| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emi Satomura, Hajime Baba, Yoshiyuki Nakano, Hitoshi Maeshima, Toshihito Suzuki, Heii Ara. Correlations between brain-derived neurotrophic factor and clinical symptoms in medicated patients with major depression. Journal of affective disorders. vol 135. issue 1-3. 2012-01-25. PMID:21774990. |
brain-derived neurotrophic factor (bdnf) is a member of the nerve growth factor family and plays a critical role in growth, differentiation, maintenance and synaptic plasticity of neuronal systems. |
2012-01-25 |
2023-08-12 |
Not clear |
| C Robinet, L Pelleri. Brain-derived neurotrophic factor enhances the hippocampal expression of key postsynaptic proteins in vivo including the monocarboxylate transporter MCT2. Neuroscience. vol 192. 2012-01-18. PMID:21736920. |
brain-derived neurotrophic factor (bdnf) promotes synaptic plasticity via an enhancement in expression of specific synaptic proteins. |
2012-01-18 |
2023-08-12 |
mouse |
| C Robinet, L Pelleri. Brain-derived neurotrophic factor enhances the hippocampal expression of key postsynaptic proteins in vivo including the monocarboxylate transporter MCT2. Neuroscience. vol 192. 2012-01-18. PMID:21736920. |
to investigate in vivo whether bdnf can modulate the expression of mct2 as well as other proteins involved in synaptic plasticity, acute injection of bdnf was performed in mouse dorsal hippocampal ca1 area. |
2012-01-18 |
2023-08-12 |
mouse |
| Kurt Gottmann, Thomas Mittmann, Volkmar Lessman. BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses. Experimental brain research. vol 199. issue 3-4. 2012-01-17. PMID:19777221. |
in addition, bdnf appears to be also an instructive factor for activity-dependent long-term synaptic plasticity. |
2012-01-17 |
2023-08-12 |
Not clear |
| Kurt Gottmann, Thomas Mittmann, Volkmar Lessman. BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses. Experimental brain research. vol 199. issue 3-4. 2012-01-17. PMID:19777221. |
this review attempts to summarize the current knowledge in synaptic secretion and synaptic action of bdnf, including both permissive and instructive effects of bdnf in synaptic plasticity. |
2012-01-17 |
2023-08-12 |
Not clear |
| Tadahiro Numakawa, Misty Richards, Naoki Adachi, Soichiro Kishi, Hiroshi Kunugi, Kazuo Hashid. MicroRNA function and neurotrophin BDNF. Neurochemistry international. vol 59. issue 5. 2012-01-12. PMID:21723895. |
on the other hand, numerous studies indicate that bdnf (brain-derived neurotrophic factor), one of the neurotrophins, is essential for a variety of neuronal aspects such as cell differentiation, survival, and synaptic plasticity in the central nervous system (cns). |
2012-01-12 |
2023-08-12 |
Not clear |
| Nader Perrou. Suicidal ideation during antidepressant treatment: do genetic predictors exist? CNS drugs. vol 25. issue 6. 2011-12-30. PMID:21649447. |
in this perspective, several genetic predictors have been highlighted, the majority of which relate to common mechanisms of antidepressant action: genes involved in the neurotrophic and synaptic plasticity systems (creb1, and bdnf and its receptor ntrk2), noradrenergic system (adra2a), glutamatergic system (gria3, grik2 and gda), inflammatory and hypothalamic-pituitary-adrenal (hpa) axis systems (il28ra and fkbp5) and in other brain functions (papln, apoo, kcnip4 and elp3). |
2011-12-30 |
2023-08-12 |
Not clear |
| Fernando Gomez-Pinill. Collaborative effects of diet and exercise on cognitive enhancement. Nutrition and health. vol 20. issue 3-4. 2011-12-20. PMID:22141190. |
omega 3 fatty acids and curcumin elevate levels of molecules important for synaptic plasticity such as brain-derived neurotrophic factor (bdnf), thus benefiting normal brain function and recovery events following brain insults. |
2011-12-20 |
2023-08-12 |
Not clear |
| Flurin Cathomas, Christian Vogler, Jessica C Euler-Sigmund, Dominique J-F de Quervain, Andreas Papassotiropoulo. Fine-mapping of the brain-derived neurotrophic factor (BDNF) gene supports an association of the Val66Met polymorphism with episodic memory. The international journal of neuropsychopharmacology. vol 13. issue 8. 2011-12-19. PMID:20482942. |
brain-derived neurotrophic factor (bdnf) plays an important role in hippocampal synaptic plasticity and long-term potentiation. |
2011-12-19 |
2023-08-12 |
Not clear |
| Kang Zheng, Juan Ji An, Feng Yang, Weifeng Xu, Zhi-Qing David Xu, Jianyoung Wu, Tomas G M Hökfelt, André Fisahn, Baoji Xu, Bai L. TrkB signaling in parvalbumin-positive interneurons is critical for gamma-band network synchronization in hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 41. 2011-12-13. PMID:21949401. |
although brain-derived neurotrophic factor (bdnf) is known to regulate circuit development and synaptic plasticity, its exact role in neuronal network activity remains elusive. |
2011-12-13 |
2023-08-12 |
mouse |
