| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Hartmann, R Heumann, V Lessman. Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses. The EMBO journal. vol 20. issue 21. 2001-12-07. PMID:11689429. |
these results support the concept of bdnf being a synaptic messenger of activity-dependent synaptic plasticity, which is released from postsynaptic neurons. |
2001-12-07 |
2023-08-12 |
Not clear |
| S L Patterson, C Pittenger, A Morozov, K C Martin, H Scanlin, C Drake, E R Kande. Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase. Neuron. vol 32. issue 1. 2001-12-04. PMID:11604144. |
long-lasting forms of synaptic plasticity like the late phase of ltp (l-ltp) typically require an elevation of camp, the recruitment of the camp-dependent protein kinase (pka), and ultimately the activation of transcription and translation; some forms also require brain-derived neurotrophic factor (bdnf). |
2001-12-04 |
2023-08-12 |
Not clear |
| M Kojima, N Takei, T Numakawa, Y Ishikawa, S Suzuki, T Matsumoto, R Katoh-Semba, H Nawa, H Hatanak. Biological characterization and optical imaging of brain-derived neurotrophic factor-green fluorescent protein suggest an activity-dependent local release of brain-derived neurotrophic factor in neurites of cultured hippocampal neurons. Journal of neuroscience research. vol 64. issue 1. 2001-07-12. PMID:11276045. |
optical studies using bdnf-gfp may provide important evidence regarding the participation of bdnf in synaptic plasticity. |
2001-07-12 |
2023-08-12 |
Not clear |
| M Gooney, M A Lync. Long-term potentiation in the dentate gyrus of the rat hippocampus is accompanied by brain-derived neurotrophic factor-induced activation of TrkB. Journal of neurochemistry. vol 77. issue 5. 2001-07-12. PMID:11389170. |
a role for neurotrophic factors, in particular brain-derived neurotrophic factor (bdnf), in modulating synaptic plasticity in the adult brain has been described in recent years by several laboratories. |
2001-07-12 |
2023-08-12 |
rat |
| G Aakalu, W B Smith, N Nguyen, C Jiang, E M Schuma. Dynamic visualization of local protein synthesis in hippocampal neurons. Neuron. vol 30. issue 2. 2001-06-28. PMID:11395009. |
in cultured hippocampal neurons, we show that bdnf, a growth factor involved in synaptic plasticity, stimulates protein synthesis of the reporter in intact, mechanically, or "optically" isolated dendrites. |
2001-06-28 |
2023-08-12 |
Not clear |
| C Cirelli, G Tonon. Differential expression of plasticity-related genes in waking and sleep and their regulation by the noradrenergic system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 24. 2001-02-22. PMID:11124996. |
here we show that the expression of phosphorylated cre-binding protein, arc, and bdnf, three genes whose induction is often associated with synaptic plasticity, is high during waking and low during sleep. |
2001-02-22 |
2023-08-12 |
Not clear |
| M Mizuno, K Yamada, A Olariu, H Nawa, T Nabeshim. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995859. |
brain-derived neurotrophic factor (bdnf) regulates both short-term synaptic functions and activity-dependent synaptic plasticity such as long-term potentiation. |
2000-10-18 |
2023-08-12 |
rat |
| J Du, L Feng, F Yang, B L. Activity- and Ca(2+)-dependent modulation of surface expression of brain-derived neurotrophic factor receptors in hippocampal neurons. The Journal of cell biology. vol 150. issue 6. 2000-10-12. PMID:10995446. |
brain-derived neurotrophic factor (bdnf) has been shown to regulate neuronal survival and synaptic plasticity in the central nervous system (cns) in an activity-dependent manner, but the underlying mechanisms remain unclear. |
2000-10-12 |
2023-08-12 |
Not clear |
| T Araki, M Yamada, H Ohnishi, S I Sano, H Hatanak. BIT/SHPS-1 enhances brain-derived neurotrophic factor-promoted neuronal survival in cultured cerebral cortical neurons. Journal of neurochemistry. vol 75. issue 4. 2000-10-05. PMID:10987830. |
brain-derived neurotrophic factor (bdnf) activates a variety of signaling molecules to exert various functions in the nervous system, including neuronal differentiation, survival, and regulation of synaptic plasticity. |
2000-10-05 |
2023-08-12 |
rat |
| H Takag. [Neuronal cytokine involvement in synaptic plasticity]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 115. issue 4. 2000-10-02. PMID:10876804. |
these results suggested that the new synaptic sites, products of the bdnf induced l-ltp, will play an important role in synaptic plasticity (ex. |
2000-10-02 |
2023-08-12 |
Not clear |
| S A Nanda, K J Mac. Seizures and sensory stimulation result in different patterns of brain derived neurotrophic factor protein expression in the barrel cortex and hippocampus. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891580. |
