| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Khairunnuur Fairuz Azman, Rahimah Zakari. Recent Advances on the Role of Brain-Derived Neurotrophic Factor (BDNF) in Neurodegenerative Diseases. International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35743271. |
the signaling cascades initiated by bdnf and its receptor are the key regulators of synaptic plasticity, which plays important role in learning and memory formation. |
2022-06-24 |
2023-08-14 |
Not clear |
| Chuanwang Tong, Senyang Ca. Study on the mechanism of visual aging in cats' primary visual cortex based on BDNF-TrkB signal pathway. Scientific reports. vol 12. issue 1. 2022-06-22. PMID:35732706. |
to explore the expression of brain-derived neurotrophic factor (bdnf) and specific receptor tyrosine kinase receptor b (trkb) in the primary visual cortex of young and old cats, especially to reveal the age-related differences in the mediating mechanism of bdnf-trkb signaling pathway in cats' visual cortex and their possible effects on synaptic plasticity, nissl staining was used to display neurons in each layer of cats' primary visual cortex, and immunohistochemical abc method was used to label bdnf and trkb immunopositive cells in each layer of cats' primary visual cortex. |
2022-06-22 |
2023-08-14 |
Not clear |
| Beatriz Gutiérrez-Vera, Alejandro Rivera-Olvera, Martha L Escoba. ENVIRONMENTAL ENRICHMENT ATTENUATES CONDITIONED TASTE AVERSION THROUGH THE RESTORATION OF BDNF LEVELS IN THE INSULAR CORTEX. Behavioural brain research. 2022-06-01. PMID:35644274. |
these changes are known to be related to increased levels of some trophic factors, such as brain-derived neurotrophic factor (bdnf), which has been considered a regulatory protein for synaptic plasticity in the adult brain. |
2022-06-01 |
2023-08-13 |
rat |
| Roberto Bonanni, Ida Cariati, Umberto Tarantino, Giovanna D'Arcangelo, Virginia Tancred. Physical Exercise and Health: A Focus on Its Protective Role in Neurodegenerative Diseases. Journal of functional morphology and kinesiology. vol 7. issue 2. 2022-06-01. PMID:35645300. |
in this regard, neurotrophins, such as brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), glia cell line-derived neurotrophic factor (gdnf), neurotrophin-3 (nt-3), and neurotrophin-4 (nt-4), have been suggested as key mediators of brain health benefits, as they are involved in neurogenesis, neuronal survival, and synaptic plasticity. |
2022-06-01 |
2023-08-13 |
Not clear |
| Abdallah Mohammad Ibrahim, Lalita Chauhan, Aditi Bhardwaj, Anjali Sharma, Faizana Fayaz, Bhumika Kumar, Mohamed Alhashmi, Noora AlHajri, Md Sabir Alam, Faheem Hyder Potto. Brain-Derived Neurotropic Factor in Neurodegenerative Disorders. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625880. |
moreover, bdnf has several important roles, such as improving synaptic plasticity and contributing to long-lasting memory formation. |
2022-05-28 |
2023-08-13 |
Not clear |
| Guoli Wang, Tianyue An, Cong Lei, Xiaofeng Zhu, Li Yang, Lianxue Zhang, Ronghua Zhan. Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134-mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression. Journal of ginseng research. vol 46. issue 3. 2022-05-23. PMID:35600767. |
antidepressant-like effect of ginsenoside rb1 on potentiating synaptic plasticity via the mir-134-mediated bdnf signaling pathway in a mouse model of chronic stress-induced depression. |
2022-05-23 |
2023-08-13 |
mouse |
| Maria M Ekblom, E Bojsen-Møller, V Blom, O Tarassova, M Moberg, M Pontén, R Wang, O Ekblo. Acute effects of physical activity patterns on plasma cortisol and brain-derived neurotrophic factor in relation to corticospinal excitability. Behavioural brain research. 2022-05-14. PMID:35568076. |
