| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elisa Nent, Chihiro Nozaki, Anne-Caroline Schmöle, David Otte, Andreas Zimme. CB2 receptor deletion on myeloid cells enhanced mechanical allodynia in a mouse model of neuropathic pain. Scientific reports. vol 9. issue 1. 2020-10-14. PMID:31097758. |
mechanisms leading to mirror-image pain are not completely understood, but cannabinoid cb2 receptors have been implicated. |
2020-10-14 |
2023-08-13 |
mouse |
| Alireza Tahamtan, Shahrzad Rezaiy, Saeed Samadizadeh, Abdolvahab Moradi, Alijan Tabarraei, Naeme Javid, Morteza Oladnabi, Mohammad Hosein Naeim. Cannabinoid CB2 Receptor Functional Variation (Q63R) Is Associated with Multiple Sclerosis in Iranian Subjects. Journal of molecular neuroscience : MN. vol 70. issue 1. 2020-10-08. PMID:31407233. |
cannabinoid cb2 receptor functional variation (q63r) is associated with multiple sclerosis in iranian subjects. |
2020-10-08 |
2023-08-13 |
human |
| Alireza Tahamtan, Shahrzad Rezaiy, Saeed Samadizadeh, Abdolvahab Moradi, Alijan Tabarraei, Naeme Javid, Morteza Oladnabi, Mohammad Hosein Naeim. Cannabinoid CB2 Receptor Functional Variation (Q63R) Is Associated with Multiple Sclerosis in Iranian Subjects. Journal of molecular neuroscience : MN. vol 70. issue 1. 2020-10-08. PMID:31407233. |
variations in the cannabinoid cb2 receptor gene (cnr2) could affect intracellular signaling and reduce system function, which has been associated with an unbalanced immune response and increased risk of a variety of autoimmune inflammatory disorders. |
2020-10-08 |
2023-08-13 |
human |
| Ilaria Ceccarelli, Paolo Fiorenzani, Federica Pessina, Jessica Pinassi, Margherita Aglianò, Vincenzo Miragliotta, Anna Maria Alois. The CB2 Agonist β-Caryophyllene in Male and Female Rats Exposed to a Model of Persistent Inflammatory Pain. Frontiers in neuroscience. vol 14. 2020-10-06. PMID:33013287. |
cannabinoids help in pain treatment through their action on cb1 and cb2 receptors. |
2020-10-06 |
2023-08-13 |
rat |
| Muneer Ahamed, Daisy van Veghel, Christoph Ullmer, Koen Van Laere, Alfons Verbruggen, Guy M Borman. Synthesis, Biodistribution and Frontiers in neuroscience. vol 10. 2020-10-01. PMID:27713686. |
synthesis, biodistribution and the type 2 cannabinoid receptor (cb2) is a member of the endocannabinoid system and is known for its important role in (neuro)inflammation. |
2020-10-01 |
2023-08-13 |
Not clear |
| Maria Notarnicola, Valeria Tutino, Angela Tafaro, Giusy Bianco, Emilia Guglielmi, Maria Gabriella Carus. Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of Apc Nutrition and healthy aging. vol 4. issue 1. 2020-10-01. PMID:28035344. |
dietary olive oil induces cannabinoid cb2 receptor expression in adipose tissue of apc |
2020-10-01 |
2023-08-13 |
Not clear |
| Marc-Alain Babi, Christopher P Robinson, Carolina B Macie. A spicy status: Synthetic cannabinoid (spice) use and new-onset refractory status epilepticus-A case report and review of the literature. SAGE open medical case reports. vol 5. 2020-10-01. PMID:29238581. |
synthetic cannabinoids refer to a wide variety of chemicals engineered to bind cannabinoid receptors (cb1 and cb2) and mimic the effects of delta-9-tetrahydrocanabinol. |
2020-10-01 |
2023-08-13 |
Not clear |
| Fatemeh Mohammadpour, Seyed Nasser Ostad, Shima Aliebrahimi, Zahra Dama. Anti-invasion Effects of Cannabinoids Agonist and Antagonist on Human Breast Cancer Stem Cells. Iranian journal of pharmaceutical research : IJPR. vol 16. issue 4. 2020-10-01. PMID:29552056. |
recent studies have reported different effects of cannabinoids on cancer cells via cb1 and cb2 cannabinoid receptors. |
2020-10-01 |
2023-08-13 |
human |
| Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Sudhanva Hegde, Jonathan D Marmur, Perry Wengrofsky, Mena Yacoub, Michael Post, Samy I McFarlan. Marijuana Induced Type I Brugada Pattern: A Case Report. American journal of medical case reports. vol 6. issue 7. 2020-10-01. PMID:30294671. |
marijuana acts on cannabinoid receptors cb1, cb2 and another distinct endothelial receptor. |
2020-10-01 |
2023-08-13 |
Not clear |
| Chanté Muller, Paula Morales, Patricia H Reggi. Cannabinoid Ligands Targeting TRP Channels. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30697147. |
although cb1 and cb2 are considered to be the canonical cannabinoid receptors, there is significant overlap between cannabinoids and ligands of trp receptors. |
2020-10-01 |
2023-08-13 |
Not clear |
| Estefanía Moreno, Milena Cavic, Ana Krivokuca, Vicent Casadó, Enric Canel. The Endocannabinoid System as a Target in Cancer Diseases: Are We There Yet? Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31024307. |
