| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Danbi Jo, Seo Yeon Ahn, Seo Yoon Choi, Yoonjoo Choi, Dong Hoon Lee, Juhyun Son. Positive Effects of Adiponectin, BDNF, and GLP-1 on Cortical Neurons Counteracting Palmitic Acid Induced Neurotoxicity. Clinical nutrition research. vol 13. issue 2. 2024-05-24. PMID:38784850. |
our findings demonstrate the therapeutic potential of adiponectin, bdnf, and glp-1 in enhancing synaptic plasticity within brains affected by metabolic imbalance. |
2024-05-24 |
2024-05-27 |
Not clear |
| Zhenhuan Wang, Qi Hu, Chao Tian, Ruipeng Wang, Qingyan Jiao, Feng Chen, Tongrui Wu, Jialiang Wang, Yuxuan Zhu, Aili Liu, Wei Zhang, Jie Li, Hui She. Prophylactic Effects of n-Acethylcysteine on Inflammation-induced Depression-like Behaviors in Mice. Neuroscience. 2024-05-16. PMID:38729599. |
this study sought to determine whether nac use could mitigate inflammatory depressive behavior through the enhancement of synaptic transmission, synaptic plasticity, and increasing levels of brain-derived neurotrophic factor (bdnf). |
2024-05-16 |
2024-05-27 |
mouse |
| Carmen Almodóvar-Payá, Maria Guardiola-Ripoll, Maria Giralt-López, Maitane Oscoz-Irurozqui, Erick Jorge Canales-Rodríguez, Mercè Madre, Joan Soler-Vidal, Núria Ramiro, Luis F Callado, Bárbara Arias, Carme Gallego, Edith Pomarol-Clotet, Mar Fatjó-Vila. NRN1 epistasis with BDNF and CACNA1C: mediation effects on symptom severity through neuroanatomical changes in schizophrenia. Brain structure & function. 2024-05-08. PMID:38720004. |
the expression of neuritin-1 (nrn1), a neurotrophic factor crucial for neurodevelopment and synaptic plasticity, is enhanced by the brain derived neurotrophic factor (bdnf). |
2024-05-08 |
2024-05-27 |
human |
| Tareq I Jibril, Karem H Alzoubi, Nizar M Mhaidat, Omar F Khabour, Mohammad A Y Alqudah, Abeer M Rababa'h, Nasr Alrabadi, Doaa Al-Udat. Sildenafil prevents chronic psychosocial stress-induced working memory impairment: Role of brain-derived neurotrophic factor. Current research in pharmacology and drug discovery. vol 6. 2024-05-06. PMID:38706525. |
reduced brain-derived neurotrophic factor (bdnf) levels, increased oxidative stress, and alteration of synaptic plasticity biomarkers are also possible contributors to the negative impact of stress on learning and memory. |
2024-05-06 |
2024-05-08 |
rat |
| Jiena Hong, Jiemei Chen, Chao Li, Fei Zhao, Jiantao Zhang, Yilong Shan, Hongmei We. High-frequency rTMS alleviates cognitive impairment and regulates synaptic plasticity in the hippocampus of rats with cerebral ischemia. Behavioural brain research. vol 467. 2024-04-28. PMID:38678971. |
the underlying mechanism might be modulating the synaptic plasticity and up-regulating the expression psd95, syn, and bdnf in the hippocampus. |
2024-04-28 |
2024-05-01 |
rat |
| Theresa Harvey, Maribel Rio. The Role of BDNF and TrkB in the Central Control of Energy and Glucose Balance: An Update. Biomolecules. vol 14. issue 4. 2024-04-27. PMID:38672441. |
bdnf is a highly conserved neurotrophin that signals via the tropomyosin-related kinase b (trkb) receptor to facilitate neuronal survival, differentiation, and synaptic plasticity and function. |
2024-04-27 |
2024-04-29 |
Not clear |
| Guillermo Moya-Alvarado, Xavier Valero-Peña, Alejandro Aguirre-Soto, Fernando J Bustos, Oscar M Lazo, Francisca C Bronfma. PLC-γ-Ca Frontiers in molecular neuroscience. vol 17. 2024-04-26. PMID:38660384. |
the binding of bdnf to trkb triggers the activation of different signaling pathways, including the erk, plc-γ and pi3k-mtor pathways, to induce dendritic growth and synaptic plasticity. |