brain-derived neurotrophic factor (bdnf) and cortisol are both capable of modulating synaptic plasticity, but it is unknown how physical activity-induced changes in their plasma levels relate to corticospinal plasticity in humans. |
2022-05-14 |
2023-08-13 |
Not clear |
| Sarah Ateaque, Spyros Merkouris, Sean Wyatt, Nicholas D Allen, Jia Xie, Peter S DiStefano, Ronald M Lindsay, Yves-Alain Bard. Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC. Journal of neurochemistry. 2022-05-10. PMID:35536742. |
downstream of trk activation, the changes in gene expression caused by trkc activation were found to be similar to those resulting from trkb activation by bdnf, including a number of genes involved in synaptic plasticity. |
2022-05-10 |
2023-08-13 |
human |
| Fatemeh Khani-Habibabadi, Leila Zare, Mohammad Ali Sahraian, Mohammad Javan, Mehrdad Behmanes. Hotair and Malat1 Long Noncoding RNAs Regulate Bdnf Expression and Oligodendrocyte Precursor Cell Differentiation. Molecular neurobiology. 2022-05-02. PMID:35499794. |
brain-derived neurotrophic factor (bdnf) is a member of the neurotrophins family with well-known roles in neural development, differentiation, survival, and synaptic plasticity; however, it has not been explained thoroughly how the expression of this critical gene is regulated. |
2022-05-02 |
2023-08-13 |
rat |
| Charles N S Allen, Sterling P Arjona, Maryline Santerre, Claudio De Lucia, Walter J Koch, Bassel E Saway. Metabolic Reprogramming in HIV-Associated Neurocognitive Disorders. Frontiers in cellular neuroscience. vol 16. 2022-04-14. PMID:35418836. |
the accumulation of probdnf results in signaling that increases the expression of the inducible camp early repressor (icer) protein which then occupies the camp response element (cre)-binding sites within the bdnf promoters ii and iv, thus altering normal synaptic plasticity. |
2022-04-14 |
2023-08-13 |
Not clear |
| Jing Wen, Yaowei Xu, Zhixiang Yu, Yifan Zhou, Wenting Wang, Jingjie Yang, Yiming Wang, Qian Bai, Zhisong L. The cAMP Response Element- Binding Protein/Brain-Derived Neurotrophic Factor Pathway in Anterior Cingulate Cortex Regulates Neuropathic Pain and Anxiodepression Like Behaviors in Rats. Frontiers in molecular neuroscience. vol 15. 2022-04-11. PMID:35401106. |
at the same time, brain-derived neurotrophic factor (bdnf), as important targets of creb, is intricate in neuronal growth, differentiation, as well as the establishment of synaptic plasticity. |
2022-04-11 |
2023-08-13 |
rat |
| Risto Halonen, Liisa Kuula, Jari Lahti, Katri Räikkönen, Anu-Katriina Pesone. The association between overnight recognition accuracy and slow oscillation-spindle coupling is moderated by BDNF Val66Met. Behavioural brain research. 2022-04-11. PMID:35405173. |
brain-derived neurotrophic factor (bdnf) val66met and catechol-o-methyltransferase (comt) val158met are repeatedly reported to implicate the structure and function of prefrontal and hippocampal areas as well as molecular events promoting synaptic plasticity. |
2022-04-11 |
2023-08-13 |
Not clear |
| Sanjay Arora, Takahisa Kanekiyo, Jagdish Sing. Functionalized nanoparticles for brain targeted BDNF gene therapy to rescue Alzheimer's disease pathology in transgenic mouse model. International journal of biological macromolecules. 2022-04-04. PMID:35378156. |
brain-derived neurotrophic factor (bdnf) is actively produced and utilized in cortical circuits throughout life to sustain neuronal function and synaptic plasticity. |
2022-04-04 |
2023-08-13 |
mouse |
