| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suxin You, Zhouyun Ma, Pei Zhang, Wenwen Xu, Changsen Zhan, Nina Sang, Jiazhen Xu, Feiyun Wang, Jiange Zhan. Neuroprotective effects of the salidroside derivative SHPL-49 via the BDNF/TrkB/Gap43 pathway in rats with cerebral ischemia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 174. 2024-03-23. PMID:38520864. |
shpl-49 enhanced synaptic plasticity and increased gap43 protein levels via activation of the bdnf pathway in the ogd primary neuron model. |
2024-03-23 |
2024-03-26 |
rat |
| Igor Henrique Rodrigues de Paiva, Laís Macedo Maciel, Rodrigo Soares da Silva, Ingrid Prata Mendonça, José Roberto Botelho de Souza, Christina Alves Peixot. Prebiotics modulate the microbiota-gut-brain axis and ameliorate anxiety and depression-like behavior in HFD-fed mice. Food research international (Ottawa, Ont.). vol 182. 2024-03-22. PMID:38519181. |
additionally, markers of neurogenesis and synaptic plasticity, such as psd, sap 102, creb-p, and bdnf, were lower. |
2024-03-22 |
2024-03-25 |
mouse |
| Roberto Bonanni, Ida Cariati, Anna Maria Rinaldi, Mario Marini, Giovanna D'Arcangelo, Umberto Tarantino, Virginia Tancred. Trolox and recombinant Irisin as a potential strategy to prevent neuronal damage induced by random positioning machine exposure in differentiated HT22 cells. PloS one. vol 19. issue 3. 2024-03-21. PMID:38512830. |
particularly, we investigated cell viability by mts assay, trypan blue staining and western blotting analysis for akt and b-cell lymphoma 2 (bcl-2), the intracellular increase of reactive oxygen species (ros) by fluorescent probe and nadph oxidase 4 (nox4) expression, as well as the expression of brain-derived neurotrophic factor (bdnf), a major neurotrophin responsible for neurogenesis and synaptic plasticity. |
2024-03-21 |
2024-03-24 |
Not clear |
| Mehar Naseem, Hiba Khan, Suhel Parve. TrkB-BDNF Signalling and Arc/Arg3.1 Immediate Early Genes in the Anterior Cingulate Cortex and Hippocampus: Insights into Novel Memory Milestones Through Behavioural Tagging. Molecular neurobiology. 2024-03-15. PMID:38485841. |
brain-derived neurotrophic factor (bdnf) stands as a pivotal plasticity-related protein (prp) in mediating molecular alterations crucial for long-term synaptic plasticity and memory consolidation. |
2024-03-15 |
2024-03-17 |
rat |
| Giorgia Bimbi, Enrico Tongiorg. Chemical LTP induces confinement of BDNF mRNA under dendritic spines and BDNF protein accumulation inside the spines. Frontiers in molecular neuroscience. vol 17. 2024-03-07. PMID:38450041. |
the neurotrophin brain-derived neurotrophic factor (bdnf) plays a key role in neuronal development and synaptic plasticity. |
2024-03-07 |
2024-03-09 |
Not clear |
| Kensuke Nakajima, Ahreum Han, Arisa Kayano, Shigeru Ois. Upregulation Effect of Citrus Species on Brain-Derived Neurotrophic Factor. Journal of nutritional science and vitaminology. vol 70. issue 1. 2024-02-28. PMID:38417853. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that plays fundamental roles in neuronal survival and synaptic plasticity. |
2024-02-28 |
2024-03-02 |
human |
| Jiale Gao, Mingjiang Yao, Yehao Zhang, Yunyao Jiang, Jianxun Li. Panax notoginseng saponins stimulates the differentiation and neurite development of C17.2 neural stem cells against OGD/R injuries via mTOR signaling. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-21. PMID:38382327. |
moreover, pns enhanced the differentiation of c17.2 cells into neurons and astrocytes, and further promoted synaptic plasticity by significantly increasing the expressions of synapse-related proteins bdnf, syp and psd95. |
