| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carla Cunha, Riccardo Brambilla, Kerrie L Thoma. A simple role for BDNF in learning and memory? Frontiers in molecular neuroscience. vol 3. 2011-07-14. PMID:20162032. |
more recently, bdnf has also emerged as an important regulator of synaptogenesis and synaptic plasticity mechanisms underlying learning and memory in the adult cns. |
2011-07-14 |
2023-08-12 |
human |
| Carla Cunha, Riccardo Brambilla, Kerrie L Thoma. A simple role for BDNF in learning and memory? Frontiers in molecular neuroscience. vol 3. 2011-07-14. PMID:20162032. |
in this review we will discuss our knowledge about the multiple intracellular signalling pathways activated by bdnf, and the role of this neurotrophin in long-term synaptic plasticity and memory formation as well as in synaptogenesis. |
2011-07-14 |
2023-08-12 |
human |
| Carla Cunha, Riccardo Brambilla, Kerrie L Thoma. A simple role for BDNF in learning and memory? Frontiers in molecular neuroscience. vol 3. 2011-07-14. PMID:20162032. |
we will show that maturation of bdnf, its cellular localization and its ability to regulate both excitatory and inhibitory synapses in the cns may result in conflicting alterations in synaptic plasticity and memory formation. |
2011-07-14 |
2023-08-12 |
human |
| Tadahiro Numakawa, Daisaku Yokomaku, Misty Richards, Hiroaki Hori, Naoki Adachi, Hiroshi Kunug. Functional interactions between steroid hormones and neurotrophin BDNF. World journal of biological chemistry. vol 1. issue 5. 2011-07-14. PMID:21540998. |
brain-derived neurotrophic factor (bdnf), a critical neurotrophin, regulates many neuronal aspects including cell differentiation, cell survival, neurotransmission, and synaptic plasticity in the central nervous system (cns). |
2011-07-14 |
2023-08-12 |
Not clear |
| H A Boger, P Mannangatti, D J Samuvel, A J Saylor, T S Bender, J F McGinty, A M Fortress, V Zaman, P Huang, L D Middaugh, P K Randall, L D Jayanthi, B Rohrer, K L Helke, A-C Granholm, S Ramamoorth. Effects of brain-derived neurotrophic factor on dopaminergic function and motor behavior during aging. Genes, brain, and behavior. vol 10. issue 2. 2011-06-15. PMID:20860702. |
brain-derived neurotrophic factor (bdnf) is critical in synaptic plasticity and in the survival and function of midbrain dopamine neurons. |
2011-06-15 |
2023-08-12 |
mouse |
| Giuseppe P Cortese, Ruth M Barrientos, Steven F Maier, Susan L Patterso. Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411668. |
interestingly, these deficits occur in forms of long-term memory and synaptic plasticity known to be strongly dependent on brain-derived neurotrophic factor (bdnf). |
2011-06-15 |
2023-08-12 |
rat |
| Giuseppe P Cortese, Ruth M Barrientos, Steven F Maier, Susan L Patterso. Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411668. |
these data suggest that inflammation-evoked reductions in bdnf at synapses might contribute to inflammation-evoked disruptions in long-term memory and synaptic plasticity in aging. |
2011-06-15 |
2023-08-12 |
rat |
| Chiara Cazzin, Silvia Mion, Fabrizio Caldara, Joseph M Rimland, Enrico Domenic. Microarray analysis of cultured rat hippocampal neurons treated with brain derived neurotrophic factor. Molecular biology reports. vol 38. issue 2. 2011-05-26. PMID:20535563. |
more studies are needed to investigate and confirm the role of these genes in synaptic plasticity, but the results reported in this paper show that microarray analysis of hippocampal cultures can be used to expand our current knowledge of the molecular events triggered by bdnf in the hippocampus. |
2011-05-26 |
2023-08-12 |
rat |
| Hui-li Liu, Gang Zhao, Kui Cai, Hai-hua Zhao, Li-de Sh. Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation. Behavioural brain research. vol 218. issue 2. 2011-05-06. PMID:21192984. |
however, bdnf has emerged as a crucial regulator of synaptic plasticity mechanisms underlying learning and memory in wild-type mice, but not in app/ps1 mice. |
2011-05-06 |
2023-08-12 |
mouse |
| Yogesh Dwived. Brain-derived neurotrophic factor: role in depression and suicide. Neuropsychiatric disease and treatment. vol 5. 2011-04-26. PMID:19721723. |
brain-derived neurotrophic factor (bdnf), one of the major neurotrophic factors, plays an important role in the maintenance and survival of neurons and in synaptic plasticity. |
2011-04-26 |
2023-08-12 |
Not clear |
| Hui Yu, Zhe-yu Che. The role of BDNF in depression on the basis of its location in the neural circuitry. Acta pharmacologica Sinica. vol 32. issue 1. 2011-04-25. PMID:21131999. |
