| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mayuri N Tuwar, Wei-Hung Chen, Arthur M Chiwaya, Hsu-Ling Yeh, Minh H Nguyen, Chyi-Huey Ba. Brain-Derived Neurotrophic Factor (BDNF) and Translocator Protein (TSPO) as Diagnostic Biomarkers for Acute Ischemic Stroke. Diagnostics (Basel, Switzerland). vol 13. issue 13. 2023-07-14. PMID:37443691. |
brain-derived neurotrophic factor (bdnf) interacts with tropomyosin-related kinase b (trkb) to promote neuronal growth, survival, differentiation, neurotransmitter release, and synaptic plasticity. |
2023-07-14 |
2023-08-14 |
Not clear |
| Beatriz Benítez-Temiño, Rosendo G Hernández, Rosa R de la Cruz, Angel M Pasto. BDNF Influence on Adult Terminal Axon Sprouting after Partial Deafferentation. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445838. |
bdnf is a neurotrophin family member implicated in many different neuronal functions, from neuronal survival during development to synaptic plasticity associated with processes of learning and memory. |
2023-07-14 |
2023-08-14 |
Not clear |
| Igor Henrique Rodrigues de Paiva, Rodrigo Soares da Silva, Ingrid Prata Mendonça, Eduardo Duarte-Silva, José Roberto Botelho de Souza, Christina Alves Peixot. Fructooligosaccharide (FOS) and Galactooligosaccharide (GOS) Improve Neuroinflammation and Cognition By Up-regulating IRS/PI3K/AKT Signaling Pathway in Diet-induced Obese Mice. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023-06-29. PMID:37382830. |
these obese mice also showed activation of microglia and astrocytes and significant immunoreactivity of neuroinflammatory and apoptosis markers, such as tnf-α, cox-2, and caspase-3, in addition to lower expression of neurogenesis and synaptic plasticity markers, such as neun, ki-67, creb-p, and bdnf. |
2023-06-29 |
2023-08-14 |
mouse |
| Igor Henrique Rodrigues de Paiva, Rodrigo Soares da Silva, Ingrid Prata Mendonça, Eduardo Duarte-Silva, José Roberto Botelho de Souza, Christina Alves Peixot. Fructooligosaccharide (FOS) and Galactooligosaccharide (GOS) Improve Neuroinflammation and Cognition By Up-regulating IRS/PI3K/AKT Signaling Pathway in Diet-induced Obese Mice. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023-06-29. PMID:37382830. |
in addition, fos and gos promoted synaptic plasticity by increasing neun, p-creb, bdnf, and ki-67, restoring spatial learning ability and memory. |
2023-06-29 |
2023-08-14 |
mouse |
| Jingyuan Ma, Feng Xiong, Zhouru Li, Guokai Dong, Xiaoming Sun, Wenjiang Yin, Hongxing Ca. The effect of chronic alcohol exposure on spatial memory and BDNF-TrkB- PLCγ1 signaling in the hippocampus of male and female mice. Heliyon. vol 9. issue 6. 2023-06-12. PMID:37303582. |
given previously known effects of brain-derived neurotrophic factor (bdnf) in regulating synaptic plasticity and learning and memory, we investigated the effect of chronic alcohol consumption on spatial memory impairment in both sexes and changes in bdnf signaling in the hippocampus. |
2023-06-12 |
2023-08-14 |
mouse |
| Ram Kumar Manthari, Prathyusha Koyya, Santhi Latha Pandrang. Brain-Derived Neurotrophic Factor - The Protective Agent Against Neurological Disorders. CNS & neurological disorders drug targets. 2023-06-08. PMID:37287291. |
one among them is the brain-derived neurotrophic factor (bdnf), which performs several vital functions, enhancing synaptic plasticity and assisting in the emergence of long-term thoughts. |
2023-06-08 |
2023-08-14 |
Not clear |
| Shiji Zhang, Weng Fu, Xiaoe Jia, Rengui Bade, Xiaolei Liu, Yabin Xie, Wei Xie, Shuyuan Jiang, Guo Sha. Hypoxic Preconditioning Modulates BDNF and Its Signaling through DNA Methylation to Promote Learning and Memory in Mice. ACS chemical neuroscience. 2023-06-08. PMID:37289948. |
