Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yun Wang, Jin-Shun Qi, Shuzhen Kong, Yajie Sun, Jing Fan, Min Jiang, Gong Che. BDNF-TrkB signaling pathway mediates the induction of epileptiform activity induced by a convulsant drug cyclothiazide. Neuropharmacology. vol 57. issue 1. 2009-10-01. PMID:19393251. |
brain-derived neurotrophic factor (bdnf) and its receptor trkb play an important function in neuronal development and synaptic plasticity. |
2009-10-01 |
2023-08-12 |
rat |
Clarissa M Comim, Lisiane Tuon, Laura Stertz, Mariz Vainzof, Flávio Kapczinski, João Queved. Striatum brain-derived neurotrophic factor levels are decreased in dystrophin-deficient mice. Neuroscience letters. vol 459. issue 2. 2009-09-14. PMID:19422882. |
the brain-derived neurotrophic factor (bdnf) is a regulator of neuronal survival, fast synaptic transmission, and activity-dependent synaptic plasticity. |
2009-09-14 |
2023-08-12 |
mouse |
Volkmar Lessmann, Tanja Brigadsk. Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update. Neuroscience research. vol 65. issue 1. 2009-09-03. PMID:19523993. |
brain-derived neurotrophic factor (bdnf) and other members of the protein family of neurotrophins have been implicated in a multitude of processes that are important for neuronal development and synaptic plasticity in the rodent central nervous system. |
2009-09-03 |
2023-08-12 |
Not clear |
Tsan-Ju Chen, Dean-Chuan Wang, Shun-Sheng Che. Amyloid-beta interrupts the PI3K-Akt-mTOR signaling pathway that could be involved in brain-derived neurotrophic factor-induced Arc expression in rat cortical neurons. Journal of neuroscience research. vol 87. issue 10. 2009-08-31. PMID:19301428. |
brain-derived neurotrophic factor (bdnf) is well known to be capable of inducing the synthesis of activity-regulated cytoskeleton-associated protein (arc), which plays a fundamental role in modulating synaptic plasticity. |
2009-08-31 |
2023-08-12 |
rat |
Q Li, H F Zhao, Z F Zhang, Z G Liu, X R Pei, J B Wang, M Y Cai, Y L. Long-term administration of green tea catechins prevents age-related spatial learning and memory decline in C57BL/6 J mice by regulating hippocampal cyclic amp-response element binding protein signaling cascade. Neuroscience. vol 159. issue 4. 2009-08-20. PMID:19409206. |
the expressions of brain-derived neurotrophic factor (bdnf) and bcl-2, two target genes of creb which can exhibit long-term regulatory roles in synaptic plasticity and synaptic structure, were also increased. |
2009-08-20 |
2023-08-12 |
mouse |
Ge Li, Elaine R Peskind, Steven P Millard, Peter Chi, Izabela Sokal, Chang-En Yu, Lynn M Bekris, Murray A Raskind, Douglas R Galasko, Thomas J Montin. Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects. PloS one. vol 4. issue 5. 2009-08-17. PMID:19412541. |
brain-derived neurotrophic factor (bdnf) is an activity-dependent secreted protein that is critical to organization of neuronal networks and synaptic plasticity, especially in the hippocampus. |
2009-08-17 |
2023-08-12 |
human |
Shiyong Peng, Diego J Garzon, Monica Marchese, William Klein, Stephen D Ginsberg, Beverly M Francis, Howard T J Mount, Elliott J Mufson, Ahmad Salehi, Margaret Fahnestoc. Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 29. 2009-08-10. PMID:19625522. |
since bdnf plays a critical role in neuronal survival, synaptic plasticity, and memory, bdnf reduction may contribute to synaptic and cellular loss and memory deficits characteristic of ad. |
2009-08-10 |
2023-08-12 |
mouse |
Jie Leng, Li Jiang, Hengsheng Chen, Xiaoping Zhan. Brain-derived neurotrophic factor and electrophysiological properties of voltage-gated ion channels during neuronal stem cell development. Brain research. vol 1272. 2009-08-07. PMID:19344696. |
brain-derived neurotrophic factor (bdnf) has been reported to play a critical role in modulating a variety of neural functions such as membrane excitability, synaptic transmission, and activity-dependent synaptic plasticity. |
2009-08-07 |
2023-08-12 |
Not clear |
Hussam Jourdi, Yu-Tien Hsu, Miou Zhou, Qingyu Qin, Xiaoning Bi, Michel Baudr. Positive AMPA receptor modulation rapidly stimulates BDNF release and increases dendritic mRNA translation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 27. 2009-08-03. PMID:19587275. |
they also suggest that increased bdnf secretion and stimulation of local protein synthesis contribute to the effects of ampakines on synaptic plasticity. |
2009-08-03 |
2023-08-12 |
Not clear |
