| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pranglada Jearjaroen, Phakkawat Thangwong, Chainarong Tocharus, Anusorn Lungkaphin, Waraluck Chaichompoo, Jaranwit Srijun, Apichart Suksamrarn, Jiraporn Tocharu. Hexahydrocurcumin Attenuates Neuronal Injury and Modulates Synaptic Plasticity in Chronic Cerebral Hypoperfusion in Rats. Molecular neurobiology. 2023-12-12. PMID:38087168. |
moreover, hhc or piracetam also improved synaptic plasticity via the brain-derived neurotrophic factor (bdnf)/tyrosine receptor kinase b (trkb)/camp responsive element binding protein (creb) signaling pathway. |
2023-12-12 |
2023-12-17 |
rat |
| Ruyu Wang, Yiwei Chen, Zhiying Wang, Baorui Cao, Jinxin Du, Tingting Deng, Meina Yang, Jinxiang Ha. Antidepressant effect of licorice total flavonoids and liquiritin: A review. Heliyon. vol 9. issue 11. 2023-12-11. PMID:38074876. |
studies have shown that lf and liquiritin can exert their antidepressant effects by improving depressive behavior, regulating endocrine and hypothalamic-pituitary-adrenal (hpa) axis function, affecting the brain-derived neurotrophic factor (bdnf)/tyrosine kinase b (trkb) signaling pathway, enhancing synaptic plasticity, increasing monoamine neurotransmitter levels, protecting nerve cells, reducing inflammation, preventing apoptosis, reducing oxidation and other ways. |
2023-12-11 |
2023-12-17 |
Not clear |
| Robert Shen, Christian Ardianto, Celia Celia, Veronika Maria Sidharta, Poppy Kristina Sasmita, Irawan Satriotomo, Yuda Turan. Brain-derived neurotrophic factor interplay with oxidative stress: neuropathology approach in potential biomarker of Alzheimer's disease. Dementia & neuropsychologia. vol 17. 2023-12-06. PMID:38053647. |
oxidative stress, as a molecular hallmark that causes susceptibility in ad, interplays to other ad-related neuropathology cascades and decreases the expression of central and circulation brain-derived neurotrophic factor (bdnf), an essential neurotrophin that serves as nerve development and survival, and synaptic plasticity in ad. |
2023-12-06 |
2023-12-10 |
Not clear |
| Udaykanth Suryavanshi, Kiran Kumar Angadi, V Sudhakar Reddy, G Bhanuprakash Reddy. Neuroprotective role of vitamin B12 in streptozotocin-induced type 1 diabetic rats. Chemico-biological interactions. 2023-12-04. PMID:38049026. |
further, b12 supplementation restored the markers of neurotrophic support (bdnf, ngf, and gdnf), and synaptic plasticity (syp, and psd-95) in diabetic rats. |
2023-12-04 |
2023-12-10 |
rat |
| Mizhu Sun, Qingmeng Zheng, Lulu Wang, Runzhi Wang, Hengzhen Cui, Xinlei Zhang, Chen Xu, Fangyuan Yin, Hongtao Yan, Xiaomeng Qia. Alcohol Consumption During Adolescence Alters the Cognitive Function in Adult Male Mice by Persistently Increasing Levels of DUSP6. Molecular neurobiology. 2023-11-17. PMID:37978157. |
extracellular signal-regulated kinase (erk) is involved in the synaptic plasticity and pathological brain injury by regulating the expression of cyclic adenosine monophosphate response element binding protein (creb) and brain-derived neurotrophic factor (bdnf). |
2023-11-17 |
2023-11-20 |
mouse |
| Nitasha Rana, Lakshay Kapil, Charan Singh, Arti Sing. Modeling Huntington's disease: An insight on in-vitro and in-vivo models. Behavioural brain research. 2023-11-12. PMID:37952684. |
several other molecular mechanisms have also been implicated in hd pathology, including brain-derived neurotrophic factor (bdnf), mitochondrial dysfunction, and altered synaptic plasticity in central spiny neurons. |
2023-11-12 |
2023-11-20 |
Not clear |
| Nuo Chen, Ming Zhao, Yaxin Guo, Nan Wu, Baihui Cao, Bing Zhan, Tian Zhou, Yubin Li, Faliang Zhu, WanJun Chen, Yan Li, Lining Zhan. D-mannose is a rapid inducer of ACSS2 to trigger rapid and long-lasting antidepressant responses through augmenting BDNF and TPH2 levels. Translational psychiatry. vol 13. issue 1. 2023-11-02. PMID:37914710. |
