| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Serena Camuso, Piergiorgio La Rosa, Maria Teresa Fiorenza, Sonia Canterin. Pleiotropic effects of BDNF on the cerebellum and hippocampus: Implications for neurodevelopmental disorders. Neurobiology of disease. 2022-01-02. PMID:34974125. |
brain-derived neurotrophic factor (bdnf) is one of the most studied neurotrophins in the mammalian brain, essential not only to the development of the central nervous system but also to synaptic plasticity. |
2022-01-02 |
2023-08-13 |
Not clear |
| Karin Seidler, Michelle Barro. Intermittent Fasting and Cognitive Performance - Targeting BDNF as Potential Strategy to Optimise Brain Health. Frontiers in neuroendocrinology. 2021-12-20. PMID:34929259. |
aging-related loss of bdnf has been associated with reduced synaptic plasticity, memory and learning as well as increased risk of cognitive impairment and alzheimer's disease. |
2021-12-20 |
2023-08-13 |
human |
| Waleska Maria Almeida Barros, Matheus Santos de Sousa Fernandes, Roberta Karlize Pereira Silva, Karollainy Gomes da Silva, Ana Patricia da Silva Souza, Mariluce Rodrigues Marques Silva, Ana Beatriz Januario da Silva, Gabriela Carvalho Jurema Santos, Maria Eduarda Rodrigues Alves Dos Santos, Taciane Silva do Carmo, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souz. Does the enriched environment alter memory capacity in malnourished rats by modulating BDNF expression? Journal of applied biomedicine. vol 19. issue 3. 2021-12-15. PMID:34907761. |
the bdnf may interfere in synaptic plasticity processes, such as memory. |
2021-12-15 |
2023-08-13 |
rat |
| Waleska Maria Almeida Barros, Matheus Santos de Sousa Fernandes, Roberta Karlize Pereira Silva, Karollainy Gomes da Silva, Ana Patricia da Silva Souza, Mariluce Rodrigues Marques Silva, Ana Beatriz Januario da Silva, Gabriela Carvalho Jurema Santos, Maria Eduarda Rodrigues Alves Dos Santos, Taciane Silva do Carmo, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souz. Does the enriched environment alter memory capacity in malnourished rats by modulating BDNF expression? Journal of applied biomedicine. vol 19. issue 3. 2021-12-15. PMID:34907761. |
thereby, evidence from the scientific literature suggests that the mechanisms of synaptic plasticity in the hippocampus of adult animals are influenced by malnutrition and ee, and these alterations may involve the participation of bdnf as a key regulator in memory processes in the adult animal hippocampus. |
2021-12-15 |
2023-08-13 |
rat |
| Debora Cutuli, Eugenia Landolfo, Laura Petrosini, Francesca Gelf. Environmental Enrichment Effects on the Brain-Derived Neurotrophic Factor Expression in Healthy Condition, Alzheimer's Disease, and Other Neurodegenerative Disorders. Journal of Alzheimer's disease : JAD. 2021-12-13. PMID:34897089. |
brain-derived neurotrophic factor (bdnf), a protein belonging to the neurotrophin family, is known to be heavily involved in synaptic plasticity processes that support brain development, post-lesion regeneration, and cognitive performances, such as learning and memory. |
2021-12-13 |
2023-08-13 |
Not clear |
| Ying Yu, Zhaokun Shi, Dan Xu, Ying Li, Jun Qin, Zhaohui Zhang, Hui Wan. Prenatal ethanol exposure increases susceptibility to depression- and anxiety-like behavior in adult female offspring and its underlying mechanism. Reproductive toxicology (Elmsford, N.Y.). vol 96. 2021-12-06. PMID:32497709. |
the latter inhibits the hippocampal bdnf pathway, leading to the disruption of hippocampal neurogenesis, apoptosis and decreased synaptic plasticity. |
2021-12-06 |
2023-08-13 |
rat |