brain-derived neurotrophic factor (bdnf) activates its signaling upon binding to the tropomyosin-related kinase b (trkb) receptor, which is involved in neuronal growth, differentiation, and synaptic plasticity. |
2023-06-08 |
2023-08-14 |
mouse |
| Pavan Thapak, Gregory Smith, Zhe Ying, Afshin Paydar, Neil Harris, Fernando Gomez-Pinill. The BDNF mimetic R-13 attenuates TBI pathogenesis using TrkB-related pathways and bioenergetics. Biochimica et biophysica acta. Molecular basis of disease. 2023-06-07. PMID:37286142. |
additionally, r13 was found to counteract reductions in molecules associated with bdnf signaling (p-trkb, p-pi3k, p-akt), synaptic plasticity (glur2, psd95, synapsin i) as well as bioenergetic components such as mitophagy (sod, pgc-1α, pink1, parkin, bnip3, and lc3) and real-time mitochondrial respiratory capacity. |
2023-06-07 |
2023-08-14 |
Not clear |
| Bradley John Baranowski, Ahmad Mohammad, Michael S Finch, Alex Brown, Roopan Dhaliwal, Daniel M Marko, Paul J LeBlanc, Cheryl M McCormick, Val A Fajardo, Rebecca E K MacPherso. Exercise training and BDNF injections alter APP processing enzymes and improve cognition. Journal of applied physiology (Bethesda, Md. : 1985). 2023-06-01. PMID:37262102. |
bdnf is an exercise-induced neurotrophin known for its role in synaptic plasticity, neurite growth, and neuronal survival. |
2023-06-01 |
2023-08-14 |
Not clear |
| Zijuan Zhang, Ziyang Yu, Ye Yuan, Jing Yang, Shijie Wang, He Ma, Li Hao, Jinlian Ma, Zhonghua Li, Zhenqiang Zhang, Christian Hölsche. Cholecystokinin Signaling can Rescue Cognition and Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer's Disease. Molecular neurobiology. 2023-05-29. PMID:37247071. |
our study found that the cck analogue could effectively improve spatial learning and memory, enhance synaptic plasticity in the hippocampus, normalize synapse numbers and morphology and the levels of key synaptic proteins, up-regulate the pi3k/akt signaling pathway and normalize pka, creb, bdnf and trkb receptor levels in app/ps1 mice. |
2023-05-29 |
2023-08-14 |
mouse |
| Juan Carlos Arévalo, Rubén Deogracia. Mechanisms Controlling the Expression and Secretion of BDNF. Biomolecules. vol 13. issue 5. 2023-05-27. PMID:37238659. |
among them, bdnf plays a crucial role in the development and correct maintenance of brain circuits and synaptic plasticity as well as in neurodegenerative diseases. |
2023-05-27 |
2023-08-14 |
Not clear |
| Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xian. Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson's Disease. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175535. |
moreover, treadmill exercise enhanced the synaptic plasticity of hippocampal pyramidal neurons via increased dopamine levels and bdnf in the pd mice. |
2023-05-14 |
2023-08-14 |
mouse |
| Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xian. Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson's Disease. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175535. |
the direct protective effect of fndc5 is achieved by promoting the secretion of bdnf in the hippocampal neurons via binding the integrin αvβ5 receptor, thereby improving synaptic plasticity. |
2023-05-14 |
2023-08-14 |
mouse |
| Jing Wang, Jianxing Wang, Yulai Wang, Yiwen Chai, Haochen Li, Deyang Miao, Honggui Liu, Jianhong Li, Jun Ba. Music with Different Tones Affects the Development of Brain Nerves in Mice in Early Life through BDNF and Its Downstream Pathways. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175826. |
