| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sylvie Burnouf, Alberto Martire, Maxime Derisbourg, Cyril Laurent, Karim Belarbi, Antoine Leboucher, Francisco J Fernandez-Gomez, Laetitia Troquier, Sabiha Eddarkaoui, Marie-Eve Grosjean, Dominique Demeyer, Anne Muhr-Tailleux, Alain Buisson, Nicolas Sergeant, Malika Hamdane, Sandrine Humez, Patrizia Popoli, Luc Buée, David Blu. NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model. Aging cell. vol 12. issue 1. 2013-09-30. PMID:23082852. |
both brain-derived neurotrophic factor (bdnf) and its tyrosine kinase receptor trkb play a critical role in hippocampus-dependent synaptic plasticity and memory. |
2013-09-30 |
2023-08-12 |
mouse |
| Naoki Adachi, Tadahiro Numakawa, Emi Kumamaru, Chiaki Itami, Shuichi Chiba, Yoshimi Iijima, Misty Richards, Ritsuko Katoh-Semba, Hiroshi Kunug. Phencyclidine-induced decrease of synaptic connectivity via inhibition of BDNF secretion in cultured cortical neurons. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 4. 2013-09-23. PMID:22467667. |
considering that brain-derived neurotrophic factor (bdnf) plays an important role in synaptic plasticity, we examined whether exposure to pcp leads to impaired bdnf function in cultured cortical neurons. |
2013-09-23 |
2023-08-12 |
Not clear |
| Ritabrata Banerjee, Anup K Ghosh, Balaram Ghosh, Somnath Bhattacharyya, Amal C Monda. Decreased mRNA and Protein Expression of BDNF, NGF, and their Receptors in the Hippocampus from Suicide: An Analysis in Human Postmortem Brain. Clinical medicine insights. Pathology. vol 6. 2013-09-13. PMID:24031163. |
given the importance of bdnf and ngf and their cognate receptors in mediating physiological functions, including cell survival and synaptic plasticity, our findings of reduced expression of bdnf, trkb, ngf, and trka on both the protein and mrna levels of postmortem brains of suicide victims suggest that these molecules may play an important role in the pathophysiological aspects of suicidal behavior. |
2013-09-13 |
2023-08-12 |
human |
| Hussam Jourdi, Mohamed Kabba. Acute BDNF treatment upregulates GluR1-SAP97 and GluR2-GRIP1 interactions: implications for sustained AMPA receptor expression. PloS one. vol 8. issue 2. 2013-09-03. PMID:23460828. |
brain-derived neurotrophic factor (bdnf) plays several prominent roles in synaptic plasticity and in learning and memory formation. |
2013-09-03 |
2023-08-12 |
Not clear |
| Madhurima Benekareddy, Amrita R Nair, Brian G Dias, Deepika Suri, Anita E Autry, Lisa M Monteggia, Vidita A Vaidy. Induction of the plasticity-associated immediate early gene Arc by stress and hallucinogens: role of brain-derived neurotrophic factor. The international journal of neuropsychopharmacology. vol 16. issue 2. 2013-08-21. PMID:22404904. |
these findings suggest the possibility that the regulation of arc expression via bdnf provides a molecular substrate for the structural and synaptic plasticity observed following stimuli such as stress and hallucinogens. |
2013-08-21 |
2023-08-12 |
mouse |
| Wallace C Duncan, Simone Sarasso, Fabio Ferrarelli, Jessica Selter, Brady A Riedner, Nadia S Hejazi, Peixiong Yuan, Nancy Brutsche, Husseini K Manji, Giulio Tononi, Carlos A Zarat. Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder. The international journal of neuropsychopharmacology. vol 16. issue 2. 2013-08-21. PMID:22676966. |
this study investigated the acute effects of a single ketamine infusion on depressive symptoms, eeg swa, individual slow wave parameters (surrogate markers of central synaptic plasticity) and plasma bdnf (a peripheral marker of plasticity) in 30 patients with treatment-resistant mdd. |
2013-08-21 |
2023-08-12 |
rat |
| Wallace C Duncan, Simone Sarasso, Fabio Ferrarelli, Jessica Selter, Brady A Riedner, Nadia S Hejazi, Peixiong Yuan, Nancy Brutsche, Husseini K Manji, Giulio Tononi, Carlos A Zarat. Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder. The international journal of neuropsychopharmacology. vol 16. issue 2. 2013-08-21. PMID:22676966. |
intriguingly, this link was present only in patients who responded to ketamine treatment, suggesting that enhanced synaptic plasticity - as reflected by increased swa, individual slow wave parameters and plasma bdnf - is part of the physiological mechanism underlying the rapid antidepressant effects of nmda antagonists. |
2013-08-21 |
2023-08-12 |
rat |
| Sharain Suliman, Sian M J Hemmings, Soraya Seeda. Brain-Derived Neurotrophic Factor (BDNF) protein levels in anxiety disorders: systematic review and meta-regression analysis. Frontiers in integrative neuroscience. vol 7. 2013-08-05. PMID:23908608. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that is involved in the synaptic plasticity and survival of neurons. |
2013-08-05 |
2023-08-12 |
Not clear |
| Chirayu D Pandya, Ammar Kutiyanawalla, Anilkumar Pilla. BDNF-TrkB signaling and neuroprotection in schizophrenia. Asian journal of psychiatry. vol 6. issue 1. 2013-07-29. PMID:23380313. |
neurotrophins such as brain-derived neurotropic factor (bdnf), play critical role in neuronal survival, synaptic plasticity and cognitive functions. |
2013-07-29 |
2023-08-12 |
human |
