| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valerio Ricci, Domenico de Berardis, Giovanni Martinotti, Giuseppe Main. Neurotrophic Factors In Cannabis-Induced Psychosis: An Update. Current topics in medicinal chemistry. 2023-08-30. PMID:37644743. |
in particular, nerve growth factor (ngf) plays an important role in the survival and function of cholinergic neurons while brain-derived neurotrophic factor (bdnf) is involved in synaptic plasticity and the maintenance of midbrain dopaminergic and cholinergic neurons. |
2023-08-30 |
2023-09-07 |
Not clear |
| Annela Avarlaid, Eli-Eelika Esvald, Indrek Koppel, Annabel Parkman, Anna Zhuravskaya, Eugene V Makeyev, Jürgen Tuvikene, Tõnis Timmus. An 840 kb distant upstream enhancer is a crucial regulator of catecholamine-dependent expression of the Bdnf gene in astrocytes. Glia. 2023-08-26. PMID:37632136. |
brain-derived neurotrophic factor (bdnf) plays a fundamental role in the developing and adult nervous system, contributing to neuronal survival, differentiation, and synaptic plasticity. |
2023-08-26 |
2023-09-07 |
Not clear |
| Simone Tambaro, Sumonto Mitra, Ruchi Gera, Bengt Linderoth, Lars U Wahlberg, Taher Darreh-Shori, Homira Behbahani, Per Nilsson, Maria Eriksdotte. Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to App Alzheimer's research & therapy. vol 15. issue 1. 2023-08-21. PMID:37596686. |
brain-derived neurotrophic factor (bdnf) is a key neurotrophin involved in the learning and memory process, with a crucial role in synaptic plasticity and neuronal survival. |
2023-08-21 |
2023-09-07 |
mouse |
| Hamed Alizadeh Pahlavan. Exercise therapy to prevent and treat Alzheimer's disease. Frontiers in aging neuroscience. vol 15. 2023-08-21. PMID:37600508. |
aerobic exercise significantly increases plasma levels of bdnf, nerve growth factor, synaptic plasticity, motor activity, spatial memory, and exploratory behavior in ad subjects. |
2023-08-21 |
2023-09-07 |
human |
| Hong Su, Haiyan Chen, Xi Zhang, Shengyong Su, Jing Li, Yanjun Guo, Qiongxiao Wang, Caiyun Xie, Pu Yan. Electroacupuncture ameliorates pain in cervical spondylotic radiculopathy rat by inhibiting the CaMKII/CREB/BDNF signaling pathway and regulating spinal synaptic plasticity. Brain and behavior. 2023-08-07. PMID:37548586. |
recent studies have shown that the calmodulin-dependent protein kinase ii (camkii)/camp-response element binding protein (creb)/brain-derived neurotrophic factor (bdnf) signaling pathway mediates central sensitization through its involvement in spinal cord synaptic plasticity. |
2023-08-07 |
2023-08-14 |
rat |
| Lv-Ping Zhuang, Wei-Jie Gao, Liu-Lv Fang, Gui-Rong Zeng, Qin-Yong Ye, Xiao-Man Dai, Jing Zhang, Xiao-Chun Che. HnRNPK is involved in stress-induced depression-like behavior via ERK-BDNF pathway in mice. Neurochemistry international. 2023-08-05. PMID:37543308. |
available literature indicates that it can regulate dendritic spine density through the extracellular signal-regulating kinase (erk) - brain-derived neurotrophic factor (bdnf) pathway, which is crucial to retain the synaptic plasticity in patients with major depressive disorder (mdd) and mouse depression models. |
2023-08-05 |
2023-08-14 |
mouse |
| Wanbing Wang, Yanzhong Li, Fangling Ma, Xuan Sheng, Kai Chen, Rengong Zhuo, Chen Wang, Honghua Zheng, Yun-Wu Zhang, Guojun Bu, Xiao-Fen Chen, Li Zhon. Microglial repopulation reverses cognitive and synaptic deficits in an Alzheimer's disease model by restoring BDNF signaling. Brain, behavior, and immunity. 2023-07-23. PMID:37482204. |
lastly, we demonstrated that the repopulation restores the expression of brain-derived neurotrophic factor (bdnf) in microglia, thereby contributing to synaptic plasticity. |
2023-07-23 |
2023-08-14 |
mouse |
| Mayuri N Tuwar, Wei-Hung Chen, Arthur M Chiwaya, Hsu-Ling Yeh, Minh H Nguyen, Chyi-Huey Ba. Brain-Derived Neurotrophic Factor (BDNF) and Translocator Protein (TSPO) as Diagnostic Biomarkers for Acute Ischemic Stroke. Diagnostics (Basel, Switzerland). vol 13. issue 13. 2023-07-14. PMID:37443691. |
brain-derived neurotrophic factor (bdnf) interacts with tropomyosin-related kinase b (trkb) to promote neuronal growth, survival, differentiation, neurotransmitter release, and synaptic plasticity. |
2023-07-14 |
2023-08-14 |
Not clear |
| Beatriz Benítez-Temiño, Rosendo G Hernández, Rosa R de la Cruz, Angel M Pasto. BDNF Influence on Adult Terminal Axon Sprouting after Partial Deafferentation. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445838. |
bdnf is a neurotrophin family member implicated in many different neuronal functions, from neuronal survival during development to synaptic plasticity associated with processes of learning and memory. |
2023-07-14 |
2023-08-14 |
Not clear |
| Igor Henrique Rodrigues de Paiva, Rodrigo Soares da Silva, Ingrid Prata Mendonça, Eduardo Duarte-Silva, José Roberto Botelho de Souza, Christina Alves Peixot. Fructooligosaccharide (FOS) and Galactooligosaccharide (GOS) Improve Neuroinflammation and Cognition By Up-regulating IRS/PI3K/AKT Signaling Pathway in Diet-induced Obese Mice. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023-06-29. PMID:37382830. |