in addition, the number of dendritic spines and the number of dendritic spines per unit length were significantly higher than those in group c, and the expressions of synaptic plasticity proteins (syp and psd95) were also significantly elevated over those in group c. compared with group c, the expression levels of bdnf, trkb, creb, pi3k, akt, gs3kβ, plcγ1, pkc, dag, erk and mapk genes and proteins in the hippocampus and prefrontal cortex of mice in the music groups were up-regulated, suggesting that different tones of music could regulate neural development through bdnf and its downstream pathways. |
2023-05-14 |
2023-08-14 |
mouse |
| Ye Ji Lee, Ye Ji Jeong, Eun Ji Kang, Beom Seok Kang, Song Hee Lee, You Jin Kim, Seong Su Kang, Sang Won Suh, Eun Hee Ah. GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression. Frontiers in molecular neuroscience. vol 16. 2023-05-05. PMID:37143467. |
brain-derived neurotrophic factor (bdnf) is closely related to neurodegeneration and synaptic plasticity during the aging process. |
2023-05-05 |
2023-08-14 |
Not clear |
| Timothy C Durazzo, M Windy McNerney, Annika M Hansen, Meng Gu, Matthew D Sacchet, Claudia B Padul. BDNF rs6265 Met carriers with alcohol use disorder show greater age-related decline of N-acetylaspartate in left dorsolateral prefrontal cortex. Drug and alcohol dependence. vol 248. 2023-05-05. PMID:37146499. |
brain-derived neurotrophic factor (bdnf) is implicated in neuronal and glial cell growth and differentiation, synaptic plasticity, and apoptotic mechanisms. |
2023-05-05 |
2023-08-14 |
Not clear |
| Zhengyang Quan, Hui Li, Zhenzhen Quan, Hong Qin. Appropriate Macronutrients or Mineral Elements Are Beneficial to Improve Depression and Reduce the Risk of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108261. |
for example, excessive fat intake can lead to depression, with possible mechanisms including inflammation, increased oxidative stress, reduced synaptic plasticity, and decreased expression of 5-hydroxytryptamine (5-ht), brain derived neurotrophic factor (bdnf), postsynaptic density protein 95(psd-95), etc. |
2023-04-28 |
2023-08-14 |
Not clear |
| Anna Pisani, Fabiola Paciello, Valeria Del Vecchio, Rita Malesci, Eugenio De Corso, Elena Cantone, Anna Rita Feton. The Role of BDNF as a Biomarker in Cognitive and Sensory Neurodegeneration. Journal of personalized medicine. vol 13. issue 4. 2023-04-28. PMID:37109038. |
many studies have highlighted the protective effects of bdnf in the brain, showing how it can promote neuronal growth and survival and modulate synaptic plasticity. |
2023-04-28 |
2023-08-14 |
Not clear |
| Jing Fan, Dongmei Chen, Niannian Wang, Rui Su, Hao Li, Hailin Ma, Fei Ga. Negative relationship between brain-derived neurotrophic factor (BDNF) and attention: A possible elevation in BDNF level among high-altitude migrants. Frontiers in neurology. vol 14. 2023-04-28. PMID:37114226. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophic family that plays a vital role in regulating neuronal activity and synaptic plasticity in the brain, affects attention. |
2023-04-28 |
2023-08-14 |
Not clear |
| Songul Ozkula, Mahluga Jafarova Demirkapu, Hasan Raci Yananli, Banu Aydin, Cevdet Nacar, Hulya Cabada. The effect of acute topiramate administration on morphine withdrawal syndrome and brain-derived neurotrophic factor in central nervous system. Neurological research. 2023-04-27. PMID:37105528. |
brain-derived neurotrophic factor (bdnf), which plays a key role in synaptic plasticity, is produced from probdnf. |
2023-04-27 |
2023-08-14 |
Not clear |