Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Frank Krueger, Matteo Pardini, Edward D Huey, Vanessa Raymont, Jeffrey Solomon, Robert H Lipsky, Colin A Hodgkinson, David Goldman, Jordan Grafma. The role of the Met66 brain-derived neurotrophic factor allele in the recovery of executive functioning after combat-related traumatic brain injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 2. 2011-02-22. PMID:21228168. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophin family, promotes survival and synaptic plasticity in the human brain. |
2011-02-22 |
2023-08-12 |
human |
Nicola Kuczewski, Christophe Porcher, Jean-Luc Gaiars. Activity-dependent dendritic secretion of brain-derived neurotrophic factor modulates synaptic plasticity. The European journal of neuroscience. vol 32. issue 8. 2011-01-28. PMID:20880359. |
although the importance of bdnf in synaptic plasticity has been clearly established, direct evidence for a specific contribution of the activity-dependent dendritic secretion of bdnf has been difficult to obtain. |
2011-01-28 |
2023-08-12 |
Not clear |
Tsan-Ju Chen, Hsiu-Min Cheng, Dean-Chuan Wang, Hui-Shan Hun. Nonlethal aluminum maltolate can reduce brain-derived neurotrophic factor-induced Arc expression through interrupting the ERK signaling in SH-SY5Y neuroblastoma cells. Toxicology letters. vol 200. issue 1-2. 2011-01-18. PMID:21040763. |
in particular, activity-regulated cytoskeleton-associated protein (arc) has a versatile role in synaptic plasticity, and its synthesis can be induced by brain-derived neurotrophic factor (bdnf). |
2011-01-18 |
2023-08-12 |
human |
Silvia Alboni, Cristina Benatti, Giacomo Capone, Daniela Corsini, Federica Caggia, Fabio Tascedda, Julien Mendlewicz, Nicoletta Brunell. Time-dependent effects of escitalopram on brain derived neurotrophic factor (BDNF) and neuroplasticity related targets in the central nervous system of rats. European journal of pharmacology. vol 643. issue 2-3. 2010-12-28. PMID:20599917. |
escitalopram, known to be already effective in preclinical models of depression after 7 days, allowed us to investigate whether two effective treatment regimens (7 and 21 days) may contribute to synaptic plasticity by acting on bdnf signalling. |
2010-12-28 |
2023-08-12 |
rat |
Silvia Alboni, Cristina Benatti, Giacomo Capone, Daniela Corsini, Federica Caggia, Fabio Tascedda, Julien Mendlewicz, Nicoletta Brunell. Time-dependent effects of escitalopram on brain derived neurotrophic factor (BDNF) and neuroplasticity related targets in the central nervous system of rats. European journal of pharmacology. vol 643. issue 2-3. 2010-12-28. PMID:20599917. |
we focused our attention on two regulators of bdnf transcription, creb and carf (calcium responsive factor), and on kinases, camkii, erk1/2 and p38 mapk, linked to bdnf that play a distinctive role in synaptic plasticity. |
2010-12-28 |
2023-08-12 |
rat |
A Terracciano, B Martin, D Ansari, T Tanaka, L Ferrucci, S Maudsley, M P Mattson, P T Cost. Plasma BDNF concentration, Val66Met genetic variant and depression-related personality traits. Genes, brain, and behavior. vol 9. issue 5. 2010-11-15. PMID:20345896. |
brain-derived neurotrophic factor (bdnf) regulates synaptic plasticity and neurogenesis, and bdnf plasma and serum levels have been associated with depression, alzheimer's disease, and other psychiatric and neurodegenerative disorders. |
2010-11-15 |
2023-08-12 |
Not clear |
Shu-Chen Li, Christian Chicherio, Lars Nyberg, Timo von Oertzen, Irene E Nagel, Goran Papenberg, Thomas Sander, Hauke R Heekeren, Ulman Lindenberger, Lars Bäckma. Ebbinghaus revisited: influences of the BDNF Val66Met polymorphism on backward serial recall are modulated by human aging. Journal of cognitive neuroscience. vol 22. issue 10. 2010-09-22. PMID:19925205. |
the brain-derived neurotrophic factor (bdnf) plays an important role in activity-dependent synaptic plasticity, which underlies learning and memory. |
2010-09-22 |
2023-08-12 |
human |
Jun Gao, Wen-Yuan Wang, Ying-Wei Mao, Johannes Gräff, Ji-Song Guan, Ling Pan, Gloria Mak, Dohoon Kim, Susan C Su, Li-Huei Tsa. A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature. vol 466. issue 7310. 2010-09-13. PMID:20622856. |
sirt1 normally functions to limit expression of mir-134 via a repressor complex containing the transcription factor yy1, and unchecked mir-134 expression following sirt1 deficiency results in the downregulated expression of creb and brain-derived neurotrophic factor (bdnf), thereby impairing synaptic plasticity. |
2010-09-13 |
2023-08-12 |
Not clear |
Marie-Christine Pardo. Role of neurotrophic factors in behavioral processes: implications for the treatment of psychiatric and neurodegenerative disorders. Vitamins and hormones. vol 82. 2010-08-20. PMID:20472139. |
brain-derived neurotrophic factor (bdnf) has been the most widely studied neurotrophin because of its important role as modulator of synaptic plasticity, which is essential to the regulation of experience-dependent behavior. |
2010-08-20 |
2023-08-12 |
Not clear |
