Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yogesh Dwived. Brain-derived neurotrophic factor: role in depression and suicide. Neuropsychiatric disease and treatment. vol 5. 2011-04-26. PMID:19721723. |
brain-derived neurotrophic factor (bdnf), one of the major neurotrophic factors, plays an important role in the maintenance and survival of neurons and in synaptic plasticity. |
2011-04-26 |
2023-08-12 |
Not clear |
Hui Yu, Zhe-yu Che. The role of BDNF in depression on the basis of its location in the neural circuitry. Acta pharmacologica Sinica. vol 32. issue 1. 2011-04-25. PMID:21131999. |
brain-derived neurotrophic factor (bdnf) is broadly expressed in the developing and adult mammalian brain and has been implicated in development, neural regeneration, synaptic transmission, synaptic plasticity and neurogenesis. |
2011-04-25 |
2023-08-12 |
Not clear |
Yen-Ching Wu, Rebecca Williamson, Zhi Li, Annalisa Vicario, Jerry Xu, Masataka Kasai, Yijuang Chern, Enrico Tongiorgi, Jay M Baraba. Dendritic trafficking of brain-derived neurotrophic factor mRNA: regulation by translin-dependent and -independent mechanisms. Journal of neurochemistry. vol 116. issue 6. 2011-04-15. PMID:21198640. |
dendritic trafficking and translation of brain-derived neurotrophic factor (bdnf) transcripts play a key role in mediating synaptic plasticity. |
2011-04-15 |
2023-08-12 |
mouse |
Tatiana Adasme, Paola Haeger, Andrea C Paula-Lima, Italo Espinoza, M Mercedes Casas-Alarcón, M Angélica Carrasco, Cecilia Hidalg. Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 7. 2011-04-14. PMID:21282625. |
along with calcium signals, brain-derived neurotrophic factor (bdnf) is a key signaling molecule for hippocampal synaptic plasticity and spatial memory. |
2011-04-14 |
2023-08-12 |
rat |
Antonio Lucio Teixeira, Izabela Guimarães Barbosa, Breno Satler Diniz, Arthur Kumme. Circulating levels of brain-derived neurotrophic factor: correlation with mood, cognition and motor function. Biomarkers in medicine. vol 4. issue 6. 2011-04-11. PMID:21133708. |
brain-derived neurotrophic factor (bdnf) is the most widely distributed neurotrophin in the cns, where it plays several pivotal roles in synaptic plasticity and neuronal survival. |
2011-04-11 |
2023-08-12 |
Not clear |
Diana V Castillo, Martha L Escoba. A role for MAPK and PI-3K signaling pathways in brain-derived neurotrophic factor modification of conditioned taste aversion retention. Behavioural brain research. vol 217. issue 1. 2011-04-01. PMID:20974194. |
brain-derived neurotrophic factor (bdnf) has emerged as an important molecular mediator of synaptic plasticity. |
2011-04-01 |
2023-08-12 |
rat |
Neslihan Aygun Kocabas, Irina Antonijevic, Carole Faghel, Carlos Forray, Siegfried Kasper, Yves Lecrubier, Sylvie Linotte, Isabelle Massat, Julien Mendlewicz, Magali Noro, Stuart Montgomery, Pierre Oswald, Lenore Snyder, Joseph Zohar, Daniel Souer. Brain-derived neurotrophic factor gene polymorphisms: influence on treatment response phenotypes of major depressive disorder. International clinical psychopharmacology. vol 26. issue 1. 2011-03-18. PMID:21188787. |
brain-derived neurotrophic factor (bdnf), a member of the nerve growth factor family of neurotrophins, has pivotal roles in neuronal survival, proliferation, and synaptic plasticity in the brain. |
2011-03-18 |
2023-08-12 |
Not clear |
Ana Rita Santos, Diogo Comprido, Carlos B Duart. Regulation of local translation at the synapse by BDNF. Progress in neurobiology. vol 92. issue 4. 2011-03-15. PMID:20713125. |
the neurotrophin brain-derived neurotrophic factor (bdnf) plays a key role in synaptic plasticity, in part due to changes in local protein synthesis. |
2011-03-15 |
2023-08-12 |
Not clear |
Ana Rita Santos, Diogo Comprido, Carlos B Duart. Regulation of local translation at the synapse by BDNF. Progress in neurobiology. vol 92. issue 4. 2011-03-15. PMID:20713125. |
this review highlights the recent advances in the understanding of the diversity of mechanisms that contribute to the regulation of the synaptic proteome by bdnf, which may account for its role in synaptic plasticity. |
2011-03-15 |
2023-08-12 |
Not clear |
Patricia F Kao, David A Davis, Meredith G Banigan, Charles R Vanderburg, Sudha Seshadri, Ivana Delall. Modulators of cytoskeletal reorganization in CA1 hippocampal neurons show increased expression in patients at mid-stage Alzheimer's disease. PloS one. vol 5. issue 10. 2011-03-07. PMID:20967212. |
moreover, the increased expression of capzb2 mrna in ca1 pyramidal neurons in ad bb iii-iv is accompanied by an increased mrna expression of brain derived neurotrophic factor (bdnf) receptor tyrosine kinase b (trkb), mediator of synaptic plasticity in hippocampal neurons. |
2011-03-07 |
2023-08-12 |
Not clear |
Andrea Antal, Leila Chaieb, Vera Moliadze, Katia Monte-Silva, Csaba Poreisz, Nivethida Thirugnanasambandam, Michael A Nitsche, Moneef Shoukier, Harald Ludwig, Walter Paulu. Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans. Brain stimulation. vol 3. issue 4. 2011-03-04. PMID:20965453. |
