| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Sat. Releasing Mechanism of Neurotrophic Factors via Polysialic Acid. Vitamins and hormones. vol 104. 2017-11-02. PMID:28215308. |
among the different types of neurotrophins, brain-derived neurotrophic factor (bdnf) is involved in various brain functions, including memory consolidation, synaptic plasticity, and adult neurogenesis, and is therefore a key molecule for understanding comprehensive brain function and neurodevelopmental and psychiatric diseases. |
2017-11-02 |
2023-08-13 |
Not clear |
| Hui Chen, Marc Lombès, Damien Le Menue. Glucocorticoid receptor represses brain-derived neurotrophic factor expression in neuron-like cells. Molecular brain. vol 10. issue 1. 2017-10-30. PMID:28403881. |
brain-derived neurotrophic factor (bdnf) is involved in many functions such as neuronal growth, survival, synaptic plasticity and memorization. |
2017-10-30 |
2023-08-13 |
mouse |
| Monika Wilkosc, Anita Markowska, Ludmila Zajac-Lamparska, Maria Skibinska, Agnieszka Szalkowska, Aleksander Araszkiewic. A Lack of Correlation between Brain-Derived Neurotrophic Factor Serum Level and Verbal Memory Performance in Healthy Polish Population. Frontiers in neural circuits. vol 10. 2017-10-23. PMID:27242447. |
brain derived neurotrophic factor (bdnf) is considered to be connected with memory and learning through the processes of long term synaptic potentiation and synaptic plasticity. |
2017-10-23 |
2023-08-13 |
human |
| Amene Saghazadeh, Nima Rezae. Brain-Derived Neurotrophic Factor Levels in Autism: A Systematic Review and Meta-Analysis. Journal of autism and developmental disorders. vol 47. issue 4. 2017-10-20. PMID:28138831. |
brain-derived neurotrophic factor (bdnf) plays an important role in activity-dependent synaptic plasticity. |
2017-10-20 |
2023-08-13 |
human |
| Z Hawi, T D R Cummins, J Tong, M Arcos-Burgos, Q Zhao, N Matthews, D P Newman, B Johnson, A Vance, H S Heussler, F Levy, S Easteal, N R Wray, E Kenny, D Morris, L Kent, M Gill, M A Bellgrov. Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study. Molecular psychiatry. vol 22. issue 4. 2017-10-10. PMID:27457811. |
our results implicate bdnf as a genetic risk factor for adhd, potentially by virtue of its critical role in neurodevelopment and synaptic plasticity. |
2017-10-10 |
2023-08-13 |
Not clear |
| Warren Caldwell, Opal A McInnis, Robyn J McQuaid, Gele Liu, John D Stead, Hymie Anisman, Shawn Hayle. The Role of the Val66Met Polymorphism of the Brain Derived Neurotrophic Factor Gene in Coping Strategies Relevant to Depressive Symptoms. PloS one. vol 8. issue 6. 2017-10-06. PMID:23824678. |
disturbances of brain derived neurotrophic factor (bdnf) signalling have been implicated in the evolution of depression, which likely arises, in part, as a result of diminished synaptic plasticity. |
2017-10-06 |
2023-08-12 |
Not clear |
| Elisabetta Tronci, Francesco Napolitano, Ana Muñoz, Camino Fidalgo, Francesca Rossi, Anders Björklund, Alessandro Usiello, Manolo Cart. BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats. Experimental neurology. vol 297. 2017-10-05. PMID:28757258. |
in addition to its role in neuronal survival, the brain neurotrophic factor (bdnf) has been shown to influence serotonin transmission and synaptic plasticity, events strongly implicated in the appearance of l-dopa-induced dyskinesia (lid), a motor complication occurring in parkinsonian patients after long-term treatment with the dopamine precursor. |
2017-10-05 |
2023-08-13 |
rat |
| R D Idell, G Florova, A A Komissarov, S Shetty, R B S Girard, S Idel. The fibrinolytic system: A new target for treatment of depression with psychedelics. Medical hypotheses. vol 100. 2017-10-02. PMID:28236848. |
tissue plasminogen activator (tpa) is a key factor that not only promotes fibrinolysis via the activation of plasminogen, but also contributes to regulation of synaptic plasticity and neurogenesis through plasmin-mediated activation of a probrain derived neurotrophic factor (bdnf) to mature bdnf. |
2017-10-02 |
2023-08-13 |
Not clear |
| Sandra M Garraway, J Russell Hui. Spinal Plasticity and Behavior: BDNF-Induced Neuromodulation in Uninjured and Injured Spinal Cord. Neural plasticity. vol 2016. 2017-09-20. PMID:27721996. |
since its discovery over three decades ago, bdnf has been identified as an important regulator of neuronal development, synaptic transmission, and cellular and synaptic plasticity and has been shown to function in the formation and maintenance of certain forms of memory. |
2017-09-20 |
2023-08-13 |
Not clear |
| A R Graves, S J Moore, N Spruston, A K Tryba, C C Kaczorowsk. Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons. Journal of neurophysiology. vol 116. issue 2. 2017-09-07. PMID:27146982. |
furthermore, while endogenous bdnf was necessary for the induction of synaptic plasticity in both cell types, bdnf enhanced intrinsic plasticity in one class of pyramidal neurons yet suppressed intrinsic plasticity in the other. |