Midori Ninomiya, Tadahiro Numakawa, Naoki Adachi, Miyako Furuta, Shuichi Chiba, Misty Richards, Shigenobu Shibata, Hiroshi Kunug. Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20398734. |
brain-derived neurotrophic factor (bdnf), which plays a role in neuronal survival and synaptic plasticity in the central nervous system (cns), may also be associated with schizophrenia. |
2010-07-30 |
2023-08-12 |
rat |
Ipe Ninan, Kevin G Bath, Karishma Dagar, Rosalia Perez-Castro, Mark R Plummer, Francis S Lee, Moses V Cha. The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592208. |
the bdnf val66met polymorphism impairs nmda receptor-dependent synaptic plasticity in the hippocampus. |
2010-07-22 |
2023-08-12 |
mouse |
Ipe Ninan, Kevin G Bath, Karishma Dagar, Rosalia Perez-Castro, Mark R Plummer, Francis S Lee, Moses V Cha. The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592208. |
consistent with the nmda receptor-dependent synaptic plasticity impairment, we observed a significant decrease in nmda receptor neurotransmission in the ca1 pyramidal neurons of bdnf(met/met) mice. |
2010-07-22 |
2023-08-12 |
mouse |
Ipe Ninan, Kevin G Bath, Karishma Dagar, Rosalia Perez-Castro, Mark R Plummer, Francis S Lee, Moses V Cha. The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592208. |
thus, these results show that the bdnf val66met polymorphism has a direct effect on nmda receptor transmission, which may account for changes in synaptic plasticity in the hippocampus. |
2010-07-22 |
2023-08-12 |
mouse |
Dao-Yao He, Jérémie Neasta, Dorit Ro. Epigenetic regulation of BDNF expression via the scaffolding protein RACK1. The Journal of biological chemistry. vol 285. issue 25. 2010-07-21. PMID:20410295. |
furthermore, this novel mechanism for the regulation of exon-specific expression of the bdnf gene by rack1 could have implications on the neuronal functions of the growth factor including synaptic plasticity, learning, and memory. |
2010-07-21 |
2023-08-12 |
Not clear |
Fei Wang, Xin Geng, Hua-Ying Tao, Yan Chen. The restoration after repetitive transcranial magnetic stimulation treatment on cognitive ability of vascular dementia rats and its impacts on synaptic plasticity in hippocampal CA1 area. Journal of molecular neuroscience : MN. vol 41. issue 1. 2010-07-12. PMID:19953343. |
rtms plays an important and beneficial role in the restoration treatment of vascular dementia, which may be related to the mechanism that rtms can increase the mrna and protein expressions of bdnf, nmdar1, and syn and affect the synaptic plasticity in hippocampal ca1 area. |
2010-07-12 |
2023-08-12 |
rat |
Veronica Ghiglieri, Carmelo Sgobio, Stefano Patassini, Vincenza Bagetta, Anna Fejtova, Carmela Giampà, Silvia Marinucci, Alexandra Heyden, Eckart D Gundelfinger, Francesca R Fusco, Paolo Calabresi, Barbara Piccon. TrkB/BDNF-dependent striatal plasticity and behavior in a genetic model of epilepsy: modulation by valproic acid. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 7. 2010-07-09. PMID:20200504. |
brain-derived neurotrophic factor (bdnf) is a key factor for the induction and maintenance of synaptic plasticity and it is also implicated in the mechanisms underlying epilepsy-induced adaptive changes. |
2010-07-09 |
2023-08-12 |
mouse |
Lisete Haas, Luis V C Portela, Ana Elisa Böhmer, Jean Pierre Oses, Diogo R Lar. Increased plasma levels of brain derived neurotrophic factor (BDNF) in patients with fibromyalgia. Neurochemical research. vol 35. issue 5. 2010-07-08. PMID:20119637. |
brain-derived neurotrophic factor (bdnf) is involved in neuronal survival and synaptic plasticity of the central and peripheral nervous system. |
2010-07-08 |
2023-08-12 |
human |
S Fanous, R P Hammer, E M Nikulin. Short- and long-term effects of intermittent social defeat stress on brain-derived neurotrophic factor expression in mesocorticolimbic brain regions. Neuroscience. vol 167. issue 3. 2010-06-29. PMID:20206238. |
a potential candidate for mediating these effects is brain-derived neurotrophic factor (bdnf), a neurotrophin involved in synaptic plasticity and displaying alterations in dopaminergic regions in response to various types of stress. |
2010-06-29 |
2023-08-12 |
rat |
Tina B Lonsdorf, Almut I Weike, Armita Golkar, Martin Schalling, Alfons O Hamm, Arne Öhma. Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism. Behavioral neuroscience. vol 124. issue 1. 2010-06-28. PMID:20141276. |
we suggest that the bdnf met-allele may have a protective effect for the development of affective pathologies that may be mediated via reduced synaptic plasticity induced by negative experience. |
2010-06-28 |
2023-08-12 |
human |
John Kealy, Sean Commin. Frequency-dependent changes in synaptic plasticity and brain-derived neurotrophic factor (BDNF) expression in the CA1 to perirhinal cortex projection. Brain research. vol 1326. 2010-06-25. PMID:20193668. |
frequency-dependent changes in synaptic plasticity and brain-derived neurotrophic factor (bdnf) expression in the ca1 to perirhinal cortex projection. |
2010-06-25 |
2023-08-12 |
Not clear |