Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Zonggang Hou, Wei Luo, Xuejun Sun, Shuyu Hao, Ying Zhang, Feifan Xu, Zhongcheng Wang, Baiyun Li. Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury. Brain research bulletin. vol 88. issue 6. 2012-11-23. PMID:22742936. |
in addition, treatment with hydrogen-rich saline, which elevated the levels of molecules associated with brain-derived neurotropic factor (bdnf)-mediated synaptic plasticity, improved cognitive performance in the morris water maze after mild tbi. |
2012-11-23 |
2023-08-12 |
rat |
R Andero, K J Ressle. Fear extinction and BDNF: translating animal models of PTSD to the clinic. Genes, brain, and behavior. vol 11. issue 5. 2012-11-20. PMID:22530815. |
brain-derived neurotrophic factor (bdnf) is the most studied neurotrophin involved in synaptic plasticity processes that are required for long-term learning and memory. |
2012-11-20 |
2023-08-12 |
Not clear |
R Andero, K J Ressle. Fear extinction and BDNF: translating animal models of PTSD to the clinic. Genes, brain, and behavior. vol 11. issue 5. 2012-11-20. PMID:22530815. |
the aim of this review is to provide a translational point of view that stems from findings in the bdnf regulation of synaptic plasticity and fear extinction. |
2012-11-20 |
2023-08-12 |
Not clear |
Michelle D Amaral, Lucas Pozzo-Mille. Intracellular Ca2+ stores and Ca2+ influx are both required for BDNF to rapidly increase quantal vesicular transmitter release. Neural plasticity. vol 2012. 2012-11-20. PMID:22811938. |
brain-derived neurotrophic factor (bdnf) is well known as a survival factor during brain development as well as a regulator of adult synaptic plasticity. |
2012-11-20 |
2023-08-12 |
Not clear |
Clarissa M Comim, Patrícia A Reis, Valber S Frutuoso, Gabriel R Fries, Daiane B Fraga, Flávio Kapczinski, Alexandra I Zugno, Tatiana Barichello, João Quevedo, Hugo C Castro-Faria-Net. Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice. Neuroscience letters. vol 523. issue 2. 2012-11-13. PMID:22750161. |
the brain-derived neurotrophic factor (bdnf) appears to be involved with activity-dependent synaptic plasticity. |
2012-11-13 |
2023-08-12 |
mouse |
Soon-Tae Lee, Kon Chu, Keun-Hwa Jung, Jin Hee Kim, Ji-Young Huh, Hyejin Yoon, Dong-Kyu Park, Ji-Yeon Lim, Jeong-Min Kim, Daejong Jeon, Hoon Ryu, Sang Kun Lee, Manho Kim, Jae-Kyu Ro. miR-206 regulates brain-derived neurotrophic factor in Alzheimer disease model. Annals of neurology. vol 72. issue 2. 2012-11-01. PMID:22926857. |
alzheimer disease (ad) brains are deficient in brain-derived neurotrophic factor (bdnf), which regulates synaptic plasticity and memory. |
2012-11-01 |
2023-08-12 |
mouse |
Sarah M Rothman, Kathleen J Griffioen, Ruiqian Wan, Mark P Mattso. Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health. Annals of the New York Academy of Sciences. vol 1264. 2012-10-25. PMID:22548651. |
by promoting synaptic plasticity and neurogenesis in the hippocampus, bdnf mediates exercise- and der-induced improvements in cognitive function and neuroprotection. |
2012-10-25 |
2023-08-12 |
Not clear |
Haytham M Hashim, Nagy Fawzy, Mohab M Fawzi, Rehab A Kara. Brain-derived neurotrophic factor Val66Met polymorphism and obsessive-compulsive symptoms in Egyptian schizophrenia patients. Journal of psychiatric research. vol 46. issue 6. 2012-10-17. PMID:22521161. |
bdnf promote the function and growth of 5-ht neurons in the brain and modulate the synaptic plasticity of drd3-secreting neurons in the striatum, suggesting involvement of bdnf in the mediation of obsessive-compulsive disorder. |
2012-10-17 |
2023-08-12 |
Not clear |
Li Sui, Yan Wang, Li-Hua Ju, Meng Che. Epigenetic regulation of reelin and brain-derived neurotrophic factor genes in long-term potentiation in rat medial prefrontal cortex. Neurobiology of learning and memory. vol 97. issue 4. 2012-09-17. PMID:22469747. |
these findings suggest that epigenetic regulation of dna demethylation and histone acetylation of target genes, such as reelin and bdnf, might underlie the mechanisms of synaptic plasticity and memory retention in the mpfc. |
2012-09-17 |
2023-08-12 |
rat |
Sylvie Burnouf, Karim Belarbi, Laetitia Troquier, Maxime Derisbourg, Dominique Demeyer, Antoine Leboucher, Cyril Laurent, Malika Hamdane, Luc Buee, David Blu. Hippocampal BDNF expression in a tau transgenic mouse model. Current Alzheimer research. vol 9. issue 4. 2012-09-07. PMID:22272617. |
brain-derived neurotrophic factor (bdnf) is a neurotrophic factor playing a critical role in hippocampal synaptic plasticity and memory and whose levels have been shown reduced in ad brains. |
2012-09-07 |
2023-08-12 |
mouse |
