| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oleg V Dolotov, Ekaterina A Karpenko, Tamara S Seredenina, Lyudmila S Inozemtseva, Natalia G Levitskaya, Yuriy A Zolotarev, Andrey A Kamensky, Igor A Grivennikov, Juergen Engele, Nikolay F Myasoedo. Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain. Journal of neurochemistry. vol 97 Suppl 1. 2006-05-23. PMID:16635254. |
a clue to the molecular mechanism underlying this neurotropic action was recently given by the observation that semax stimulates the synthesis of brain-derived neurotrophic factor (bdnf), a potent modulator of synaptic plasticity, in astrocytes cultured from rat basal forebrain. |
2006-05-23 |
2023-08-12 |
rat |
| Dean-Chuan Wang, Shun-Sheng Chen, Yi-Ching Lee, Tsan-Ju Che. Amyloid-beta at sublethal level impairs BDNF-induced arc expression in cortical neurons. Neuroscience letters. vol 398. issue 1-2. 2006-05-10. PMID:16412575. |
consistent with the literature, arc, an indicator of synaptic plasticity, was induced by bdnf (25 ng/ml) in both dose- and time-dependent manners. |
2006-05-10 |
2023-08-12 |
rat |
| Tomoya Matsumoto, Tadahiro Numakawa, Daisaku Yokomaku, Naoki Adachi, Satoru Yamagishi, Yumiko Numakawa, Hiroshi Kunugi, Takahisa Taguch. Brain-derived neurotrophic factor-induced potentiation of glutamate and GABA release: different dependency on signaling pathways and neuronal activity. Molecular and cellular neurosciences. vol 31. issue 1. 2006-05-08. PMID:16214365. |
in conclusion, bdnf potentiates the excitatory and inhibitory system separately, which may be important for the regulation of synaptic plasticity. |
2006-05-08 |
2023-08-12 |
Not clear |
| Diana V Castillo, Yazmín Figueroa-Guzmán, Martha L Escoba. Brain-derived neurotrophic factor enhances conditioned taste aversion retention. Brain research. vol 1067. issue 1. 2006-05-02. PMID:16364259. |
brain-derived neurotrophic factor (bdnf) has recently emerged as one of the most potent molecular mediators of not only central synaptic plasticity, but also behavioral interactions between an organism and its environment. |
2006-05-02 |
2023-08-12 |
rat |
| Diana V Castillo, Yazmín Figueroa-Guzmán, Martha L Escoba. Brain-derived neurotrophic factor enhances conditioned taste aversion retention. Brain research. vol 1067. issue 1. 2006-05-02. PMID:16364259. |
these findings support the concept that bdnf may contribute to memory-related functions performed by a neocortical area, playing a critical role in long-term synaptic plasticity. |
2006-05-02 |
2023-08-12 |
rat |
| Robert H Ring, Janet Alder, Myles Fennell, Evguenia Kouranova, Ira B Black, Smita Thakker-Vari. Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth. Journal of neurobiology. vol 66. issue 4. 2006-04-28. PMID:16408296. |
we previously found that bdnf treatment acutely increases transcription of the synaptic vesicle protein rab3a, required for trophin-induced synaptic plasticity, as well as the peptide vgf, which increases during learning. |
2006-04-28 |
2023-08-12 |
Not clear |
| Robert H Ring, Janet Alder, Myles Fennell, Evguenia Kouranova, Ira B Black, Smita Thakker-Vari. Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth. Journal of neurobiology. vol 66. issue 4. 2006-04-28. PMID:16408296. |
consistent with the modulation of synaptic plasticity, bdnf treatment (3-6 h) induced mrnas encoding the synapse-associated proteins synaptojanin 2, neuronal pentraxin 1, septin 9, and ryanodine receptor 2. |
2006-04-28 |
2023-08-12 |
Not clear |
| Aiguo Wu, Zhe Ying, Fernando Gomez-Pinill. Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition. Experimental neurology. vol 197. issue 2. 2006-04-03. PMID:16364299. |
the analysis was focused on the bdnf system based on its action on synaptic plasticity and cognition by modulating synapsin i and creb. |
2006-04-03 |
2023-08-12 |
rat |
| Aiguo Wu, Zhe Ying, Fernando Gomez-Pinill. Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition. Experimental neurology. vol 197. issue 2. 2006-04-03. PMID:16364299. |
these results are in agreement with previous evidence, showing that oxidative stress can affect the injured brain by acting through the bdnf system to affect synaptic plasticity and cognition. |
2006-04-03 |
2023-08-12 |
rat |
| Wei Guo, Meredith T Robbins, Feng Wei, Shiping Zou, Ronald Dubner, Ke Re. Supraspinal brain-derived neurotrophic factor signaling: a novel mechanism for descending pain facilitation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 1. 2006-03-31. PMID:16399679. |