the immense data load published on its dual role in both tumorigenesis and inhibition of tumor growth and metastatic spread has transformed the cannabinoid receptors cb1 (cb1r) and cb2 (cb2r), and other members of the endocannabinoid-like system, into attractive new targets for the treatment of various cancer subtypes. |
2020-10-01 |
2023-08-13 |
Not clear |
| Mikkel Søes Ibsen, David B Finlay, Monica Patel, Jonathan A Javitch, Michelle Glass, Natasha Lillia Grimse. Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31024316. |
cannabinoid cb1 and cb2 receptor-mediated arrestin translocation: species, subtype, and agonist-dependence. |
2020-10-01 |
2023-08-13 |
Not clear |
| Pramod Theetha Kariyanna, Perry Wengrofsky, Apoorva Jayarangaiah, Syed Haseeb, Louis Salciccioli, Sudhanva Hegde, Jonathan D Marmur, Yasmin Soliman, Sama Al-Bayati, Samy I McFarlan. Marijuana and Cardiac Arrhythmias: A Scoping Study. International journal of clinical research & trials. vol 4. issue 1. 2020-10-01. PMID:31579321. |
delta-9-tetrahydrocannabinol (thc) is the active psychotropic component of marijuana, which acts mainly on g-protein cannabinoid receptors cb1 and cb2. |
2020-10-01 |
2023-08-13 |
Not clear |
| Wei Bu, Huiling Ren, Yunping Deng, Nobel Del Mar, Natalie M Guley, Bob M Moore, Marcia G Honig, Anton Reine. Mild Traumatic Brain Injury Produces Neuron Loss That Can Be Rescued by Modulating Microglial Activation Using a CB2 Receptor Inverse Agonist. Frontiers in neuroscience. vol 10. 2020-09-30. PMID:27766068. |
we have also shown that these functional deficits are reduced by targeting microglia through their cannabinoid type-2 (cb2) receptors using 2-week daily administration of the cb2 inverse agonist smm-189. |
2020-09-30 |
2023-08-13 |
mouse |
| Waqas Jehangir, Michael Stanton, Rafay Khan, Puneet Sahgal, Abdalla Yousi. Did Cannabis Precipitate an STEMI in a Young Woman? Cardiology research. vol 6. issue 3. 2020-09-30. PMID:28197241. |
cannabis is a substance that contains compounds that bind cannabinoid receptors, cb1 and cb2. |
2020-09-30 |
2023-08-13 |
Not clear |
| Tommaso Cassano, Silvio Calcagnini, Lorenzo Pace, Federico De Marco, Adele Romano, Silvana Gaetan. Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28210207. |
in particular, the up-regulation of type-2 cannabinoid (cb2) receptors has been found in a number of neurodegenerative disorders. |
2020-09-30 |
2023-08-13 |
Not clear |
| Tomoyuki Kino, Toshiki Tomori, Rania Abutarboush, Paola Castri, Ye Chen, Frederick A Lenz, Richard M McCarron, Maria Spat. Effect of N-arachidonoyl-l-serine on human cerebromicrovascular endothelium. Biochemistry and biophysics reports. vol 8. 2020-09-30. PMID:28955964. |
however, in contrast to cannabinoids, ara-s binds weakly to its known classical receptors, cb1 and cb2, and is therefore considered to be a 'cannabinoid-like' substance. |
2020-09-30 |
2023-08-13 |
human |
| Tomoyuki Kino, Toshiki Tomori, Rania Abutarboush, Paola Castri, Ye Chen, Frederick A Lenz, Richard M McCarron, Maria Spat. Effect of N-arachidonoyl-l-serine on human cerebromicrovascular endothelium. Biochemistry and biophysics reports. vol 8. 2020-09-30. PMID:28955964. |
the present report demonstrates that ara-s enhances the fluorescence staining of both cannabinoid receptors (cb1 and cb2) in human brain endothelial cells (hbec). |
2020-09-30 |
2023-08-13 |
human |
| Ken Soderstrom, Eman Soliman, Rukiyah Van Dros. Cannabinoids Modulate Neuronal Activity and Cancer by CB1 and CB2 Receptor-Independent Mechanisms. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:29066974. |
cannabinoids modulate neuronal activity and cancer by cb1 and cb2 receptor-independent mechanisms. |
2020-09-30 |
2023-08-13 |
Not clear |
| Pinja Leimuranta, Leonard Khiroug, Rashid Giniatulli. Emerging Role of (Endo)Cannabinoids in Migraine. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:29740328. |
individual sections of this review cover key aspects of this topic, such as: (i) the current knowledge on the endocannabinoid system (ecs) with emphasis on expression of its components in migraine related structures; (ii) distinguishing peripheral from central site of action of cannabinoids, (iii) proposed mechanisms of migraine pain and control of nociceptive traffic by cannabinoids at the level of meninges and in brainstem, (iv) therapeutic targeting in migraine of monoacylglycerol lipase and fatty acid amide hydrolase, enzymes which control the level of endocannabinoids; (v) dual (possibly opposing) actions of cannabinoids via anti-nociceptive cb1 and cb2 and pro-nociceptive trpv1 receptors. |
2020-09-30 |
2023-08-13 |
Not clear |