2017-09-07 |
2023-08-13 |
Not clear |
| C M Y Chau, I L Cepeda, A M Devlin, J Weinberg, R E Gruna. The Val66Met brain-derived neurotrophic factor gene variant interacts with early pain exposure to predict cortisol dysregulation in 7-year-old children born very preterm: Implications for cognition. Neuroscience. vol 342. 2017-09-05. PMID:26318333. |
brain-derived neurotrophic factor (bdnf) which is important in synaptic plasticity and cognitive functions is reduced by stress. |
2017-09-05 |
2023-08-13 |
Not clear |
| Yun-Yun Guo, Yi Lu, Yuan Zheng, Xiao-Rong Chen, Jun-Lu Dong, Rong-Rong Yuan, Shu-Hong Huang, Hui Yu, Yue Wang, Zhe-Yu Chen, Bo S. Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) Promotes Hippocampus-Dependent Memory via Its Deubiquitinating Effect on TrkB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 25. 2017-08-14. PMID:28500221. |
multiple studies have established that brain-derived neurotrophic factor (bdnf) plays a critical role in the regulation of synaptic plasticity via its receptor, trkb. |
2017-08-14 |
2023-08-13 |
mouse |
| Pietro Cacialli, Marie-Madeleine Gueguen, Pascal Coumailleau, Livia D'Angelo, Olivier Kah, Carla Lucini, Elisabeth Pellegrin. BDNF Expression in Larval and Adult Zebrafish Brain: Distribution and Cell Identification. PloS one. vol 11. issue 6. 2017-07-24. PMID:27336917. |
bdnf plays significant roles in neurogenesis, neuronal maturation and/or synaptic plasticity and is involved in cognitive functions such as learning and memory. |
2017-07-24 |
2023-08-13 |
zebrafish |
| Liang Zhong, Foquan Luo, Weilu Zhao, Yunlin Feng, Liuqin Wu, Jiamei Lin, Tianyin Liu, Shengqiang Wang, Xuexue You, Wei Zhan. Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspring via the BDNF-TrkB signalling pathway. Journal of cellular and molecular medicine. vol 20. issue 10. 2017-07-11. PMID:27297627. |
synaptophysin provides the structural basis for synaptic plasticity and depends on bdnf processing and subsequent trkb signalling. |
2017-07-11 |
2023-08-13 |
rat |
| Deqiang Jing, Francis S Lee, Ipe Nina. The BDNF Val66Met polymorphism enhances glutamatergic transmission but diminishes activity-dependent synaptic plasticity in the dorsolateral striatum. Neuropharmacology. vol 112. issue Pt A. 2017-07-11. PMID:27378336. |
the bdnf val66met polymorphism enhances glutamatergic transmission but diminishes activity-dependent synaptic plasticity in the dorsolateral striatum. |
2017-07-11 |
2023-08-13 |
mouse |
| Veronica Begni, Marco Andrea Riva, Annamaria Cattane. Cellular and molecular mechanisms of the brain-derived neurotrophic factor in physiological and pathological conditions. Clinical science (London, England : 1979). vol 131. issue 2. 2017-07-06. PMID:28011898. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that plays a key role in the central nervous system, promoting synaptic plasticity, neurogenesis and neuroprotection. |
2017-07-06 |
2023-08-13 |
Not clear |
| Veronica Begni, Marco Andrea Riva, Annamaria Cattane. Cellular and molecular mechanisms of the brain-derived neurotrophic factor in physiological and pathological conditions. Clinical science (London, England : 1979). vol 131. issue 2. 2017-07-06. PMID:28011898. |
bdnf exerts a wide range of effects on neuronal function, including the modulation of activity-dependent synaptic plasticity and neurogenesis. |
2017-07-06 |
2023-08-13 |
Not clear |
| Mengya Xing, Qingna Sun, Yiyi Wang, Yan Cheng, Nan Zhan. Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model. Brain research. vol 1642. 2017-06-28. PMID:27086971. |
the results indicate that hsya may enhance the endogenous expression of bdnf and glun2b, which are associated with the synaptic plasticity of the hippocampus, and may improve spatial learning and memory abilities in a rat model of vad. |
2017-06-28 |
2023-08-13 |
rat |
| Stefanie Traub, Heiko Stahl, Holger Rosenbrock, Eric Simon, Lore Florin, Lisa Hospach, Stefan Hörer, Ralf Heilke. Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons. The Journal of pharmacology and experimental therapeutics. vol 361. issue 3. 2017-06-13. PMID:28351853. |
brain-derived neurotrophic factor (bdnf) is a central modulator of neuronal development and synaptic plasticity in the central nervous system. |
2017-06-13 |
2023-08-13 |
human |
| Tapan Behl, Anita Kotwan. Downregulated Brain-Derived Neurotrophic Factor-Induced Oxidative Stress in the Pathophysiology of Diabetic Retinopathy. Canadian journal of diabetes. vol 41. issue 2. 2017-05-31. PMID:27913110. |
brain-derived neurotrophic factor (bdnf), a member of neurotrophin growth factor family, physiologically mediates induction of neurogenesis and neuronal differentiation, promotes neuronal growth and survival and maintains synaptic plasticity and neuronal interconnections. |
2017-05-31 |
2023-08-13 |
Not clear |