| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Grabiele Musumeci, Liliana Minichiell. BDNF-TrkB signalling in fear learning: from genetics to neural networks. Reviews in the neurosciences. vol 22. issue 3. 2011-08-23. PMID:21639804. |
among the molecular systems required for fear learning and amygdalar synaptic plasticity, brain derived neurtrophic factor (bdnf) and its high affinity receptor ntrk2/trkb have been shown to play essential roles. |
2011-08-23 |
2023-08-12 |
Not clear |
| Valerio Ricci, Giovanni Martinotti, Francesca Gelfo, Federico Tonioni, Carlo Caltagirone, Pietro Bria, Francesco Angelucc. Chronic ketamine use increases serum levels of brain-derived neurotrophic factor. Psychopharmacology. vol 215. issue 1. 2011-08-15. PMID:21161184. |
in addition, neurotrophins, particularly bdnf, may regulate ltp in the hippocampus and influence synaptic plasticity. |
2011-08-15 |
2023-08-12 |
Not clear |
| Tanja Richter-Schmidinger, Panagiotis Alexopoulos, Marco Horn, Sebastian Maus, Martin Reichel, Cosima Rhein, Piotr Lewczuk, Christos Sidiropoulos, Thomas Kneib, Robert Perneczky, Arnd Doerfler, Johannes Kornhube. Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults. Journal of neural transmission (Vienna, Austria : 1996). vol 118. issue 2. 2011-08-12. PMID:21190051. |
apolipoprotein e (apoe) and brain-derived neurotrophic factor (bdnf) play an important role in cell growth, regeneration, synaptic plasticity, learning and memory processes. |
2011-08-12 |
2023-08-12 |
Not clear |
| Homeira Hatami, Mohammad Ali Hossainpour-Faizi, Maryam Azarfarin, Parvin Azarfa. Chronic ecstasy use increases neurotrophin-4 gene expression and protein levels in the rat brain. Pharmacological reports : PR. vol 62. issue 6. 2011-08-10. PMID:21273656. |
the molecular basis of addiction remains poorly understood, but diverse lines of evidence suggest that neurotrophins (bdnf, nt-3 and nt-4) play a role in the regulation of synaptic plasticity. |
2011-08-10 |
2023-08-12 |
rat |
| Fernando Gomez-Pinilla, Zhe Ying, Teodora Agoncillo, Ron Frosti. The influence of naturalistic experience on plasticity markers in somatosensory cortex and hippocampus: effects of whisker use. Brain research. vol 1388. 2011-08-08. PMID:21385568. |
based on the role of bdnf on synaptic plasticity and neuronal growth, the focus of this study is on bdnf and its downstream effectors creb, synapsin i, and gap-43. |
2011-08-08 |
2023-08-12 |
rat |
| Joanna L Spencer-Segal, Elizabeth M Waters, Kevin G Bath, Moses V Chao, Bruce S McEwen, Teresa A Milne. Distribution of phosphorylated TrkB receptor in the mouse hippocampal formation depends on sex and estrous cycle stage. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 18. 2011-08-05. PMID:21543608. |
using electron microscopy, we localized trkb phosphorylated at tyrosine 816 (ptrkb) in the hippocampal formation of male and female mice under conditions of naturally low circulating estradiol and naturally high circulating estradiol, when bdnf expression, trkb signaling, and synaptic plasticity are enhanced. |
2011-08-05 |
2023-08-12 |
mouse |
| E Bałkowiec-Iskra, A Vermehren-Schmaedick, A Balkowie. Tumor necrosis factor-α increases brain-derived neurotrophic factor expression in trigeminal ganglion neurons in an activity-dependent manner. Neuroscience. vol 180. 2011-08-04. PMID:21335064. |
in the present study, we examined the effects of tnfα on neuronal expression of brain-derived neurotrophic factor (bdnf), whose role in synaptic plasticity and sensitization of nociceptive pathways is well documented. |
2011-08-04 |
2023-08-12 |
rat |
| Carla Cunha, Riccardo Brambilla, Kerrie L Thoma. A simple role for BDNF in learning and memory? Frontiers in molecular neuroscience. vol 3. 2011-07-14. PMID:20162032. |
more recently, bdnf has also emerged as an important regulator of synaptogenesis and synaptic plasticity mechanisms underlying learning and memory in the adult cns. |
2011-07-14 |
2023-08-12 |
human |
| Carla Cunha, Riccardo Brambilla, Kerrie L Thoma. A simple role for BDNF in learning and memory? Frontiers in molecular neuroscience. vol 3. 2011-07-14. PMID:20162032. |
in this review we will discuss our knowledge about the multiple intracellular signalling pathways activated by bdnf, and the role of this neurotrophin in long-term synaptic plasticity and memory formation as well as in synaptogenesis. |
2011-07-14 |
2023-08-12 |
human |
| Carla Cunha, Riccardo Brambilla, Kerrie L Thoma. A simple role for BDNF in learning and memory? Frontiers in molecular neuroscience. vol 3. 2011-07-14. PMID:20162032. |