the potentiation of synaptic plasticity and serotonin generation by brain-derived neurotrophic factor (bdnf) and tryptophan hydroxylase 2 (tph2) is well characterized to facilitate rapid and long-lasting antidepressant actions. |
2023-11-02 |
2023-11-08 |
mouse |
| Anton Shkundin, Angelos Halari. Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder. Journal of personalized medicine. vol 13. issue 9. 2023-09-28. PMID:37763162. |
brain-derived neurotrophic factor (bdnf) is crucial for various aspects of neuronal development and function, including synaptic plasticity, neurotransmitter release, and supporting neuronal differentiation, growth, and survival. |
2023-09-28 |
2023-10-07 |
Not clear |
| Jie Yuan, Jing Gao, Kai-Qi Su, Xiao-Dong Fen. [Electroacupuncture improves learning and memory impairment and enhances hippocampal synaptic plasticity through BDNF/TRKB/CREB signaling pathway in cerebral ischemia-reperfusion injury rats]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 9. 2023-09-20. PMID:37730254. |
to observe the effect of electroacupuncture on brain-derived neurotrophin factor (bdnf) / tyrosine kinase receptor b (trkb) / cyclic adenosine monophosphate response element binding protein (creb) pathway, synaptic plasticity marker protein and synaptic ultrastructure in the hippocampus of rats with learning and memory impairment induced by cerebral ischemia reperfusion (ir), so as to explore its mechanisms underlying improvement of cognitive impairment after stroke. |
2023-09-20 |
2023-10-07 |
rat |
| Xiqi Hu, Jun Peng, Wei Tang, Ying Xia, Peipei Son. A circadian rhythm-restricted diet regulates autophagy to improve cognitive function and prolong lifespan. Bioscience trends. 2023-09-18. PMID:37722875. |
in addition, a diet restricted to the circadian rhythm induces increased expression of brain-derived neurotrophic factor (bdnf) in the forebrain region, regulating autophagy and increasing synaptic plasticity, thus enhancing cognitive function. |
2023-09-18 |
2023-10-07 |
Not clear |
| Cristina Lao-Peregrin, Guoqing Xiang, Jihye Kim, Ipsit Srivastava, Alexandra B Fall, Danielle M Gerhard, Piia Kohtala, Daegeon Kim, Minseok Song, Mikel Garcia-Marcos, Joshua Levitz, Francis S Le. Synaptic plasticity via receptor tyrosine kinase/G protein-coupled receptor crosstalk. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693535. |
we find that the receptor tyrosine kinase (rtk), trkb, and the g protein-coupled receptor (gpcr), metabotropic glutamate receptor 5 (mglur5), together mediate a novel form of hippocampal synaptic plasticity in response to brain-derived neurotrophic factor (bdnf). |
2023-09-11 |
2023-10-07 |
Not clear |
| Maryann Swain, Smijin K Soman, Kylea Tapia, Raul Y Dagda, Ruben K Dagd. Brain-derived neurotrophic factor protects neurons by stimulating mitochondrial function through protein kinase A. Journal of neurochemistry. 2023-09-09. PMID:37688457. |
brain-derived neurotrophic factor protects neurons by stimulating mitochondrial function through protein kinase a. brain-derived neurotrophic factor (bdnf) stimulates dendrite outgrowth and synaptic plasticity by activating downstream protein kinase a (pka) signaling. |
2023-09-09 |
2023-10-07 |
Not clear |
| Jiao Liu, Jing Tao, Guiyan Cai, Jie Chen, Lei Zhao, Yajun Wang, Shurui Xu, Ruilin Chen, Li Hu, Jin Cao, Lidian Chen, Yiheng T. The altered hippocampal functional connectivity and serum brain-derived neurotrophic factor level predict cognitive decline in patients with knee osteoarthritis. Cerebral cortex (New York, N.Y. : 1991). 2023-09-01. PMID:37653604. |
the altered hippocampal functional connectivities were associated with serum brain-derived neurotrophic factor (bdnf) levels and spatial expression of genes enriched in synaptic plasticity. |
