2019-05-02 |
2023-08-13 |
mouse |
Dina A Ezzat, Amira A Hammam, Waleed M El-Malah, Rasha A Khattab, Eman M Mangou. Role of Cannabinoid CB2 Receptor Gene (CNR2) Polymorphism in Children with Immune Thrombocytopenic Purpura in Beni-Suef Governorate in Egypt. The Egyptian journal of immunology. vol 24. issue 1. 2019-04-25. PMID:29120578. |
role of cannabinoid cb2 receptor gene (cnr2) polymorphism in children with immune thrombocytopenic purpura in beni-suef governorate in egypt. |
2019-04-25 |
2023-08-13 |
Not clear |
Dina A Ezzat, Amira A Hammam, Waleed M El-Malah, Rasha A Khattab, Eman M Mangou. Role of Cannabinoid CB2 Receptor Gene (CNR2) Polymorphism in Children with Immune Thrombocytopenic Purpura in Beni-Suef Governorate in Egypt. The Egyptian journal of immunology. vol 24. issue 1. 2019-04-25. PMID:29120578. |
the cb2 is encoded by the cannabinoid cb receptor gene (cnr2) gene. |
2019-04-25 |
2023-08-13 |
Not clear |
Vanessa Petrucci, Andrea Chicca, Sandra Glasmacher, Janos Paloczi, Zongxian Cao, Pal Pacher, Jürg Gertsc. Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage. Scientific reports. vol 7. issue 1. 2019-04-16. PMID:28842619. |
however, it remains unknown whether pepcans occur in the periphery and interact with peripheral cb2 cannabinoid receptors. |
2019-04-16 |
2023-08-13 |
Not clear |
Magdalena Borowska, Agata Czarnywojtek, Nadia Sawicka-Gutaj, Kosma Woliński, Maria Teresa Płazińska, Przemysław Mikołajczak, Marek Ruchał. The effects of cannabinoids on the endocrine system. Endokrynologia Polska. vol 69. issue 6. 2019-04-16. PMID:30618031. |
these compounds exert their effects via interaction with the cannabinoid receptors cb1 and cb2. |
2019-04-16 |
2023-08-13 |
Not clear |
Magdalena Borowska, Agata Czarnywojtek, Nadia Sawicka-Gutaj, Kosma Woliński, Maria Teresa Płazińska, Przemysław Mikołajczak, Marek Ruchał. The effects of cannabinoids on the endocrine system. Endokrynologia Polska. vol 69. issue 6. 2019-04-16. PMID:30618031. |
type 2 cannabinoid receptors (cb2) are positioned in the peripheral nervous system (peripheral nerve endings) and on the surface of the immune system cells. |
2019-04-16 |
2023-08-13 |
Not clear |
Roberto Cili. Molecular Imaging of the Cannabinoid System in Idiopathic Parkinson's Disease. International review of neurobiology. vol 141. 2019-04-11. PMID:30314601. |
the endocannabinoid system has been additionally implicated in the regulation of neuroinflammation and neuroprotection through the activation of cb2 receptors, suggesting a potential target for disease modifying therapies in parkinson's disease. |
2019-04-11 |
2023-08-13 |
Not clear |
Giorgia Galiazzo, Fiorella Giancola, Agnese Stanzani, Federico Fracassi, Chiara Bernardini, Monica Forni, Marco Pietra, Roberto Chiocchett. Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract. Histochemistry and cell biology. vol 150. issue 2. 2019-04-08. PMID:29882158. |
localization of cannabinoid receptors cb1, cb2, gpr55, and pparα in the canine gastrointestinal tract. |
2019-04-08 |
2023-08-13 |
dog |
Giorgia Galiazzo, Fiorella Giancola, Agnese Stanzani, Federico Fracassi, Chiara Bernardini, Monica Forni, Marco Pietra, Roberto Chiocchett. Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract. Histochemistry and cell biology. vol 150. issue 2. 2019-04-08. PMID:29882158. |
the present ex vivo study aimed to investigate immunohistochemically the distribution of cannabinoid receptors cb1, cb2, g protein-coupled receptor 55 (gpr55), and peroxisome proliferation activation receptor alpha (pparα) in the canine gastrointestinal tract. |
2019-04-08 |
2023-08-13 |
dog |
S Vijayakumar, P Manogar, S Prabhu, M Pugazhenthi, P K Praseeth. A pharmacoinformatic approach on Cannabinoid receptor 2 (CB2) and different small molecules: Homology modelling, molecular docking, MD simulations, drug designing and ADME analysis. Computational biology and chemistry. vol 78. 2019-04-08. PMID:30500557. |
therefore, the usneoidone has incorporated to md simulation with cannabinoid receptors 2 (cb2). |
2019-04-08 |
2023-08-13 |
human |
Luzia S Sampaio, Fabio A Iannotti, Luciana Veneziani, Rosa T Borelli-Tôrres, Fabrizia De Maio, Fabiana Piscitelli, Ricardo A M Reis, Vincenzo Di Marzo, Marcelo Einicker-Lama. Experimental ischemia/reperfusion model impairs endocannabinoid signaling and Na Biochemical pharmacology. vol 154. 2019-04-03. PMID:29890144. |
experimental ischemia/reperfusion model impairs endocannabinoid signaling and na llc-pk1 cells, an immortalized epithelial cell line derived from pig renal proximal tubules, express all the major players of the endocannabinoid system (ecs) such as cb1, cb2 and trpv1 receptors, as well as the main enzymes involved in the biosynthesis and degradation of the major endocannabinoids named 2-arachidonoylglycerol, 2-ag and anandamide, aea. |
2019-04-03 |
2023-08-13 |
rat |
Camila Marchioni, Israel Donizeti de Souza, Vinicius Ricardo Acquaro, José Alexandre de Souza Crippa, Vitor Tumas, Maria Eugênia Costa Queiro. Recent advances in LC-MS/MS methods to determine endocannabinoids in biological samples: Application in neurodegenerative diseases. Analytica chimica acta. vol 1044. 2019-04-03. PMID:30442393. |
endocannabinoids (ecs) are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors [cannabinoid receptor 1 (cb1) and cannabinoid receptor 2 (cb2)]. |
2019-04-03 |
2023-08-13 |
Not clear |
Żaneta Piotrowska, Michał Niezgoda, Wojciech Łebkowski, Anna Filipek, Natalia Domian, Irena Kasack. Sex differences in distribution of cannabinoid receptors (CB1 and CB2), S100A6 and CacyBP/SIP in human ageing hearts. Biology of sex differences. vol 9. issue 1. 2019-03-20. PMID:30482253. |
sex differences in distribution of cannabinoid receptors (cb1 and cb2), s100a6 and cacybp/sip in human ageing hearts. |
2019-03-20 |
2023-08-13 |
human |