| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Du, L Feng, F Yang, B L. Activity- and Ca(2+)-dependent modulation of surface expression of brain-derived neurotrophic factor receptors in hippocampal neurons. The Journal of cell biology. vol 150. issue 6. 2000-10-12. PMID:10995446. |
brain-derived neurotrophic factor (bdnf) has been shown to regulate neuronal survival and synaptic plasticity in the central nervous system (cns) in an activity-dependent manner, but the underlying mechanisms remain unclear. |
2000-10-12 |
2023-08-12 |
Not clear |
| T Araki, M Yamada, H Ohnishi, S I Sano, H Hatanak. BIT/SHPS-1 enhances brain-derived neurotrophic factor-promoted neuronal survival in cultured cerebral cortical neurons. Journal of neurochemistry. vol 75. issue 4. 2000-10-05. PMID:10987830. |
brain-derived neurotrophic factor (bdnf) activates a variety of signaling molecules to exert various functions in the nervous system, including neuronal differentiation, survival, and regulation of synaptic plasticity. |
2000-10-05 |
2023-08-12 |
rat |
| H Takag. [Neuronal cytokine involvement in synaptic plasticity]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 115. issue 4. 2000-10-02. PMID:10876804. |
these results suggested that the new synaptic sites, products of the bdnf induced l-ltp, will play an important role in synaptic plasticity (ex. |
2000-10-02 |
2023-08-12 |
Not clear |
| S A Nanda, K J Mac. Seizures and sensory stimulation result in different patterns of brain derived neurotrophic factor protein expression in the barrel cortex and hippocampus. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891580. |
brain-derived neurotrophic factor (bdnf) is important for the development and trophic support of neurons, and may be involved in controlling axonal sprouting and synaptic plasticity. |
2000-09-25 |
2023-08-12 |
rat |
| J L Hanover, Z J Huang, S Tonegawa, M P Stryke. Brain-derived neurotrophic factor overexpression induces precocious critical period in mouse visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 22. 2000-06-21. PMID:10559430. |
brain-derived neurotrophic factor (bdnf) is a candidate molecule for regulating activity-dependent synaptic plasticity on the grounds of its expression pattern in developing visual cortex and that of its receptor, trkb (castr¿n et al., 1992; bozzi et al., 1995; schoups et al., 1995; cabelli et al., 1996), as well as the modulation of these patterns by activity (castr¿n et al., 1992; bozzi et al., 1995; schoups et al., 1995). |
2000-06-21 |
2023-08-12 |
mouse |
| D Muller, Z Djebbara-Hannas, P Jourdain, L Vutskits, P Durbec, G Rougon, J Z Kis. Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 8. 2000-05-17. PMID:10760298. |
these results suggest that one action of psa-ncam could be to sensitize pyramidal neurons to bdnf, thereby modulating activity-dependent synaptic plasticity. |
2000-05-17 |
2023-08-12 |
mouse |
| J P Fawcett, M A Alonso-Vanegas, S J Morris, F D Miller, A F Sadikot, R A Murph. Evidence that brain-derived neurotrophic factor from presynaptic nerve terminals regulates the phenotype of calbindin-containing neurons in the lateral septum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 1. 2000-01-27. PMID:10627605. |
brain-derived neurotrophic factor (bdnf) is transported anterogradely in neurons of the cns and can be released by activity-dependent mechanisms to regulate synaptic plasticity. |
2000-01-27 |
2023-08-12 |
rat |
| W A Gottschalk, H Jiang, N Tartaglia, L Feng, A Figurov, B L. Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus. Learning & memory (Cold Spring Harbor, N.Y.). vol 6. issue 3. 1999-10-19. PMID:10492006. |
signaling mechanisms mediating bdnf modulation of synaptic plasticity in the hippocampus. |
1999-10-19 |
2023-08-12 |
Not clear |
| W A Gottschalk, H Jiang, N Tartaglia, L Feng, A Figurov, B L. Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus. Learning & memory (Cold Spring Harbor, N.Y.). vol 6. issue 3. 1999-10-19. PMID:10492006. |
although recent studies indicate that brain-derived neurotrophic factor (bdnf) plays an important role in hippocampal synaptic plasticity, the underlying signaling mechanisms remain largely unknown. |
1999-10-19 |
2023-08-12 |
Not clear |
| C Gaiddon, Y Larmet, E Trinh, A L Boutillier, B Sommer, J P Loeffle. Brain-derived neurotrophic factor exerts opposing effects on beta2-adrenergic receptor according to depolarization status of cerebellar neurons. Journal of neurochemistry. vol 73. issue 4. 1999-10-14. PMID:10501191. |
to investigate the molecular mechanisms underlying brain-derived neurotrophic factor (bdnf)-controlled synaptic plasticity, we studied beta2-adrenergic receptor (beta2-ar) expression in cultured cerebellar granule cells. |
