| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| William J Tyler, Mariana Alonso, Clive R Bramham, Lucas D Pozzo-Mille. From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learning & memory (Cold Spring Harbor, N.Y.). vol 9. issue 5. 2002-11-15. PMID:12359832. |
brain-derived neurotrophic factor (bdnf) has recently emerged as one of the most potent molecular mediators of not only central synaptic plasticity, but also behavioral interactions between an organism and its environment. |
2002-11-15 |
2023-08-12 |
Not clear |
| Robert Blum, Karl W Kafitz, Arthur Konnert. Neurotrophin-evoked depolarization requires the sodium channel Na(V)1.9. Nature. vol 419. issue 6908. 2002-11-08. PMID:12384689. |
many types of neurons in the central nervous system are excited by bdnf or neurotrophin-4/5, an action that has recently been implicated in synaptic plasticity. |
2002-11-08 |
2023-08-12 |
Not clear |
| Liliana Minichiello, Anna Maria Calella, Diego L Medina, Tobias Bonhoeffer, Rüdiger Klein, Martin Kort. Mechanism of TrkB-mediated hippocampal long-term potentiation. Neuron. vol 36. issue 1. 2002-11-04. PMID:12367511. |
the trkb receptor tyrosine kinase and its ligand, bdnf, have an essential role in certain forms of synaptic plasticity. |
2002-11-04 |
2023-08-12 |
mouse |
| Yuji Ikegaya, Yoko Ishizaka, Norio Matsuk. BDNF attenuates hippocampal LTD via activation of phospholipase C: implications for a vertical shift in the frequency-response curve of synaptic plasticity. The European journal of neuroscience. vol 16. issue 1. 2002-10-09. PMID:12153539. |
bdnf attenuates hippocampal ltd via activation of phospholipase c: implications for a vertical shift in the frequency-response curve of synaptic plasticity. |
2002-10-09 |
2023-08-12 |
rat |
| R Molteni, R J Barnard, Z Ying, C K Roberts, F Gómez-Pinill. A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088740. |
consequent to the action of bdnf on synaptic function, downstream effectors for the action of bdnf on synaptic plasticity were reduced proportionally to bdnf levels, in the hippocampus of rats maintained on the hfs diet between 2 and 24 months. |
2002-09-03 |
2023-08-12 |
rat |
| Nicole C Berchtold, J Patrick Kesslak, Carl W Cotma. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of neuroscience research. vol 68. issue 5. 2002-08-12. PMID:12111841. |
brain-derived neurotrophic factor (bdnf) enhances synaptic plasticity and neuron function. |
2002-08-12 |
2023-08-12 |
Not clear |
| Kobi Rosenblum, Marie Futter, Karen Voss, Muriel Erent, Paul A Skehel, Pim French, Louis Obosi, Matt W Jones, Tim V P Blis. The role of extracellular regulated kinases I/II in late-phase long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 13. 2002-07-29. PMID:12097495. |
to test whether the induction of persistent synaptic plasticity by stimuli such as bdnf is associated with nuclear translocation of erki/ii, we expressed enhanced green fluorescent protein (egfp)-erkii in pc12 cell lines and primary cortical cultures. |
2002-07-29 |
2023-08-12 |
Not clear |
| Susan G Dorsey, Linda L Bambrick, Rita J Balice-Gordon, Bruce K Kruege. Failure of brain-derived neurotrophic factor-dependent neuron survival in mouse trisomy 16. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923422. |
the neurotrophin, brain derived neurotrophic factor (bdnf), exerts multiple effects on the development and maintenance of the nervous system, including regulating synaptic plasticity and promoting neuron survival. |
2002-04-08 |
2023-08-12 |
mouse |
| Shui-Wang Ying, Marie Futter, Kobi Rosenblum, Mark J Webber, Stephen P Hunt, Timothy V P Bliss, Clive R Bramha. Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 5. 2002-03-22. PMID:11880483. |
brain-derived neurotrophic factor (bdnf) is implicated in long-term synaptic plasticity in the adult hippocampus, but the cellular mechanisms are little understood. |
2002-03-22 |
2023-08-12 |
Not clear |
| Alexandre R Carter, Chinfei Chen, Phillip M Schwartz, Rosalind A Sega. Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850459. |
these data suggest that bdnf regulates both the mechanisms that underlie short-term synaptic plasticity and the steady-state relationship between different vesicle pools within the terminal. |
2002-02-26 |
2023-08-12 |
mouse |