2024-02-21 |
2024-02-24 |
mouse |
| Svitlana V Bach, Allison J Bauman, Darya Hosein, Jennifer J Tuscher, Lara Ianov, Kelsey M Greathouse, Benjamin W Henderson, Jeremy H Herskowitz, Keri Martinowich, Jeremy J Da. Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons. Hippocampus. 2024-02-16. PMID:38362938. |
brain-derived neurotrophic factor (bdnf) plays a critical role in brain development, dendritic growth, synaptic plasticity, as well as learning and memory. |
2024-02-16 |
2024-02-18 |
rat |
| Jacopo Di Lucente, Giuseppe Persico, Zeyu Zhou, Lee-Way Jin, Jon J Ramsey, Jennifer M Rutkowsky, Claire M Montgomery, Alexey Tomilov, Kyoungmi Kim, Marco Giorgio, Izumi Maezawa, Gino A Cortopass. Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer's mouse model and stimulates synaptic plasticity pathway enzymes. Communications biology. vol 7. issue 1. 2024-02-16. PMID:38366025. |
kd induced significant increases in synaptic plasticity enzymes p-erk and p-creb in both sexes, and of brain-derived neurotrophic factor (bdnf) in app/ps1 females. |
2024-02-16 |
2024-02-19 |
mouse |
| Jie Wan, Linhui Ma, Xinhao Jiao, Wei Dong, Jiatao Lin, Yongkang Qiu, Weifeng Wu, Qiang Liu, Chen Chen, He Huang, Shuai Li, Hui Zheng, Yuqing W. Impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by BDNF downregulation contribute to cognitive dysfunction in mice induced by repeated neonatal exposure to ketamine. CNS neuroscience & therapeutics. vol 30. issue 2. 2024-02-09. PMID:38332635. |
impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by bdnf downregulation contribute to cognitive dysfunction in mice induced by repeated neonatal exposure to ketamine. |
2024-02-09 |
2024-02-11 |
mouse |
| Fatma Nada Khalifa, Riham F Hussein, Dina M Mekawy, Heba M Elwi, Shimaa Ahmed Alsaeed, Yassmin Elnawawy, Somaya H Shahee. Potential role of the lncRNA "HOTAIR"/miRNA "206"/BDNF network in the alteration in expression of synaptic plasticity gene arc and BDNF level in sera of patients with heroin use disorder through the PI3K/AKT/mTOR pathway compared to the controls. Molecular biology reports. vol 51. issue 1. 2024-02-09. PMID:38334898. |
potential role of the lncrna "hotair"/mirna "206"/bdnf network in the alteration in expression of synaptic plasticity gene arc and bdnf level in sera of patients with heroin use disorder through the pi3k/akt/mtor pathway compared to the controls. |
2024-02-09 |
2024-02-11 |
Not clear |
| Naomi Lomeli, Diana C Pearre, Maureen Cruz, Kaijun Di, Joni L Ricks-Oddie, Daniela A Bot. Cisplatin induces BDNF downregulation in middle-aged female rat model while BDNF enhancement attenuates cisplatin neurotoxicity. Experimental neurology. 2024-02-09. PMID:38336286. |
in conclusion, we established the first middle-aged rat model of cisplatin-induced crci, assessing the contribution of medical stress and longitudinal changes in bdnf levels with cognitive function, although future studies are warranted to assess the efficacy of bdnf enhancement in vivo on synaptic plasticity. |
2024-02-09 |
2024-02-12 |
rat |
| Judit Català-Solsona, Stefano Lutzu, Pablo J Lituma, Cristina Fábregas-Ordoñez, Dolores Siedlecki, Lydia Giménez-Llort, Alfredo J Miñano-Molina, Carlos A Saura, Pablo E Castillo, José Rodriguez-Álvare. Nr4a2 blocks oAβ-mediated synaptic plasticity dysfunction and ameliorates spatial memory deficits in the APP bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328087. |
