Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Toshiyuki Mizui, Yasuyuki Ishikawa, Haruko Kumanogoh, Maria Lume, Tomoya Matsumoto, Tomoko Hara, Shigeto Yamawaki, Masami Takahashi, Sadao Shiosaka, Chiaki Itami, Koichi Uegaki, Mart Saarma, Masami Kojim. BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 23. 2015-09-25. PMID:26015580. |
thus, the bdnf pro-peptide is involved in synaptic plasticity that regulates a mechanism responsible for promoting ltd. |
2015-09-25 |
2023-08-13 |
human |
Ulrika Beitnere, Zane Dzirkale, Sergejs Isajevs, Juris Rumaks, Simons Svirskis, Vija Klus. Carnitine congener mildronate protects against stress- and haloperidol-induced impairment in memory and brain protein expression in rats. European journal of pharmacology. vol 745. 2015-08-24. PMID:25446926. |
the present study investigates the efficacy of mildronate, a carnitine congener, to protect stress and haloperidol-induced impairment of memory in rats and the expression of brain protein biomarkers involved in synaptic plasticity, such as brain-derived neurotrophic factor (bdnf), acetylcholine esterase and glutamate decarboxylase 67 (gad67). |
2015-08-24 |
2023-08-13 |
rat |
Jinwook Kim, Miyoung Yang, Juhwan Kim, Lina Song, Sueun Lee, Yeonghoon Son, Sohi Kang, Chun-Sik Bae, Jong-Choon Kim, Sung-Ho Kim, Taekyun Shin, Hongbing Wang, Changjong Moo. Developmental and degenerative modulation of brain-derived neurotrophic factor transcript variants in the mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 38. 2015-08-21. PMID:25124374. |
brain-derived neurotrophic factor (bdnf) is regarded as an important factor for neurogenesis, synaptic plasticity, and neuronal network organization in brain circuits. |
2015-08-21 |
2023-08-13 |
mouse |
Jinwook Kim, Miyoung Yang, Juhwan Kim, Lina Song, Sueun Lee, Yeonghoon Son, Sohi Kang, Chun-Sik Bae, Jong-Choon Kim, Sung-Ho Kim, Taekyun Shin, Hongbing Wang, Changjong Moo. Developmental and degenerative modulation of brain-derived neurotrophic factor transcript variants in the mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 38. 2015-08-21. PMID:25124374. |
these observations suggest that the differential regulation of bdnf exon transcripts may be associated with neuronal and synaptic maturation during postnatal development, and neuronal survival and synaptic plasticity in chemically induced neurodegeneration. |
2015-08-21 |
2023-08-13 |
mouse |
Xuan Li, Marina E Wol. Multiple faces of BDNF in cocaine addiction. Behavioural brain research. vol 279. 2015-08-20. PMID:25449839. |
last, we will review the role of bdnf in synaptic plasticity, particularly as it relates to plasticity of ampa receptor transmission after cocaine exposure. |
2015-08-20 |
2023-08-13 |
Not clear |
Tanja Novkovic, Thomas Mittmann, Denise Manahan-Vaugha. BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment. Hippocampus. vol 25. issue 1. 2015-08-11. PMID:25112659. |
bdnf contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment. |
2015-08-11 |
2023-08-13 |
mouse |
Tanja Novkovic, Thomas Mittmann, Denise Manahan-Vaugha. BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment. Hippocampus. vol 25. issue 1. 2015-08-11. PMID:25112659. |
as brain-derived neurotrophic factor (bdnf) supports hippocampal long-term potentiation (ltp), we explored whether it participates in the facilitation of synaptic plasticity and hippocampus-dependent learning that occurs following ee. |
2015-08-11 |
2023-08-13 |
mouse |
Tanja Novkovic, Thomas Mittmann, Denise Manahan-Vaugha. BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment. Hippocampus. vol 25. issue 1. 2015-08-11. PMID:25112659. |
these data support that bdnf plays an intrinsic role in improvements of synaptic plasticity and cognition that occur in ee. |
2015-08-11 |
2023-08-13 |
mouse |
Luis M Rodríguez-Serrano, Betsabee Ramírez-León, Luis F Rodríguez-Durán, Martha L Escoba. Acute infusion of brain-derived neurotrophic factor in the insular cortex promotes conditioned taste aversion extinction. Neurobiology of learning and memory. vol 116. 2015-08-07. PMID:25451308. |
brain-derived neurotrophic factor (bdnf) has emerged as one of the most potent molecular mediators not only for synaptic plasticity, but also for the behavioral organism-environment interactions. |
2015-08-07 |
2023-08-13 |
rat |
Jun Ma, Zhanchi Zhang, Lin Kang, Dandan Geng, Yanyong Wang, Mingwei Wang, Huixian Cu. Repetitive transcranial magnetic stimulation (rTMS) influences spatial cognition and modulates hippocampal structural synaptic plasticity in aging mice. Experimental gerontology. vol 58. 2015-08-06. PMID:25172625. |
in conclusion, we infer that aging-induced cognitive deficits are closely associated with hippocampal structural synaptic plasticity, and low-frequency magnetic stimulation plays an important role in regulating cognitive behavior via changing structural synaptic plasticity, and bdnf signaling might participate in this event. |
