| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anu Aonurm-Helm, Kaili Anier, Tamara Zharkovsky, Eero Castrén, Tomi Rantamäki, Vladimir Stepanov, Jaak Järv, Alexander Zharkovsk. NCAM-deficient mice show prominent abnormalities in serotonergic and BDNF systems in brain - Restoration by chronic amitriptyline. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 12. 2016-10-05. PMID:26499173. |
mood disorders are associated with alterations in serotonergic system, deficient bdnf (brain-derived neurotrophic factor) signaling and abnormal synaptic plasticity. |
2016-10-05 |
2023-08-13 |
mouse |
| b' Vesna Pe\\xc5\\xa1i\\xc4\\x87, Desanka Milanovi\\xc4\\x87, Jelena Popi\\xc4\\x87, Kosara Smiljani\\xc4\\x87, Vesna Te\\xc5\\xa1i\\xc4\\x87, Selma Kanazir, Vesna Jevtovi\\xc4\\x87-Todorovi\\xc4\\x87, Sabera Ru\\xc5\\xbediji\\xc4\\x8. Neonatal propofol anesthesia modifies activity-dependent processes and induces transient hyperlocomotor response to d-amphetamine during adolescence in rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 47. issue Pt B. 2016-09-16. PMID:26492981.' |
this study examined the influence of propofol anesthesia on the expression of activity-regulated molecules (bdnf and c-fos) and synaptic plasticity markers (synaptophysin, gap-43, drebrin) in the frontal cortex and thalamus of 7-day-old (p7) rats. |
2016-09-16 |
2023-08-13 |
rat |
| Shingo Nakajima, Tadahiro Numakawa, Naoki Adachi, Yoshiko Ooshima, Haruki Odaka, Aya Yoshimura, Hiroshi Kunug. Self-amplified BDNF transcription is a regulatory system for synaptic maturation in cultured cortical neurons. Neurochemistry international. vol 91. 2016-09-15. PMID:26596846. |
neuronal cell survival and synaptic plasticity are controlled through expression of various neurotrophic factors including brain-derived neurotrophic factor (bdnf). |
2016-09-15 |
2023-08-13 |
Not clear |
| Felix Badinter, Tamar Amit, Orit Bar-Am, Moussa B H Youdim, Orly Weinre. Beneficial behavioral, neurochemical and molecular effects of 1-(R)-aminoindan in aged mice. Neuropharmacology. vol 99. 2016-08-30. PMID:26087462. |
in addition, chronic ai treatment significantly enhanced expression levels of neurotrophins, including brain derived neurotrophic factor (bdnf) and nerve growth factor (ngf), tyrosine kinase- b (trk-b) receptor and synaptic plasticity markers, such as synapsin-1 and growth-associated protein-43 (gap-43) in the striatum and hippocampus in aged mice. |
2016-08-30 |
2023-08-13 |
mouse |
| Nabarun Chakraborty, James Meyerhoff, Aarti Gautam, Seid Muhie, Meskerem Jibitu, Thereza C M De Lima, Rasha Hammamieh, Marti Jet. Gene and stress history interplay in emergence of PTSD-like features. Behavioural brain research. vol 292. 2016-08-17. PMID:26025510. |
a group of genes (bdnf, ngf, zwint, cckbr, slc6a4, fkbp5) linked to ptsd and synaptic plasticity were significantly altered in c57bl/6j and balb/cj agg-e mice. |
2016-08-17 |
2023-08-13 |
mouse |
| Sören Enge, Monika Fleischhauer, Anne Gärtner, Andreas Reif, Klaus-Peter Lesch, Matthias Kliegel, Alexander Strobe. Brain-Derived Neurotrophic Factor (Val66Met) and Serotonin Transporter (5-HTTLPR) Polymorphisms Modulate Plasticity in Inhibitory Control Performance Over Time but Independent of Inhibitory Control Training. Frontiers in human neuroscience. vol 10. 2016-08-15. PMID:27524961. |
in the present study, a pre-post-follow-up design (n = 122) and a 3-weeks training of two response inhibition tasks (go/nogo and stop-signal) was employed and genetic variation (val66met) in the brain-derived neurotrophic factor (bdnf) promoting differentiation and activity-dependent synaptic plasticity was examined. |
2016-08-15 |
2023-08-13 |
Not clear |
| Jing-Hui Song, Jin-Tai Yu, Lan Ta. Brain-Derived Neurotrophic Factor in Alzheimer's Disease: Risk, Mechanisms, and Therapy. Molecular neurobiology. vol 52. issue 3. 2016-08-10. PMID:25354497. |
brain-derived neurotrophic factor (bdnf) has a neurotrophic support on neuron of central nervous system (cns) and is a key molecule in the maintenance of synaptic plasticity and memory storage in hippocampus. |
2016-08-10 |
2023-08-13 |
Not clear |
| Jürgen Tuvikene, Priit Pruunsild, Ester Orav, Eli-Eelika Esvald, Tõnis Timmus. AP-1 Transcription Factors Mediate BDNF-Positive Feedback Loop in Cortical Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 4. 2016-06-01. PMID:26818516. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophin family, regulates both survival and differentiation of several neuronal populations in the nervous system during development, as well as synaptic plasticity in the adult brain. |
2016-06-01 |
2023-08-13 |
human |
| Tomi Rantamäki, Ipek Yalci. Antidepressant drug action--From rapid changes on network function to network rewiring. Progress in neuro-psychopharmacology & biological psychiatry. vol 64. 2016-05-31. PMID:26066070. |
the delayed-onset of action of monoamine-based antidepressant drugs have been associated to their ability to slowly increase synaptic plasticity and neuronal excitability via altering neurotrophic signaling (synthesis of bdnf and activation of its receptor trkb), dematuration of gabaergic interneurons and inhibition of "breaks of plasticity". |
2016-05-31 |