Andrea Gómez-Palacio Schjetnan, Martha L Escoba. In vivo BDNF modulation of hippocampal mossy fiber plasticity induced by high frequency stimulation. Hippocampus. vol 22. issue 1. 2012-09-06. PMID:20848610. |
here we used intrahippocampal microinfusion of bdnf to analyze its effects on functional and structural synaptic plasticity induced by subsequent mossy fiber hfs sufficient to induce ltp in adult rats, in vivo. |
2012-09-06 |
2023-08-12 |
human |
Andrea Gómez-Palacio Schjetnan, Martha L Escoba. In vivo BDNF modulation of hippocampal mossy fiber plasticity induced by high frequency stimulation. Hippocampus. vol 22. issue 1. 2012-09-06. PMID:20848610. |
these findings support the idea that bdnf actions modify subsequent synaptic plasticity; a homeostatic mechanism thought to be essential for synaptic integration among prolonged temporal domains in the adult mammalian brain. |
2012-09-06 |
2023-08-12 |
human |
Yuji Matsuya, Daisuke Ihara, Mamoru Fukuchi, Daisuke Honma, Kiyoshi Itoh, Akiko Tabuchi, Hideo Nemoto, Masaaki Tsud. Synthesis and biological evaluation of pyrethroid insecticide-derivatives as a chemical inducer for Bdnf mRNA expression in neurons. Bioorganic & medicinal chemistry. vol 20. issue 8. 2012-09-04. PMID:22429507. |
brain-derived neurotrophic factor (bdnf) plays a fundamental role in neuronal synaptic plasticity. |
2012-09-04 |
2023-08-12 |
human |
James P Shaffery, Jorge Lopez, Howard P Roffwar. Brain-derived neurotrophic factor (BDNF) reverses the effects of rapid eye movement sleep deprivation (REMSD) on developmentally regulated, long-term potentiation (LTP) in visual cortex slices. Neuroscience letters. vol 513. issue 1. 2012-08-24. PMID:22361363. |
intracortical infusion of bdnf in remsd adolescent rats appears to restore neurochemical processes necessary for termination of the cp for developmentally regulated synaptic plasticity in visual cortex. |
2012-08-24 |
2023-08-12 |
rat |
Shelley J Allen, Judy J Watson, David Dawbar. The neurotrophins and their role in Alzheimer's disease. Current neuropharmacology. vol 9. issue 4. 2012-08-23. PMID:22654716. |
this review briefly describes the pathology, symptoms and molecular processes associated with alzheimer's disease; it discusses the involvement of the neurotrophins, particularly ngf and bdnf, and their receptors, with changes in bdnf considered particularly in the light of its importance in synaptic plasticity. |
2012-08-23 |
2023-08-12 |
Not clear |
Min Li, Fu-Rong Dai, Xiao-Ping Du, Qi-Dong Yang, Xiuwu Zhang, Yuxiang Che. Infusion of BDNF into the nucleus accumbens of aged rats improves cognition and structural synaptic plasticity through PI3K-ILK-Akt signaling. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22446058. |
infusion of bdnf into the nucleus accumbens of aged rats improves cognition and structural synaptic plasticity through pi3k-ilk-akt signaling. |
2012-08-20 |
2023-08-12 |
rat |
Min Li, Fu-Rong Dai, Xiao-Ping Du, Qi-Dong Yang, Xiuwu Zhang, Yuxiang Che. Infusion of BDNF into the nucleus accumbens of aged rats improves cognition and structural synaptic plasticity through PI3K-ILK-Akt signaling. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22446058. |
importantly, infusion of bdnf restored cognition, synaptic plasticity, and cell signaling. |
2012-08-20 |
2023-08-12 |
rat |
Min Li, Fu-Rong Dai, Xiao-Ping Du, Qi-Dong Yang, Xiuwu Zhang, Yuxiang Che. Infusion of BDNF into the nucleus accumbens of aged rats improves cognition and structural synaptic plasticity through PI3K-ILK-Akt signaling. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22446058. |
our study suggested that the decreased bdnf level and its downstream signaling as well as loss of synaptic plasticity in the nac are associated with cognitive impairments in aged rats. |
2012-08-20 |
2023-08-12 |
rat |
Shinji Yamaguchi, Naoya Aoki, Daisuke Kobayashi, Takaaki Kitajima, Eiji Iikubo, Sachiko Katagiri, Toshiya Matsushima, Koichi J Homm. Activation of brain-derived neurotrophic factor/tropomyosin-related kinase B signaling accompanying filial imprinting in domestic chicks (Gallus gallus domesticus). Neuroreport. vol 22. issue 17. 2012-08-08. PMID:22015740. |
brain-derived neurotrophic factor (bdnf) has been shown to play a critical role in synaptic plasticity, including long-term potentiation, which underlies learning and memory in rodents. |
2012-08-08 |
2023-08-12 |
chicken |
Ira Driscoll, Bronwen Martin, Yang An, Stuart Maudsley, Luigi Ferrucci, Mark P Mattson, Susan M Resnic. Plasma BDNF is associated with age-related white matter atrophy but not with cognitive function in older, non-demented adults. PloS one. vol 7. issue 4. 2012-08-03. PMID:22523577. |
brain derived neurotrophic factor (bdnf) seems to be involved in regulation of synaptic plasticity and neurogenesis. |
2012-08-03 |
2023-08-12 |
Not clear |