Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Linda Lin-yan Wu, Yongjun Fan, Shihua Li, Xiao-Jiang Li, Xin-Fu Zho. Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release. The Journal of biological chemistry. vol 285. issue 8. 2010-03-11. PMID:19996106. |
brain-derived neurotrophic factor (bdnf) plays a pivotal role in brain development and synaptic plasticity. |
2010-03-11 |
2023-08-12 |
mouse |
Camille Robinet, Luc Pelleri. Brain-derived neurotrophic factor enhances the expression of the monocarboxylate transporter 2 through translational activation in mouse cultured cortical neurons. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 30. issue 2. 2010-03-02. PMID:19794395. |
brain-derived neurotrophic factor (bdnf), a promoter of synaptic plasticity, significantly increased mct2 protein expression in cultured cortical neurons (as shown by immunocytochemistry and western blot) through a translational regulation at the synaptic level. |
2010-03-02 |
2023-08-12 |
mouse |
Camille Robinet, Luc Pelleri. Brain-derived neurotrophic factor enhances the expression of the monocarboxylate transporter 2 through translational activation in mouse cultured cortical neurons. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 30. issue 2. 2010-03-02. PMID:19794395. |
moreover, our observations suggest that changes in mct2 expression could participate in the process of synaptic plasticity induced by bdnf. |
2010-03-02 |
2023-08-12 |
mouse |
Matylda Macias, Dorota Nowicka, Artur Czupryn, Dorota Sulejczak, Małgorzata Skup, Jolanta Skangiel-Kramska, Julita Czarkowska-Bauc. Exercise-induced motor improvement after complete spinal cord transection and its relation to expression of brain-derived neurotrophic factor and presynaptic markers. BMC neuroscience. vol 10. 2010-02-12. PMID:19961582. |
the questions arise: (i) how the treadmill locomotor training, supplemented with tail stimulation, affects the expression of molecular correlates of synaptic plasticity in spinal rats, and (ii) if a response is related to bdnf protein level and distribution. |
2010-02-12 |
2023-08-12 |
rat |
Moriah E Thomason, Daniel J Yoo, Gary H Glover, Ian H Gotli. BDNF genotype modulates resting functional connectivity in children. Frontiers in human neuroscience. vol 3. 2009-12-16. PMID:19956404. |
here we show that the bdnf gene, known to regulate synaptic plasticity and connectivity in the brain, affects functional connectivity at the neural systems level. |
2009-12-16 |
2023-08-12 |
Not clear |
Emily G Waterhouse, Baoji X. New insights into the role of brain-derived neurotrophic factor in synaptic plasticity. Molecular and cellular neurosciences. vol 42. issue 2. 2009-12-14. PMID:19577647. |
substantial evidence indicates that brain-derived neurotrophic factor (bdnf) plays a crucial role in synaptic plasticity. |
2009-12-14 |
2023-08-12 |
Not clear |
Elaine K Y Chung, Zhao-Xiang Bian, Hong-Xi Xu, Joseph Jao-Yiu Sun. Neonatal maternal separation increases brain-derived neurotrophic factor and tyrosine kinase receptor B expression in the descending pain modulatory system. Neuro-Signals. vol 17. issue 3. 2009-11-13. PMID:19546592. |
brain-derived neurotrophic factor (bdnf) not only has an important role in long-term synaptic plasticity but also in facilitating descending pain. |
2009-11-13 |
2023-08-12 |
rat |
Sraboni Chaudhury, Shashi Wadhw. Prenatal auditory stimulation alters the levels of CREB mRNA, p-CREB and BDNF expression in chick hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 27. issue 6. 2009-11-13. PMID:19559781. |
further, the increased levels of bdnf may also help in regulating synaptic plasticity. |
2009-11-13 |
2023-08-12 |
chicken |
Mai Marie Holm, Jose Luis Nieto-Gonzalez, Irina Vardya, Christian Bjerggaard Vaegter, Anders Nykjaer, Kimmo Jense. Mature BDNF, but not proBDNF, reduces excitability of fast-spiking interneurons in mouse dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 40. 2009-11-10. PMID:19812317. |
mature bdnf and its precursor probdnf may both be secreted to exert opposite effects on synaptic plasticity in the hippocampus. |
2009-11-10 |
2023-08-12 |
mouse |
Michael E Greenberg, Baoji Xu, Bai Lu, Barbara L Hempstea. New insights in the biology of BDNF synthesis and release: implications in CNS function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 41. 2009-10-30. PMID:19828787. |
bdnf has pleiotropic effects on neuronal development and synaptic plasticity that underlie circuit formation and cognitive function. |
2009-10-30 |
2023-08-12 |
Not clear |
Alyssa Arentoft, Victoria Sweat, Vanessa Starr, Stephen Oliver, Jason Hassenstab, Hannah Bruehl, Aziz Tirsi, Elizabeth Javier, Pauline F McHugh, Antonio Convi. Plasma BDNF is reduced among middle-aged and elderly women with impaired insulin function: evidence of a compensatory mechanism. Brain and cognition. vol 71. issue 2. 2009-10-15. PMID:19481324. |