| Kiyofumi Yamada, Makoto Mizuno, Toshitaka Nabeshim. Role for brain-derived neurotrophic factor in learning and memory. Life sciences. vol 70. issue 7. 2002-02-22. PMID:11833737. |
long-term potentiation, a form of synaptic plasticity, is markedly impaired in bdnf mutant mice, but the changes were restored by the re-expression of bdnf. |
2002-02-22 |
2023-08-12 |
mouse |
| A H Kossel, S B Cambridge, U Wagner, T Bonhoeffe. A caged Ab reveals an immediate/instructive effect of BDNF during hippocampal synaptic potentiation. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 25. 2002-01-10. PMID:11724927. |
our experiments therefore strengthen the view that endogenous bdnf has fast effects during induction of synaptic plasticity. |
2002-01-10 |
2023-08-12 |
Not clear |
| M Hartmann, R Heumann, V Lessman. Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses. The EMBO journal. vol 20. issue 21. 2001-12-07. PMID:11689429. |
the protein brain-derived neurotrophic factor (bdnf) has been postulated to be a retrograde or paracrine synaptic messenger in long-term potentiation and other forms of activity-dependent synaptic plasticity. |
2001-12-07 |
2023-08-12 |
Not clear |
| M Hartmann, R Heumann, V Lessman. Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses. The EMBO journal. vol 20. issue 21. 2001-12-07. PMID:11689429. |
these results support the concept of bdnf being a synaptic messenger of activity-dependent synaptic plasticity, which is released from postsynaptic neurons. |
2001-12-07 |
2023-08-12 |
Not clear |
| S L Patterson, C Pittenger, A Morozov, K C Martin, H Scanlin, C Drake, E R Kande. Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase. Neuron. vol 32. issue 1. 2001-12-04. PMID:11604144. |
long-lasting forms of synaptic plasticity like the late phase of ltp (l-ltp) typically require an elevation of camp, the recruitment of the camp-dependent protein kinase (pka), and ultimately the activation of transcription and translation; some forms also require brain-derived neurotrophic factor (bdnf). |
2001-12-04 |
2023-08-12 |
Not clear |
| M Kojima, N Takei, T Numakawa, Y Ishikawa, S Suzuki, T Matsumoto, R Katoh-Semba, H Nawa, H Hatanak. Biological characterization and optical imaging of brain-derived neurotrophic factor-green fluorescent protein suggest an activity-dependent local release of brain-derived neurotrophic factor in neurites of cultured hippocampal neurons. Journal of neuroscience research. vol 64. issue 1. 2001-07-12. PMID:11276045. |
optical studies using bdnf-gfp may provide important evidence regarding the participation of bdnf in synaptic plasticity. |
2001-07-12 |
2023-08-12 |
Not clear |
| M Gooney, M A Lync. Long-term potentiation in the dentate gyrus of the rat hippocampus is accompanied by brain-derived neurotrophic factor-induced activation of TrkB. Journal of neurochemistry. vol 77. issue 5. 2001-07-12. PMID:11389170. |
a role for neurotrophic factors, in particular brain-derived neurotrophic factor (bdnf), in modulating synaptic plasticity in the adult brain has been described in recent years by several laboratories. |
2001-07-12 |
2023-08-12 |
rat |
| G Aakalu, W B Smith, N Nguyen, C Jiang, E M Schuma. Dynamic visualization of local protein synthesis in hippocampal neurons. Neuron. vol 30. issue 2. 2001-06-28. PMID:11395009. |
in cultured hippocampal neurons, we show that bdnf, a growth factor involved in synaptic plasticity, stimulates protein synthesis of the reporter in intact, mechanically, or "optically" isolated dendrites. |
2001-06-28 |
2023-08-12 |
Not clear |
| C Cirelli, G Tonon. Differential expression of plasticity-related genes in waking and sleep and their regulation by the noradrenergic system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 24. 2001-02-22. PMID:11124996. |
here we show that the expression of phosphorylated cre-binding protein, arc, and bdnf, three genes whose induction is often associated with synaptic plasticity, is high during waking and low during sleep. |
2001-02-22 |
2023-08-12 |
Not clear |
| M Mizuno, K Yamada, A Olariu, H Nawa, T Nabeshim. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995859. |
brain-derived neurotrophic factor (bdnf) regulates both short-term synaptic functions and activity-dependent synaptic plasticity such as long-term potentiation. |
2000-10-18 |
2023-08-12 |
rat |