| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mayu Fukuda, Atsushi Takatori, Yohko Nakamura, Akiko Suganami, Tyuji Hoshino, Yutaka Tamura, Akira Nakagawar. Effects of novel small compounds targeting TrkB on neuronal cell survival and depression-like behavior. Neurochemistry international. vol 97. 2017-12-12. PMID:27166149. |
brain-derived neurotrophic factor (bdnf) and its high affinity receptor tyrosine kinase receptor b (trkb) are involved in neuronal survival, maintenance, differentiation and synaptic plasticity. |
2017-12-12 |
2023-08-13 |
mouse |
| Hsiao-Ying Wey, Tonya M Gilbert, Nicole R Zürcher, Angela She, Anisha Bhanot, Brendan D Taillon, Fredrick A Schroeder, Changing Wang, Stephen J Haggarty, Jacob M Hooke. Insights into neuroepigenetics through human histone deacetylase PET imaging. Science translational medicine. vol 8. issue 351. 2017-12-07. PMID:27510902. |
in human stem cell-derived neural progenitor cells, pharmacologic-level doses of martinostat induced changes in genes closely associated with synaptic plasticity, including bdnf (brain-derived neurotrophic factor) and syp (synaptophysin), as well as genes implicated in neurodegeneration, including grn (progranulin), at the transcript level, in concert with increased acetylation at both histone h3 lysine 9 and histone h4 lysine 12. |
2017-12-07 |
2023-08-13 |
human |
| G Leal, C R Bramham, C B Duart. BDNF and Hippocampal Synaptic Plasticity. Vitamins and hormones. vol 104. 2017-11-02. PMID:28215294. |
bdnf and hippocampal synaptic plasticity. |
2017-11-02 |
2023-08-13 |
Not clear |
| G Leal, C R Bramham, C B Duart. BDNF and Hippocampal Synaptic Plasticity. Vitamins and hormones. vol 104. 2017-11-02. PMID:28215294. |
such observations prompted the suggestion that bdnf may regulate activity-dependent forms of synaptic plasticity such as long-term potentiation (ltp), a sustained enhancement of excitatory synaptic efficacy thought to underlie learning and memory. |
2017-11-02 |
2023-08-13 |
Not clear |
| M Kojima, T Mizu. BDNF Propeptide: A Novel Modulator of Synaptic Plasticity. Vitamins and hormones. vol 104. 2017-11-02. PMID:28215295. |
bdnf propeptide: a novel modulator of synaptic plasticity. |
2017-11-02 |
2023-08-13 |
Not clear |
| M Kojima, T Mizu. BDNF Propeptide: A Novel Modulator of Synaptic Plasticity. Vitamins and hormones. vol 104. 2017-11-02. PMID:28215295. |
in this chapter, we focus on the bdnf propeptide, especially in synaptic plasticity, and discuss the role of this molecule in the brain. |
2017-11-02 |
2023-08-13 |
Not clear |
| A Travaglia, D La Mendol. Zinc Interactions With Brain-Derived Neurotrophic Factor and Related Peptide Fragments. Vitamins and hormones. vol 104. 2017-11-02. PMID:28215299. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin essential for neuronal development and survival, synaptic plasticity, and cognitive function. |
2017-11-02 |
2023-08-13 |
Not clear |
| C Sat. Releasing Mechanism of Neurotrophic Factors via Polysialic Acid. Vitamins and hormones. vol 104. 2017-11-02. PMID:28215308. |
among the different types of neurotrophins, brain-derived neurotrophic factor (bdnf) is involved in various brain functions, including memory consolidation, synaptic plasticity, and adult neurogenesis, and is therefore a key molecule for understanding comprehensive brain function and neurodevelopmental and psychiatric diseases. |
2017-11-02 |
2023-08-13 |
Not clear |
| Hui Chen, Marc Lombès, Damien Le Menue. Glucocorticoid receptor represses brain-derived neurotrophic factor expression in neuron-like cells. Molecular brain. vol 10. issue 1. 2017-10-30. PMID:28403881. |
brain-derived neurotrophic factor (bdnf) is involved in many functions such as neuronal growth, survival, synaptic plasticity and memorization. |
2017-10-30 |
2023-08-13 |
mouse |
| Monika Wilkosc, Anita Markowska, Ludmila Zajac-Lamparska, Maria Skibinska, Agnieszka Szalkowska, Aleksander Araszkiewic. A Lack of Correlation between Brain-Derived Neurotrophic Factor Serum Level and Verbal Memory Performance in Healthy Polish Population. Frontiers in neural circuits. vol 10. 2017-10-23. PMID:27242447. |
brain derived neurotrophic factor (bdnf) is considered to be connected with memory and learning through the processes of long term synaptic potentiation and synaptic plasticity. |
2017-10-23 |
2023-08-13 |
human |
| Amene Saghazadeh, Nima Rezae. Brain-Derived Neurotrophic Factor Levels in Autism: A Systematic Review and Meta-Analysis. Journal of autism and developmental disorders. vol 47. issue 4. 2017-10-20. PMID:28138831. |
brain-derived neurotrophic factor (bdnf) plays an important role in activity-dependent synaptic plasticity. |
2017-10-20 |
2023-08-13 |
human |