2023-08-13 |
Not clear |
| Graciano Leal, Pedro M Afonso, Ivan L Salazar, Carlos B Duart. Regulation of hippocampal synaptic plasticity by BDNF. Brain research. vol 1621. 2016-05-23. PMID:25451089. |
regulation of hippocampal synaptic plasticity by bdnf. |
2016-05-23 |
2023-08-13 |
Not clear |
| Andrés Miguez, Gerardo García-Díaz Barriga, Verónica Brito, Marco Straccia, Albert Giralt, Silvia Ginés, Josep M Canals, Jordi Alberc. Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation. Human molecular genetics. vol 24. issue 17. 2016-05-11. PMID:26063761. |
in this view, we have investigated whether fty720 improves synaptic plasticity and memory in the r6/1 mouse model of hd, through regulation of bdnf signaling and astroglial reactivity. |
2016-05-11 |
2023-08-13 |
mouse |
| André Jerónimo-Santos, Sandra Henriques Vaz, Sara Parreira, Sofia Rapaz-Lérias, António P Caetano, Valérie Buée-Scherrer, Eero Castrén, Claudia A Valente, David Blum, Ana Maria Sebastião, Maria José Diógene. Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 9. 2016-05-10. PMID:24860020. |
brain-derived neurotrophic factor (bdnf) and its high-affinity full-length (fl) receptor, trkb-fl, play a central role in the nervous system by providing trophic support to neurons and regulating synaptic plasticity and memory. |
2016-05-10 |
2023-08-13 |
human |
| A L Negrón, M Beymer, G Yu, K A Warren, M Acosta-Martíne. Prolonged hyperglycemia & hyperinsulinemia increases BDNF mRNA expression in the posterior ventromedial hypothalamus and the dorsomedial hypothalamus of fed female rats. Neuroscience. vol 303. 2016-05-10. PMID:26166726. |
brain-derived neurotrophic factor (bdnf) plays a key role in neuronal development, synaptic plasticity, and the central control of energy homeostasis. |
2016-05-10 |
2023-08-13 |
rat |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
brain-derived neurotrophic factor (bdnf) has been shown to be important for neuronal survival and synaptic plasticity in the hippocampus in nonhuman animals. |
2016-05-09 |
2023-08-13 |
Not clear |
| Heather Bowling, Aditi Bhattacharya, Eric Klann, Moses V Cha. Deconstructing brain-derived neurotrophic factor actions in adult brain circuits to bridge an existing informational gap in neuro-cell biology. Neural regeneration research. vol 11. issue 3. 2016-04-29. PMID:27127458. |
brain-derived neurotrophic factor (bdnf) plays an important role in neurodevelopment, synaptic plasticity, learning and memory, and in preventing neurodegeneration. |
2016-04-29 |
2023-08-13 |
Not clear |
| Heather Bowling, Aditi Bhattacharya, Eric Klann, Moses V Cha. Deconstructing brain-derived neurotrophic factor actions in adult brain circuits to bridge an existing informational gap in neuro-cell biology. Neural regeneration research. vol 11. issue 3. 2016-04-29. PMID:27127458. |
this informational gap partly arises from the fact that the bulk of studies into the molecular actions of bdnf have been performed in dissociated neuronal cultures, while the majority of studies on synaptic plasticity, learning and memory were performed in acute brain slices or in vivo. |
2016-04-29 |
2023-08-13 |
Not clear |
| Christopher Galvin, Francis S Lee, Ipe Nina. Alteration of the Centromedial Amygdala Glutamatergic Synapses by the BDNF Val66Met Polymorphism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 9. 2016-04-26. PMID:25786582. |
unlike the wild-type mice that exhibited a potentiation of non-nmda receptor transmission following fear conditioning and a depotentiation upon fear extinction, bdnf(met/met) mice failed to show this experience-dependent synaptic plasticity in the cem neurons. |
2016-04-26 |
2023-08-13 |
mouse |
| Christopher Galvin, Francis S Lee, Ipe Nina. Alteration of the Centromedial Amygdala Glutamatergic Synapses by the BDNF Val66Met Polymorphism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 9. 2016-04-26. PMID:25786582. |
our results suggest that the elevated non-nmda receptor transmission, the suppression of nmda receptor transmission, and an impairment of synaptic plasticity in the cem neurons might contribute to the fear extinction deficit and increased anxiety-like symptoms in bdnf val66met carriers. |
2016-04-26 |
2023-08-13 |
mouse |
| Maria Tikhonova, Alexander V Kuliko. Antidepressant-Like Effects of Central BDNF Administration in Mice of Antidepressant Sensitive Catalepsy (ASC) Strain. The Chinese journal of physiology. vol 55. issue 4. 2016-04-23. PMID:23282170. |
bdnf also augmented mrna levels of arc gene encoding arc (activity-regulated cytoskeleton-associated) protein involved in bdnf-induced processes of neuronal and synaptic plasticity in hippocampus and prefrontal cortex. |
2016-04-23 |
2023-08-12 |
mouse |
| Xin-Chao Ji, Yuan-Yuan Dang, Hong-Yan Gao, Zhao-Tao Wang, Mou Gao, Yi Yang, Hong-Tian Zhang, Ru-Xiang X. Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice. Cellular and molecular neurobiology. vol 35. issue 6. 2016-04-20. PMID:25840805. |
there is much evidence to suggest that brain-derived neurotrophic factor (bdnf) is a prominent candidate in promoting neuroprotection, axonal regeneration, and synaptic plasticity following spinal cord injury (sci). |
2016-04-20 |
2023-08-13 |
mouse |