2015-08-06 |
2023-08-13 |
mouse |
Debabrata Panja, Justin W Kenney, Laura D'Andrea, Francesca Zalfa, Anni Vedeler, Karin Wibrand, Rikiro Fukunaga, Claudia Bagni, Christopher G Proud, Clive R Bramha. Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK. Cell reports. vol 9. issue 4. 2015-07-21. PMID:25453757. |
bdnf signaling contributes to protein-synthesis-dependent synaptic plasticity, but the dynamics of trkb signaling and mechanisms of translation have not been defined. |
2015-07-21 |
2023-08-13 |
Not clear |
Tina B Lonsdorf, Armita Golkar, Kara M Lindström, Jan Haaker, Arne Öhman, Martin Schalling, Martin Ingva. BDNFval66met affects neural activation pattern during fear conditioning and 24 h delayed fear recall. Social cognitive and affective neuroscience. vol 10. issue 5. 2015-07-09. PMID:25103087. |
brain-derived neurotrophic factor (bdnf), the most abundant neutrophin in the mammalian central nervous system, is critically involved in synaptic plasticity. |
2015-07-09 |
2023-08-13 |
human |
Graciano Leal, Pedro M Afonso, Carlos B Duart. Neuronal activity induces synaptic delivery of hnRNP A2/B1 by a BDNF-dependent mechanism in cultured hippocampal neurons. PloS one. vol 9. issue 10. 2015-06-10. PMID:25286195. |
dendritic protein synthesis plays a critical role in several forms of synaptic plasticity, including bdnf (brain-derived neurotrophic factor)-mediated long-term synaptic potentiation (ltp). |
2015-06-10 |
2023-08-13 |
Not clear |
Graciano Leal, Pedro M Afonso, Carlos B Duart. Neuronal activity induces synaptic delivery of hnRNP A2/B1 by a BDNF-dependent mechanism in cultured hippocampal neurons. PloS one. vol 9. issue 10. 2015-06-10. PMID:25286195. |
these results show that the distribution of hnrnp a2/b1 is regulated by bdnf and by neuronal activity, an effect that may have a role in bdnf-induced synaptic plasticity events. |
2015-06-10 |
2023-08-13 |
Not clear |
Peng Zhong, Yong Liu, Ying Hu, Tong Wang, Yong-ping Zhao, Qing-song Li. BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 10. 2015-05-06. PMID:25762688. |
bdnf interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. |
2015-05-06 |
2023-08-13 |
mouse |
Peng Zhong, Yong Liu, Ying Hu, Tong Wang, Yong-ping Zhao, Qing-song Li. BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 10. 2015-05-06. PMID:25762688. |
together, these results suggest that bdnf in dopamine neurons regulates ecb responses, cocaine-induced synaptic plasticity, and associative learning. |
2015-05-06 |
2023-08-13 |
mouse |
Zeeba D Kabir, Bruce Kennedy, Aaron Katzman, Garet P Lahvis, Barry E Kosofsk. Effects of prenatal cocaine exposure on social development in mice. Developmental neuroscience. vol 36. issue 3-4. 2015-04-17. PMID:24852757. |
molecules that mediate synaptic plasticity and learning in the medial prefrontal cortex (mpfc), specifically brain-derived neurotrophic factor (bdnf) and its downstream signaling molecule, early growth response protein 1 (egr1), have been shown to affect the regulation of social interactions (si). |
2015-04-17 |
2023-08-13 |
mouse |
Won Hyuk Chang, Oh Young Bang, Yong-Il Shin, Ahee Lee, Alvaro Pascual-Leone, Yun-Hee Ki. BDNF polymorphism and differential rTMS effects on motor recovery of stroke patients. Brain stimulation. vol 7. issue 4. 2015-04-13. PMID:24767962. |
the brain-derived neurotrophic factor (bdnf) gene often shows a single nucleotide polymorphism that is thought to influence synaptic plasticity. |
2015-04-13 |
2023-08-13 |
Not clear |
Orawan Monthakantirat, Wichitsak Sukano, Kaoru Umehara, Hiroshi Noguchi, Yaowared Chulikhit, Kinzo Matsumot. Effect of miroestrol on ovariectomy-induced cognitive impairment and lipid peroxidation in mouse brain. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 21. issue 11. 2015-03-30. PMID:25172786. |
we examined the effects of mr on cognitive function, oxidative brain damage, and the expression of genes encoding brain-derived neurotrophic factor (bdnf) and cyclic amp-responsive element-binding protein (creb), factors implicated in neurogenesis and synaptic plasticity, in ovariectomized (ovx) mice. |
2015-03-30 |
2023-08-13 |
mouse |
Filippo Vairo, Fernanda Sperb-Ludwig, Matheus Wilke, Kristiane Michellin-Tirelli, Cristina Netto, Eurico Camargo Neto, Ida Vanessa Doederlein Schwart. Brain-derived neurotrophic factor expression increases after enzyme replacement therapy in Gaucher disease. Journal of neuroimmunology. vol 278. 2015-03-23. PMID:25468270. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that is important for the normal development of the peripheral and central nervous system, and it plays a key role in neuronal survival and synaptic plasticity in the adult brain. |
2015-03-23 |
2023-08-13 |
Not clear |