| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pratima Dibba, Andrew A Li, George Cholankeril, Umair Iqbal, Chiranjeevi Gadiparthi, Muhammad Ali Khan, Donghee Kim, Aijaz Ahme. The Role of Cannabinoids in the Setting of Cirrhosis. Medicines (Basel, Switzerland). vol 5. issue 2. 2020-09-30. PMID:29890719. |
the endocannabinoid system comprises cannabinoid receptors 1 (cb1) and cannabinoid receptor 2 (cb2) and their ligands, endocannabinoids and exocannabinoids. |
2020-09-30 |
2023-08-13 |
mouse |
| Alyssa S Laun, Sarah H Shrader, Zhao-Hui Son. Novel inverse agonists for the orphan G protein-coupled receptor 6. Heliyon. vol 4. issue 11. 2020-09-30. PMID:30480157. |
gpr6, along with closely related orphan receptors gpr3 and gpr12, are phylogenetically related to cb1 and cb2 cannabinoid receptors. |
2020-09-30 |
2023-08-13 |
Not clear |
| Masahiro Kita, Yasuhisa Ano, Asuka Inoue, Junken Aok. Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells. Scientific reports. vol 9. issue 1. 2020-09-30. PMID:30816271. |
oleamide is an endocannabinoid and displays anti-inflammatory activity via the cannabinoid-2 (cb2) receptor; however, the mechanism underlying this anti-inflammatory activity has not been fully elucidated. |
2020-09-30 |
2023-08-13 |
human |
| Hesham M Mahmoud, Mona Osman, Osama Elshabrawy, Heba M I Abdallah, Ahmed Khairalla. AM-1241 CB2 Receptor Agonist Attenuates Inflammation, Apoptosis and Stimulate Progenitor Cells in Bile Duct Ligated Rats. Open access Macedonian journal of medical sciences. vol 7. issue 6. 2020-09-30. PMID:30976335. |
cannabinoid cb2 receptor activation has been reported to attenuate liver fibrosis in ccl4 exposed mice and also plays a potential role in liver regeneration in a mouse model of i/r and protection against alcohol-induced liver injury. |
2020-09-30 |
2023-08-13 |
mouse |
| Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Oleg Yurevich, Jonathan Francois, Denis Yusupov, Angelina Zhyvotovska, Louis Salciccioli, Sudhanva Hegde, Samy I McFarlan. Atrioventricular Nodal Reentrant Tachycardia Triggered by Marijuana Use: A Case Report and Review of the Literature. American journal of medical case reports. vol 7. issue 9. 2020-09-30. PMID:31396556. |
delta-9-tetrahydrocannabinol (thc) is the psychotropic component of marijuana, acting via cb1 and cb2 g-protein coupled cannabinoid receptors. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ahmed Sharaf, Leonore Mensching, Christina Keller, Sebastian Rading, Marina Scheffold, Lysann Palkowitsch, Nevena Djogo, Meriem Rezgaoui, Hans A Kestler, Barbara Moepps, Antonio Virgilio Failla, Meliha Karsa. Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome. Frontiers in molecular neuroscience. vol 12. 2020-09-30. PMID:31616248. |
the endocannabinoid system (ecs) consists particularly of cannabinoid receptors 1 and 2 (cb1 and cb2), their endogenous ligands, and enzymes that synthesize and degrade their ligands. |
2020-09-30 |
2023-08-13 |
Not clear |
| Igor Grant, B Rael Cah. Cannabis and endocannabinoid modulators: Therapeutic promises and challenges. Clinical neuroscience research. vol 5. issue 2-4. 2020-09-29. PMID:18806886. |
this paper reviews current understanding of cb1, cb2, and other possible cannabinoid receptors, their arachidonic acid derived ligands (e.g. |
2020-09-29 |
2023-08-12 |
Not clear |
