Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
A Mantelas, A Stamatakis, I Kazanis, H Philippidis, F Stylianopoulo. Control of neuronal nitric oxide synthase and brain-derived neurotrophic factor levels by GABA-A receptors in the developing rat cortex. Brain research. Developmental brain research. vol 145. issue 2. 2004-02-19. PMID:14604759. |
and brain-derived neurotrophic factor (bdnf), both of which are involved in the control of synaptic plasticity and apoptosis. |
2004-02-19 |
2023-08-12 |
rat |
Martha L Escobar, Yazmín Figueroa-Guzmán, Andrea Gómez-Palacio-Schjetna. In vivo insular cortex LTP induced by brain-derived neurotrophic factor. Brain research. vol 991. issue 1-2. 2004-01-22. PMID:14575905. |
recent studies suggest that brain-derived neurotrophic factor (bdnf) plays a critical role in long-term synaptic plasticity in the adult brain. |
2004-01-22 |
2023-08-12 |
rat |
Martha L Escobar, Yazmín Figueroa-Guzmán, Andrea Gómez-Palacio-Schjetna. In vivo insular cortex LTP induced by brain-derived neurotrophic factor. Brain research. vol 991. issue 1-2. 2004-01-22. PMID:14575905. |
these findings support the concept that bdnf could be a synaptic messenger involved in activity-dependent synaptic plasticity. |
2004-01-22 |
2023-08-12 |
rat |
Andrew P Hibbert, Stephen J Morris, Nabil G Seidah, Richard A Murph. Neurotrophin-4, alone or heterodimerized with brain-derived neurotrophic factor, is sorted to the constitutive secretory pathway. The Journal of biological chemistry. vol 278. issue 48. 2004-01-12. PMID:12970359. |
in contrast, brain-derived neurotrophic factor (bdnf) is processed in the regulated secretory pathway, stored in vesicles, and released in response to neuronal activity, consistent with its role in modulating synaptic plasticity. |
2004-01-12 |
2023-08-12 |
Not clear |
J A Gorski, S A Balogh, J M Wehner, K R Jone. Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice. Neuroscience. vol 121. issue 2. 2003-12-19. PMID:14521993. |
brain-derived neurotrophic factor (bdnf) participates in synaptic plasticity and the adaptive changes in the strength of communication between neurons thought to underlie aspects of behavioral adaptation. |
2003-12-19 |
2023-08-12 |
mouse |
R A Johnson, J S Rhodes, S L Jeffrey, T Garland, G S Mitchel. Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946694. |
voluntary wheel running in rats increases hippocampal brain-derived neurotrophic factor (bdnf) expression, a neurochemical important for neuronal survival, differentiation, connectivity and synaptic plasticity. |
2003-12-05 |
2023-08-12 |
mouse |
Tami J Kingsbury, Peter D Murray, Linda L Bambrick, Bruce K Kruege. Ca(2+)-dependent regulation of TrkB expression in neurons. The Journal of biological chemistry. vol 278. issue 42. 2003-12-03. PMID:12900419. |
the neurotrophin brain-derived neurotrophic factor (bdnf), via activation of its receptor, tyrosine receptor kinase b (trkb), regulates a wide variety of cellular processes in the nervous system, including neuron survival and synaptic plasticity. |
2003-12-03 |
2023-08-12 |
mouse |
Tami J Kingsbury, Peter D Murray, Linda L Bambrick, Bruce K Kruege. Ca(2+)-dependent regulation of TrkB expression in neurons. The Journal of biological chemistry. vol 278. issue 42. 2003-12-03. PMID:12900419. |
the coordinated regulation of bdnf and trkb by ca2+ may play a role in activity-dependent survival and synaptic plasticity by enhancing bdnf signaling in electrically active neurons. |
2003-12-03 |
2023-08-12 |
mouse |
M Mizuno, K Yamada, N Takei, M H Tran, J He, A Nakajima, H Nawa, T Nabeshim. Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation. Molecular psychiatry. vol 8. issue 2. 2003-09-23. PMID:12610654. |
brain-derived neurotrophic factor (bdnf) plays a critical role in synaptic plasticity such as long-term potentiation (ltp), a form of synaptic correlate of learning and memory. |
2003-09-23 |
2023-08-12 |
rat |
Yogesh Dwivedi, Hooriyah S Rizavi, Robert R Conley, Rosalinda C Roberts, Carol A Tamminga, Ghanshyam N Pande. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Archives of general psychiatry. vol 60. issue 8. 2003-09-10. PMID:12912764. |
brain-derived neurotrophic factor (bdnf), one of the most important neurotrophins, after binding with and activating receptor tyrosine kinase b (trk b), is directly involved in many physiological functions in the brain, including cell survival and synaptic plasticity. |
2003-09-10 |
2023-08-12 |
human |
