| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Kádár, G Huguet, L Aldavert-Vera, I Morgado-Bernal, P Segura-Torre. Intracranial self stimulation upregulates the expression of synaptic plasticity related genes and Arc protein expression in rat hippocampus. Genes, brain, and behavior. vol 12. issue 8. 2014-06-23. PMID:23898803. |
in particular, expression of creb-dependent synaptic plasticity related genes (c-fos, arc, bdnf, ptgs-2 and crem and icer) was regulated in a time-dependent manner following treatment administration. |
2014-06-23 |
2023-08-12 |
rat |
| Teresa Tsai, Alice Klausmeyer, Rebecca Conrad, Christine Gottschling, Markus Leo, Andreas Faissner, Stefan Wies. 7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways. Molecular and cellular neurosciences. vol 56. 2014-06-20. PMID:23500004. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophin family and a ligand for the tropomyosin-receptor kinase b (trkb), mediates neuronal survival, differentiation, and synaptic plasticity. |
2014-06-20 |
2023-08-12 |
mouse |
| Julia Leschik, Robert Eckenstaler, Katja Nieweg, Petra Lichtenecker, Tanja Brigadski, Kurt Gottmann, Volkmar Lessmann, Beat Lut. Embryonic stem cells stably expressing BDNF-GFP exhibit a BDNF-release-dependent enhancement of neuronal differentiation. Journal of cell science. vol 126. issue Pt 21. 2014-06-03. PMID:23986480. |
brain-derived neurotrophic factor (bdnf) is known to be a crucial regulator of neuronal survival and synaptic plasticity in the mammalian brain. |
2014-06-03 |
2023-08-12 |
mouse |
| Meagan Osborn, Nazneen Rustom, Melanie Clarke, Darcy Litteljohn, Chris Rudyk, Hymie Anisman, Shawn Hayle. Antidepressant-like effects of erythropoietin: a focus on behavioural and hippocampal processes. PloS one. vol 8. issue 9. 2014-05-16. PMID:24019878. |
this has led to an increased focus on treatment strategies that target brain derived neurotrophic factor (bdnf), synaptic plasticity and adult neurogenesis. |
2014-05-16 |
2023-08-12 |
mouse |
| Pooja Pallavi, Rajesh Sagar, Manju Mehta, Subhadra Sharma, Arulselvi Subramanium, Farah Shamshi, Utpal Sengupta, Rizwana Qadri, Ravindra M Pandey, Asok K Mukhopadhya. Serum neurotrophic factors in adolescent depression: gender difference and correlation with clinical severity. Journal of affective disorders. vol 150. issue 2. 2014-05-05. PMID:23769609. |
brain derived neurotrophic factor (bdnf), nerve growth factor (ngf), neurotrophin-3 (nt-3) and glial cell line derived neurotrophic factor (gdnf) play critical role in growth, differentiation, maintenance and synaptic plasticity in neuronal systems which is more relevant in adolescence. |
2014-05-05 |
2023-08-12 |
Not clear |
| Thomas Andreska, Sarah Aufmkolk, Markus Sauer, Robert Blu. High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons. Frontiers in cellular neuroscience. vol 8. 2014-04-30. PMID:24782711. |
our data proof that hippocampal neurons are able to enrich and store high amounts of bdnf in small granules within the mature glutamatergic presynapse, at a principle site of synaptic plasticity. |
2014-04-30 |
2023-08-13 |
Not clear |
| Akira Yoshii, Martha Constantine-Pato. Postsynaptic localization of PSD-95 is regulated by all three pathways downstream of TrkB signaling. Frontiers in synaptic neuroscience. vol 6. 2014-04-18. PMID:24744726. |
brain-derived neurotrophic factor (bdnf) and its receptor trkb regulate synaptic plasticity. |
2014-04-18 |
2023-08-13 |
Not clear |
| Michal Taler, Oded Miron, Irit Gil-Ad, Abraham Weizma. Neuroprotective and procognitive effects of sertraline: in vitro and in vivo studies. Neuroscience letters. vol 550. 2014-04-11. PMID:23827216. |
selective serotonin reuptake inhibitors (ssris) stimulate synaptic plasticity and neurogenesis, most likely via the map-kinase signal transduction pathway (by phosphorilation of erk) and by stimulating neurotrophic factors such as brain derived neurotrophic factor (bdnf) and the neuroprotective protein (bcl-2). |
2014-04-11 |
2023-08-12 |
mouse |
| M Al-Qudah, C D Anderson, S Mahavadi, Z L Bradley, H I Akbarali, K S Murthy, J R Gride. Brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase C. American journal of physiology. Gastrointestinal and liver physiology. vol 306. issue 4. 2014-04-10. PMID:24356881. |
brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase c. brain-derived neurotrophic factor (bdnf) belongs to the neurotrophin family of proteins best known for its role in neuronal survival, differentiation, migration, and synaptic plasticity in central and peripheral neurons. |
2014-04-10 |
2023-08-12 |
rabbit |
| Ethika Tyagi, Rahul Agrawal, Zhe Ying, Fernando Gomez-Pinill. TBI and sex: crucial role of progesterone protecting the brain in an omega-3 deficient condition. Experimental neurology. vol 253. 2014-04-07. PMID:24361060. |