| Ali Parlar, Seyfullah Oktay Arslan, Muhammed Fatih Doğan, Saliha Ayşenur Çam, Alper Yalçin, Ebru Elibol, Mehmet Kaya Özer, Fatih Üçkardeş, Halil Kar. The exogenous administration of CB2 specific agonist, GW405833, inhibits inflammation by reducing cytokine production and oxidative stress. Experimental and therapeutic medicine. vol 16. issue 6. 2020-09-29. PMID:30542446. |
the present study aimed to investigate the role of cannabinoid 2 (cb2) receptors in a rat model of acute inflammation. |
2020-09-29 |
2023-08-13 |
rat |
| Paula Morales, Nadine Jagerovi. Antitumor Cannabinoid Chemotypes: Structural Insights. Frontiers in pharmacology. vol 10. 2020-09-29. PMID:31214034. |
cannabinoids of endogenous, phytogenic, and synthetic nature have been shown to impact the proliferation of cancer through the modulation of different proteins involved in the endocannabinoid system such as the g protein-coupled receptors cb1, cb2, and grp55, the ionotropic receptor trpv1, or the fatty acid amide hydrolase (faah). |
2020-09-29 |
2023-08-13 |
Not clear |
| Luka Dobovišek, Fran Krstanović, Simona Borštnar, Nataša Debelja. Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment. Cancers. vol 12. issue 3. 2020-09-28. PMID:32106399. |
endogenous cannabinoids together with cannabinoid receptor 1 and 2 (cb1, cb2) constitute the basis of the endocannabinoid system. |
2020-09-28 |
2023-08-13 |
Not clear |
| Abhilash Perisetti, Afrina Hossain Rimu, Salman Ali Khan, Pardeep Bansal, Hemant Goya. Role of cannabis in inflammatory bowel diseases. Annals of gastroenterology. vol 33. issue 2. 2020-09-28. PMID:32127734. |
endogenous circulating cannabinoids, or endocannabinoids, such as anandamide and 2-arachidonoyl-glycerol, their metabolizing enzymes (fatty acid amide hydrolase and monoacylglycerol lipase) and 2 g-protein coupled cannabinoid receptors, cb1 and cb2, together represent the endocannabinoid system and are present throughout the human body. |
2020-09-28 |
2023-08-13 |
human |
| Eugene L Scharf, Jon O Ebber. Endocannabinoids and Stroke Prevention: Review of Clinical Studies. Cannabis and cannabinoid research. vol 5. issue 1. 2020-09-28. PMID:32322672. |
cannabinoid receptors are reported on macrophages within atherosclerotic plaques and suggest a role for immunomodulation as a therapeutic for atherosclerosis through both peripheral immune cell cb1 antagonism and/or cb2 agonist. |
2020-09-28 |
2023-08-13 |
human |
| Pramod Theetha Kariyanna, Leanna R Smith, Karishma Patwa, Moro O Salifu, Isabel M McFarlan. Marijuana and Microcirculation: A Review. American journal of medical case reports. vol 8. issue 9. 2020-09-28. PMID:32775630. |
thc exerts effects through the cannabinoid receptors, cb1 and cb2. |
2020-09-28 |
2023-08-13 |
Not clear |
| Ali Parlar, Seyfullah Oktay Arsla. CB2 Agonist (AM1241) Improving Effect on Ovalbumin-Induced Asthma in Rats. Iranian journal of pharmaceutical research : IJPR. vol 19. issue 1. 2020-09-28. PMID:32922464. |
in order to better understand the role of the cannabinoid (cb) 2 receptor in the ovalbumin (ova)-induced asthma model, a combination of both selective cb2 agonist (am1241) and antagonist (am630) was used to improve inflammatory hypersensitivity and edema in rats. |
2020-09-28 |
2023-08-13 |
human |
