Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mattias Rickhag, Maria Teilum, Tadeusz Wieloc. Rapid and long-term induction of effector immediate early genes (BDNF, Neuritin and Arc) in peri-infarct cortex and dentate gyrus after ischemic injury in rat brain. Brain research. vol 1151. 2007-07-24. PMID:17397810. |
brain-derived neurotrophic factor (bdnf), neuritin and activity-regulated cytoskeleton-associated protein (arc) belong to a subgroup of immediate early genes implicated in synaptic plasticity known as effector immediate early genes. |
2007-07-24 |
2023-08-12 |
rat |
Christoph Laske, Elke Stransky, Gerhard W Eschweiler, Reinhild Klein, Andreas Wittorf, Thomas Leyhe, Elke Richartz, Niklas Köhler, Matthias Bartels, Gerhard Buchkremer, Klaus Schot. Increased BDNF serum concentration in fibromyalgia with or without depression or antidepressants. Journal of psychiatric research. vol 41. issue 7. 2007-07-16. PMID:16600301. |
brain-derived neurotrophic factor (bdnf) is an endogenous protein involved in neuronal survival and synaptic plasticity of the central and peripheral nervous system (cns and pns). |
2007-07-16 |
2023-08-12 |
Not clear |
Timothy W Bredy, Hao Wu, Cortney Crego, Jessica Zellhoefer, Yi E Sun, Mark Bara. Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learning & memory (Cold Spring Harbor, N.Y.). vol 14. issue 4. 2007-07-03. PMID:17522015. |
since brain-derived neurotrophic factor (bdnf) is crucial for synaptic plasticity and for the maintenance of long-term memory, we examined histone modifications around two bdnf gene promoters after extinction of cued fear, as potential targets of learning-induced epigenetic regulation of gene expression. |
2007-07-03 |
2023-08-12 |
human |
Margarida V Caldeira, Carlos V Melo, Daniela B Pereira, Ricardo Carvalho, Susana S Correia, Donald S Backos, Ana Luísa Carvalho, José A Esteban, Carlos B Duart. Brain-derived neurotrophic factor regulates the expression and synaptic delivery of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons. The Journal of biological chemistry. vol 282. issue 17. 2007-06-14. PMID:17337442. |
brain-derived neurotrophic factor (bdnf) plays an important role in synaptic plasticity in the hippocampus, but the mechanisms involved are not fully understood. |
2007-06-14 |
2023-08-12 |
Not clear |
Yui Naoe, Takahiro Shinkai, Hiroko Hori, Yuko Fukunaka, Kensuke Utsunomiya, Shinichi Sakata, Chima Matsumoto, Kazuko Shimizu, Rudi Hwang, Osamu Ohmori, Jun Nakamur. No association between the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and schizophrenia in Asian populations: Evidence from a case-control study and meta-analysis. Neuroscience letters. vol 415. issue 2. 2007-05-22. PMID:17267117. |
brain-derived neurotrophic factor (bdnf) is a nerve growth factor that plays an important role in the development and maintenance of adult neurons and is important regulator of synaptic plasticity in human brain. |
2007-05-22 |
2023-08-12 |
human |
C Laske, E Stransky, T Leyhe, G W Eschweiler, A Wittorf, E Richartz, M Bartels, G Buchkremer, K Schot. Stage-dependent BDNF serum concentrations in Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 9. 2007-05-02. PMID:16362629. |
bdnf is an endogenous protein involved in the maintenance of neuronal function, synaptic plasticity and structural integrity in the adult brain. |
2007-05-02 |
2023-08-12 |
Not clear |
Michelle D Amaral, Christopher A Chapleau, Lucas Pozzo-Mille. Transient receptor potential channels as novel effectors of brain-derived neurotrophic factor signaling: potential implications for Rett syndrome. Pharmacology & therapeutics. vol 113. issue 2. 2007-04-19. PMID:17118456. |
outlined in the following review is a synopsis of neurotrophin signaling with a particular focus upon brain-derived neurotrophic factor (bdnf) and its role in hippocampal synaptic plasticity and neuronal ca(2+) homeostasis. |
2007-04-19 |
2023-08-12 |
Not clear |
Christoph Laske, Elke Stransky, Thomas Leyhe, Gerhard W Eschweiler, Walter Maetzler, Andreas Wittorf, Surjo Soekadar, Elke Richartz, Niklas Koehler, Mathias Bartels, Gerhard Buchkremer, Klaus Schot. BDNF serum and CSF concentrations in Alzheimer's disease, normal pressure hydrocephalus and healthy controls. Journal of psychiatric research. vol 41. issue 5. 2007-04-10. PMID:16554070. |
bdnf is an endogenous protein involved in the maintenance of neuronal function, synaptic plasticity and structural integrity in the adult brain. |
2007-04-10 |
2023-08-12 |
human |
M A Carrasco, P A Castro, F J Sepulveda, M Cuevas, J C Tapia, P Izaurieta, B van Zundert, L G Aguay. Anti-homeostatic synaptic plasticity of glycine receptor function after chronic strychnine in developing cultured mouse spinal neurons. Journal of neurochemistry. vol 100. issue 5. 2007-04-02. PMID:17217420. |
this phenomenon of synaptic plasticity was blocked by ttx, an antibody against brain-derived neurotrophic factor (bdnf) and k252a suggesting the involvement of the neuronal activity-dependent bdnf-trkb signaling pathway. |
2007-04-02 |
2023-08-12 |
mouse |