brain-derived neurotrophic factor (bdnf) is important for the development and trophic support of neurons, and may be involved in controlling axonal sprouting and synaptic plasticity. |
2000-09-25 |
2023-08-12 |
rat |
| J L Hanover, Z J Huang, S Tonegawa, M P Stryke. Brain-derived neurotrophic factor overexpression induces precocious critical period in mouse visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 22. 2000-06-21. PMID:10559430. |
brain-derived neurotrophic factor (bdnf) is a candidate molecule for regulating activity-dependent synaptic plasticity on the grounds of its expression pattern in developing visual cortex and that of its receptor, trkb (castr¿n et al., 1992; bozzi et al., 1995; schoups et al., 1995; cabelli et al., 1996), as well as the modulation of these patterns by activity (castr¿n et al., 1992; bozzi et al., 1995; schoups et al., 1995). |
2000-06-21 |
2023-08-12 |
mouse |
| D Muller, Z Djebbara-Hannas, P Jourdain, L Vutskits, P Durbec, G Rougon, J Z Kis. Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 8. 2000-05-17. PMID:10760298. |
these results suggest that one action of psa-ncam could be to sensitize pyramidal neurons to bdnf, thereby modulating activity-dependent synaptic plasticity. |
2000-05-17 |
2023-08-12 |
mouse |
| J P Fawcett, M A Alonso-Vanegas, S J Morris, F D Miller, A F Sadikot, R A Murph. Evidence that brain-derived neurotrophic factor from presynaptic nerve terminals regulates the phenotype of calbindin-containing neurons in the lateral septum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 1. 2000-01-27. PMID:10627605. |
brain-derived neurotrophic factor (bdnf) is transported anterogradely in neurons of the cns and can be released by activity-dependent mechanisms to regulate synaptic plasticity. |
2000-01-27 |
2023-08-12 |
rat |
| W A Gottschalk, H Jiang, N Tartaglia, L Feng, A Figurov, B L. Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus. Learning & memory (Cold Spring Harbor, N.Y.). vol 6. issue 3. 1999-10-19. PMID:10492006. |
signaling mechanisms mediating bdnf modulation of synaptic plasticity in the hippocampus. |
1999-10-19 |
2023-08-12 |
Not clear |
| W A Gottschalk, H Jiang, N Tartaglia, L Feng, A Figurov, B L. Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus. Learning & memory (Cold Spring Harbor, N.Y.). vol 6. issue 3. 1999-10-19. PMID:10492006. |
although recent studies indicate that brain-derived neurotrophic factor (bdnf) plays an important role in hippocampal synaptic plasticity, the underlying signaling mechanisms remain largely unknown. |
1999-10-19 |
2023-08-12 |
Not clear |
| C Gaiddon, Y Larmet, E Trinh, A L Boutillier, B Sommer, J P Loeffle. Brain-derived neurotrophic factor exerts opposing effects on beta2-adrenergic receptor according to depolarization status of cerebellar neurons. Journal of neurochemistry. vol 73. issue 4. 1999-10-14. PMID:10501191. |
to investigate the molecular mechanisms underlying brain-derived neurotrophic factor (bdnf)-controlled synaptic plasticity, we studied beta2-adrenergic receptor (beta2-ar) expression in cultured cerebellar granule cells. |
1999-10-14 |
2023-08-12 |
Not clear |
| M Yuzaki, T Furuichi, K Mikoshiba, Y Kagaw. A stimulus paradigm inducing long-term desensitization of AMPA receptors evokes a specific increase in BDNF mRNA in cerebellar slices. Learning & memory (Cold Spring Harbor, N.Y.). vol 1. issue 4. 1999-09-29. PMID:10467600. |
these results indicate that bdnf may be coinduced with ltda and suggest that the slow and sustained increase of bdnf mrna might play a role in later phases of synaptic plasticity in the cerebellum. |
1999-09-29 |
2023-08-12 |
Not clear |
| J S Mu, W P Li, Z B Yao, X F Zho. Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats. Brain research. vol 835. issue 2. 1999-09-28. PMID:10415381. |
brain-derived neurotrophic factor (bdnf) is abundantly expressed in the hippocampus and cerebral cortex and is involved in synaptic plasticity and long-term potentiation (ltp). |
1999-09-28 |
2023-08-12 |
rat |
| S Y Lin, K Wu, G W Len, J L Xu, E S Levine, P C Suen, H T Mount, I B Blac. Brain-derived neurotrophic factor enhances association of protein tyrosine phosphatase PTP1D with the NMDA receptor subunit NR2B in the cortical postsynaptic density. Brain research. Molecular brain research. vol 70. issue 1. 1999-09-21. PMID:10381539. |
our recent studies revealed that brain-derived neurotrophic factor (bdnf) rapidly enhances tyrosine phosphorylation and dephosphorylation of the nmda receptor subunit, nr2b, in the postsynaptic density (psd), potentially regulating synaptic plasticity. |
1999-09-21 |
2023-08-12 |
rat |