| Puspanjali Bhatta, Asmita Dhukhwa, Kelly Sheehan, Raheem F H Al Aameri, Vikrant Borse, Sumana Ghosh, Sandeep Sheth, Chaitanya Mamillapalli, Leonard Rybak, Vickram Ramkumar, Debashree Mukherje. Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea. Scientific reports. vol 9. issue 1. 2020-09-24. PMID:30858408. |
capsaicin protects against cisplatin ototoxicity by changing the stat3/stat1 ratio and activating cannabinoid (cb2) receptors in the cochlea. |
2020-09-24 |
2023-08-13 |
rat |
| Manjunath Lamani, Michael S Malamas, Shrouq I Farah, Vidyanand G Shukla, Michael F Almeida, Catherine M Weerts, Joseph Anderson, JodiAnne T Wood, Karen L G Farizatto, Ben A Bahr, Alexandros Makriyanni. Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology. Bioorganic & medicinal chemistry. vol 27. issue 23. 2020-09-24. PMID:31629610. |
the new inhibitors showed potent nanomolar inhibitory activity against human recombinant and purified rat faah, were selective (>1000-fold) against serine hydrolases mgl and abhd6 and lacked any affinity for the cannabinoid receptors cb1 and cb2. |
2020-09-24 |
2023-08-13 |
human |
| Pedro Sánchez-Aparicio, Benjamín Florán, Desiderio Rodríguez Velázquez, José Antonio Ibancovichi, Jorge Antonio Varela Guerrero, Sergio Recilla. Cannabinoids CB2 Receptors, One New Promising Drug Target for Chronic and Degenerative Pain Conditions in Equine Veterinary Patients. Journal of equine veterinary science. vol 85. 2020-09-18. PMID:31952645. |
cannabinoids cb2 receptors, one new promising drug target for chronic and degenerative pain conditions in equine veterinary patients. |
2020-09-18 |
2023-08-13 |
Not clear |
| Pedro Sánchez-Aparicio, Benjamín Florán, Desiderio Rodríguez Velázquez, José Antonio Ibancovichi, Jorge Antonio Varela Guerrero, Sergio Recilla. Cannabinoids CB2 Receptors, One New Promising Drug Target for Chronic and Degenerative Pain Conditions in Equine Veterinary Patients. Journal of equine veterinary science. vol 85. 2020-09-18. PMID:31952645. |
nowadays, the use of new alternatives for this pathology attention is demanded; in that sense, cannabinoid cb2 agonists may represent a novel alternative. |
2020-09-18 |
2023-08-13 |
Not clear |
| Pedro Sánchez-Aparicio, Benjamín Florán, Desiderio Rodríguez Velázquez, José Antonio Ibancovichi, Jorge Antonio Varela Guerrero, Sergio Recilla. Cannabinoids CB2 Receptors, One New Promising Drug Target for Chronic and Degenerative Pain Conditions in Equine Veterinary Patients. Journal of equine veterinary science. vol 85. 2020-09-18. PMID:31952645. |
the aim of this study was to contribute to understand the pharmacology of cannabinoid cb2 receptors and its potential utilization on equine veterinary patients with a chronic degenerative painful condition. |
2020-09-18 |
2023-08-13 |
Not clear |
| Ishnoor Kaur, Tapan Behl, Simona Bungau, Gokhan Zengin, Arun Kumar, Mohamed A El-Esawi, Gaurav Khullar, Thangavel Venkatachalam, Sandeep Aror. The endocannabinoid signaling pathway as an emerging target in pharmacotherapy, earmarking mitigation of destructive events in rheumatoid arthritis. Life sciences. vol 257. 2020-09-17. PMID:32698072. |
the action of endocannabinoid system in immune system regulation, via primary cb2 activation, followed by inhibition of production of pro-inflammatory cytokines, auto-antibodies and mmps, flss proliferation and t-cell mediated immune response, are elaborated as potential therapeutic regimes in rheumatoid arthritis. |
2020-09-17 |
2023-08-13 |
Not clear |