brain-derived neurotrophic factor (bdnf) is broadly expressed in the developing and adult mammalian brain and has been implicated in development, neural regeneration, synaptic transmission, synaptic plasticity and neurogenesis. |
2011-04-25 |
2023-08-12 |
Not clear |
| Yen-Ching Wu, Rebecca Williamson, Zhi Li, Annalisa Vicario, Jerry Xu, Masataka Kasai, Yijuang Chern, Enrico Tongiorgi, Jay M Baraba. Dendritic trafficking of brain-derived neurotrophic factor mRNA: regulation by translin-dependent and -independent mechanisms. Journal of neurochemistry. vol 116. issue 6. 2011-04-15. PMID:21198640. |
dendritic trafficking and translation of brain-derived neurotrophic factor (bdnf) transcripts play a key role in mediating synaptic plasticity. |
2011-04-15 |
2023-08-12 |
mouse |
| Tatiana Adasme, Paola Haeger, Andrea C Paula-Lima, Italo Espinoza, M Mercedes Casas-Alarcón, M Angélica Carrasco, Cecilia Hidalg. Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 7. 2011-04-14. PMID:21282625. |
along with calcium signals, brain-derived neurotrophic factor (bdnf) is a key signaling molecule for hippocampal synaptic plasticity and spatial memory. |
2011-04-14 |
2023-08-12 |
rat |
| Antonio Lucio Teixeira, Izabela Guimarães Barbosa, Breno Satler Diniz, Arthur Kumme. Circulating levels of brain-derived neurotrophic factor: correlation with mood, cognition and motor function. Biomarkers in medicine. vol 4. issue 6. 2011-04-11. PMID:21133708. |
brain-derived neurotrophic factor (bdnf) is the most widely distributed neurotrophin in the cns, where it plays several pivotal roles in synaptic plasticity and neuronal survival. |
2011-04-11 |
2023-08-12 |
Not clear |
| Diana V Castillo, Martha L Escoba. A role for MAPK and PI-3K signaling pathways in brain-derived neurotrophic factor modification of conditioned taste aversion retention. Behavioural brain research. vol 217. issue 1. 2011-04-01. PMID:20974194. |
brain-derived neurotrophic factor (bdnf) has emerged as an important molecular mediator of synaptic plasticity. |
2011-04-01 |
2023-08-12 |
rat |
| Neslihan Aygun Kocabas, Irina Antonijevic, Carole Faghel, Carlos Forray, Siegfried Kasper, Yves Lecrubier, Sylvie Linotte, Isabelle Massat, Julien Mendlewicz, Magali Noro, Stuart Montgomery, Pierre Oswald, Lenore Snyder, Joseph Zohar, Daniel Souer. Brain-derived neurotrophic factor gene polymorphisms: influence on treatment response phenotypes of major depressive disorder. International clinical psychopharmacology. vol 26. issue 1. 2011-03-18. PMID:21188787. |
brain-derived neurotrophic factor (bdnf), a member of the nerve growth factor family of neurotrophins, has pivotal roles in neuronal survival, proliferation, and synaptic plasticity in the brain. |
2011-03-18 |
2023-08-12 |
Not clear |
| Ana Rita Santos, Diogo Comprido, Carlos B Duart. Regulation of local translation at the synapse by BDNF. Progress in neurobiology. vol 92. issue 4. 2011-03-15. PMID:20713125. |
the neurotrophin brain-derived neurotrophic factor (bdnf) plays a key role in synaptic plasticity, in part due to changes in local protein synthesis. |
2011-03-15 |
2023-08-12 |
Not clear |
| Ana Rita Santos, Diogo Comprido, Carlos B Duart. Regulation of local translation at the synapse by BDNF. Progress in neurobiology. vol 92. issue 4. 2011-03-15. PMID:20713125. |
this review highlights the recent advances in the understanding of the diversity of mechanisms that contribute to the regulation of the synaptic proteome by bdnf, which may account for its role in synaptic plasticity. |
2011-03-15 |
2023-08-12 |
Not clear |
| Patricia F Kao, David A Davis, Meredith G Banigan, Charles R Vanderburg, Sudha Seshadri, Ivana Delall. Modulators of cytoskeletal reorganization in CA1 hippocampal neurons show increased expression in patients at mid-stage Alzheimer's disease. PloS one. vol 5. issue 10. 2011-03-07. PMID:20967212. |
moreover, the increased expression of capzb2 mrna in ca1 pyramidal neurons in ad bb iii-iv is accompanied by an increased mrna expression of brain derived neurotrophic factor (bdnf) receptor tyrosine kinase b (trkb), mediator of synaptic plasticity in hippocampal neurons. |
2011-03-07 |
2023-08-12 |
Not clear |
| Andrea Antal, Leila Chaieb, Vera Moliadze, Katia Monte-Silva, Csaba Poreisz, Nivethida Thirugnanasambandam, Michael A Nitsche, Moneef Shoukier, Harald Ludwig, Walter Paulu. Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans. Brain stimulation. vol 3. issue 4. 2011-03-04. PMID:20965453. |
the brain-derived neurotrophic factor (bdnf) gene is involved in mechanisms of synaptic plasticity in the adult brain. |
2011-03-04 |
2023-08-12 |
human |