| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suman Samaddar, Moqbel Ali Moqbel Redhwan, Mohan Muttanahally Eraiah, Raju Koner. Neurotrophins in Peripheral Neuropathy: Exploring Pathophysiological Mechanisms and Emerging Therapeutic Opportunities. CNS & neurological disorders drug targets. 2024-09-06. PMID:39238380. |
neurotrophins, including nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin- 3 (nt-3), and neurotrophin-4 (nt-4), are essential for neuronal survival, axonal growth, and synaptic plasticity. |
2024-09-06 |
2024-09-08 |
Not clear |
| Daniel Wolf, Maurilyn Ayon-Olivas, Michael Sendtne. BDNF-Regulated Modulation of Striatal Circuits and Implications for Parkinson's Disease and Dystonia. Biomedicines. vol 12. issue 8. 2024-08-29. PMID:39200225. |
activation of tropomyosin receptor kinase b (trkb) by bdnf is necessary for the induction of long-term potentiation (ltp), a form of synaptic plasticity, in the hippocampus and striatum. |
2024-08-29 |
2024-09-01 |
Not clear |
| Daniel Wolf, Maurilyn Ayon-Olivas, Michael Sendtne. BDNF-Regulated Modulation of Striatal Circuits and Implications for Parkinson's Disease and Dystonia. Biomedicines. vol 12. issue 8. 2024-08-29. PMID:39200225. |
given its essential role in promoting neuronal survival and meditating synaptic plasticity in the motor system, bdnf might have an important impact on the pathophysiology of neurodegenerative diseases, such as pd. |
2024-08-29 |
2024-09-01 |
Not clear |
| Jingxian Cao, Philip Gorwood, Nicolas Ramoz, Odile Viltar. The Role of Central and Peripheral Brain-Derived Neurotrophic Factor (BDNF) as a Biomarker of Anorexia Nervosa Reconceptualized as a Metabo-Psychiatric Disorder. Nutrients. vol 16. issue 16. 2024-08-29. PMID:39203753. |
beginning with an overview of bdnf's fundamental functions in neurodevelopment and synaptic plasticity, the review delves into recent clinical and preclinical evidence implicating bdnf in the pathophysiology of an. |
2024-08-29 |
2024-09-04 |
Not clear |
| Lorenzo Morè, Lucia Privitera, Marcia Lopes, J Simon C Arthur, Julie C Lauterborn, Sonia A L Corrêa, Bruno G Frenguell. MSK1 is required for the experience- and ampakine-dependent enhancement of spatial reference memory and reversal learning. Neuropharmacology. 2024-08-11. PMID:39128584. |
we have previously shown that msk1, by virtue of its ability to regulate gene transcription, converts the elevation of bdnf associated with environmental enrichment into molecular, synaptic, cognitive and genomic adaptations that underlie enrichment-induced enhanced synaptic plasticity and learning and memory, a property that msk1 retains across the lifespan. |
2024-08-11 |
2024-08-14 |
mouse |
| Farhad Sanaeifar, Sina Pourranjbar, Mohammad Pourranjbar, Sana Ramezani, Samira Rostami Mehr, Al-Hassan Soliman Wadan, Farnaz Khazeifar. Beneficial effects of physical exercise on cognitive-behavioral impairments and brain-derived neurotrophic factor alteration in the limbic system induced by neurodegeneration. Experimental gerontology. 2024-08-08. PMID:39116955. |
neurotrophins such as brain-derived neurotrophic factor (bdnf) are critical for neuron survival and synaptic plasticity, which is required for learning and memory. |
2024-08-08 |
2024-08-12 |
Not clear |
| Jiwon Park, Dong Yeol Kim, Eok-Soo Oh, Inn-Oc Ha. Light-Dependent Circadian Rhythm Governs O-GlcNAc Cycling to Influence Cognitive Function in Adult Zebrafish. Journal of pineal research. vol 76. issue 5. 2024-08-02. PMID:39092800. |