2023-09-01 |
2023-09-07 |
Not clear |
| Valerio Ricci, Domenico de Berardis, Giovanni Martinotti, Giuseppe Main. Neurotrophic Factors In Cannabis-Induced Psychosis: An Update. Current topics in medicinal chemistry. 2023-08-30. PMID:37644743. |
in particular, nerve growth factor (ngf) plays an important role in the survival and function of cholinergic neurons while brain-derived neurotrophic factor (bdnf) is involved in synaptic plasticity and the maintenance of midbrain dopaminergic and cholinergic neurons. |
2023-08-30 |
2023-09-07 |
Not clear |
| Annela Avarlaid, Eli-Eelika Esvald, Indrek Koppel, Annabel Parkman, Anna Zhuravskaya, Eugene V Makeyev, Jürgen Tuvikene, Tõnis Timmus. An 840 kb distant upstream enhancer is a crucial regulator of catecholamine-dependent expression of the Bdnf gene in astrocytes. Glia. 2023-08-26. PMID:37632136. |
brain-derived neurotrophic factor (bdnf) plays a fundamental role in the developing and adult nervous system, contributing to neuronal survival, differentiation, and synaptic plasticity. |
2023-08-26 |
2023-09-07 |
Not clear |
| Simone Tambaro, Sumonto Mitra, Ruchi Gera, Bengt Linderoth, Lars U Wahlberg, Taher Darreh-Shori, Homira Behbahani, Per Nilsson, Maria Eriksdotte. Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to App Alzheimer's research & therapy. vol 15. issue 1. 2023-08-21. PMID:37596686. |
brain-derived neurotrophic factor (bdnf) is a key neurotrophin involved in the learning and memory process, with a crucial role in synaptic plasticity and neuronal survival. |
2023-08-21 |
2023-09-07 |
mouse |
| Hamed Alizadeh Pahlavan. Exercise therapy to prevent and treat Alzheimer's disease. Frontiers in aging neuroscience. vol 15. 2023-08-21. PMID:37600508. |
aerobic exercise significantly increases plasma levels of bdnf, nerve growth factor, synaptic plasticity, motor activity, spatial memory, and exploratory behavior in ad subjects. |
2023-08-21 |
2023-09-07 |
human |
| Hong Su, Haiyan Chen, Xi Zhang, Shengyong Su, Jing Li, Yanjun Guo, Qiongxiao Wang, Caiyun Xie, Pu Yan. Electroacupuncture ameliorates pain in cervical spondylotic radiculopathy rat by inhibiting the CaMKII/CREB/BDNF signaling pathway and regulating spinal synaptic plasticity. Brain and behavior. 2023-08-07. PMID:37548586. |
recent studies have shown that the calmodulin-dependent protein kinase ii (camkii)/camp-response element binding protein (creb)/brain-derived neurotrophic factor (bdnf) signaling pathway mediates central sensitization through its involvement in spinal cord synaptic plasticity. |
2023-08-07 |
2023-08-14 |
rat |
| Lv-Ping Zhuang, Wei-Jie Gao, Liu-Lv Fang, Gui-Rong Zeng, Qin-Yong Ye, Xiao-Man Dai, Jing Zhang, Xiao-Chun Che. HnRNPK is involved in stress-induced depression-like behavior via ERK-BDNF pathway in mice. Neurochemistry international. 2023-08-05. PMID:37543308. |
available literature indicates that it can regulate dendritic spine density through the extracellular signal-regulating kinase (erk) - brain-derived neurotrophic factor (bdnf) pathway, which is crucial to retain the synaptic plasticity in patients with major depressive disorder (mdd) and mouse depression models. |
2023-08-05 |
2023-08-14 |
mouse |
| Wanbing Wang, Yanzhong Li, Fangling Ma, Xuan Sheng, Kai Chen, Rengong Zhuo, Chen Wang, Honghua Zheng, Yun-Wu Zhang, Guojun Bu, Xiao-Fen Chen, Li Zhon. Microglial repopulation reverses cognitive and synaptic deficits in an Alzheimer's disease model by restoring BDNF signaling. Brain, behavior, and immunity. 2023-07-23. PMID:37482204. |
lastly, we demonstrated that the repopulation restores the expression of brain-derived neurotrophic factor (bdnf) in microglia, thereby contributing to synaptic plasticity. |
2023-07-23 |
2023-08-14 |
mouse |