these obese mice also showed activation of microglia and astrocytes and significant immunoreactivity of neuroinflammatory and apoptosis markers, such as tnf-α, cox-2, and caspase-3, in addition to lower expression of neurogenesis and synaptic plasticity markers, such as neun, ki-67, creb-p, and bdnf. |
2023-06-29 |
2023-08-14 |
mouse |
| Igor Henrique Rodrigues de Paiva, Rodrigo Soares da Silva, Ingrid Prata Mendonça, Eduardo Duarte-Silva, José Roberto Botelho de Souza, Christina Alves Peixot. Fructooligosaccharide (FOS) and Galactooligosaccharide (GOS) Improve Neuroinflammation and Cognition By Up-regulating IRS/PI3K/AKT Signaling Pathway in Diet-induced Obese Mice. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023-06-29. PMID:37382830. |
in addition, fos and gos promoted synaptic plasticity by increasing neun, p-creb, bdnf, and ki-67, restoring spatial learning ability and memory. |
2023-06-29 |
2023-08-14 |
mouse |
| Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
given previously known effects of brain-derived neurotrophic factor (bdnf) in regulating synaptic plasticity and learning and memory, we investigated the effect of chronic alcohol consumption on spatial memory impairment in both sexes and changes in bdnf signaling in the hippocampus. |
2023-06-12 |
2023-08-14 |
mouse |
| Ram Kumar Manthari, Prathyusha Koyya, Santhi Latha Pandrang. Brain-Derived Neurotrophic Factor - The Protective Agent Against Neurological Disorders. CNS & neurological disorders drug targets. 2023-06-08. PMID:37287291. |
one among them is the brain-derived neurotrophic factor (bdnf), which performs several vital functions, enhancing synaptic plasticity and assisting in the emergence of long-term thoughts. |
2023-06-08 |
2023-08-14 |
Not clear |
| Shiji Zhang, Weng Fu, Xiaoe Jia, Rengui Bade, Xiaolei Liu, Yabin Xie, Wei Xie, Shuyuan Jiang, Guo Sha. Hypoxic Preconditioning Modulates BDNF and Its Signaling through DNA Methylation to Promote Learning and Memory in Mice. ACS chemical neuroscience. 2023-06-08. PMID:37289948. |
brain-derived neurotrophic factor (bdnf) activates its signaling upon binding to the tropomyosin-related kinase b (trkb) receptor, which is involved in neuronal growth, differentiation, and synaptic plasticity. |
2023-06-08 |
2023-08-14 |
mouse |
| Pavan Thapak, Gregory Smith, Zhe Ying, Afshin Paydar, Neil Harris, Fernando Gomez-Pinill. The BDNF mimetic R-13 attenuates TBI pathogenesis using TrkB-related pathways and bioenergetics. Biochimica et biophysica acta. Molecular basis of disease. 2023-06-07. PMID:37286142. |
additionally, r13 was found to counteract reductions in molecules associated with bdnf signaling (p-trkb, p-pi3k, p-akt), synaptic plasticity (glur2, psd95, synapsin i) as well as bioenergetic components such as mitophagy (sod, pgc-1α, pink1, parkin, bnip3, and lc3) and real-time mitochondrial respiratory capacity. |
2023-06-07 |
2023-08-14 |
Not clear |
| Bradley John Baranowski, Ahmad Mohammad, Michael S Finch, Alex Brown, Roopan Dhaliwal, Daniel M Marko, Paul J LeBlanc, Cheryl M McCormick, Val A Fajardo, Rebecca E K MacPherso. Exercise training and BDNF injections alter APP processing enzymes and improve cognition. Journal of applied physiology (Bethesda, Md. : 1985). 2023-06-01. PMID:37262102. |
bdnf is an exercise-induced neurotrophin known for its role in synaptic plasticity, neurite growth, and neuronal survival. |
2023-06-01 |
2023-08-14 |
Not clear |
| Zijuan Zhang, Ziyang Yu, Ye Yuan, Jing Yang, Shijie Wang, He Ma, Li Hao, Jinlian Ma, Zhonghua Li, Zhenqiang Zhang, Christian Hölsche. Cholecystokinin Signaling can Rescue Cognition and Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer's Disease. Molecular neurobiology. 2023-05-29. PMID:37247071. |
our study found that the cck analogue could effectively improve spatial learning and memory, enhance synaptic plasticity in the hippocampus, normalize synapse numbers and morphology and the levels of key synaptic proteins, up-regulate the pi3k/akt signaling pathway and normalize pka, creb, bdnf and trkb receptor levels in app/ps1 mice. |
2023-05-29 |
2023-08-14 |
mouse |
| Juan Carlos Arévalo, Rubén Deogracia. Mechanisms Controlling the Expression and Secretion of BDNF. Biomolecules. vol 13. issue 5. 2023-05-27. PMID:37238659. |
among them, bdnf plays a crucial role in the development and correct maintenance of brain circuits and synaptic plasticity as well as in neurodegenerative diseases. |
2023-05-27 |
2023-08-14 |
Not clear |
| Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xian. Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson's Disease. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175535. |
moreover, treadmill exercise enhanced the synaptic plasticity of hippocampal pyramidal neurons via increased dopamine levels and bdnf in the pd mice. |
2023-05-14 |
2023-08-14 |
mouse |
| Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xian. Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson's Disease. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175535. |
the direct protective effect of fndc5 is achieved by promoting the secretion of bdnf in the hippocampal neurons via binding the integrin αvβ5 receptor, thereby improving synaptic plasticity. |
2023-05-14 |
2023-08-14 |
mouse |