| Wenya Pei, Fanqi Meng, Qingwen Deng, Baobao Zhang, Yuan Gu, Boyu Jiao, Haoyu Xu, Jiuqing Tan, Xin Zhou, Zhiling Li, Guanheng He, Jingwen Ruan, Ying Din. Electroacupuncture promotes the survival and synaptic plasticity of hippocampal neurons and improvement of sleep deprivation-induced spatial memory impairment. CNS neuroscience & therapeutics. vol 27. issue 12. 2021-12-01. PMID:34623740. |
this study aimed to investigate whether electroacupuncture (ea) promotes the survival and synaptic plasticity of hippocampal neurons by activating brain-derived neurotrophic factor (bdnf)/tyrosine receptor kinase (trkb)/extracellular signal-regulated kinase (erk) signaling, thereby improving spatial memory deficits in rats under sd. |
2021-12-01 |
2023-08-13 |
rat |
| Chih-Ming Cheng, Chen-Jee Hong, Hui-Ching Lin, Po-Jui Chu, Mu-Hong Chen, Pei-Chi Tu, Ya-Mei Bai, Wen-Han Chang, Chi-Hung Juan, Wei-Chen Lin, Shih-Jen Tsai, Tung-Ping Su, Cheng-Ta L. Predictive roles of brain-derived neurotrophic factor Val66Met polymorphism on antidepressant efficacy of different forms of prefrontal brain stimulation monotherapy: A randomized, double-blind, sham-controlled study. Journal of affective disorders. vol 297. 2021-11-29. PMID:34715162. |
although repetitive transcranial magnetic stimulation (rtms) and prolonged intermittent theta-burst stimulation (pitbs) can induce changes in synaptic plasticity, the influence of brain-derived neurotrophic factor (bdnf) genotypes on their antidepressant effects remain unknown. |
2021-11-29 |
2023-08-13 |
Not clear |
| Joyce Keife. Comparative Genomics of the BDNF Gene, Non-Canonical Modes of Transcriptional Regulation, and Neurological Disease. Molecular neurobiology. vol 58. issue 6. 2021-11-24. PMID:33517560. |
bdnf is a neurotrophin whose expression is essential for cellular growth, synaptogenesis, and synaptic plasticity. |
2021-11-24 |
2023-08-13 |
Not clear |
| Sahabuddin Ahmed, Mohit Kwatra, Basveshwar Gawali, Samir Ranjan Panda, V G M Naid. Potential role of TrkB agonist in neuronal survival by promoting CREB/BDNF and PI3K/Akt signaling in vitro and in vivo model of 3-nitropropionic acid (3-NP)-induced neuronal death. Apoptosis : an international journal on programmed cell death. vol 26. issue 1-2. 2021-11-22. PMID:33226552. |
striatal neurons depends on an afferent supply of brain-derived neurotrophic factor-(bdnf) that explicitly interacts with tropomyosin receptor kinase b (trkb) receptor and performs sundry functions including synaptic plasticity, neuronal differentiation and growth. |
2021-11-22 |
2023-08-13 |
mouse |
| Zhaoqing Zheng, Joyce Keife. Learning-Dependent Transcriptional Regulation of BDNF by its Truncated Protein Isoform in Turtle. Journal of molecular neuroscience : MN. vol 71. issue 5. 2021-11-19. PMID:33025480. |
the vertebrate brain-derived neurotrophic factor (bdnf) gene produces a number of alternatively spliced transcripts only some of which generate the bdnf protein required for synaptic plasticity and learning. |
2021-11-19 |
2023-08-13 |
Not clear |
| Wei Wei, Qiuying Dong, Wenbo Jiang, Yue Wang, Yingying Chen, Tianshu Han, Changhao Su. Dichloroacetic acid-induced dysfunction in rat hippocampus and the protective effect of curcumin. Metabolic brain disease. vol 36. issue 4. 2021-11-12. PMID:33411217. |
conversely, various doses of curcumin attenuated dcaa-induced oxidative stress, inflammation response and impaired synaptic plasticity, while elevating camp, pka, p-creb, bdnf, psd-95, syp levels. |
2021-11-12 |
2023-08-13 |
rat |
| Madhuparna Banerjee, Rekha R Sheno. Emphasizing roles of BDNF promoters and inducers in Alzheimer's disease for improving impaired cognition and memory. Journal of basic and clinical physiology and pharmacology. 2021-11-09. PMID:34751526. |
in alzheimer's disease (ad), often it is seen that low levels of bdnf are present, which primarily contributes to cognition deficit by regulating long-term potentiation (ltp) and synaptic plasticity. |