the brain-derived neurotrophic factor (bdnf) gene is involved in mechanisms of synaptic plasticity in the adult brain. |
2011-03-04 |
2023-08-12 |
human |
Frank Krueger, Matteo Pardini, Edward D Huey, Vanessa Raymont, Jeffrey Solomon, Robert H Lipsky, Colin A Hodgkinson, David Goldman, Jordan Grafma. The role of the Met66 brain-derived neurotrophic factor allele in the recovery of executive functioning after combat-related traumatic brain injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 2. 2011-02-22. PMID:21228168. |
brain-derived neurotrophic factor (bdnf), a member of the neurotrophin family, promotes survival and synaptic plasticity in the human brain. |
2011-02-22 |
2023-08-12 |
human |
Nicola Kuczewski, Christophe Porcher, Jean-Luc Gaiars. Activity-dependent dendritic secretion of brain-derived neurotrophic factor modulates synaptic plasticity. The European journal of neuroscience. vol 32. issue 8. 2011-01-28. PMID:20880359. |
although the importance of bdnf in synaptic plasticity has been clearly established, direct evidence for a specific contribution of the activity-dependent dendritic secretion of bdnf has been difficult to obtain. |
2011-01-28 |
2023-08-12 |
Not clear |
Tsan-Ju Chen, Hsiu-Min Cheng, Dean-Chuan Wang, Hui-Shan Hun. Nonlethal aluminum maltolate can reduce brain-derived neurotrophic factor-induced Arc expression through interrupting the ERK signaling in SH-SY5Y neuroblastoma cells. Toxicology letters. vol 200. issue 1-2. 2011-01-18. PMID:21040763. |
in particular, activity-regulated cytoskeleton-associated protein (arc) has a versatile role in synaptic plasticity, and its synthesis can be induced by brain-derived neurotrophic factor (bdnf). |
2011-01-18 |
2023-08-12 |
human |
Silvia Alboni, Cristina Benatti, Giacomo Capone, Daniela Corsini, Federica Caggia, Fabio Tascedda, Julien Mendlewicz, Nicoletta Brunell. Time-dependent effects of escitalopram on brain derived neurotrophic factor (BDNF) and neuroplasticity related targets in the central nervous system of rats. European journal of pharmacology. vol 643. issue 2-3. 2010-12-28. PMID:20599917. |
escitalopram, known to be already effective in preclinical models of depression after 7 days, allowed us to investigate whether two effective treatment regimens (7 and 21 days) may contribute to synaptic plasticity by acting on bdnf signalling. |
2010-12-28 |
2023-08-12 |
rat |
Silvia Alboni, Cristina Benatti, Giacomo Capone, Daniela Corsini, Federica Caggia, Fabio Tascedda, Julien Mendlewicz, Nicoletta Brunell. Time-dependent effects of escitalopram on brain derived neurotrophic factor (BDNF) and neuroplasticity related targets in the central nervous system of rats. European journal of pharmacology. vol 643. issue 2-3. 2010-12-28. PMID:20599917. |
we focused our attention on two regulators of bdnf transcription, creb and carf (calcium responsive factor), and on kinases, camkii, erk1/2 and p38 mapk, linked to bdnf that play a distinctive role in synaptic plasticity. |
2010-12-28 |
2023-08-12 |
rat |
A Terracciano, B Martin, D Ansari, T Tanaka, L Ferrucci, S Maudsley, M P Mattson, P T Cost. Plasma BDNF concentration, Val66Met genetic variant and depression-related personality traits. Genes, brain, and behavior. vol 9. issue 5. 2010-11-15. PMID:20345896. |
brain-derived neurotrophic factor (bdnf) regulates synaptic plasticity and neurogenesis, and bdnf plasma and serum levels have been associated with depression, alzheimer's disease, and other psychiatric and neurodegenerative disorders. |
2010-11-15 |
2023-08-12 |
Not clear |
Shu-Chen Li, Christian Chicherio, Lars Nyberg, Timo von Oertzen, Irene E Nagel, Goran Papenberg, Thomas Sander, Hauke R Heekeren, Ulman Lindenberger, Lars Bäckma. Ebbinghaus revisited: influences of the BDNF Val66Met polymorphism on backward serial recall are modulated by human aging. Journal of cognitive neuroscience. vol 22. issue 10. 2010-09-22. PMID:19925205. |
the brain-derived neurotrophic factor (bdnf) plays an important role in activity-dependent synaptic plasticity, which underlies learning and memory. |
2010-09-22 |
2023-08-12 |
human |
Jun Gao, Wen-Yuan Wang, Ying-Wei Mao, Johannes Gräff, Ji-Song Guan, Ling Pan, Gloria Mak, Dohoon Kim, Susan C Su, Li-Huei Tsa. A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature. vol 466. issue 7310. 2010-09-13. PMID:20622856. |
sirt1 normally functions to limit expression of mir-134 via a repressor complex containing the transcription factor yy1, and unchecked mir-134 expression following sirt1 deficiency results in the downregulated expression of creb and brain-derived neurotrophic factor (bdnf), thereby impairing synaptic plasticity. |
2010-09-13 |
2023-08-12 |
Not clear |
Marie-Christine Pardo. Role of neurotrophic factors in behavioral processes: implications for the treatment of psychiatric and neurodegenerative disorders. Vitamins and hormones. vol 82. 2010-08-20. PMID:20472139. |
brain-derived neurotrophic factor (bdnf) has been the most widely studied neurotrophin because of its important role as modulator of synaptic plasticity, which is essential to the regulation of experience-dependent behavior. |
2010-08-20 |
2023-08-12 |
Not clear |