Ismail Abidin, Torben Köhler, Elke Weiler, Georg Zoidl, Ulf T Eysel, Volkmar Lessmann, Thomas Mittman. Reduced presynaptic efficiency of excitatory synaptic transmission impairs LTP in the visual cortex of BDNF-heterozygous mice. The European journal of neuroscience. vol 24. issue 12. 2007-03-06. PMID:17229100. |
here we studied the cellular mechanisms of bdnf-mediated changes in synaptic plasticity, excitatory synaptic transmission and long-term potentiation (ltp) in the visual cortex of heterozygous bdnf-knockout mice (bdnf(+/-)). |
2007-03-06 |
2023-08-12 |
mouse |
Fei Xu, Mark R Plummer, Guo-Wei Len, Takanobu Nakazawa, Tadashi Yamamoto, Ira B Black, Kuo W. Brain-derived neurotrophic factor rapidly increases NMDA receptor channel activity through Fyn-mediated phosphorylation. Brain research. vol 1121. issue 1. 2007-02-12. PMID:17045972. |
brain-derived neurotrophic factor (bdnf) is a potent modulator of hippocampal synaptic plasticity. |
2007-02-12 |
2023-08-12 |
mouse |
Jason P Magby, Caixia Bi, Zhe-Yu Chen, Francis S Lee, Mark R Plumme. Single-cell characterization of retrograde signaling by brain-derived neurotrophic factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 52. 2007-02-01. PMID:17192436. |
brain-derived neurotrophic factor (bdnf) is a key regulator of hippocampal synaptic plasticity in the developing and adult nervous system. |
2007-02-01 |
2023-08-12 |
Not clear |
Masaaki Tsuda, Daichi Hara, Makoto Yasuda, Mamoru Fukuchi, Akiko Tabuch. [Role of activity-dependent gene expression of BDNF gene in synaptic plasticity]. Seikagaku. The Journal of Japanese Biochemical Society. vol 78. issue 10. 2007-01-19. PMID:17131884. |
[role of activity-dependent gene expression of bdnf gene in synaptic plasticity]. |
2007-01-19 |
2023-08-12 |
Not clear |
C Laske, G W Eschweile. [Brain-derived neurotrophic factor: from nerve growth factor to modulator of brain plasticity in cognitive processes and psychiatric diseases]. Der Nervenarzt. vol 77. issue 5. 2006-12-26. PMID:16078056. |
the proform of bdnf (pro-bdnf) is secreted and cleaved extracellularly by the serine protease plasmin to mature bdnf, which potentiates synaptic plasticity and long-term potentiation. |
2006-12-26 |
2023-08-12 |
Not clear |
Lucas Pozzo-Mille. BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neurons. Brain research. vol 1104. issue 1. 2006-11-30. PMID:16797499. |
due to the critical role of postsynaptic ca(2+) signals in dendritic development and synaptic plasticity, we tested whether long-term exposure to bdnf affects ca(2+) elevations evoked by coincident excitatory postsynaptic potentials (epsps) and back-propagating action potentials (baps) in spiny dendrites of ca1 pyramidal neurons within hippocampal slice cultures. |
2006-11-30 |
2023-08-12 |
Not clear |
Rosemarie Drake-Bauman. Activity-dependent modulation of inhibition in Purkinje cells by TrkB ligands. Cerebellum (London, England). vol 5. issue 3. 2006-11-28. PMID:16997754. |
this mini review examines the roles of trkb receptor activation by bdnf particularly in relation to activity-dependent synaptic plasticity on purkinje cells and recent studies on the acute modulation of gabaergic synapses by bdnf. |
2006-11-28 |
2023-08-12 |
Not clear |
In Koo Hwang, Ki-Yeon Yoo, Boo-Kyoung Jung, Jun Hwi Cho, Do-Hoon Kim, Tae-Cheon Kang, Young-Guen Kwon, Yong-Sun Kim, Moo Ho Wo. Correlations between neuronal loss, decrease of memory, and decrease expression of brain-derived neurotrophic factor in the gerbil hippocampus during normal aging. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16678162. |
it is known that the hippocampus has vital functions in learning and memory, behavioral regulation, and activity-dependent synaptic plasticity, and that the hippocampus contains high levels of brain-derived neurotrophic factor (bdnf). |
2006-11-14 |
2023-08-12 |
Not clear |
Ming D Qian, Jie Zhang, Xiang-Yang Tan, Andrew Wood, Davinder Gill, Seongeun Ch. Novel agonist monoclonal antibodies activate TrkB receptors and demonstrate potent neurotrophic activities. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 37. 2006-10-20. PMID:16971523. |
tyrosine kinase receptor b (trkb) mediates neurotrophic effects of brain-derived neurotrophic factor (bdnf) to increase neuronal survival, differentiation, synaptic plasticity, and neurogenesis. |
2006-10-20 |
2023-08-12 |
mouse |
Sjoukje D Kuipers, Clive R Bramha. Brain-derived neurotrophic factor mechanisms and function in adult synaptic plasticity: new insights and implications for therapy. Current opinion in drug discovery & development. vol 9. issue 5. 2006-10-19. PMID:17002218. |
brain-derived neurotrophic factor (bdnf) has emerged as a major regulator of synaptic plasticity and a key target in disorders such as major depression and alzheimner's disease. |
2006-10-19 |
2023-08-12 |
Not clear |
Sjoukje D Kuipers, Clive R Bramha. Brain-derived neurotrophic factor mechanisms and function in adult synaptic plasticity: new insights and implications for therapy. Current opinion in drug discovery & development. vol 9. issue 5. 2006-10-19. PMID:17002218. |
this review discusses findings that link bdnf mechanisms in synaptic plasticity to disease mechanisms and possible future therapies. |
2006-10-19 |
2023-08-12 |
Not clear |