2021-11-09 |
2023-08-13 |
Not clear |
| L F Zainullina, Yu V Vakhitova, A Yu Lusta, T A Gudasheva, S B Seredeni. Dimeric mimetic of BDNF loop 4 promotes survival of serum-deprived cell through TrkB-dependent apoptosis suppression. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:33833366. |
brain-derived neurotrophic factor (bdnf) is involved in the regulation of neuronal cell growth, differentiation, neuroprotection and synaptic plasticity. |
2021-11-08 |
2023-08-13 |
Not clear |
| Zhenzhen Chen, Zhenyu Tang, Ke Zou, Zhihong Huang, Liuer Liu, Yuanjian Yang, Wei Wan. D-Serine produces antidepressant-like effects in mice through suppression of BDNF signaling pathway and regulation of synaptic adaptations in the nucleus accumbens. Molecular medicine (Cambridge, Mass.). vol 27. issue 1. 2021-11-08. PMID:34654365. |
d-serine is a crucial endogenous co-agonist of n-methyl-d-aspartate receptors (nmdars) in the central nervous system and can affect the function of the brain derived neurotrophic factor (bdnf) system, which plays an essential role in modulating synaptic plasticity. |
2021-11-08 |
2023-08-13 |
mouse |
| Sneha Sagarkar, Amit G Choudhary, Nagalakshmi Balasubramanian, Sanjay N Awathale, Amita R Somalwar, Namrata Pawar, Dadasaheb M Kokare, Nishikant K Subhedar, Amul J Sakharka. LSD1-BDNF activity in lateral hypothalamus-medial forebrain bundle area is essential for reward seeking behavior. Progress in neurobiology. vol 202. 2021-11-01. PMID:33798614. |
herein, we focus on the role of lsd1 in modulating the expression of brain derived neurotrophic factor (bdnf), the master regulator of synaptic plasticity, in the lateral hypothalamus-medial forebrain bundle (lh-mfb) circuit during positive reinforcement. |
2021-11-01 |
2023-08-13 |
rat |
| Sneha Sagarkar, Amit G Choudhary, Nagalakshmi Balasubramanian, Sanjay N Awathale, Amita R Somalwar, Namrata Pawar, Dadasaheb M Kokare, Nishikant K Subhedar, Amul J Sakharka. LSD1-BDNF activity in lateral hypothalamus-medial forebrain bundle area is essential for reward seeking behavior. Progress in neurobiology. vol 202. 2021-11-01. PMID:33798614. |
lsd1 expression and markers of synaptic plasticity like bdnf and dendritic arborization in the lh, showed distinct increase in conditioned animals. |
2021-11-01 |
2023-08-13 |
rat |
| Louise Martens, Luisa Herrmann, Lejla Colic, Meng Li, Anni Richter, Gusalija Behnisch, Oliver Stork, Constanze Seidenbecher, Björn H Schott, Martin Walte. Met carriers of the BDNF Val66Met polymorphism show reduced Glx/NAA in the pregenual ACC in two independent cohorts. Scientific reports. vol 11. issue 1. 2021-10-25. PMID:33762638. |
the met allele of the val66met snp of the bdnf gene (rs6265) is associated with impaired activity-dependent release of brain-derived neurotrophic factor (bdnf), resulting in reduced synaptic plasticity, impaired glutamatergic neurotransmission, and morphological changes. |
2021-10-25 |
2023-08-13 |
Not clear |
| Alessandro Minutillo, Gabriele Panza, Massimo Carlo Maur. Retraction Note: Musical practice and BDNF plasma levels as a potential marker of synaptic plasticity: an instrument of rehabilitative processes. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 42. issue 7. 2021-10-22. PMID:33945038. |
retraction note: musical practice and bdnf plasma levels as a potential marker of synaptic plasticity: an instrument of rehabilitative processes. |
2021-10-22 |
2023-08-13 |
Not clear |
| Li-Min Mao, Eugene E Fibuch, John Q Wan. Decoding BDNF-LTP coupling in cocaine addiction. Neuron. vol 67. issue 5. 2021-10-20. PMID:20890399. |
bdnf is a neurotrophic peptide that regulates synaptic plasticity. |
2021-10-20 |
2023-08-12 |
Not clear |