2024-04-26 |
2024-04-28 |
Not clear |
| Alexandros Tsimpolis, Konstantinos Kalafatakis, Ioannis Charalampopoulo. Recent advances in the crosstalk between the brain-derived neurotrophic factor and glucocorticoids. Frontiers in endocrinology. vol 15. 2024-04-22. PMID:38645426. |
brain-derived neurotrophic factor (bdnf), a key neurotrophin within the brain, by selectively activating the trkb receptor, exerts multimodal effects on neurodevelopment, synaptic plasticity, cellular integrity and neural network dynamics. |
2024-04-22 |
2024-04-24 |
Not clear |
| Rafael Penadés, Carmen Almodóvar-Payá, Clemente García-Rizo, Victoria Ruíz, Rosa Catalán, Sergi Valero, Til Wykes, Mar Fatjó-Vilas, Bárbara Aria. Changes in BDNF methylation patterns after cognitive remediation therapy in schizophrenia: A randomized and controlled trial. Journal of psychiatric research. vol 173. 2024-03-27. PMID:38537483. |
a gene central to synaptic plasticity, the bdnf, has been proposed as one potential route. |
2024-03-27 |
2024-03-30 |
human |
| Suxin You, Zhouyun Ma, Pei Zhang, Wenwen Xu, Changsen Zhan, Nina Sang, Jiazhen Xu, Feiyun Wang, Jiange Zhan. Neuroprotective effects of the salidroside derivative SHPL-49 via the BDNF/TrkB/Gap43 pathway in rats with cerebral ischemia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 174. 2024-03-23. PMID:38520864. |
shpl-49 enhanced synaptic plasticity and increased gap43 protein levels via activation of the bdnf pathway in the ogd primary neuron model. |
2024-03-23 |
2024-03-26 |
rat |
| Igor Henrique Rodrigues de Paiva, Laís Macedo Maciel, Rodrigo Soares da Silva, Ingrid Prata Mendonça, José Roberto Botelho de Souza, Christina Alves Peixot. Prebiotics modulate the microbiota-gut-brain axis and ameliorate anxiety and depression-like behavior in HFD-fed mice. Food research international (Ottawa, Ont.). vol 182. 2024-03-22. PMID:38519181. |
additionally, markers of neurogenesis and synaptic plasticity, such as psd, sap 102, creb-p, and bdnf, were lower. |
2024-03-22 |
2024-03-25 |
mouse |
| Roberto Bonanni, Ida Cariati, Anna Maria Rinaldi, Mario Marini, Giovanna D'Arcangelo, Umberto Tarantino, Virginia Tancred. Trolox and recombinant Irisin as a potential strategy to prevent neuronal damage induced by random positioning machine exposure in differentiated HT22 cells. PloS one. vol 19. issue 3. 2024-03-21. PMID:38512830. |
particularly, we investigated cell viability by mts assay, trypan blue staining and western blotting analysis for akt and b-cell lymphoma 2 (bcl-2), the intracellular increase of reactive oxygen species (ros) by fluorescent probe and nadph oxidase 4 (nox4) expression, as well as the expression of brain-derived neurotrophic factor (bdnf), a major neurotrophin responsible for neurogenesis and synaptic plasticity. |
2024-03-21 |
2024-03-24 |
Not clear |
| Mehar Naseem, Hiba Khan, Suhel Parve. TrkB-BDNF Signalling and Arc/Arg3.1 Immediate Early Genes in the Anterior Cingulate Cortex and Hippocampus: Insights into Novel Memory Milestones Through Behavioural Tagging. Molecular neurobiology. 2024-03-15. PMID:38485841. |
brain-derived neurotrophic factor (bdnf) stands as a pivotal plasticity-related protein (prp) in mediating molecular alterations crucial for long-term synaptic plasticity and memory consolidation. |
2024-03-15 |
2024-03-17 |
rat |
| Giorgia Bimbi, Enrico Tongiorg. Chemical LTP induces confinement of BDNF mRNA under dendritic spines and BDNF protein accumulation inside the spines. Frontiers in molecular neuroscience. vol 17. 2024-03-07. PMID:38450041. |