| Carlos V Melo, Miranda Mele, Michele Curcio, Diogo Comprido, Carla G Silva, Carlos B Duart. BDNF regulates the expression and distribution of vesicular glutamate transporters in cultured hippocampal neurons. PloS one. vol 8. issue 1. 2013-07-19. PMID:23326507. |
bdnf is a pro-survival protein involved in neuronal development and synaptic plasticity. |
2013-07-19 |
2023-08-12 |
rat |
| Bai Lu, Guhan Nagappan, Xiaoming Guan, Pradeep J Nathan, Paul Wre. BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases. Nature reviews. Neuroscience. vol 14. issue 6. 2013-07-16. PMID:23674053. |
understanding the role of brain-derived neurotrophic factor (bdnf) in synaptic plasticity and synaptogenesis, the impact of the bdnf val66met polymorphism in alzheimer's disease-relevant endophenotypes - including episodic memory and hippocampal volume - and the technological progress in measuring synaptic changes in humans all pave the way for a 'synaptic repair' therapy for neurodegenerative diseases that targets pathophysiology rather than pathogenesis. |
2013-07-16 |
2023-08-12 |
Not clear |
| Sachin Moonat, Subhash C Pande. Stress, epigenetics, and alcoholism. Alcohol research : current reviews. vol 34. issue 4. 2013-07-01. PMID:23584115. |
aberrant regulation of bdnf signaling and alterations in synapse activity (i.e., synaptic plasticity) have been associated with the pathophysiology of stress-related disorders and alcoholism. |
2013-07-01 |
2023-08-12 |
Not clear |
| Sachin Moonat, Subhash C Pande. Stress, epigenetics, and alcoholism. Alcohol research : current reviews. vol 34. issue 4. 2013-07-01. PMID:23584115. |
studies regarding the epigenetic control of bdnf signaling and synaptic plasticity provide a promising direction to understand the mechanisms mediating the interaction between stress and alcoholism. |
2013-07-01 |
2023-08-12 |
Not clear |
| Zhe Ying, Cameron Feng, Rahul Agrawal, Yumei Zhuang, Fernando Gomez-Pinill. Dietary omega-3 deficiency from gestation increases spinal cord vulnerability to traumatic brain injury-induced damage. PloS one. vol 7. issue 12. 2013-06-24. PMID:23300842. |
tbi reduced levels of molecular systems important for synaptic plasticity (bdnf, trkb, and creb) and plasma membrane homeostasis (4-hne, ipla2, syntaxin-3) in the lumbar spinal cord. |
2013-06-24 |
2023-08-12 |
Not clear |
| Adriana Fernanda Vizuete, Daniela Fraga de Souza, Maria Cristina Guerra, Cristiane Batassini, Márcio Ferreira Dutra, Caren Bernardi, Ana Paula Costa, Carlos-Alberto Gonçalve. Brain changes in BDNF and S100B induced by ketogenic diets in Wistar rats. Life sciences. vol 92. issue 17-19. 2013-06-20. PMID:23557853. |
we investigated the effects of ketogenic diet (kd) on levels of tumor necrosis factor alpha (tnf-α, a classical pro-inflammatory cytokine), bdnf (brain-derived neurotrophic factor, commonly associated with synaptic plasticity), and s100b, an astrocyte neurotrophic cytokine involved in metabolism regulation. |
2013-06-20 |
2023-08-12 |
rat |
| M S Joseph, N J K Tillakaratne, R D de Leo. Treadmill training stimulates brain-derived neurotrophic factor mRNA expression in motor neurons of the lumbar spinal cord in spinally transected rats. Neuroscience. vol 224. 2013-06-17. PMID:22917619. |
the findings support a mechanism by which postsynaptic release of bdnf from motor neurons contributed to synaptic plasticity. |
2013-06-17 |
2023-08-12 |
rat |
| Julie Seibt, Marcos G Fran. Translation regulation in sleep: Making experience last. Communicative & integrative biology. vol 5. issue 5. 2013-06-07. PMID:23739213. |
we demonstrate that activation of the mammalian target of rapamycin [mtor] pathway, an important regulator of translation initiation,(4) is necessary for sleep-dependent odp consolidation and that sleep promotes translation (but not transcription) of proteins essential for synaptic plasticity (i.e., arc and bdnf). |
2013-06-07 |
2023-08-12 |
cat |
| Yue Wang, Tian-Yi Zhang, Jian Xin, Ting Li, Hui Yu, Na Li, Zhe-Yu Che. Differential involvement of brain-derived neurotrophic factor in reconsolidation and consolidation of conditioned taste aversion memory. PloS one. vol 7. issue 11. 2013-05-30. PMID:23185492. |
brain-derived neurotrophic factor (bdnf) plays a critical role in synaptic plasticity and memory processes. |
2013-05-30 |
2023-08-12 |
Not clear |
| Alessio Travaglia, Diego La Mendola, Antonio Magrì, Vincenzo Giuseppe Nicoletti, Adriana Pietropaolo, Enrico Rizzarell. Copper, BDNF and Its N-terminal domain: inorganic features and biological perspectives. Chemistry (Weinheim an der Bergstrasse, Germany). vol 18. issue 49. 2013-05-23. PMID:23135810. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that influences development, maintenance, survival, and synaptic plasticity of central and peripheral nervous systems. |
2013-05-23 |
2023-08-12 |
human |
| Leonardo A Ortega, Brittany A Tracy, Thomas J Gould, Vinay Parik. Effects of chronic low- and high-dose nicotine on cognitive flexibility in C57BL/6J mice. Behavioural brain research. vol 238. 2013-05-17. PMID:23103711. |
as frontostriatal circuits involving discrete regions of dorsal striatum contribute directly to decision-making processes, and bdnf modulates synaptic plasticity and learning, we also assessed the effects of nicotine on striatal bdnf expression. |
2013-05-17 |
2023-08-12 |
mouse |