| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
brain-derived neurotrophic factor (bdnf) has been shown to be important for neuronal survival and synaptic plasticity in the hippocampus in nonhuman animals. |
2016-05-09 |
2023-08-13 |
Not clear |
| Heather Bowling, Aditi Bhattacharya, Eric Klann, Moses V Cha. Deconstructing brain-derived neurotrophic factor actions in adult brain circuits to bridge an existing informational gap in neuro-cell biology. Neural regeneration research. vol 11. issue 3. 2016-04-29. PMID:27127458. |
brain-derived neurotrophic factor (bdnf) plays an important role in neurodevelopment, synaptic plasticity, learning and memory, and in preventing neurodegeneration. |
2016-04-29 |
2023-08-13 |
Not clear |
| Heather Bowling, Aditi Bhattacharya, Eric Klann, Moses V Cha. Deconstructing brain-derived neurotrophic factor actions in adult brain circuits to bridge an existing informational gap in neuro-cell biology. Neural regeneration research. vol 11. issue 3. 2016-04-29. PMID:27127458. |
this informational gap partly arises from the fact that the bulk of studies into the molecular actions of bdnf have been performed in dissociated neuronal cultures, while the majority of studies on synaptic plasticity, learning and memory were performed in acute brain slices or in vivo. |
2016-04-29 |
2023-08-13 |
Not clear |
| Christopher Galvin, Francis S Lee, Ipe Nina. Alteration of the Centromedial Amygdala Glutamatergic Synapses by the BDNF Val66Met Polymorphism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 9. 2016-04-26. PMID:25786582. |
unlike the wild-type mice that exhibited a potentiation of non-nmda receptor transmission following fear conditioning and a depotentiation upon fear extinction, bdnf(met/met) mice failed to show this experience-dependent synaptic plasticity in the cem neurons. |
2016-04-26 |
2023-08-13 |
mouse |
| Christopher Galvin, Francis S Lee, Ipe Nina. Alteration of the Centromedial Amygdala Glutamatergic Synapses by the BDNF Val66Met Polymorphism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 9. 2016-04-26. PMID:25786582. |
our results suggest that the elevated non-nmda receptor transmission, the suppression of nmda receptor transmission, and an impairment of synaptic plasticity in the cem neurons might contribute to the fear extinction deficit and increased anxiety-like symptoms in bdnf val66met carriers. |
2016-04-26 |
2023-08-13 |
mouse |
| Maria Tikhonova, Alexander V Kuliko. Antidepressant-Like Effects of Central BDNF Administration in Mice of Antidepressant Sensitive Catalepsy (ASC) Strain. The Chinese journal of physiology. vol 55. issue 4. 2016-04-23. PMID:23282170. |
bdnf also augmented mrna levels of arc gene encoding arc (activity-regulated cytoskeleton-associated) protein involved in bdnf-induced processes of neuronal and synaptic plasticity in hippocampus and prefrontal cortex. |
2016-04-23 |
2023-08-12 |
mouse |
| Xin-Chao Ji, Yuan-Yuan Dang, Hong-Yan Gao, Zhao-Tao Wang, Mou Gao, Yi Yang, Hong-Tian Zhang, Ru-Xiang X. Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice. Cellular and molecular neurobiology. vol 35. issue 6. 2016-04-20. PMID:25840805. |
there is much evidence to suggest that brain-derived neurotrophic factor (bdnf) is a prominent candidate in promoting neuroprotection, axonal regeneration, and synaptic plasticity following spinal cord injury (sci). |
2016-04-20 |
2023-08-13 |
mouse |