a similar pattern was observed for markers of membrane homeostasis such as 4-hydroxynonenal (hne) and secreted phospholipases a2 (spla2), synaptic plasticity such as brain derived neurotrophic factor (bdnf), syntaxin (stx)-3 and growth associated protein (gap)-43, and for growth inhibitory molecules such as myelin-associated glycoprotein (mag) and nogo-a. |
2014-04-07 |
2023-08-12 |
rat |
| Christopher Heise, Fabrizio Gardoni, Lorenza Culotta, Monica di Luca, Chiara Verpelli, Carlo Sal. Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons. Frontiers in cellular neuroscience. vol 8. 2014-03-25. PMID:24574971. |
well-established targets of eef2k in dendrites include brain-derived neurotrophic factor (bdnf), activity-regulated cytoskeletal-associated protein (arc), the alpha subunit of calcium/cam-dependent protein kinase ii (αcamkii), and microtubule-associated protein 1b (map1b), all of which have well-known functions in different forms of synaptic plasticity. |
2014-03-25 |
2023-08-12 |
Not clear |
| Galit Weinstein, Alexa S Beiser, Seung Hoan Choi, Sarah R Preis, Tai C Chen, Demetrios Vorgas, Rhoda Au, Aleksandra Pikula, Philip A Wolf, Anita L DeStefano, Ramachandran S Vasan, Sudha Seshadr. Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study. JAMA neurology. vol 71. issue 1. 2014-03-17. PMID:24276217. |
in animal studies, brain-derived neurotrophic factor (bdnf) has been shown to impact neuronal survival and function and improve synaptic plasticity and long-term memory. |
2014-03-17 |
2023-08-12 |
human |
| Retraction: Zeng et al., Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 50. 2014-03-07. PMID:24336737. |
retraction: zeng et al., epigenetic enhancement of bdnf signaling rescues synaptic plasticity in aging. |
2014-03-07 |
2023-08-12 |
Not clear |
| Christopher N Parkhurst, Guang Yang, Ipe Ninan, Jeffrey N Savas, John R Yates, Juan J Lafaille, Barbara L Hempstead, Dan R Littman, Wen-Biao Ga. Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor. Cell. vol 155. issue 7. 2014-02-26. PMID:24360280. |
microglial bdnf increases neuronal tropomyosin-related kinase receptor b phosphorylation, a key mediator of synaptic plasticity. |
2014-02-26 |
2023-08-12 |
mouse |
| Ditte Olsen, Mathias Kaas, Ole Schwartz, Anders Nykjaer, Simon Gleru. Loss of BDNF or its receptors in three mouse models has unpredictable consequences for anxiety and fear acquisition. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 9. 2014-02-17. PMID:23959707. |
mature bdnf signals through trkb, while its precursor probdnf employs p75(ntr), resulting in activation of signaling cascades with opposite effects on neuronal survival, growth cone decisions, and synaptic plasticity. |
2014-02-17 |
2023-08-12 |
mouse |
| Tempei Ikegame, Miki Bundo, Yui Murata, Kiyoto Kasai, Tadafumi Kato, Kazuya Iwamot. DNA methylation of the BDNF gene and its relevance to psychiatric disorders. Journal of human genetics. vol 58. issue 7. 2014-02-12. PMID:23739121. |
brain-derived neurotrophic factor (bdnf) is a neurotrophic factor, which is important for neuronal survival, development and synaptic plasticity. |
2014-02-12 |
2023-08-12 |
Not clear |
| Jean-Charles Lamy, Maxwell Boaky. BDNF Val66Met polymorphism alters spinal DC stimulation-induced plasticity in humans. Journal of neurophysiology. vol 110. issue 1. 2014-01-24. PMID:23576701. |
the brain-derived neurotrophic factor gene (bdnf) is one of many genes thought to influence neuronal survival, synaptic plasticity, and neurogenesis. |
2014-01-24 |
2023-08-12 |
human |
| Sandra Schildt, Thomas Endres, Volkmar Lessmann, Elke Edelman. Acute and chronic interference with BDNF/TrkB-signaling impair LTP selectively at mossy fiber synapses in the CA3 region of mouse hippocampus. Neuropharmacology. vol 71. 2014-01-10. PMID:23587649. |
brain-derived neurotrophic factor (bdnf) signaling via trkb crucially regulates synaptic plasticity in the brain. |
2014-01-10 |
2023-08-12 |
mouse |
| Sandra Schildt, Thomas Endres, Volkmar Lessmann, Elke Edelman. Acute and chronic interference with BDNF/TrkB-signaling impair LTP selectively at mossy fiber synapses in the CA3 region of mouse hippocampus. Neuropharmacology. vol 71. 2014-01-10. PMID:23587649. |
although bdnf is abundant at hippocampal mossy fiber (mf) synapses, which critically contribute to hippocampus dependent memory, its role in mf synaptic plasticity (long-term potentiation, ltp) remained largely unclear. |
2014-01-10 |
2023-08-12 |
mouse |
| Brigitte Schulz-Klaus, Volkmar Lessmann, Thomas Endre. BDNF-dependent consolidation of fear memories in the perirhinal cortex. Frontiers in behavioral neuroscience. vol 7. 2014-01-01. PMID:24381548. |
since the neurotrophin brain-derived neurotrophic factor (bdnf) is an important mediator of synaptic plasticity and also crucially involved in memory consolidation of several learning paradigms, we analyzed now whether fear conditioning influences the expression of bdnf protein in the prh. |
2014-01-01 |
2023-08-12 |
Not clear |