the neurotrophin brain-derived neurotrophic factor (bdnf) plays a key role in neuronal development and synaptic plasticity. |
2024-03-07 |
2024-03-09 |
Not clear |
| Kensuke Nakajima, Ahreum Han, Arisa Kayano, Shigeru Ois. Upregulation Effect of Citrus Species on Brain-Derived Neurotrophic Factor. Journal of nutritional science and vitaminology. vol 70. issue 1. 2024-02-28. PMID:38417853. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that plays fundamental roles in neuronal survival and synaptic plasticity. |
2024-02-28 |
2024-03-02 |
human |
| Jiale Gao, Mingjiang Yao, Yehao Zhang, Yunyao Jiang, Jianxun Li. Panax notoginseng saponins stimulates the differentiation and neurite development of C17.2 neural stem cells against OGD/R injuries via mTOR signaling. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-21. PMID:38382327. |
moreover, pns enhanced the differentiation of c17.2 cells into neurons and astrocytes, and further promoted synaptic plasticity by significantly increasing the expressions of synapse-related proteins bdnf, syp and psd95. |
2024-02-21 |
2024-02-24 |
mouse |
| Svitlana V Bach, Allison J Bauman, Darya Hosein, Jennifer J Tuscher, Lara Ianov, Kelsey M Greathouse, Benjamin W Henderson, Jeremy H Herskowitz, Keri Martinowich, Jeremy J Da. Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons. Hippocampus. 2024-02-16. PMID:38362938. |
brain-derived neurotrophic factor (bdnf) plays a critical role in brain development, dendritic growth, synaptic plasticity, as well as learning and memory. |
2024-02-16 |
2024-02-18 |
rat |
| Jacopo Di Lucente, Giuseppe Persico, Zeyu Zhou, Lee-Way Jin, Jon J Ramsey, Jennifer M Rutkowsky, Claire M Montgomery, Alexey Tomilov, Kyoungmi Kim, Marco Giorgio, Izumi Maezawa, Gino A Cortopass. Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer's mouse model and stimulates synaptic plasticity pathway enzymes. Communications biology. vol 7. issue 1. 2024-02-16. PMID:38366025. |
kd induced significant increases in synaptic plasticity enzymes p-erk and p-creb in both sexes, and of brain-derived neurotrophic factor (bdnf) in app/ps1 females. |
2024-02-16 |
2024-02-19 |
mouse |
| Jie Wan, Linhui Ma, Xinhao Jiao, Wei Dong, Jiatao Lin, Yongkang Qiu, Weifeng Wu, Qiang Liu, Chen Chen, He Huang, Shuai Li, Hui Zheng, Yuqing W. Impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by BDNF downregulation contribute to cognitive dysfunction in mice induced by repeated neonatal exposure to ketamine. CNS neuroscience & therapeutics. vol 30. issue 2. 2024-02-09. PMID:38332635. |
impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by bdnf downregulation contribute to cognitive dysfunction in mice induced by repeated neonatal exposure to ketamine. |
2024-02-09 |
2024-02-11 |
mouse |
| Fatma Nada Khalifa, Riham F Hussein, Dina M Mekawy, Heba M Elwi, Shimaa Ahmed Alsaeed, Yassmin Elnawawy, Somaya H Shahee. Potential role of the lncRNA "HOTAIR"/miRNA "206"/BDNF network in the alteration in expression of synaptic plasticity gene arc and BDNF level in sera of patients with heroin use disorder through the PI3K/AKT/mTOR pathway compared to the controls. Molecular biology reports. vol 51. issue 1. 2024-02-09. PMID:38334898. |
potential role of the lncrna "hotair"/mirna "206"/bdnf network in the alteration in expression of synaptic plasticity gene arc and bdnf level in sera of patients with heroin use disorder through the pi3k/akt/mtor pathway compared to the controls. |
2024-02-09 |
2024-02-11 |
Not clear |