| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fatemeh Mohammadpour, Seyed Nasser Ostad, Shima Aliebrahimi, Zahra Dama. Anti-invasion Effects of Cannabinoids Agonist and Antagonist on Human Breast Cancer Stem Cells. Iranian journal of pharmaceutical research : IJPR. vol 16. issue 4. 2020-10-01. PMID:29552056. |
recent studies have reported different effects of cannabinoids on cancer cells via cb1 and cb2 cannabinoid receptors. |
2020-10-01 |
2023-08-13 |
human |
| Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Sudhanva Hegde, Jonathan D Marmur, Perry Wengrofsky, Mena Yacoub, Michael Post, Samy I McFarlan. Marijuana Induced Type I Brugada Pattern: A Case Report. American journal of medical case reports. vol 6. issue 7. 2020-10-01. PMID:30294671. |
marijuana acts on cannabinoid receptors cb1, cb2 and another distinct endothelial receptor. |
2020-10-01 |
2023-08-13 |
Not clear |
| Chanté Muller, Paula Morales, Patricia H Reggi. Cannabinoid Ligands Targeting TRP Channels. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30697147. |
although cb1 and cb2 are considered to be the canonical cannabinoid receptors, there is significant overlap between cannabinoids and ligands of trp receptors. |
2020-10-01 |
2023-08-13 |
Not clear |
| Estefanía Moreno, Milena Cavic, Ana Krivokuca, Vicent Casadó, Enric Canel. The Endocannabinoid System as a Target in Cancer Diseases: Are We There Yet? Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31024307. |
the immense data load published on its dual role in both tumorigenesis and inhibition of tumor growth and metastatic spread has transformed the cannabinoid receptors cb1 (cb1r) and cb2 (cb2r), and other members of the endocannabinoid-like system, into attractive new targets for the treatment of various cancer subtypes. |
2020-10-01 |
2023-08-13 |
Not clear |
| Mikkel Søes Ibsen, David B Finlay, Monica Patel, Jonathan A Javitch, Michelle Glass, Natasha Lillia Grimse. Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31024316. |
cannabinoid cb1 and cb2 receptor-mediated arrestin translocation: species, subtype, and agonist-dependence. |
2020-10-01 |
2023-08-13 |
Not clear |
| Pramod Theetha Kariyanna, Perry Wengrofsky, Apoorva Jayarangaiah, Syed Haseeb, Louis Salciccioli, Sudhanva Hegde, Jonathan D Marmur, Yasmin Soliman, Sama Al-Bayati, Samy I McFarlan. Marijuana and Cardiac Arrhythmias: A Scoping Study. International journal of clinical research & trials. vol 4. issue 1. 2020-10-01. PMID:31579321. |
delta-9-tetrahydrocannabinol (thc) is the active psychotropic component of marijuana, which acts mainly on g-protein cannabinoid receptors cb1 and cb2. |
2020-10-01 |
2023-08-13 |
Not clear |
| Wei Bu, Huiling Ren, Yunping Deng, Nobel Del Mar, Natalie M Guley, Bob M Moore, Marcia G Honig, Anton Reine. Mild Traumatic Brain Injury Produces Neuron Loss That Can Be Rescued by Modulating Microglial Activation Using a CB2 Receptor Inverse Agonist. Frontiers in neuroscience. vol 10. 2020-09-30. PMID:27766068. |
we have also shown that these functional deficits are reduced by targeting microglia through their cannabinoid type-2 (cb2) receptors using 2-week daily administration of the cb2 inverse agonist smm-189. |
2020-09-30 |
2023-08-13 |
mouse |
| Waqas Jehangir, Michael Stanton, Rafay Khan, Puneet Sahgal, Abdalla Yousi. Did Cannabis Precipitate an STEMI in a Young Woman? Cardiology research. vol 6. issue 3. 2020-09-30. PMID:28197241. |
cannabis is a substance that contains compounds that bind cannabinoid receptors, cb1 and cb2. |
2020-09-30 |
2023-08-13 |
Not clear |
| Tommaso Cassano, Silvio Calcagnini, Lorenzo Pace, Federico De Marco, Adele Romano, Silvana Gaetan. Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28210207. |
in particular, the up-regulation of type-2 cannabinoid (cb2) receptors has been found in a number of neurodegenerative disorders. |
2020-09-30 |
2023-08-13 |
Not clear |
| Tomoyuki Kino, Toshiki Tomori, Rania Abutarboush, Paola Castri, Ye Chen, Frederick A Lenz, Richard M McCarron, Maria Spat. Effect of N-arachidonoyl-l-serine on human cerebromicrovascular endothelium. Biochemistry and biophysics reports. vol 8. 2020-09-30. PMID:28955964. |
however, in contrast to cannabinoids, ara-s binds weakly to its known classical receptors, cb1 and cb2, and is therefore considered to be a 'cannabinoid-like' substance. |
2020-09-30 |
2023-08-13 |
human |
| Tomoyuki Kino, Toshiki Tomori, Rania Abutarboush, Paola Castri, Ye Chen, Frederick A Lenz, Richard M McCarron, Maria Spat. Effect of N-arachidonoyl-l-serine on human cerebromicrovascular endothelium. Biochemistry and biophysics reports. vol 8. 2020-09-30. PMID:28955964. |
the present report demonstrates that ara-s enhances the fluorescence staining of both cannabinoid receptors (cb1 and cb2) in human brain endothelial cells (hbec). |