| Li Chen, Hong Pan, Ta Anh Tuan, Ai Ling Teh, Julia L MacIsaac, Sarah M Mah, Lisa M McEwen, Yue Li, Helen Chen, Birit F P Broekman, Jan Paul Buschdorf, Yap Seng Chong, Kenneth Kwek, Seang Mei Saw, Peter D Gluckman, Marielle V Fortier, Anne Rifkin-Graboi, Michael S Kobor, Anqi Qiu, Michael J Meaney, Joanna D Holbroo. Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes. Development and psychopathology. vol 27. issue 1. 2016-04-18. PMID:25640836. |
here we examined the influence of a variant in the brain-derived neurotropic factor (bdnf) gene (val66met), which underlies synaptic plasticity throughout the central nervous system, on the degree to which antenatal maternal anxiety associated with neonatal dna methylation. |
2016-04-18 |
2023-08-13 |
Not clear |
| Z Tunca, B Kıvırcık Akdede, A Özerdem, T Alkın, S Polat, D Ceylan, M Bayın, N Cengizçetin Kocuk, S Şimşek, H Resmi, P Aka. Diverse glial cell line-derived neurotrophic factor (GDNF) support between mania and schizophrenia: a comparative study in four major psychiatric disorders. European psychiatry : the journal of the Association of European Psychiatrists. vol 30. issue 2. 2016-04-07. PMID:25543333. |
brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) have essential roles in synaptic plasticity which is involved in pathogenesis and treatment of psychiatric disorders. |
2016-04-07 |
2023-08-13 |
Not clear |
| F Harrisberger, R Smieskova, A Schmidt, C Lenz, A Walter, K Wittfeld, H J Grabe, U E Lang, P Fusar-Poli, S Borgward. BDNF Val66Met polymorphism and hippocampal volume in neuropsychiatric disorders: A systematic review and meta-analysis. Neuroscience and biobehavioral reviews. vol 55. 2016-03-31. PMID:25956254. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin involved in neurogenesis and synaptic plasticity in the central nervous system, especially in the hippocampus, and has been implicated in the pathophysiology of several neuropsychiatric disorders. |
2016-03-31 |
2023-08-13 |
Not clear |
| Susan L Patterso. Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity. Neuropharmacology. vol 96. issue Pt A. 2016-03-16. PMID:25549562. |
immune dysregulation and cognitive vulnerability in the aging brain: interactions of microglia, il-1β, bdnf and synaptic plasticity. |
2016-03-16 |
2023-08-13 |
Not clear |
| Wen-Hai Sui, Shu-Hong Huang, Jue Wang, Qun Chen, Ting Liu, Zhe-Yu Che. Myosin Va mediates BDNF-induced postendocytic recycling of full-length TrkB and its translocation into dendritic spines. Journal of cell science. vol 128. issue 6. 2016-03-10. PMID:25632160. |
brain-derived neurotrophic factor (bdnf) plays an important role in neuronal survival, neurite outgrowth and synaptic plasticity by activating the receptor tropomyosin receptor kinase b (trkb, also known as ntrk2). |
2016-03-10 |
2023-08-13 |
Not clear |
| Christos Sidiropoulos, Kourosh Jafari-Khouzani, Hamid Soltanian-Zadeh, Panayiotis Mitsias, Panagiotis Alexopoulos, Tanja Richter-Schmidinger, Martin Reichel, Piotr Lewczuk, Arnd Doerfler, Johannes Kornhube. Influence of brain-derived neurotrophic factor and apolipoprotein E genetic variants on hemispheric and lateral ventricular volume of young healthy adults. Acta neuropsychiatrica. vol 23. issue 3. 2016-03-09. PMID:21701702. |
brain-derived neurotrophic factor (bdnf) and apolipoprotein e (apoe) are thought to be implicated in a variety of neuronal processes, including cell growth, resilience to noxious stimuli and synaptic plasticity. |
2016-03-09 |
2023-08-12 |
Not clear |
| Hye Jin Park, Seungheon Lee, Ji Wook Jung, Byeong C Kim, Jong Hoon Ryu, Dong Hyun Ki. Glucocorticoid- and long-term stress-induced aberrant synaptic plasticity are mediated by activation of the glucocorticoid receptor. Archives of pharmacal research. vol 38. issue 6. 2016-03-08. PMID:25564339. |
