| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tina B Lonsdorf, Armita Golkar, Kara M Lindström, Jan Haaker, Arne Öhman, Martin Schalling, Martin Ingva. BDNFval66met affects neural activation pattern during fear conditioning and 24 h delayed fear recall. Social cognitive and affective neuroscience. vol 10. issue 5. 2015-07-09. PMID:25103087. |
brain-derived neurotrophic factor (bdnf), the most abundant neutrophin in the mammalian central nervous system, is critically involved in synaptic plasticity. |
2015-07-09 |
2023-08-13 |
human |
| Graciano Leal, Pedro M Afonso, Carlos B Duart. Neuronal activity induces synaptic delivery of hnRNP A2/B1 by a BDNF-dependent mechanism in cultured hippocampal neurons. PloS one. vol 9. issue 10. 2015-06-10. PMID:25286195. |
dendritic protein synthesis plays a critical role in several forms of synaptic plasticity, including bdnf (brain-derived neurotrophic factor)-mediated long-term synaptic potentiation (ltp). |
2015-06-10 |
2023-08-13 |
Not clear |
| Graciano Leal, Pedro M Afonso, Carlos B Duart. Neuronal activity induces synaptic delivery of hnRNP A2/B1 by a BDNF-dependent mechanism in cultured hippocampal neurons. PloS one. vol 9. issue 10. 2015-06-10. PMID:25286195. |
these results show that the distribution of hnrnp a2/b1 is regulated by bdnf and by neuronal activity, an effect that may have a role in bdnf-induced synaptic plasticity events. |
2015-06-10 |
2023-08-13 |
Not clear |
| Peng Zhong, Yong Liu, Ying Hu, Tong Wang, Yong-ping Zhao, Qing-song Li. BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 10. 2015-05-06. PMID:25762688. |
bdnf interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. |
2015-05-06 |
2023-08-13 |
mouse |
| Peng Zhong, Yong Liu, Ying Hu, Tong Wang, Yong-ping Zhao, Qing-song Li. BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 10. 2015-05-06. PMID:25762688. |
together, these results suggest that bdnf in dopamine neurons regulates ecb responses, cocaine-induced synaptic plasticity, and associative learning. |
2015-05-06 |
2023-08-13 |
mouse |
| Zeeba D Kabir, Bruce Kennedy, Aaron Katzman, Garet P Lahvis, Barry E Kosofsk. Effects of prenatal cocaine exposure on social development in mice. Developmental neuroscience. vol 36. issue 3-4. 2015-04-17. PMID:24852757. |
molecules that mediate synaptic plasticity and learning in the medial prefrontal cortex (mpfc), specifically brain-derived neurotrophic factor (bdnf) and its downstream signaling molecule, early growth response protein 1 (egr1), have been shown to affect the regulation of social interactions (si). |
2015-04-17 |
2023-08-13 |
mouse |
| Won Hyuk Chang, Oh Young Bang, Yong-Il Shin, Ahee Lee, Alvaro Pascual-Leone, Yun-Hee Ki. BDNF polymorphism and differential rTMS effects on motor recovery of stroke patients. Brain stimulation. vol 7. issue 4. 2015-04-13. PMID:24767962. |
the brain-derived neurotrophic factor (bdnf) gene often shows a single nucleotide polymorphism that is thought to influence synaptic plasticity. |
2015-04-13 |
2023-08-13 |
Not clear |
| Orawan Monthakantirat, Wichitsak Sukano, Kaoru Umehara, Hiroshi Noguchi, Yaowared Chulikhit, Kinzo Matsumot. Effect of miroestrol on ovariectomy-induced cognitive impairment and lipid peroxidation in mouse brain. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 21. issue 11. 2015-03-30. PMID:25172786. |
we examined the effects of mr on cognitive function, oxidative brain damage, and the expression of genes encoding brain-derived neurotrophic factor (bdnf) and cyclic amp-responsive element-binding protein (creb), factors implicated in neurogenesis and synaptic plasticity, in ovariectomized (ovx) mice. |
2015-03-30 |
2023-08-13 |
mouse |
| Filippo Vairo, Fernanda Sperb-Ludwig, Matheus Wilke, Kristiane Michellin-Tirelli, Cristina Netto, Eurico Camargo Neto, Ida Vanessa Doederlein Schwart. Brain-derived neurotrophic factor expression increases after enzyme replacement therapy in Gaucher disease. Journal of neuroimmunology. vol 278. 2015-03-23. PMID:25468270. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that is important for the normal development of the peripheral and central nervous system, and it plays a key role in neuronal survival and synaptic plasticity in the adult brain. |
2015-03-23 |
2023-08-13 |
Not clear |
| Paolo Ghisletta, Lars Bäckman, Lars Bertram, Andreas Markus Brandmaier, Denis Gerstorf, Tian Liu, Ulman Lindenberge. The Val/Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene predicts decline in perceptual speed in older adults. Psychology and aging. vol 29. issue 2. 2015-03-18. PMID:24660789. |
the brain-derived neurotrophic factor (bdnf) promotes activity-dependent synaptic plasticity, and contributes to learning and memory. |
2015-03-18 |
2023-08-12 |
human |
| Jake T Neumann, John W Thompson, Ami P Raval, Charles H Cohan, Kevin B Koronowski, Miguel A Perez-Pinzo. Increased BDNF protein expression after ischemic or PKC epsilon preconditioning promotes electrophysiologic changes that lead to neuroprotection. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 35. issue 1. 2015-03-17. PMID:25370861. |