Kendra N Shaw, Sean Commins, Shane M O'Mar. Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factor. The European journal of neuroscience. vol 17. issue 11. 2003-09-04. PMID:12814375. |
here, we describe its role in synaptic plasticity and spatial learning in vivo via an effect on brain-derived neurotrophic factor (bdnf) and prostaglandin e2 (pge2; both measured by elisa). |
2003-09-04 |
2023-08-12 |
Not clear |
Serge Mart. [Local effects of BDNF and synaptic plasticity: toward synaptic specificity]. Medecine sciences : M/S. vol 19. issue 5. 2003-09-04. PMID:12836388. |
[local effects of bdnf and synaptic plasticity: toward synaptic specificity]. |
2003-09-04 |
2023-08-12 |
Not clear |
Rachel M Sherrard, Adrian J Bowe. Climbing fiber development: do neurotrophins have a part to play? Cerebellum (London, England). vol 1. issue 4. 2003-08-22. PMID:12879965. |
the function of bdnf is less certain, but experimental studies indicate that it has a role in climbing fiber innervation of purkinje cells, particularly synaptogenesis and synaptic plasticity. |
2003-08-22 |
2023-08-12 |
Not clear |
Mariana Alonso, Monica R M Vianna, Ivan Izquierdo, Jorge H Medin. Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus. Cellular and molecular neurobiology. vol 22. issue 5-6. 2003-08-13. PMID:12585686. |
given that brain-derived neutrophic factor (bdnf) modulates both short-term synaptic function and activity-dependent synaptic plasticity in the adult hippocampus, here we examined signaling mechanisms in vivo in the hippocampus mediating bdnf modulation of long-term memory (ltm) formation of a one-trial fear-motivated learning task in rats. |
2003-08-13 |
2023-08-12 |
human |
A Wu, R Molteni, Z Ying, F Gomez-Pinill. A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain-derived neurotrophic factor. Neuroscience. vol 119. issue 2. 2003-07-30. PMID:12770552. |
bdnf has a strong effect on synaptic plasticity via the action of synapsin i and camp-response element-binding protein (creb), therefore, we assessed changes in synapsin i and creb in conjunction with bdnf. |
2003-07-30 |
2023-08-12 |
rat |
S D Kuipers, A Trentani, J A Den Boer, G J Ter Hors. Molecular correlates of impaired prefrontal plasticity in response to chronic stress. Journal of neurochemistry. vol 85. issue 5. 2003-07-24. PMID:12753089. |
significantly reduced phospho-creb expression in both cortical regions, considering its implication in brain-derived neurotrophic factor (bdnf) transcription, suggests reduced synaptic plasticity. |
2003-07-24 |
2023-08-12 |
rat |
Seung-Hee Lee, Jin-Hee Han, Jung-Hwan Choi, Eun-Young Huh, Yunhee Kim Kwon, Bong-Kiun Kaan. The effect of brain-derived neurotrophic factor on neuritogenesis and synaptic plasticity in Aplysia neurons and the hippocampal cell line HiB5. Molecules and cells. vol 15. issue 2. 2003-07-17. PMID:12803487. |
brain-derived neurotrophic factor (bdnf) plays a key role in the differentiation and neuritogenesis of developing neurons, and in the synaptic plasticity of mature neurons, in the mammalian nervous system. |
2003-07-17 |
2023-08-12 |
rat |
Seung-Hee Lee, Jin-Hee Han, Jung-Hwan Choi, Eun-Young Huh, Yunhee Kim Kwon, Bong-Kiun Kaan. The effect of brain-derived neurotrophic factor on neuritogenesis and synaptic plasticity in Aplysia neurons and the hippocampal cell line HiB5. Molecules and cells. vol 15. issue 2. 2003-07-17. PMID:12803487. |
we examined the specific effect of bdnf on neurite outgrowth and synaptic plasticity in cultured aplysia neurons and a multipotent rat hippocampal stem cell line (hib5). |
2003-07-17 |
2023-08-12 |
rat |
Seung-Hee Lee, Jin-Hee Han, Jung-Hwan Choi, Eun-Young Huh, Yunhee Kim Kwon, Bong-Kiun Kaan. The effect of brain-derived neurotrophic factor on neuritogenesis and synaptic plasticity in Aplysia neurons and the hippocampal cell line HiB5. Molecules and cells. vol 15. issue 2. 2003-07-17. PMID:12803487. |
our study indicates that mammalian bdnf has no significant effect on the neuritogenesis, neurotransmitter release, excitability, and synaptic plasticity of cultured aplysia neurons in our experimental conditions. |
2003-07-17 |
2023-08-12 |
rat |
Koji Ohira, Motoharu Hayash. Expression of TrkB subtypes in the adult monkey cerebellar cortex. Journal of chemical neuroanatomy. vol 25. issue 3. 2003-07-10. PMID:12706205. |
bdnf and its specific receptor trkb are concerned with synaptic plasticity as well as maintenance of the nervous system. |
2003-07-10 |
2023-08-12 |
monkey |