| Z Hawi, T D R Cummins, J Tong, M Arcos-Burgos, Q Zhao, N Matthews, D P Newman, B Johnson, A Vance, H S Heussler, F Levy, S Easteal, N R Wray, E Kenny, D Morris, L Kent, M Gill, M A Bellgrov. Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study. Molecular psychiatry. vol 22. issue 4. 2017-10-10. PMID:27457811. |
our results implicate bdnf as a genetic risk factor for adhd, potentially by virtue of its critical role in neurodevelopment and synaptic plasticity. |
2017-10-10 |
2023-08-13 |
Not clear |
| Warren Caldwell, Opal A McInnis, Robyn J McQuaid, Gele Liu, John D Stead, Hymie Anisman, Shawn Hayle. The Role of the Val66Met Polymorphism of the Brain Derived Neurotrophic Factor Gene in Coping Strategies Relevant to Depressive Symptoms. PloS one. vol 8. issue 6. 2017-10-06. PMID:23824678. |
disturbances of brain derived neurotrophic factor (bdnf) signalling have been implicated in the evolution of depression, which likely arises, in part, as a result of diminished synaptic plasticity. |
2017-10-06 |
2023-08-12 |
Not clear |
| Elisabetta Tronci, Francesco Napolitano, Ana Muñoz, Camino Fidalgo, Francesca Rossi, Anders Björklund, Alessandro Usiello, Manolo Cart. BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats. Experimental neurology. vol 297. 2017-10-05. PMID:28757258. |
in addition to its role in neuronal survival, the brain neurotrophic factor (bdnf) has been shown to influence serotonin transmission and synaptic plasticity, events strongly implicated in the appearance of l-dopa-induced dyskinesia (lid), a motor complication occurring in parkinsonian patients after long-term treatment with the dopamine precursor. |
2017-10-05 |
2023-08-13 |
rat |
| R D Idell, G Florova, A A Komissarov, S Shetty, R B S Girard, S Idel. The fibrinolytic system: A new target for treatment of depression with psychedelics. Medical hypotheses. vol 100. 2017-10-02. PMID:28236848. |
tissue plasminogen activator (tpa) is a key factor that not only promotes fibrinolysis via the activation of plasminogen, but also contributes to regulation of synaptic plasticity and neurogenesis through plasmin-mediated activation of a probrain derived neurotrophic factor (bdnf) to mature bdnf. |
2017-10-02 |
2023-08-13 |
Not clear |
| Sandra M Garraway, J Russell Hui. Spinal Plasticity and Behavior: BDNF-Induced Neuromodulation in Uninjured and Injured Spinal Cord. Neural plasticity. vol 2016. 2017-09-20. PMID:27721996. |
since its discovery over three decades ago, bdnf has been identified as an important regulator of neuronal development, synaptic transmission, and cellular and synaptic plasticity and has been shown to function in the formation and maintenance of certain forms of memory. |
2017-09-20 |
2023-08-13 |
Not clear |
| A R Graves, S J Moore, N Spruston, A K Tryba, C C Kaczorowsk. Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons. Journal of neurophysiology. vol 116. issue 2. 2017-09-07. PMID:27146982. |
furthermore, while endogenous bdnf was necessary for the induction of synaptic plasticity in both cell types, bdnf enhanced intrinsic plasticity in one class of pyramidal neurons yet suppressed intrinsic plasticity in the other. |
2017-09-07 |
2023-08-13 |
Not clear |
| C M Y Chau, I L Cepeda, A M Devlin, J Weinberg, R E Gruna. The Val66Met brain-derived neurotrophic factor gene variant interacts with early pain exposure to predict cortisol dysregulation in 7-year-old children born very preterm: Implications for cognition. Neuroscience. vol 342. 2017-09-05. PMID:26318333. |
brain-derived neurotrophic factor (bdnf) which is important in synaptic plasticity and cognitive functions is reduced by stress. |
2017-09-05 |
2023-08-13 |
Not clear |
| Yun-Yun Guo, Yi Lu, Yuan Zheng, Xiao-Rong Chen, Jun-Lu Dong, Rong-Rong Yuan, Shu-Hong Huang, Hui Yu, Yue Wang, Zhe-Yu Chen, Bo S. Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) Promotes Hippocampus-Dependent Memory via Its Deubiquitinating Effect on TrkB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 25. 2017-08-14. PMID:28500221. |
multiple studies have established that brain-derived neurotrophic factor (bdnf) plays a critical role in the regulation of synaptic plasticity via its receptor, trkb. |
2017-08-14 |
2023-08-13 |
mouse |
| Pietro Cacialli, Marie-Madeleine Gueguen, Pascal Coumailleau, Livia D'Angelo, Olivier Kah, Carla Lucini, Elisabeth Pellegrin. BDNF Expression in Larval and Adult Zebrafish Brain: Distribution and Cell Identification. PloS one. vol 11. issue 6. 2017-07-24. PMID:27336917. |
bdnf plays significant roles in neurogenesis, neuronal maturation and/or synaptic plasticity and is involved in cognitive functions such as learning and memory. |
2017-07-24 |
2023-08-13 |
zebrafish |