| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mariana Alonso, Monica R M Vianna, Ivan Izquierdo, Jorge H Medin. Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus. Cellular and molecular neurobiology. vol 22. issue 5-6. 2003-08-13. PMID:12585686. |
given that brain-derived neutrophic factor (bdnf) modulates both short-term synaptic function and activity-dependent synaptic plasticity in the adult hippocampus, here we examined signaling mechanisms in vivo in the hippocampus mediating bdnf modulation of long-term memory (ltm) formation of a one-trial fear-motivated learning task in rats. |
2003-08-13 |
2023-08-12 |
human |
| A Wu, R Molteni, Z Ying, F Gomez-Pinill. A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain-derived neurotrophic factor. Neuroscience. vol 119. issue 2. 2003-07-30. PMID:12770552. |
bdnf has a strong effect on synaptic plasticity via the action of synapsin i and camp-response element-binding protein (creb), therefore, we assessed changes in synapsin i and creb in conjunction with bdnf. |
2003-07-30 |
2023-08-12 |
rat |
| S D Kuipers, A Trentani, J A Den Boer, G J Ter Hors. Molecular correlates of impaired prefrontal plasticity in response to chronic stress. Journal of neurochemistry. vol 85. issue 5. 2003-07-24. PMID:12753089. |
significantly reduced phospho-creb expression in both cortical regions, considering its implication in brain-derived neurotrophic factor (bdnf) transcription, suggests reduced synaptic plasticity. |
2003-07-24 |
2023-08-12 |
rat |
| Seung-Hee Lee, Jin-Hee Han, Jung-Hwan Choi, Eun-Young Huh, Yunhee Kim Kwon, Bong-Kiun Kaan. The effect of brain-derived neurotrophic factor on neuritogenesis and synaptic plasticity in Aplysia neurons and the hippocampal cell line HiB5. Molecules and cells. vol 15. issue 2. 2003-07-17. PMID:12803487. |
brain-derived neurotrophic factor (bdnf) plays a key role in the differentiation and neuritogenesis of developing neurons, and in the synaptic plasticity of mature neurons, in the mammalian nervous system. |
2003-07-17 |
2023-08-12 |
rat |
| Seung-Hee Lee, Jin-Hee Han, Jung-Hwan Choi, Eun-Young Huh, Yunhee Kim Kwon, Bong-Kiun Kaan. The effect of brain-derived neurotrophic factor on neuritogenesis and synaptic plasticity in Aplysia neurons and the hippocampal cell line HiB5. Molecules and cells. vol 15. issue 2. 2003-07-17. PMID:12803487. |
we examined the specific effect of bdnf on neurite outgrowth and synaptic plasticity in cultured aplysia neurons and a multipotent rat hippocampal stem cell line (hib5). |
2003-07-17 |
2023-08-12 |
rat |
| Seung-Hee Lee, Jin-Hee Han, Jung-Hwan Choi, Eun-Young Huh, Yunhee Kim Kwon, Bong-Kiun Kaan. The effect of brain-derived neurotrophic factor on neuritogenesis and synaptic plasticity in Aplysia neurons and the hippocampal cell line HiB5. Molecules and cells. vol 15. issue 2. 2003-07-17. PMID:12803487. |
our study indicates that mammalian bdnf has no significant effect on the neuritogenesis, neurotransmitter release, excitability, and synaptic plasticity of cultured aplysia neurons in our experimental conditions. |
2003-07-17 |
2023-08-12 |
rat |
| Koji Ohira, Motoharu Hayash. Expression of TrkB subtypes in the adult monkey cerebellar cortex. Journal of chemical neuroanatomy. vol 25. issue 3. 2003-07-10. PMID:12706205. |
bdnf and its specific receptor trkb are concerned with synaptic plasticity as well as maintenance of the nervous system. |
2003-07-10 |
2023-08-12 |
monkey |
| P R Blanquet, J Mariani, P Dere. A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus. Neuroscience. vol 118. issue 2. 2003-06-16. PMID:12699783. |
brain-derived neurotrophic factor (bdnf) plays fundamental roles in synaptic plasticity in rat hippocampus. |
2003-06-16 |
2023-08-12 |
rat |
| P R Blanquet, J Mariani, P Dere. A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus. Neuroscience. vol 118. issue 2. 2003-06-16. PMID:12699783. |
recently, using rat hippocampal slices, we found that bdnf induces activation of calcium/calmodulin-dependent protein kinase 2 (camkii), a critical mediator of synaptic plasticity. |
2003-06-16 |
2023-08-12 |
rat |
| Julian Goggi, Ian A Pullar, Stephen L Carney, Henry F Bradfor. Signalling pathways involved in the short-term potentiation of dopamine release by BDNF. Brain research. vol 968. issue 1. 2003-06-04. PMID:12644273. |
brain-derived neurotrophic factor (bdnf) has been shown to modulate synaptic plasticity in the corpus striatum in vitro by activation of the tyrosine kinase linked receptor, trkb. |
2003-06-04 |
2023-08-12 |
rat |