brain-derived neurotrophic factor (bdnf) plays a regulatory role in neuronal differentiation and synaptic plasticity and has been linked to glucose regulation and cognition. |
2009-10-15 |
2023-08-12 |
human |
Yun Wang, Jin-Shun Qi, Shuzhen Kong, Yajie Sun, Jing Fan, Min Jiang, Gong Che. BDNF-TrkB signaling pathway mediates the induction of epileptiform activity induced by a convulsant drug cyclothiazide. Neuropharmacology. vol 57. issue 1. 2009-10-01. PMID:19393251. |
brain-derived neurotrophic factor (bdnf) and its receptor trkb play an important function in neuronal development and synaptic plasticity. |
2009-10-01 |
2023-08-12 |
rat |
Clarissa M Comim, Lisiane Tuon, Laura Stertz, Mariz Vainzof, Flávio Kapczinski, João Queved. Striatum brain-derived neurotrophic factor levels are decreased in dystrophin-deficient mice. Neuroscience letters. vol 459. issue 2. 2009-09-14. PMID:19422882. |
the brain-derived neurotrophic factor (bdnf) is a regulator of neuronal survival, fast synaptic transmission, and activity-dependent synaptic plasticity. |
2009-09-14 |
2023-08-12 |
mouse |
Volkmar Lessmann, Tanja Brigadsk. Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update. Neuroscience research. vol 65. issue 1. 2009-09-03. PMID:19523993. |
brain-derived neurotrophic factor (bdnf) and other members of the protein family of neurotrophins have been implicated in a multitude of processes that are important for neuronal development and synaptic plasticity in the rodent central nervous system. |
2009-09-03 |
2023-08-12 |
Not clear |
Tsan-Ju Chen, Dean-Chuan Wang, Shun-Sheng Che. Amyloid-beta interrupts the PI3K-Akt-mTOR signaling pathway that could be involved in brain-derived neurotrophic factor-induced Arc expression in rat cortical neurons. Journal of neuroscience research. vol 87. issue 10. 2009-08-31. PMID:19301428. |
brain-derived neurotrophic factor (bdnf) is well known to be capable of inducing the synthesis of activity-regulated cytoskeleton-associated protein (arc), which plays a fundamental role in modulating synaptic plasticity. |
2009-08-31 |
2023-08-12 |
rat |
Q Li, H F Zhao, Z F Zhang, Z G Liu, X R Pei, J B Wang, M Y Cai, Y L. Long-term administration of green tea catechins prevents age-related spatial learning and memory decline in C57BL/6 J mice by regulating hippocampal cyclic amp-response element binding protein signaling cascade. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19409206. |
the expressions of brain-derived neurotrophic factor (bdnf) and bcl-2, two target genes of creb which can exhibit long-term regulatory roles in synaptic plasticity and synaptic structure, were also increased. |
2009-08-20 |
2023-08-12 |
mouse |
Ge Li, Elaine R Peskind, Steven P Millard, Peter Chi, Izabela Sokal, Chang-En Yu, Lynn M Bekris, Murray A Raskind, Douglas R Galasko, Thomas J Montin. Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects. PloS one. vol 4. issue 5. 2009-08-17. PMID:19412541. |
brain-derived neurotrophic factor (bdnf) is an activity-dependent secreted protein that is critical to organization of neuronal networks and synaptic plasticity, especially in the hippocampus. |
2009-08-17 |
2023-08-12 |
human |
Shiyong Peng, Diego J Garzon, Monica Marchese, William Klein, Stephen D Ginsberg, Beverly M Francis, Howard T J Mount, Elliott J Mufson, Ahmad Salehi, Margaret Fahnestoc. Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 29. 2009-08-10. PMID:19625522. |
since bdnf plays a critical role in neuronal survival, synaptic plasticity, and memory, bdnf reduction may contribute to synaptic and cellular loss and memory deficits characteristic of ad. |
2009-08-10 |
2023-08-12 |
mouse |
Jie Leng, Li Jiang, Hengsheng Chen, Xiaoping Zhan. Brain-derived neurotrophic factor and electrophysiological properties of voltage-gated ion channels during neuronal stem cell development. Brain research. vol 1272. 2009-08-07. PMID:19344696. |
brain-derived neurotrophic factor (bdnf) has been reported to play a critical role in modulating a variety of neural functions such as membrane excitability, synaptic transmission, and activity-dependent synaptic plasticity. |
2009-08-07 |
2023-08-12 |
Not clear |
Hussam Jourdi, Yu-Tien Hsu, Miou Zhou, Qingyu Qin, Xiaoning Bi, Michel Baudr. Positive AMPA receptor modulation rapidly stimulates BDNF release and increases dendritic mRNA translation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 27. 2009-08-03. PMID:19587275. |
they also suggest that increased bdnf secretion and stimulation of local protein synthesis contribute to the effects of ampakines on synaptic plasticity. |
2009-08-03 |
2023-08-12 |
Not clear |