recently, it has been reported that nr4a2, a member of the nr4a family of orphan nuclear receptors, plays a role in hippocampal synaptic plasticity by regulating bdnf and synaptic ampa receptors. |
2024-02-08 |
2024-02-10 |
mouse |
| J Solich, M Kolasa, A Faron-Górecka, P Pabian, K Latocha, A Korlatowicz, M Dziedzicka-Wasylewsk. Modulating Stress Susceptibility and Resilience: Insights from miRNA Manipulation and Neural Mechanisms in Mice. Molecular neurobiology. 2024-01-27. PMID:38280111. |
the expression changes of genes such as dgkq, bdnf, ntrk2, and pde4b in the mouse cerebellum suggested a link between cerebellar function, synaptic plasticity, and the differential stress responses observed in susceptible and resilient mice. |
2024-01-27 |
2024-01-30 |
mouse |
| Fatemeh Nikpour, Amir Salimi, Amene Saghazadeh, Nima Rezae. Blood and CSF levels of brain-derived neurotrophic factor in patients with encephalopathy/encephalitis: a systematic review and meta-analysis. Acta neurologica Belgica. 2024-01-24. PMID:38267724. |
brain-derived neurotrophic factor (bdnf) is critical for enhancing the survival and growth of neurons and modulating the synaptic plasticity. |
2024-01-24 |
2024-01-27 |
Not clear |
| Hideo Takekoshi, Masaki Fujishima, Taiki Miyazawa, Ohki Higuchi, Takahiko Fujikawa, Teruo Miyazaw. Simultaneous Intake of Chlorella and Ascidian Ethanolamine Plasmalogen Accelerates Activation of BDNF-TrkB-CREB Signaling in Rats. Molecules (Basel, Switzerland). vol 29. issue 2. 2024-01-23. PMID:38257270. |
brain-derived neurotrophic factor (bdnf) plays an important role in neurogenesis, synaptic plasticity, and cognition. |
2024-01-23 |
2024-01-25 |
human |
| Zhenlong Li, Chau-Shoun Lee, Si Chen, Benyu He, Xinya Chen, Hsien-Yu Peng, Tzer-Bin Lin, Ming-Chun Hsieh, Cheng-Yuan Lai, Dylan Cho. Blue light at night produces stress-evoked heightened aggression by enhancing brain-derived neurotrophic factor in the basolateral amygdala. Neurobiology of stress. vol 28. 2024-01-08. PMID:38187456. |
collectively, these results suggest that blan results in stress-evoked heightened aggressive phenotypes, which may work by enhancing bla bdnf signaling and synaptic plasticity. |
2024-01-08 |
2024-01-10 |
rat |
| Md Anisuzzaman Chowdhury, Jessica M Collins, David A Gell, Sharn Perry, Michael C Breadmore, Sarah Shigdar, Anna E Kin. Isolation and Identification of the High-Affinity DNA Aptamer Target to the Brain-Derived Neurotrophic Factor (BDNF). ACS chemical neuroscience. 2023-12-27. PMID:38149631. |
bdnf is a potential biomarker of brain health and neurodegenerative diseases and has functions in the synaptic plasticity and survival of neurons. |
2023-12-27 |
2023-12-29 |
Not clear |
| Cristina Lao-Peregrin, Guoqing Xiang, Jihye Kim, Ipsit Srivastava, Alexandra B Fall, Danielle M Gerhard, Piia Kohtala, Daegeon Kim, Minseok Song, Mikel Garcia-Marcos, Joshua Levitz, Francis S Le. Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk. Cell reports. vol 43. issue 1. 2023-12-20. PMID:38117654. |
we find that the receptor tyrosine kinase (rtk) trkb and the g-protein-coupled receptor (gpcr) metabotropic glutamate receptor 5 (mglur5) together mediate hippocampal synaptic plasticity in response to brain-derived neurotrophic factor (bdnf). |
2023-12-20 |
2023-12-23 |
Not clear |
| Marta Ditmer, Agata Gabryelska, Szymon Turkiewicz, Marcin Socha. Investigating the Role of BDNF in Insomnia: Current Insights. Nature and science of sleep. vol 15. 2023-12-13. PMID:38090631. |
bdnf is a neurotrophin primarily responsible for synaptic plasticity and proper functioning of neurons. |
2023-12-13 |
2023-12-17 |
Not clear |