| Nashat Abumaria, Bin Yin, Ling Zhang, Xiang-Yao Li, Tao Chen, Giannina Descalzi, Liangfang Zhao, Matae Ahn, Lin Luo, Chen Ran, Min Zhuo, Guosong Li. Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 42. 2011-12-08. PMID:22016520. |
in intact animals, elevation of brain magnesium increased nmda receptors (nmdars) signaling, bdnf expression, density of presynaptic puncta, and synaptic plasticity in the pfc but, interestingly, not in the basolateral amygdala. |
2011-12-08 |
2023-08-12 |
rat |
| Brisa Simões Fernandes, Clarissa Severino Gama, Keila Maria Ceresér, Lakshmi N Yatham, Gabriel Rodrigo Fries, Gabriela Colpo, David de Lucena, Mauricio Kunz, Fabiano Alves Gomes, Flavio Kapczinsk. Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis. Journal of psychiatric research. vol 45. issue 8. 2011-11-29. PMID:21550050. |
brain-derived neurotrophic factor (bdnf) plays a central role in synaptic plasticity and neurogenesis. |
2011-11-29 |
2023-08-12 |
human |
| Verna Louhivuori, Annalisa Vicario, Marko Uutela, Tomi Rantamäki, Lauri M Louhivuori, Eero Castrén, Enrico Tongiorgi, Karl E Akerman, Maija L Castré. BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse. Neurobiology of disease. vol 41. issue 2. 2011-11-22. PMID:21047554. |
in addition, bdnf protein levels were increased in the hippocampus but reduced in the cortex of fmr1-ko mice in line with regional differences of synaptic plasticity in the brain of fmr1-ko mice. |
2011-11-22 |
2023-08-12 |
mouse |
| Araceli Martínez-Moreno, Luis F Rodríguez-Durán, Martha L Escoba. Late Protein Synthesis-Dependent Phases in CTA Long-Term Memory: BDNF Requirement. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:21960964. |
brain-derived neurotrophic factor (bdnf) is an essential protein synthesis product that has emerged as one of the most potent molecular mediators for long-term synaptic plasticity. |
2011-11-10 |
2023-08-12 |
rat |
| Benchawanna Soontornniyomkij, Ian P Everall, Gursharan Chana, Ming T Tsuang, Cristian L Achim, Virawudh Soontornniyomki. Tyrosine kinase B protein expression is reduced in the cerebellum of patients with bipolar disorder. Journal of affective disorders. vol 133. issue 3. 2011-11-04. PMID:21612826. |
brain-derived neurotrophic factor (bdnf)-induced activation of tyrosine kinase b (trkb) is essential to synaptic plasticity. |
2011-11-04 |
2023-08-12 |
Not clear |
| Sarah Felice Evans, Krithi Irmady, Katya Ostrow, Taeho Kim, Anders Nykjaer, Paul Saftig, Carl Blobel, Barbara L Hempstea. Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation. The Journal of biological chemistry. vol 286. issue 34. 2011-10-18. PMID:21730062. |
brain-derived neurotrophic factor (bdnf) regulates neuronal differentiation, synaptic plasticity, and morphology, and modest changes in bdnf levels results in complex behavioral phenotypes. |
2011-10-18 |
2023-08-12 |
Not clear |
| Ruth M Barrientos, Matthew G Frank, Nicole Y Crysdale, Timothy R Chapman, Jared T Ahrendsen, Heidi E W Day, Serge Campeau, Linda R Watkins, Susan L Patterson, Steven F Maie. Little exercise, big effects: reversing aging and infection-induced memory deficits, and underlying processes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 32. 2011-10-04. PMID:21832188. |
among the outcomes of this exaggerated neuroinflammatory response are impairments in synaptic plasticity and reductions of brain-derived neurotrophic factor (bdnf), both of which have been associated with cognitive impairments. |
2011-10-04 |
2023-08-12 |
rat |
| Anders B Klein, Rebecca Williamson, Martin A Santini, Christoffer Clemmensen, Anders Ettrup, Maribel Rios, Gitte M Knudsen, Susana Azna. Blood BDNF concentrations reflect brain-tissue BDNF levels across species. The international journal of neuropsychopharmacology. vol 14. issue 3. 2011-09-19. PMID:20604989. |
brain-derived neurotrophic factor (bdnf) is involved in synaptic plasticity, neuronal differentiation and survival of neurons. |
2011-09-19 |
2023-08-12 |
mouse |
| Christoph Laske, Konstantinos Stellos, Nadine Hoffmann, Elke Stransky, Guido Straten, Gerhard W Eschweiler, Thomas Leyh. Higher BDNF serum levels predict slower cognitive decline in Alzheimer's disease patients. The international journal of neuropsychopharmacology. vol 14. issue 3. 2011-09-19. PMID:20860877. |
the neurotrophin brain-derived neurotrophic factor (bdnf) plays a critical role in neuronal survival, synaptic plasticity, and memory. |
2011-09-19 |
2023-08-12 |
Not clear |
| Mona El-Sayed, Jacob Hofman-Bang, Jens D Mikkelse. Effect of brain-derived neurotrophic factor on activity-regulated cytoskeleton-associated protein gene expression in primary frontal cortical neurons. Comparison with NMDA and AMPA. European journal of pharmacology. vol 660. issue 2-3. 2011-09-06. PMID:21515256. |
these results demonstrate bdnf to be a highly potent and efficient inducer of arc gene expression in vitro, emphasizing the role of this growth factor in synaptic plasticity in the frontal cortex. |
2011-09-06 |
2023-08-12 |
rat |