1999-10-14 |
2023-08-12 |
Not clear |
| M Yuzaki, T Furuichi, K Mikoshiba, Y Kagaw. A stimulus paradigm inducing long-term desensitization of AMPA receptors evokes a specific increase in BDNF mRNA in cerebellar slices. Learning & memory (Cold Spring Harbor, N.Y.). vol 1. issue 4. 1999-09-29. PMID:10467600. |
these results indicate that bdnf may be coinduced with ltda and suggest that the slow and sustained increase of bdnf mrna might play a role in later phases of synaptic plasticity in the cerebellum. |
1999-09-29 |
2023-08-12 |
Not clear |
| J S Mu, W P Li, Z B Yao, X F Zho. Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats. Brain research. vol 835. issue 2. 1999-09-28. PMID:10415381. |
brain-derived neurotrophic factor (bdnf) is abundantly expressed in the hippocampus and cerebral cortex and is involved in synaptic plasticity and long-term potentiation (ltp). |
1999-09-28 |
2023-08-12 |
rat |
| S Y Lin, K Wu, G W Len, J L Xu, E S Levine, P C Suen, H T Mount, I B Blac. Brain-derived neurotrophic factor enhances association of protein tyrosine phosphatase PTP1D with the NMDA receptor subunit NR2B in the cortical postsynaptic density. Brain research. Molecular brain research. vol 70. issue 1. 1999-09-21. PMID:10381539. |
our recent studies revealed that brain-derived neurotrophic factor (bdnf) rapidly enhances tyrosine phosphorylation and dephosphorylation of the nmda receptor subunit, nr2b, in the postsynaptic density (psd), potentially regulating synaptic plasticity. |
1999-09-21 |
2023-08-12 |
rat |
| K M Huber, N B Sawtell, M F Bea. Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex. Neuropharmacology. vol 37. issue 4-5. 1999-05-26. PMID:9704998. |
the effects of brain-derived neurotrophic factor (bdnf) were investigated on synaptic transmission and two forms of activity-dependent synaptic plasticity, long-term potentiation (ltp) and long-term depression (ltd), in visual cortex slices prepared from young (p21 -28) rats. |
1999-05-26 |
2023-08-12 |
rat |
| K M Huber, N B Sawtell, M F Bea. Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex. Neuropharmacology. vol 37. issue 4-5. 1999-05-26. PMID:9704998. |
thus, bdnf treatment alters the relationship between stimulation frequency and synaptic plasticity in the visual cortex, shifting the modification threshold to the left. |
1999-05-26 |
2023-08-12 |
rat |
| K M Huber, N B Sawtell, M F Bea. Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex. Neuropharmacology. vol 37. issue 4-5. 1999-05-26. PMID:9704998. |
these data suggest that one role of bdnf during development of the visual cortex may be to modulate the properties of synaptic plasticity, enhancing synaptic strengthening and reducing synaptic weakening processes which contribute to the formation of specific synaptic connections. |
1999-05-26 |
2023-08-12 |
rat |
| H Fiumelli, D Jabaudon, P J Magistretti, J L Marti. BDNF stimulates expression, activity and release of tissue-type plasminogen activator in mouse cortical neurons. The European journal of neuroscience. vol 11. issue 5. 1999-05-26. PMID:10215917. |
brain-derived neurotrophic factor (bdnf) is a neurotrophic factor involved in neuronal development and synaptic plasticity. |
1999-05-26 |
2023-08-12 |
mouse |
| H Fiumelli, D Jabaudon, P J Magistretti, J L Marti. BDNF stimulates expression, activity and release of tissue-type plasminogen activator in mouse cortical neurons. The European journal of neuroscience. vol 11. issue 5. 1999-05-26. PMID:10215917. |
together these results suggest that activation of tpa by bdnf may contribute to structural changes associated with neuronal development or synaptic plasticity. |
1999-05-26 |
2023-08-12 |
mouse |
| S J Mowla, S Pareek, H F Farhadi, K Petrecca, J P Fawcett, N G Seidah, S J Morris, W S Sossin, R A Murph. Differential sorting of nerve growth factor and brain-derived neurotrophic factor in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 6. 1999-04-13. PMID:10066260. |
in contrast, brain-derived neurotrophic factor (bdnf) appears to be processed in the regulated secretory pathway of brain neurons and secreted in an activity-dependent manner to play a role in synaptic plasticity. |
1999-04-13 |
2023-08-12 |
Not clear |
| S Kinoshita, H Yasuda, N Taniguchi, R Katoh-Semba, H Hatanaka, T Tsumot. Brain-derived neurotrophic factor prevents low-frequency inputs from inducing long-term depression in the developing visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 6. 1999-04-13. PMID:10066265. |
if so, a shortage or blockade of bdnf might lead to another form of synaptic plasticity, long-term depression (ltd). |
1999-04-13 |
2023-08-12 |
rat |