| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Damian G Wheeler, Ellis Coope. Weak synaptic activity induces ongoing signaling to the nucleus that is enhanced by BDNF and suppressed by low-levels of nicotine. Molecular and cellular neurosciences. vol 26. issue 1. 2004-07-20. PMID:15121178. |
in addition, we show that bdnf, a molecule that has clear effects on synaptic plasticity, enhances this cre-dependent gene expression by acting upstream of nmda receptors. |
2004-07-20 |
2023-08-12 |
Not clear |
| Guido J Burbach, Rainer Hellweg, Carola A Haas, Domenico Del Turco, Uwe Deicke, Dorothee Abramowski, Mathias Jucker, Matthias Staufenbiel, Thomas Delle. Induction of brain-derived neurotrophic factor in plaque-associated glial cells of aged APP23 transgenic mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 10. 2004-05-28. PMID:15014117. |
brain-derived neurotrophic factor (bdnf) is a versatile neurotrophic factor that has been implicated in cell survival, cell differentiation, axonal growth, and activity-dependent synaptic plasticity. |
2004-05-28 |
2023-08-12 |
mouse |
| Aiguo Wu, Zhe Ying, Fernando Gomez-Pinill. The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition. The European journal of neuroscience. vol 19. issue 7. 2004-05-24. PMID:15078544. |
by using the antioxidant power of vitamin e, we performed studies to determine the role of oxidative stress as a mediator for the effects of bdnf on synaptic plasticity and cognition caused by consumption of the hf diet. |
2004-05-24 |
2023-08-12 |
rat |
| Aiguo Wu, Zhe Ying, Fernando Gomez-Pinill. The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition. The European journal of neuroscience. vol 19. issue 7. 2004-05-24. PMID:15078544. |
it is known that bdnf facilitates the synapse by modulating synapsin i and creb, which have been implicated in synaptic plasticity associated to learning and memory. |
2004-05-24 |
2023-08-12 |
rat |
| Aiguo Wu, Zhe Ying, Fernando Gomez-Pinill. The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition. The European journal of neuroscience. vol 19. issue 7. 2004-05-24. PMID:15078544. |
these results show that oxidative stress can interact with the bdnf system to modulate synaptic plasticity and cognitive function. |
2004-05-24 |
2023-08-12 |
rat |
| R Molteni, A Wu, S Vaynman, Z Ying, R J Barnard, F Gómez-Pinill. Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor. Neuroscience. vol 123. issue 2. 2004-05-12. PMID:14698750. |
a diet high in total fat (hf) reduces hippocampal levels of brain-derived neurotrophic factor (bdnf), a crucial modulator of synaptic plasticity, and a predictor of learning efficacy. |
2004-05-12 |
2023-08-12 |
Not clear |
| Kiyofumi Yamada, Toshitaka Nabeshim. Brain-derived neurotrophic factor/TrkB signaling in memory processes. Journal of pharmacological sciences. vol 91. issue 4. 2004-03-01. PMID:12719654. |
brain-derived neurotrophic factor (bdnf) plays an important role in activity-dependent synaptic plasticity such as long-term potentiation. |
2004-03-01 |
2023-08-12 |
Not clear |
| A Mantelas, A Stamatakis, I Kazanis, H Philippidis, F Stylianopoulo. Control of neuronal nitric oxide synthase and brain-derived neurotrophic factor levels by GABA-A receptors in the developing rat cortex. Brain research. Developmental brain research. vol 145. issue 2. 2004-02-19. PMID:14604759. |
and brain-derived neurotrophic factor (bdnf), both of which are involved in the control of synaptic plasticity and apoptosis. |
2004-02-19 |
2023-08-12 |
rat |
| Martha L Escobar, Yazmín Figueroa-Guzmán, Andrea Gómez-Palacio-Schjetna. In vivo insular cortex LTP induced by brain-derived neurotrophic factor. Brain research. vol 991. issue 1-2. 2004-01-22. PMID:14575905. |
recent studies suggest that brain-derived neurotrophic factor (bdnf) plays a critical role in long-term synaptic plasticity in the adult brain. |
2004-01-22 |
2023-08-12 |
rat |
| Martha L Escobar, Yazmín Figueroa-Guzmán, Andrea Gómez-Palacio-Schjetna. In vivo insular cortex LTP induced by brain-derived neurotrophic factor. Brain research. vol 991. issue 1-2. 2004-01-22. PMID:14575905. |
these findings support the concept that bdnf could be a synaptic messenger involved in activity-dependent synaptic plasticity. |
2004-01-22 |
2023-08-12 |
rat |