Tetsu Yamamoto, Akihiko Hirayama, Nobuo Hosoe, Masaru Furube, Shusuke Hiran. Effects of soft-diet feeding on BDNF expression in hippocampus of mice. The Bulletin of Tokyo Dental College. vol 49. issue 4. 2009-05-18. PMID:19420879. |
these results indicate that insufficient mastication activity during development reduces bdnf protein levels in the hippocampus and influences synaptic plasticity in this region. |
2009-05-18 |
2023-08-12 |
mouse |
Kazuko Sakata, Newton H Woo, Keri Martinowich, Joshua S Greene, Robert J Schloesser, Liya Shen, Bai L. Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 14. 2009-05-06. PMID:19293383. |
critical role of promoter iv-driven bdnf transcription in gabaergic transmission and synaptic plasticity in the prefrontal cortex. |
2009-05-06 |
2023-08-12 |
mouse |
Michelle Ploughman, Victoria Windle, Crystal L MacLellan, Nicole White, Jules J Doré, Dale Corbet. Brain-derived neurotrophic factor contributes to recovery of skilled reaching after focal ischemia in rats. Stroke. vol 40. issue 4. 2009-04-24. PMID:19164786. |
brain-derived neurotrophic factor (bdnf) is involved in neuronal survival, synaptic plasticity, learning and memory, and neuroplasticity. |
2009-04-24 |
2023-08-12 |
rat |
Robert A Crozier, Caixia Bi, Yu R Han, Mark R Plumme. BDNF modulation of NMDA receptors is activity dependent. Journal of neurophysiology. vol 100. issue 6. 2009-04-23. PMID:18842955. |
brain-derived neurotrophic factor (bdnf), a potent modulator of synaptic transmission, is known to influence associative synaptic plasticity and refinement of neural connectivity. |
2009-04-23 |
2023-08-12 |
Not clear |
Andrea Gómez-Palacio-Schjetnan, Martha L Escoba. In vivo BDNF modulation of adult functional and morphological synaptic plasticity at hippocampal mossy fibers. Neuroscience letters. vol 445. issue 1. 2009-04-14. PMID:18782600. |
in vivo bdnf modulation of adult functional and morphological synaptic plasticity at hippocampal mossy fibers. |
2009-04-14 |
2023-08-12 |
rat |
Andrea Gómez-Palacio-Schjetnan, Martha L Escoba. In vivo BDNF modulation of adult functional and morphological synaptic plasticity at hippocampal mossy fibers. Neuroscience letters. vol 445. issue 1. 2009-04-14. PMID:18782600. |
these findings support the idea that bdnf plays an important role as synaptic messenger of activity-dependent synaptic plasticity in the adult mammalian brain, in vivo. |
2009-04-14 |
2023-08-12 |
rat |
F Miyajima, J P Quinn, M Horan, A Pickles, W E Ollier, N Pendleton, A Payto. Additive effect of BDNF and REST polymorphisms is associated with improved general cognitive ability. Genes, brain, and behavior. vol 7. issue 7. 2009-04-10. PMID:18518926. |
brain-derived neurotrophic factor (bdnf) is a pleiotropic protein involved in neuronal proliferation, differentiation, synaptic plasticity and survival. |
2009-04-10 |
2023-08-12 |
human |
S Yasuda, M-H Liang, Z Marinova, A Yahyavi, D-M Chuan. The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons. Molecular psychiatry. vol 14. issue 1. 2009-04-08. PMID:17925795. |
brain-derived neurotrophic factor (bdnf) has been strongly implicated in the synaptic plasticity, neuronal survival and pathophysiology of depression. |
2009-04-08 |
2023-08-12 |
rat |
Danielle A Simmons, Christopher S Rex, Linda Palmer, Vijay Pandyarajan, Vadim Fedulov, Christine M Gall, Gary Lync. Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 12. 2009-04-08. PMID:19264961. |
up-regulating bdnf with an ampakine rescues synaptic plasticity and memory in huntington's disease knockin mice. |
2009-04-08 |
2023-08-12 |
mouse |
Nicola Kuczewski, Christophe Porcher, Volkmar Lessmann, Igor Medina, Jean-Luc Gaiars. Activity-dependent dendritic release of BDNF and biological consequences. Molecular neurobiology. vol 39. issue 1. 2009-03-30. PMID:19156544. |
in this paper, we provide an overview of recent findings showing that bdnf can serve as a target-derived messenger for activity-dependent synaptic plasticity and development at the single cell level. |
2009-03-30 |
2023-08-12 |
Not clear |
Rafaela Chitarra Rodrigues Hell, Miriam Maria Silva Costa, Alfredo Miranda Goes, Alexandre L R Oliveir. Local injection of BDNF producing mesenchymal stem cells increases neuronal survival and synaptic stability following ventral root avulsion. Neurobiology of disease. vol 33. issue 2. 2009-03-09. PMID:19049875. |
thus it was proposed that when maintained undifferentiated for a period of 10 weeks, mscs may be used as a continuous source of bdnf, positively influencing neuronal survival and synaptic plasticity. |
2009-03-09 |
2023-08-12 |
rat |