Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Marta Zagrebelsky, Martin Kort. Form follows function: BDNF and its involvement in sculpting the function and structure of synapses. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23752094. |
in this review we would like to summarize what is known regarding the cellular mechanism mediating the activity of bdnf during functional and/or structural changes at neurons in order to promote synaptic plasticity. |
2014-08-06 |
2023-08-12 |
Not clear |
Elke Edelmann, Volkmar Lessmann, Tanja Brigadsk. Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23791959. |
pre- and postsynaptic twists in bdnf secretion and action in synaptic plasticity. |
2014-08-06 |
2023-08-12 |
Not clear |
Elke Edelmann, Volkmar Lessmann, Tanja Brigadsk. Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23791959. |
overwhelming evidence collected since the early 1990's strongly supports the notion that bdnf is among the key regulators of synaptic plasticity in many areas of the mammalian central nervous system. |
2014-08-06 |
2023-08-12 |
Not clear |
Elke Edelmann, Volkmar Lessmann, Tanja Brigadsk. Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23791959. |
thus, our review will discuss the data currently available regarding synaptic bdnf secretion in response to physiologically relevant levels of activity, and will discuss how endogenously secreted bdnf affects synaptic plasticity, giving a special focus on spike timing-dependent types of ltp and on mossy fiber ltp. |
2014-08-06 |
2023-08-12 |
Not clear |
Raül Andero, Dennis C Choi, Kerry J Ressle. BDNF-TrkB receptor regulation of distributed adult neural plasticity, memory formation, and psychiatric disorders. Progress in molecular biology and translational science. vol 122. 2014-07-31. PMID:24484701. |
brain-derived neurotrophic factor (bdnf) and its single transmembrane receptor, tropomysin-related kinase b (trkb), are essential for adult synaptic plasticity and the formation of memories. |
2014-07-31 |
2023-08-12 |
Not clear |
Joan C Han, Audrey Thurm, Christine Golden Williams, Lisa A Joseph, Wadih M Zein, Brian P Brooks, John A Butman, Sheila M Brady, Shannon R Fuhr, Melanie D Hicks, Amanda E Huey, Alyson E Hanish, Kristen M Danley, Margarita J Raygada, Owen M Rennert, Keri Martinowich, Stephen J Sharp, Jack W Tsao, Susan E Swed. Association of brain-derived neurotrophic factor (BDNF) haploinsufficiency with lower adaptive behaviour and reduced cognitive functioning in WAGR/11p13 deletion syndrome. Cortex; a journal devoted to the study of the nervous system and behavior. vol 49. issue 10. 2014-07-30. PMID:23517654. |
in animal studies, brain-derived neurotrophic factor (bdnf) is an important regulator of central nervous system development and synaptic plasticity. |
2014-07-30 |
2023-08-12 |
human |
P Michael Iuvone, Jeffrey H Boatright, Gianluca Tosini, Keqiang Y. N-acetylserotonin: circadian activation of the BDNF receptor and neuroprotection in the retina and brain. Advances in experimental medicine and biology. vol 801. 2014-07-24. PMID:24664769. |
trkb is the cognate receptor for brain-derived neurotrophic factor (bdnf), a member of the neurotrophin family involved in neuronal survival, neurogenesis and synaptic plasticity. |
2014-07-24 |
2023-08-12 |
mouse |
b' Max Nordgren, Tobias Karlsson, Maria Svensson, Josefin Koczy, Anna Josephson, Lars Olson, Anders Tingstr\\xc3\\xb6m, Stefan Bren\\xc3\\xa. Orchestrated regulation of Nogo receptors, LOTUS, AMPA receptors and BDNF in an ECT model suggests opening and closure of a window of synaptic plasticity. PloS one. vol 8. issue 11. 2014-07-22. PMID:24244357.' |
orchestrated regulation of nogo receptors, lotus, ampa receptors and bdnf in an ect model suggests opening and closure of a window of synaptic plasticity. |
2014-07-22 |
2023-08-12 |
rat |
K H Alzoubi, O F Khabour, I A Alhaidar, A M Aleisa, K A Alkadh. Diabetes impairs synaptic plasticity in the superior cervical ganglion: possible role for BDNF and oxidative stress. Journal of molecular neuroscience : MN. vol 51. issue 3. 2014-06-23. PMID:23832486. |
diabetes impairs synaptic plasticity in the superior cervical ganglion: possible role for bdnf and oxidative stress. |
2014-06-23 |
2023-08-12 |
rat |
K H Alzoubi, O F Khabour, I A Alhaidar, A M Aleisa, K A Alkadh. Diabetes impairs synaptic plasticity in the superior cervical ganglion: possible role for BDNF and oxidative stress. Journal of molecular neuroscience : MN. vol 51. issue 3. 2014-06-23. PMID:23832486. |
in this study, we examined the effect of streptozocin (stz)-induced diabetes on activity-dependent synaptic plasticity, associated levels of brain-derived neurotrophic factor (bdnf) and antioxidant biomarkers in the rat sympathetic superior cervical ganglion. |
2014-06-23 |
2023-08-12 |
rat |
K H Alzoubi, O F Khabour, I A Alhaidar, A M Aleisa, K A Alkadh. Diabetes impairs synaptic plasticity in the superior cervical ganglion: possible role for BDNF and oxidative stress. Journal of molecular neuroscience : MN. vol 51. issue 3. 2014-06-23. PMID:23832486. |