these results suggest that corticosterone and long-term stress induce aberrant synaptic plasticity, memory impairment, and reduction in the hippocampal bdnf level through gr activation. |
2016-03-08 |
2023-08-13 |
rat |
| Mark B Powers, Johnna L Medina, Stephanie Burns, Brooke Y Kauffman, Marie Monfils, Gordon J G Asmundson, Allison Diamond, Christa McIntyre, Jasper A J Smit. Exercise Augmentation of Exposure Therapy for PTSD: Rationale and Pilot Efficacy Data. Cognitive behaviour therapy. vol 44. issue 4. 2016-03-07. PMID:25706090. |
brain-derived neurotrophic factor (bdnf) is associated with synaptic plasticity, which is crucial for long-term learning and memory. |
2016-03-07 |
2023-08-13 |
human |
| I C Macedo, J R Rozisky, C Oliveira, C M Oliveira, G Laste, Y Nonose, V S Santos, P R Marques, M F M Ribeiro, W Caumo, I L S Torre. Chronic stress associated with hypercaloric diet changes the hippocampal BDNF levels in male Wistar rats. Neuropeptides. vol 51. 2016-03-04. PMID:25963531. |
on the other hand, brain-derived neurotrophic factor (bdnf) is widely expressed in all brain regions, particularly in the hypothalamus, where it has important effects on neuroprotection, synaptic plasticity, mammalian food intake-behavior, and energy metabolism. |
2016-03-04 |
2023-08-13 |
rat |
| Katsuya Ogata, Norihito Shintani, Atsuko Hayata-Takano, Toshihiko Kamo, Shintaro Higashi, Kaoru Seiriki, Hisae Momosaki, David Vaudry, Hubert Vaudry, Ludovic Galas, Atsushi Kasai, Kazuki Nagayasu, Takanobu Nakazawa, Ryota Hashimoto, Yukio Ago, Toshio Matsuda, Akemichi Baba, Hitoshi Hashimot. PACAP enhances axon outgrowth in cultured hippocampal neurons to a comparable extent as BDNF. PloS one. vol 10. issue 3. 2016-02-17. PMID:25807538. |
pituitary adenylate cyclase-activating polypeptide (pacap) exerts neurotrophic activities including modulation of synaptic plasticity and memory, hippocampal neurogenesis, and neuroprotection, most of which are shared with brain-derived neurotrophic factor (bdnf). |
2016-02-17 |
2023-08-13 |
Not clear |
| Bing Chen, Xin-Liang Ma, Zhao Geng, Shu-Hong Huang, Lu-Kai Zhai, Yun-Yun Guo, Zhe-Yu Che. Up-regulation of c-Jun NH2-terminal kinase-interacting protein 3 (JIP3) contributes to BDNF-enhanced neurotransmitter release. Journal of neurochemistry. vol 135. issue 3. 2016-02-10. PMID:26303065. |
brain-derived neurotrophic factor (bdnf) has been implicated in the potent modulation of synaptic plasticity at both pre-synaptic and post-synaptic sites. |
2016-02-10 |
2023-08-13 |
Not clear |
| Qing-Qing Li, Bao-Ming L. Brain-derived neurotrophic factor in the anterior cingulate cortex is involved in the formation of fear memory. Sheng li xue bao : [Acta physiologica Sinica]. vol 67. issue 5. 2016-02-10. PMID:26490062. |
brain-derived neurotrophic factor (bdnf), a small dimeric secretory protein, plays a vital role in activity-dependent synaptic plasticity, learning and memory. |
2016-02-10 |
2023-08-13 |
rat |
| Yeonghoon Son, Miyoung Yang, Sohi Kang, Sueun Lee, Jinwook Kim, Juhwan Kim, Seri Park, Joong-Sun Kim, Sung-Kee Jo, Uhee Jung, Taekyun Shin, Sung-Ho Kim, Hongbing Wang, Changjong Moo. Cranial irradiation regulates CREB-BDNF signaling and variant BDNF transcript levels in the mouse hippocampus. Neurobiology of learning and memory. vol 121. 2016-01-22. PMID:25792232. |
in the hippocampus, brain-derived neurotrophic factor (bdnf) plays roles in neurogenesis, neuronal survival, neuronal differentiation, and synaptic plasticity. |
2016-01-22 |
2023-08-13 |
mouse |