| Marzia Malcangio, Volkmar Lessman. A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors. Trends in pharmacological sciences. vol 24. issue 3. 2003-04-08. PMID:12628355. |
in the schaffer collateral pathway of the hippocampus, binding of bdnf to high-affinity trkb receptors is essential for the induction of long-term potentiation, a specific type of synaptic plasticity. |
2003-04-08 |
2023-08-12 |
Not clear |
| Matylda Macias, Susanne Fehr, Anna Dwornik, Dorota Sulejczak, Maciej Wiater, Julita Czarkowska-Bauch, Malgorzata Skup, Melitta Schachne. Exercise increases mRNA levels for adhesion molecules N-CAM and L1 correlating with BDNF response. Neuroreport. vol 13. issue 18. 2003-04-04. PMID:12499861. |
these results suggest that exercise-induced rearrangements of the spinal network involve n-cam, l1 and bdnf, crucial in different aspects of synaptic plasticity and synapse formation. |
2003-04-04 |
2023-08-12 |
rat |
| Sophie Pezet, Marzia Malcangio, Stephen B McMaho. BDNF: a neuromodulator in nociceptive pathways? Brain research. Brain research reviews. vol 40. issue 1-3. 2003-04-01. PMID:12589922. |
in adulthood, bdnf has been suggested to act as an important modulator of synaptic plasticity. |
2003-04-01 |
2023-08-12 |
Not clear |
| Rachel Groth, Lin Aanonse. Spinal brain-derived neurotrophic factor (BDNF) produces hyperalgesia in normal mice while antisense directed against either BDNF or trkB, prevent inflammation-induced hyperalgesia. Pain. vol 100. issue 1-2. 2003-03-12. PMID:12435470. |
finally, with the accumulating evidence linking bdnf to synaptic plasticity, we investigated whether bdnf-induced hyperalgesia in normal mice involves the n-methyl-d-aspartate (nmda) receptor. |
2003-03-12 |
2023-08-12 |
mouse |
| Mariana Alonso, Monica R M Vianna, Amaicha M Depino, Tadeu Mello e Souza, Patricia Pereira, German Szapiro, Haydee Viola, Fernando Pitossi, Ivan Izquierdo, Jorge H Medin. BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Hippocampus. vol 12. issue 4. 2003-03-05. PMID:12201640. |
because brain-derived neutrophic factor (bdnf) modulates both short-term synaptic function and activity-dependent synaptic plasticity in the adult hippocampus, we examined the role of bdnf in stm and ltm formation of a hippocampal-dependent one-trial fear-motivated learning task in rats. |
2003-03-05 |
2023-08-12 |
human |
| Jeffrey W Grimm, Lin Lu, Teruo Hayashi, Bruce T Hope, Tsung-Ping Su, Yavin Shaha. Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 3. 2003-02-21. PMID:12574402. |
bdnf is involved in synaptic plasticity and was found to enhance responding for cues associated with natural rewards. |
2003-02-21 |
2023-08-12 |
rat |
| Sarah E Slack, Stephen W N Thompso. Brain-derived neurotrophic factor induces NMDA receptor 1 phosphorylation in rat spinal cord. Neuroreport. vol 13. issue 15. 2003-02-07. PMID:12395101. |
the nmda receptor and the neurotrophin brain-derived neurotrophic factor, bdnf, are involved in central sensitisation and synaptic plasticity in the spinal cord. |
2003-02-07 |
2023-08-12 |
rat |
| Masashi Yamada, Tadahiro Numakawa, Hisatsugu Koshimizu, Keiko Tanabe, Kazuyo Wada, Shinichi Koizumi, Hiroshi Hatanak. Distinct usages of phospholipase C gamma and Shc in intracellular signaling stimulated by neurotrophins. Brain research. vol 955. issue 1-2. 2003-01-31. PMID:12419535. |
nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3), members of the neurotrophin family, bind to and activate trka, trkb and trkc, respectively, members of the trk receptor tyrosine kinase family, to exert various effects including promotion of differentiation and survival, and regulation of synaptic plasticity in neuronal cells. |
2003-01-31 |
2023-08-12 |
Not clear |
| Paula C Ashe, Jennifer Chlan-Fourney, Augusto V Juorio, Xin-Min L. Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus. Brain research. vol 956. issue 1. 2003-01-29. PMID:12426055. |
the role of brain-derived neurotrophic factor (bdnf) in neurodevelopment, cell viability and synaptic plasticity led to the investigation of bdnf as a potential candidate molecule in the pathophysiology of schizophrenia. |
2003-01-29 |
2023-08-12 |
rat |
| Maija Castrén, Katariina E Lampinen, Riitta Miettinen, Eija Koponen, Ilkka Sipola, Cathy E Bakker, Ben A Oostra, Eero Castré. BDNF regulates the expression of fragile X mental retardation protein mRNA in the hippocampus. Neurobiology of disease. vol 11. issue 1. 2003-01-23. PMID:12460560. |
our data provide evidence that bdnf via trkb signaling decreases fmrp expression and suggest a role for fmrp in bdnf-induced synaptic plasticity. |
2003-01-23 |
2023-08-12 |
mouse |