osmi-1 inhibited the expression of c-fos, bdnf, and calm1, key genes associated with brain function and synaptic plasticity, and decreased the binding of o-glcnacylated h2b and ogt to promoter regions of these genes. |
2024-08-02 |
2024-08-05 |
zebrafish |
| Mahmoud Hosseini, Fatemeh Seyedi, Mahdiyeh Hedayati-Moghadam, Mohammad Ali-Hassanzadeh, Hedyeh Askarpour, Somaieh Mansouri, Hadi Shafieemojaz, Yousef Baghchegh. The effects of PPARγ agonists on long‑termpotentiation and apoptosis in the hippocampusarea of juvenile hypothyroid rats. Acta neurobiologiae experimentalis. vol 84. issue 2. 2024-08-01. PMID:39087839. |
the aim of the present study was to evaluate the effect of rosiglitazone (rsg) or pioglitazone (pog) on the synaptic plasticity, neuronal apoptosis, brain-derived neurotrophic factor (bdnf), and nitric oxide (no) metabolites in the hippocampus of juvenile hypothyroid rats. |
2024-08-01 |
2024-08-03 |
rat |
| Smijin K Soman, Maryann Swain, Ruben K Dagd. BDNF-TrkB Signaling in Mitochondria: Implications for Neurodegenerative Diseases. Molecular neurobiology. 2024-07-19. PMID:39030441. |
brain-derived neurotrophic factor (bdnf) plays a pivotal role in neuronal development, synaptic plasticity, and overall neuronal health by binding to its receptor, tyrosine receptor kinase b (trkb). |
2024-07-19 |
2024-07-22 |
Not clear |
| Morgan K Foret, Chiara Orciani, Lindsay A Welikovitch, Chunwei Huang, A Claudio Cuello, Sonia Do Carm. Early oxidative stress and DNA damage in Aβ-burdened hippocampal neurons in an Alzheimer's-like transgenic rat model. Communications biology. vol 7. issue 1. 2024-07-14. PMID:39004677. |
we also found increased expression of synaptic plasticity genes (grin2b (nr2b), camkiiα, bdnf, c-fos, and homer1a) and increased protein levels of top2β. |
2024-07-14 |
2024-07-18 |
rat |
| Anastasia Bougea, Efthalia Angelopoulou, Efthimios Vasilopoulos, Philippos Gourzis, Sokratis Papageorgio. Emerging Therapeutic Potential of Fluoxetine on Cognitive Decline in Alzheimer's Disease: Systematic Review. International journal of molecular sciences. vol 25. issue 12. 2024-06-27. PMID:38928248. |
fluoxetine promoted neurogenesis and enhanced synaptic plasticity in preclinical models of ad, through a decrease in aβ pathology and increase in bdnf, by activating diverse pathways (such as the daf-16-mediated, tgf-beta1, ilk-akt-gsk3beta, and creb/p-creb/bdnf). |
2024-06-27 |
2024-06-29 |
human |
| Emily Z Huie, Xin Yang, Mengia S Rioult-Pedotti, Mandar Naik, Yu-Wen Alvin Huang, Jill L Silverman, John Marshal. Peptidomimetic inhibitors targeting TrkB/PSD-95 signaling improves cognition and seizure outcomes in an Angelman Syndrome mouse model. bioRxiv : the preprint server for biology. 2024-06-19. PMID:38895218. |
brain-derived neurotrophic factor (bdnf), and its receptor trkb, have a well-established role as regulators of synaptic plasticity, dendritic outgrowth, dendritic spine formation and maintenance. |
2024-06-19 |
2024-06-21 |
mouse |
| Sasa Wang, Xinlei Zhang, Yuru Zhao, Haoxuan Lv, Pengyu Li, Zhihao Zhang, Xiaomeng Qia. BCI Improves Alcohol-Induced Cognitive and Emotional Impairments by Restoring pERK-BDNF. Journal of molecular neuroscience : MN. vol 74. issue 3. 2024-06-18. PMID:38890235. |
extracellular regulated protein kinases (erk) maintain neuronal survival, growth, and regulation of synaptic plasticity by phosphorylating specific transcription factors to regulate expression of brain-derived neurotrophic factor (bdnf). |