in conclusion, impaired basal synaptic transmission and synaptic plasticity are associated with reduced bdnf and altered oxidative stress biomarkers in the sympathetic ganglia from stz-induced diabetic animals, suggesting a possible correlation of these factors with the manifestations of stz-induced diabetes in the peripheral nervous system. |
2014-06-23 |
2023-08-12 |
rat |
E Kádár, G Huguet, L Aldavert-Vera, I Morgado-Bernal, P Segura-Torre. Intracranial self stimulation upregulates the expression of synaptic plasticity related genes and Arc protein expression in rat hippocampus. Genes, brain, and behavior. vol 12. issue 8. 2014-06-23. PMID:23898803. |
in particular, expression of creb-dependent synaptic plasticity related genes (c-fos, arc, bdnf, ptgs-2 and crem and icer) was regulated in a time-dependent manner following treatment administration. |
2014-06-23 |
2023-08-12 |
rat |
Teresa Tsai, Alice Klausmeyer, Rebecca Conrad, Christine Gottschling, Markus Leo, Andreas Faissner, Stefan Wies. 7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways. Molecular and cellular neurosciences. vol 56. 2014-06-20. PMID:23500004. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophin family and a ligand for the tropomyosin-receptor kinase b (trkb), mediates neuronal survival, differentiation, and synaptic plasticity. |
2014-06-20 |
2023-08-12 |
mouse |
Julia Leschik, Robert Eckenstaler, Katja Nieweg, Petra Lichtenecker, Tanja Brigadski, Kurt Gottmann, Volkmar Lessmann, Beat Lut. Embryonic stem cells stably expressing BDNF-GFP exhibit a BDNF-release-dependent enhancement of neuronal differentiation. Journal of cell science. vol 126. issue Pt 21. 2014-06-03. PMID:23986480. |
brain-derived neurotrophic factor (bdnf) is known to be a crucial regulator of neuronal survival and synaptic plasticity in the mammalian brain. |
2014-06-03 |
2023-08-12 |
mouse |
Meagan Osborn, Nazneen Rustom, Melanie Clarke, Darcy Litteljohn, Chris Rudyk, Hymie Anisman, Shawn Hayle. Antidepressant-like effects of erythropoietin: a focus on behavioural and hippocampal processes. PloS one. vol 8. issue 9. 2014-05-16. PMID:24019878. |
this has led to an increased focus on treatment strategies that target brain derived neurotrophic factor (bdnf), synaptic plasticity and adult neurogenesis. |
2014-05-16 |
2023-08-12 |
mouse |
Pooja Pallavi, Rajesh Sagar, Manju Mehta, Subhadra Sharma, Arulselvi Subramanium, Farah Shamshi, Utpal Sengupta, Rizwana Qadri, Ravindra M Pandey, Asok K Mukhopadhya. Serum neurotrophic factors in adolescent depression: gender difference and correlation with clinical severity. Journal of affective disorders. vol 150. issue 2. 2014-05-05. PMID:23769609. |
brain derived neurotrophic factor (bdnf), nerve growth factor (ngf), neurotrophin-3 (nt-3) and glial cell line derived neurotrophic factor (gdnf) play critical role in growth, differentiation, maintenance and synaptic plasticity in neuronal systems which is more relevant in adolescence. |
2014-05-05 |
2023-08-12 |
Not clear |
Thomas Andreska, Sarah Aufmkolk, Markus Sauer, Robert Blu. High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons. Frontiers in cellular neuroscience. vol 8. 2014-04-30. PMID:24782711. |
our data proof that hippocampal neurons are able to enrich and store high amounts of bdnf in small granules within the mature glutamatergic presynapse, at a principle site of synaptic plasticity. |
2014-04-30 |
2023-08-13 |
Not clear |
Akira Yoshii, Martha Constantine-Pato. Postsynaptic localization of PSD-95 is regulated by all three pathways downstream of TrkB signaling. Frontiers in synaptic neuroscience. vol 6. 2014-04-18. PMID:24744726. |
brain-derived neurotrophic factor (bdnf) and its receptor trkb regulate synaptic plasticity. |
2014-04-18 |
2023-08-13 |
Not clear |
Michal Taler, Oded Miron, Irit Gil-Ad, Abraham Weizma. Neuroprotective and procognitive effects of sertraline: in vitro and in vivo studies. Neuroscience letters. vol 550. 2014-04-11. PMID:23827216. |
selective serotonin reuptake inhibitors (ssris) stimulate synaptic plasticity and neurogenesis, most likely via the map-kinase signal transduction pathway (by phosphorilation of erk) and by stimulating neurotrophic factors such as brain derived neurotrophic factor (bdnf) and the neuroprotective protein (bcl-2). |
2014-04-11 |
2023-08-12 |
mouse |
M Al-Qudah, C D Anderson, S Mahavadi, Z L Bradley, H I Akbarali, K S Murthy, J R Gride. Brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase C. American journal of physiology. Gastrointestinal and liver physiology. vol 306. issue 4. 2014-04-10. PMID:24356881. |
brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase c. brain-derived neurotrophic factor (bdnf) belongs to the neurotrophin family of proteins best known for its role in neuronal survival, differentiation, migration, and synaptic plasticity in central and peripheral neurons. |
2014-04-10 |
2023-08-12 |
rabbit |