| Andrew P Hibbert, Stephen J Morris, Nabil G Seidah, Richard A Murph. Neurotrophin-4, alone or heterodimerized with brain-derived neurotrophic factor, is sorted to the constitutive secretory pathway. The Journal of biological chemistry. vol 278. issue 48. 2004-01-12. PMID:12970359. |
in contrast, brain-derived neurotrophic factor (bdnf) is processed in the regulated secretory pathway, stored in vesicles, and released in response to neuronal activity, consistent with its role in modulating synaptic plasticity. |
2004-01-12 |
2023-08-12 |
Not clear |
| J A Gorski, S A Balogh, J M Wehner, K R Jone. Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice. Neuroscience. vol 121. issue 2. 2003-12-19. PMID:14521993. |
brain-derived neurotrophic factor (bdnf) participates in synaptic plasticity and the adaptive changes in the strength of communication between neurons thought to underlie aspects of behavioral adaptation. |
2003-12-19 |
2023-08-12 |
mouse |
| R A Johnson, J S Rhodes, S L Jeffrey, T Garland, G S Mitchel. Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946694. |
voluntary wheel running in rats increases hippocampal brain-derived neurotrophic factor (bdnf) expression, a neurochemical important for neuronal survival, differentiation, connectivity and synaptic plasticity. |
2003-12-05 |
2023-08-12 |
mouse |
| Tami J Kingsbury, Peter D Murray, Linda L Bambrick, Bruce K Kruege. Ca(2+)-dependent regulation of TrkB expression in neurons. The Journal of biological chemistry. vol 278. issue 42. 2003-12-03. PMID:12900419. |
the neurotrophin brain-derived neurotrophic factor (bdnf), via activation of its receptor, tyrosine receptor kinase b (trkb), regulates a wide variety of cellular processes in the nervous system, including neuron survival and synaptic plasticity. |
2003-12-03 |
2023-08-12 |
mouse |
| Tami J Kingsbury, Peter D Murray, Linda L Bambrick, Bruce K Kruege. Ca(2+)-dependent regulation of TrkB expression in neurons. The Journal of biological chemistry. vol 278. issue 42. 2003-12-03. PMID:12900419. |
the coordinated regulation of bdnf and trkb by ca2+ may play a role in activity-dependent survival and synaptic plasticity by enhancing bdnf signaling in electrically active neurons. |
2003-12-03 |
2023-08-12 |
mouse |
| M Mizuno, K Yamada, N Takei, M H Tran, J He, A Nakajima, H Nawa, T Nabeshim. Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation. Molecular psychiatry. vol 8. issue 2. 2003-09-23. PMID:12610654. |
brain-derived neurotrophic factor (bdnf) plays a critical role in synaptic plasticity such as long-term potentiation (ltp), a form of synaptic correlate of learning and memory. |
2003-09-23 |
2023-08-12 |
rat |
| Yogesh Dwivedi, Hooriyah S Rizavi, Robert R Conley, Rosalinda C Roberts, Carol A Tamminga, Ghanshyam N Pande. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Archives of general psychiatry. vol 60. issue 8. 2003-09-10. PMID:12912764. |
brain-derived neurotrophic factor (bdnf), one of the most important neurotrophins, after binding with and activating receptor tyrosine kinase b (trk b), is directly involved in many physiological functions in the brain, including cell survival and synaptic plasticity. |
2003-09-10 |
2023-08-12 |
human |
| Kendra N Shaw, Sean Commins, Shane M O'Mar. Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factor. The European journal of neuroscience. vol 17. issue 11. 2003-09-04. PMID:12814375. |
here, we describe its role in synaptic plasticity and spatial learning in vivo via an effect on brain-derived neurotrophic factor (bdnf) and prostaglandin e2 (pge2; both measured by elisa). |
2003-09-04 |
2023-08-12 |
Not clear |
| Serge Mart. [Local effects of BDNF and synaptic plasticity: toward synaptic specificity]. Medecine sciences : M/S. vol 19. issue 5. 2003-09-04. PMID:12836388. |
[local effects of bdnf and synaptic plasticity: toward synaptic specificity]. |
2003-09-04 |
2023-08-12 |
Not clear |
| Rachel M Sherrard, Adrian J Bowe. Climbing fiber development: do neurotrophins have a part to play? Cerebellum (London, England). vol 1. issue 4. 2003-08-22. PMID:12879965. |
the function of bdnf is less certain, but experimental studies indicate that it has a role in climbing fiber innervation of purkinje cells, particularly synaptogenesis and synaptic plasticity. |
2003-08-22 |
2023-08-12 |
Not clear |