2024-06-18 |
2024-06-21 |
mouse |
| Sri-Arun Iamjan, Siriluk Veerasakul, Gavin P Reynolds, Samur Thanoi, Sutisa Nudmamud-Thano. Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse. Neuroscience letters. 2024-06-17. PMID:38885757. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophin family, plays key roles in neuronal protection and synaptic plasticity. |
2024-06-17 |
2024-06-21 |
rat |
| Gayathri Rajamanickam, Andy Thiam Huat Lee, Ping Lia. Role of Brain Derived Neurotrophic Factor and Related Therapeutic Strategies in Central Post-Stroke Pain. Neurochemical research. 2024-06-10. PMID:38856889. |
brain-derived neurotrophic factor (bdnf) is vital for synaptic plasticity, cell persistence, and neuronal development in peripheral and central nervous systems (cns). |
2024-06-10 |
2024-06-14 |
Not clear |
| Ayman Alzu'bi, Ejlal Abu-El-Rub, Fatimah Almahasneh, Lena Tahat, Rabaa Y Athamneh, Ramada Khasawneh, Hiba Alzoubi, Doaa S Ghorab, Rawan Almazari, Mazhar Salim Al Zoubi, Raed M Al-Zoub. Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice. Neurotoxicology. vol 103. 2024-06-08. PMID:38823587. |
these findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (bdnf), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. |
2024-06-08 |
2024-06-11 |
mouse |
| Juhyun Son. BDNF Signaling in Vascular Dementia and Its Effects on Cerebrovascular Dysfunction, Synaptic Plasticity, and Cholinergic System Abnormality. Journal of lipid and atherosclerosis. vol 13. issue 2. 2024-06-03. PMID:38826183. |
bdnf signaling in vascular dementia and its effects on cerebrovascular dysfunction, synaptic plasticity, and cholinergic system abnormality. |
2024-06-03 |
2024-06-05 |
human |
| Danbi Jo, Seo Yeon Ahn, Seo Yoon Choi, Yoonjoo Choi, Dong Hoon Lee, Juhyun Son. Positive Effects of Adiponectin, BDNF, and GLP-1 on Cortical Neurons Counteracting Palmitic Acid Induced Neurotoxicity. Clinical nutrition research. vol 13. issue 2. 2024-05-24. PMID:38784850. |
recently, adiponectin, brain-derived neurotrophic factor (bdnf), and glucose-like peptide-1 (glp-1) have been investigated to find therapeutic solutions for metabolic syndrome, with findings suggesting that they are involved in insulin sensitivity, enhanced lipid profiles, increased neuronal survival, and improved synaptic plasticity. |
2024-05-24 |
2024-05-27 |
Not clear |
| Danbi Jo, Seo Yeon Ahn, Seo Yoon Choi, Yoonjoo Choi, Dong Hoon Lee, Juhyun Son. Positive Effects of Adiponectin, BDNF, and GLP-1 on Cortical Neurons Counteracting Palmitic Acid Induced Neurotoxicity. Clinical nutrition research. vol 13. issue 2. 2024-05-24. PMID:38784850. |
our findings demonstrate the therapeutic potential of adiponectin, bdnf, and glp-1 in enhancing synaptic plasticity within brains affected by metabolic imbalance. |
2024-05-24 |
2024-05-27 |
Not clear |
| Zhenhuan Wang, Qi Hu, Chao Tian, Ruipeng Wang, Qingyan Jiao, Feng Chen, Tongrui Wu, Jialiang Wang, Yuxuan Zhu, Aili Liu, Wei Zhang, Jie Li, Hui She. Prophylactic Effects of n-Acethylcysteine on Inflammation-induced Depression-like Behaviors in Mice. Neuroscience. 2024-05-16. PMID:38729599. |
this study sought to determine whether nac use could mitigate inflammatory depressive behavior through the enhancement of synaptic transmission, synaptic plasticity, and increasing levels of brain-derived neurotrophic factor (bdnf). |
2024-05-16 |
2024-05-27 |
mouse |