in the adult mammalian brain, brain-derived neurotrophic factor (bdnf) is critically involved in long-term synaptic plasticity. |
2006-03-31 |
2023-08-12 |
Not clear |
| Nobuyuki Shiina, Kazumi Shinkura, Makio Tokunag. A novel RNA-binding protein in neuronal RNA granules: regulatory machinery for local translation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 17. 2006-03-09. PMID:15858068. |
dissociation of rng105 from the rna granules is induced by bdnf, a growth factor responsible for synaptic plasticity. |
2006-03-09 |
2023-08-12 |
Not clear |
| Zachary C Baquet, Paula C Bickford, Kevin R Jone. Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 26. 2006-02-14. PMID:15987955. |
brain-derived neurotrophic factor (bdnf) has been implicated in regulating neuronal survival, differentiation, and synaptic plasticity. |
2006-02-14 |
2023-08-12 |
mouse |
| Bryan W Luikart, Serge Nef, Tuhin Virmani, Mark E Lush, Yajuan Liu, Ege T Kavalali, Luis F Parad. TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 15. 2006-02-13. PMID:15829629. |
to gain additional insight into the mechanism of bdnf and trkb influence on synapse formation and synaptic plasticity, we generated a conditional knock-out for trkb using the cre/loxp system. |
2006-02-13 |
2023-08-12 |
mouse |
| F Fumagalli, G Racagni, M A Riv. The expanding role of BDNF: a therapeutic target for Alzheimer's disease? The pharmacogenomics journal. vol 6. issue 1. 2006-02-13. PMID:16314887. |
this review will focus on different pharmacological interventions that are currently in use or drugs under development, narrowing the therapeutic agents to those that interfere with the expression of the trophic factor brain-derived neurotrophic factor (bdnf), a molecule playing a pivotal role in synaptic plasticity and cognition. |
2006-02-13 |
2023-08-12 |
Not clear |
| Mariana Alonso, Pedro Bekinschtein, Martín Cammarota, Monica R M Vianna, Iván Izquierdo, Jorge H Medin. Endogenous BDNF is required for long-term memory formation in the rat parietal cortex. Learning & memory (Cold Spring Harbor, N.Y.). vol 12. issue 5. 2006-01-23. PMID:16204202. |
brain-derived neurotrophic factor (bdnf) modulates both short-term synaptic function and activity-dependent synaptic plasticity in hippocampal and cortical neurons. |
2006-01-23 |
2023-08-12 |
human |
| Rebeca Martínez-Turrillas, Joaquín Del Río, Diana Frechill. Sequential changes in BDNF mRNA expression and synaptic levels of AMPA receptor subunits in rat hippocampus after chronic antidepressant treatment. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16143352. |
the results suggest that paroxetine, but not desipramine, enhances synaptic plasticity in the hippocampus by increasing bdnf mrna expression, which determines a later ampar subunit trafficking to synaptic membranes. |
2006-01-17 |
2023-08-12 |
rat |
| Clive R Bramham, Elhoucine Messaoud. BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Progress in neurobiology. vol 76. issue 2. 2005-12-15. PMID:16099088. |
bdnf function in adult synaptic plasticity: the synaptic consolidation hypothesis. |
2005-12-15 |
2023-08-12 |
Not clear |
| Clive R Bramham, Elhoucine Messaoud. BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Progress in neurobiology. vol 76. issue 2. 2005-12-15. PMID:16099088. |
despite individual breakthroughs, an integrated understanding of bdnf function in synaptic plasticity is lacking. |
2005-12-15 |
2023-08-12 |
Not clear |
| Shih-Jen Tsa. Possible involvement of brain-derived neurotrophic factor in the antinociceptive effect of antidepressants in neuropathic pain. Medical hypotheses. vol 65. issue 3. 2005-10-27. PMID:15905042. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophic factor family, can modulate synaptic plasticity and neurotransmitter release across multiple neurotransmitter systems. |
2005-10-27 |
2023-08-12 |
human |
| Lisa M Rattiner, Michael Davis, Kerry J Ressle. Brain-derived neurotrophic factor in amygdala-dependent learning. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 11. issue 4. 2005-10-19. PMID:16061519. |
the neurotrophin brain-derived neurotrophic factor (bdnf) has recently emerged as a possible molecular mediator of activity-dependent synaptic plasticity underlying learning and memory. |
2005-10-19 |
2023-08-12 |
Not clear |