| Rundong Liu, Lin Bai, Mengchen Liu, Ruike Wang, Yingying Wu, Qiong Li, Yue Ba, Huizhen Zhang, Guoyu Zhou, Fangfang Yu, Hui Huan. Combined exposure of lead and high-fat diet enhanced cognitive decline via interacting with CREB-BDNF signaling in male rats. Environmental pollution (Barking, Essex : 1987). 2022-04-01. PMID:35364187. |
pb and hfd decreased the levels of synapsin-1, gap-43 and psd-95 protein related to synaptic properties and sirt1, nmdars, phosphorylated creb and bdnf related to synaptic plasticity regulatory, and these decreases was greater when combined exposure. |
2022-04-01 |
2023-08-13 |
rat |
| Antonino Giordano, Ferdinando Clarelli, Miryam Cannizzaro, Elisabetta Mascia, Silvia Santoro, Melissa Sorosina, Laura Ferrè, Letizia Leocani, Federica Esposit. Frontiers in neurology. vol 13. 2022-03-10. PMID:35265024. |
motor recovery depends on synaptic plasticity, in which the brain-derived neurotrophic factor (bdnf) is a key player, through its binding to the neurotrophic-tyrosine kinase-2 (ntrk2) receptor. |
2022-03-10 |
2023-08-13 |
Not clear |
| Mahshid Ebrahimnejad, Paniz Azizi, Vahide Alipour, Mohammad-Reza Zarrindast, Salar Vasegh. Complicated Role of Exercise in Modulating Memory: A Discussion of the Mechanisms Involved. Neurochemical research. 2022-02-23. PMID:35195832. |
in this article, the role of brain-derived neurotrophic factor (bdnf) and tropomyosin receptor kinase b (involved in synaptic plasticity and neurogenesis), and vascular endothelial growth factor, nerve growth factor, insulin-like growth factor 1, inflammatory markers, apoptotic factors, and antioxidant system was discussed in the modulation of exercise effects on memory. |
2022-02-23 |
2023-08-13 |
Not clear |
| Kazunori Suda, Kazunori Matsud. How Microbes Affect Depression: Underlying Mechanisms via the Gut-Brain Axis and the Modulating Role of Probiotics. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35163104. |
short-chain fatty acids such as butyrate are known to contribute to the up-regulation of brain-derived neurotrophic factor (bdnf), and gut dysbiosis causes decreased levels of bdnf, which could affect neuronal development and synaptic plasticity. |
2022-02-15 |
2023-08-13 |
Not clear |
| Joyce Keife. Regulation of AMPAR trafficking in synaptic plasticity by BDNF and the impact of neurodegenerative disease. Journal of neuroscience research. 2022-02-07. PMID:35128708. |
regulation of ampar trafficking in synaptic plasticity by bdnf and the impact of neurodegenerative disease. |
2022-02-07 |
2023-08-13 |
Not clear |
| Joyce Keife. Regulation of AMPAR trafficking in synaptic plasticity by BDNF and the impact of neurodegenerative disease. Journal of neuroscience research. 2022-02-07. PMID:35128708. |
here, research showing that bdnf drives ampars to synapses, ampar trafficking is essential for synaptic plasticity and learning, and that neurodegenerative disease results in a significant decline in bdnf will be reviewed. |
2022-02-07 |
2023-08-13 |
Not clear |
| Jing Gao, Ming-Yin Lai, Thi Tanh-Tam Mai, Wen Fu, Meng-Yu Wang, Bai-le Ning, Wen-Bin F. [Effects of electroacupuncture on BNDF/mTORC1 signaling pathway and synaptic plasticity in prefrontal cortex of rats exposed to chronic unpredictable mild stress]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 1. 2022-02-07. PMID:35128865. |
to investigate the effects of electroacupuncture (ea) on the expression of related proteins in the brain-derived neurotrophic factor (bdnf)/mammalian target of rapamycin complex 1 (mtorc1) signaling pathway and synapse-associated proteins and the density of dendrite spines in the prefrontal cortex (pfc) of depression model rats, and to reveal the underlying mechanism by which ea regulates the synaptic plasticity to improve depressive symptoms. |
2022-02-07 |
2023-08-13 |
rat |