2020-09-30 |
2023-08-13 |
human |
| Ken Soderstrom, Eman Soliman, Rukiyah Van Dros. Cannabinoids Modulate Neuronal Activity and Cancer by CB1 and CB2 Receptor-Independent Mechanisms. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:29066974. |
cannabinoids modulate neuronal activity and cancer by cb1 and cb2 receptor-independent mechanisms. |
2020-09-30 |
2023-08-13 |
Not clear |
| Pinja Leimuranta, Leonard Khiroug, Rashid Giniatulli. Emerging Role of (Endo)Cannabinoids in Migraine. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:29740328. |
individual sections of this review cover key aspects of this topic, such as: (i) the current knowledge on the endocannabinoid system (ecs) with emphasis on expression of its components in migraine related structures; (ii) distinguishing peripheral from central site of action of cannabinoids, (iii) proposed mechanisms of migraine pain and control of nociceptive traffic by cannabinoids at the level of meninges and in brainstem, (iv) therapeutic targeting in migraine of monoacylglycerol lipase and fatty acid amide hydrolase, enzymes which control the level of endocannabinoids; (v) dual (possibly opposing) actions of cannabinoids via anti-nociceptive cb1 and cb2 and pro-nociceptive trpv1 receptors. |
2020-09-30 |
2023-08-13 |
Not clear |
| Pratima Dibba, Andrew A Li, George Cholankeril, Umair Iqbal, Chiranjeevi Gadiparthi, Muhammad Ali Khan, Donghee Kim, Aijaz Ahme. The Role of Cannabinoids in the Setting of Cirrhosis. Medicines (Basel, Switzerland). vol 5. issue 2. 2020-09-30. PMID:29890719. |
the endocannabinoid system comprises cannabinoid receptors 1 (cb1) and cannabinoid receptor 2 (cb2) and their ligands, endocannabinoids and exocannabinoids. |
2020-09-30 |
2023-08-13 |
mouse |
| Alyssa S Laun, Sarah H Shrader, Zhao-Hui Son. Novel inverse agonists for the orphan G protein-coupled receptor 6. Heliyon. vol 4. issue 11. 2020-09-30. PMID:30480157. |
gpr6, along with closely related orphan receptors gpr3 and gpr12, are phylogenetically related to cb1 and cb2 cannabinoid receptors. |
2020-09-30 |
2023-08-13 |
Not clear |
| Masahiro Kita, Yasuhisa Ano, Asuka Inoue, Junken Aok. Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells. Scientific reports. vol 9. issue 1. 2020-09-30. PMID:30816271. |
oleamide is an endocannabinoid and displays anti-inflammatory activity via the cannabinoid-2 (cb2) receptor; however, the mechanism underlying this anti-inflammatory activity has not been fully elucidated. |
2020-09-30 |
2023-08-13 |
human |
| Hesham M Mahmoud, Mona Osman, Osama Elshabrawy, Heba M I Abdallah, Ahmed Khairalla. AM-1241 CB2 Receptor Agonist Attenuates Inflammation, Apoptosis and Stimulate Progenitor Cells in Bile Duct Ligated Rats. Open access Macedonian journal of medical sciences. vol 7. issue 6. 2020-09-30. PMID:30976335. |
cannabinoid cb2 receptor activation has been reported to attenuate liver fibrosis in ccl4 exposed mice and also plays a potential role in liver regeneration in a mouse model of i/r and protection against alcohol-induced liver injury. |
2020-09-30 |
2023-08-13 |
mouse |
| Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Oleg Yurevich, Jonathan Francois, Denis Yusupov, Angelina Zhyvotovska, Louis Salciccioli, Sudhanva Hegde, Samy I McFarlan. Atrioventricular Nodal Reentrant Tachycardia Triggered by Marijuana Use: A Case Report and Review of the Literature. American journal of medical case reports. vol 7. issue 9. 2020-09-30. PMID:31396556. |
delta-9-tetrahydrocannabinol (thc) is the psychotropic component of marijuana, acting via cb1 and cb2 g-protein coupled cannabinoid receptors. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ahmed Sharaf, Leonore Mensching, Christina Keller, Sebastian Rading, Marina Scheffold, Lysann Palkowitsch, Nevena Djogo, Meriem Rezgaoui, Hans A Kestler, Barbara Moepps, Antonio Virgilio Failla, Meliha Karsa. Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome. Frontiers in molecular neuroscience. vol 12. 2020-09-30. PMID:31616248. |
the endocannabinoid system (ecs) consists particularly of cannabinoid receptors 1 and 2 (cb1 and cb2), their endogenous ligands, and enzymes that synthesize and degrade their ligands. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ali Parlar, Seyfullah Oktay Arslan, Muhammed Fatih Doğan, Saliha Ayşenur Çam, Alper Yalçin, Ebru Elibol, Mehmet Kaya Özer, Fatih Üçkardeş, Halil Kar. The exogenous administration of CB2 specific agonist, GW405833, inhibits inflammation by reducing cytokine production and oxidative stress. Experimental and therapeutic medicine. vol 16. issue 6. 2020-09-29. PMID:30542446. |
the present study aimed to investigate the role of cannabinoid 2 (cb2) receptors in a rat model of acute inflammation. |
2020-09-29 |
2023-08-13 |
rat |