we will show that maturation of bdnf, its cellular localization and its ability to regulate both excitatory and inhibitory synapses in the cns may result in conflicting alterations in synaptic plasticity and memory formation. |
2011-07-14 |
2023-08-12 |
human |
| Tadahiro Numakawa, Daisaku Yokomaku, Misty Richards, Hiroaki Hori, Naoki Adachi, Hiroshi Kunug. Functional interactions between steroid hormones and neurotrophin BDNF. World journal of biological chemistry. vol 1. issue 5. 2011-07-14. PMID:21540998. |
brain-derived neurotrophic factor (bdnf), a critical neurotrophin, regulates many neuronal aspects including cell differentiation, cell survival, neurotransmission, and synaptic plasticity in the central nervous system (cns). |
2011-07-14 |
2023-08-12 |
Not clear |
| H A Boger, P Mannangatti, D J Samuvel, A J Saylor, T S Bender, J F McGinty, A M Fortress, V Zaman, P Huang, L D Middaugh, P K Randall, L D Jayanthi, B Rohrer, K L Helke, A-C Granholm, S Ramamoorth. Effects of brain-derived neurotrophic factor on dopaminergic function and motor behavior during aging. Genes, brain, and behavior. vol 10. issue 2. 2011-06-15. PMID:20860702. |
brain-derived neurotrophic factor (bdnf) is critical in synaptic plasticity and in the survival and function of midbrain dopamine neurons. |
2011-06-15 |
2023-08-12 |
mouse |
| Giuseppe P Cortese, Ruth M Barrientos, Steven F Maier, Susan L Patterso. Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411668. |
interestingly, these deficits occur in forms of long-term memory and synaptic plasticity known to be strongly dependent on brain-derived neurotrophic factor (bdnf). |
2011-06-15 |
2023-08-12 |
rat |
| Giuseppe P Cortese, Ruth M Barrientos, Steven F Maier, Susan L Patterso. Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411668. |
these data suggest that inflammation-evoked reductions in bdnf at synapses might contribute to inflammation-evoked disruptions in long-term memory and synaptic plasticity in aging. |
2011-06-15 |
2023-08-12 |
rat |
| Chiara Cazzin, Silvia Mion, Fabrizio Caldara, Joseph M Rimland, Enrico Domenic. Microarray analysis of cultured rat hippocampal neurons treated with brain derived neurotrophic factor. Molecular biology reports. vol 38. issue 2. 2011-05-26. PMID:20535563. |
more studies are needed to investigate and confirm the role of these genes in synaptic plasticity, but the results reported in this paper show that microarray analysis of hippocampal cultures can be used to expand our current knowledge of the molecular events triggered by bdnf in the hippocampus. |
2011-05-26 |
2023-08-12 |
rat |
| Hui-li Liu, Gang Zhao, Kui Cai, Hai-hua Zhao, Li-de Sh. Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation. Behavioural brain research. vol 218. issue 2. 2011-05-06. PMID:21192984. |
however, bdnf has emerged as a crucial regulator of synaptic plasticity mechanisms underlying learning and memory in wild-type mice, but not in app/ps1 mice. |
2011-05-06 |
2023-08-12 |
mouse |
| Yogesh Dwived. Brain-derived neurotrophic factor: role in depression and suicide. Neuropsychiatric disease and treatment. vol 5. 2011-04-26. PMID:19721723. |
brain-derived neurotrophic factor (bdnf), one of the major neurotrophic factors, plays an important role in the maintenance and survival of neurons and in synaptic plasticity. |
2011-04-26 |
2023-08-12 |
Not clear |
| Hui Yu, Zhe-yu Che. The role of BDNF in depression on the basis of its location in the neural circuitry. Acta pharmacologica Sinica. vol 32. issue 1. 2011-04-25. PMID:21131999. |
brain-derived neurotrophic factor (bdnf) is broadly expressed in the developing and adult mammalian brain and has been implicated in development, neural regeneration, synaptic transmission, synaptic plasticity and neurogenesis. |
2011-04-25 |
2023-08-12 |
Not clear |
| Yen-Ching Wu, Rebecca Williamson, Zhi Li, Annalisa Vicario, Jerry Xu, Masataka Kasai, Yijuang Chern, Enrico Tongiorgi, Jay M Baraba. Dendritic trafficking of brain-derived neurotrophic factor mRNA: regulation by translin-dependent and -independent mechanisms. Journal of neurochemistry. vol 116. issue 6. 2011-04-15. PMID:21198640. |
dendritic trafficking and translation of brain-derived neurotrophic factor (bdnf) transcripts play a key role in mediating synaptic plasticity. |
2011-04-15 |
2023-08-12 |
mouse |
| Tatiana Adasme, Paola Haeger, Andrea C Paula-Lima, Italo Espinoza, M Mercedes Casas-Alarcón, M Angélica Carrasco, Cecilia Hidalg. Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 7. 2011-04-14. PMID:21282625. |
along with calcium signals, brain-derived neurotrophic factor (bdnf) is a key signaling molecule for hippocampal synaptic plasticity and spatial memory. |
2011-04-14 |
2023-08-12 |
rat |