brain-derived neurotrophic factor (bdnf) is a pro-survival signaling molecule that modulates synaptic plasticity and neurogenesis. |
2015-03-17 |
2023-08-13 |
Not clear |
| Giuseppe Giannotti, Lucia Caffino, Francesca Calabrese, Giorgio Racagni, Marco A Riva, Fabio Fumagall. Prolonged abstinence from developmental cocaine exposure dysregulates BDNF and its signaling network in the medial prefrontal cortex of adult rats. The international journal of neuropsychopharmacology. vol 17. issue 4. 2015-02-12. PMID:24345425. |
these findings demonstrate that developmental exposure to cocaine dynamically dysregulates bdnf and its signaling network in the mpfc of adult rats, providing novel mechanisms that may contribute to cocaine-induced changes in synaptic plasticity. |
2015-02-12 |
2023-08-12 |
rat |
| Martin J Lan, R Todd Ogden, Yung-Yu Huang, Maria A Oquendo, Gregory M Sullivan, Jeffrey Miller, Matthew Milak, J John Mann, Ramin V Parse. Genetic variation in brain-derived neurotrophic factor val66met allele is associated with altered serotonin-1A receptor binding in human brain. NeuroImage. vol 94. 2015-02-06. PMID:24607934. |
brain derived neurotrophic factor (bdnf) regulates brain synaptic plasticity. |
2015-02-06 |
2023-08-12 |
human |
| David A Martin, Danuta Marona-Lewicka, David E Nichols, Charles D Nichol. Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia. Neuropharmacology. vol 83. 2015-01-29. PMID:24704148. |
functional clustering analysis indicates differentially expressed genes are enriched in pathways involving neurotransmission (drd2, gabrb1), synaptic plasticity (nr2a, krox20), energy metabolism (atp5d, ndufa1) and neuropeptide signaling (npy, bdnf), among others. |
2015-01-29 |
2023-08-13 |
rat |
| Yuan-Jian Yang, Yan-Kun Li, Wei Wang, Jian-Guo Wan, Bin Yu, Mei-Zhen Wang, Bin H. Small-molecule TrkB agonist 7,8-dihydroxyflavone reverses cognitive and synaptic plasticity deficits in a rat model of schizophrenia. Pharmacology, biochemistry, and behavior. vol 122. 2015-01-26. PMID:24662915. |
we found that mk-801-treated rats showed significant deficits in working learning ability and hippocampal synaptic plasticity, as well as reduction of bdnf, trkb, and phosphorylated trkb in the hippocampus. |
2015-01-26 |
2023-08-12 |
rat |
| Yixuan Song, Koichi Miyaki, Tomoko Suzuki, Yasuharu Sasaki, Akizumi Tsutsumi, Norito Kawakami, Akihito Shimazu, Masaya Takahashi, Akiomi Inoue, Chiemi Kan, Sumiko Kurioka, Takuro Shimb. Altered DNA methylation status of human brain derived neurotrophis factor gene could be useful as biomarker of depression. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 165B. issue 4. 2015-01-21. PMID:24801253. |
brain-derived neurotrophic factor (bdnf) is involved in the survival, development, and synaptic plasticity of neurons. |
2015-01-21 |
2023-08-13 |
human |
| Aron K Barbey, Roberto Colom, Erick Paul, Chad Forbes, Frank Krueger, David Goldman, Jordan Grafma. Preservation of general intelligence following traumatic brain injury: contributions of the Met66 brain-derived neurotrophic factor. PloS one. vol 9. issue 2. 2015-01-09. PMID:24586380. |
brain-derived neurotrophic factor (bdnf) promotes survival and synaptic plasticity in the human brain. |
2015-01-09 |
2023-08-12 |
human |
| Jianmin Yang, Lauren C Harte-Hargrove, Chia-Jen Siao, Tina Marinic, Roshelle Clarke, Qian Ma, Deqiang Jing, John J Lafrancois, Kevin G Bath, Willie Mark, Douglas Ballon, Francis S Lee, Helen E Scharfman, Barbara L Hempstea. proBDNF negatively regulates neuronal remodeling, synaptic transmission, and synaptic plasticity in hippocampus. Cell reports. vol 7. issue 3. 2015-01-05. PMID:24746813. |
mature brain-derived neurotrophic factor (bdnf) modulates neuronal morphology and synaptic plasticity, including long-term potentiation (ltp) via trkb activation. |
2015-01-05 |
2023-08-13 |
mouse |
| Anand Gururajan, Rachel Hill, Maarten van den Buus. Long-term differential effects of chronic young-adult corticosterone exposure on anxiety and depression-like behaviour in BDNF heterozygous rats depend on the experimental paradigm used. Neuroscience letters. vol 576. 2015-01-05. PMID:24907687. |
brain-derived neurotrophic factor (bdnf) has key roles in neurodevelopment and synaptic plasticity and is implicated in affective disorders such as anxiety and depression. |
2015-01-05 |
2023-08-13 |
rat |
| Natalie Kaplan, Aya Vituri, Amos D Korczyn, Oren S Cohen, Rivka Inzelberg, Gilad Yahalom, Evgenia Kozlova, Roni Milgrom, Yael Laitman, Eitan Friedman, Saharon Rosset, Sharon Hassin-Bae. Sequence variants in SLC6A3, DRD2, and BDNF genes and time to levodopa-induced dyskinesias in Parkinson's disease. Journal of molecular neuroscience : MN. vol 53. issue 2. 2015-01-02. PMID:24633632. |
in order to identify genetic factors associated with lid, 352 (213 males) levodopa-treated israeli pd patients were genotyped for 34 polymorphisms within three candidate genes affecting dopaminergic activity and synaptic plasticity: dopamine transporter gene (dat1 or slc6a3) [14 single nucleotide polymorphisms (snps) and 40-bp variable number tandem repeat (vntr)], drd2 [11 snps and dinucleotide ca short tandem repeat (str)], and bdnf (7 snps). |
2015-01-02 |
2023-08-12 |
human |