Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Midori Ninomiya, Tadahiro Numakawa, Naoki Adachi, Miyako Furuta, Shuichi Chiba, Misty Richards, Shigenobu Shibata, Hiroshi Kunug. Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20398734. |
brain-derived neurotrophic factor (bdnf), which plays a role in neuronal survival and synaptic plasticity in the central nervous system (cns), may also be associated with schizophrenia. |
2010-07-30 |
2023-08-12 |
rat |
Ipe Ninan, Kevin G Bath, Karishma Dagar, Rosalia Perez-Castro, Mark R Plummer, Francis S Lee, Moses V Cha. The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592208. |
the bdnf val66met polymorphism impairs nmda receptor-dependent synaptic plasticity in the hippocampus. |
2010-07-22 |
2023-08-12 |
mouse |
Ipe Ninan, Kevin G Bath, Karishma Dagar, Rosalia Perez-Castro, Mark R Plummer, Francis S Lee, Moses V Cha. The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592208. |
consistent with the nmda receptor-dependent synaptic plasticity impairment, we observed a significant decrease in nmda receptor neurotransmission in the ca1 pyramidal neurons of bdnf(met/met) mice. |
2010-07-22 |
2023-08-12 |
mouse |
Ipe Ninan, Kevin G Bath, Karishma Dagar, Rosalia Perez-Castro, Mark R Plummer, Francis S Lee, Moses V Cha. The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592208. |
thus, these results show that the bdnf val66met polymorphism has a direct effect on nmda receptor transmission, which may account for changes in synaptic plasticity in the hippocampus. |
2010-07-22 |
2023-08-12 |
mouse |
Dao-Yao He, Jérémie Neasta, Dorit Ro. Epigenetic regulation of BDNF expression via the scaffolding protein RACK1. The Journal of biological chemistry. vol 285. issue 25. 2010-07-21. PMID:20410295. |
furthermore, this novel mechanism for the regulation of exon-specific expression of the bdnf gene by rack1 could have implications on the neuronal functions of the growth factor including synaptic plasticity, learning, and memory. |
2010-07-21 |
2023-08-12 |
Not clear |
Fei Wang, Xin Geng, Hua-Ying Tao, Yan Chen. The restoration after repetitive transcranial magnetic stimulation treatment on cognitive ability of vascular dementia rats and its impacts on synaptic plasticity in hippocampal CA1 area. Journal of molecular neuroscience : MN. vol 41. issue 1. 2010-07-12. PMID:19953343. |
rtms plays an important and beneficial role in the restoration treatment of vascular dementia, which may be related to the mechanism that rtms can increase the mrna and protein expressions of bdnf, nmdar1, and syn and affect the synaptic plasticity in hippocampal ca1 area. |
2010-07-12 |
2023-08-12 |
rat |
Veronica Ghiglieri, Carmelo Sgobio, Stefano Patassini, Vincenza Bagetta, Anna Fejtova, Carmela Giampà, Silvia Marinucci, Alexandra Heyden, Eckart D Gundelfinger, Francesca R Fusco, Paolo Calabresi, Barbara Piccon. TrkB/BDNF-dependent striatal plasticity and behavior in a genetic model of epilepsy: modulation by valproic acid. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 7. 2010-07-09. PMID:20200504. |
brain-derived neurotrophic factor (bdnf) is a key factor for the induction and maintenance of synaptic plasticity and it is also implicated in the mechanisms underlying epilepsy-induced adaptive changes. |
2010-07-09 |
2023-08-12 |
mouse |
Lisete Haas, Luis V C Portela, Ana Elisa Böhmer, Jean Pierre Oses, Diogo R Lar. Increased plasma levels of brain derived neurotrophic factor (BDNF) in patients with fibromyalgia. Neurochemical research. vol 35. issue 5. 2010-07-08. PMID:20119637. |
brain-derived neurotrophic factor (bdnf) is involved in neuronal survival and synaptic plasticity of the central and peripheral nervous system. |
2010-07-08 |
2023-08-12 |
human |
S Fanous, R P Hammer, E M Nikulin. Short- and long-term effects of intermittent social defeat stress on brain-derived neurotrophic factor expression in mesocorticolimbic brain regions. Neuroscience. vol 167. issue 3. 2010-06-29. PMID:20206238. |
a potential candidate for mediating these effects is brain-derived neurotrophic factor (bdnf), a neurotrophin involved in synaptic plasticity and displaying alterations in dopaminergic regions in response to various types of stress. |
2010-06-29 |
2023-08-12 |
rat |
Tina B Lonsdorf, Almut I Weike, Armita Golkar, Martin Schalling, Alfons O Hamm, Arne Öhma. Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism. Behavioral neuroscience. vol 124. issue 1. 2010-06-28. PMID:20141276. |
we suggest that the bdnf met-allele may have a protective effect for the development of affective pathologies that may be mediated via reduced synaptic plasticity induced by negative experience. |
2010-06-28 |
2023-08-12 |
human |
John Kealy, Sean Commin. Frequency-dependent changes in synaptic plasticity and brain-derived neurotrophic factor (BDNF) expression in the CA1 to perirhinal cortex projection. Brain research. vol 1326. 2010-06-25. PMID:20193668. |
frequency-dependent changes in synaptic plasticity and brain-derived neurotrophic factor (bdnf) expression in the ca1 to perirhinal cortex projection. |
2010-06-25 |
2023-08-12 |
Not clear |
John Kealy, Sean Commin. Frequency-dependent changes in synaptic plasticity and brain-derived neurotrophic factor (BDNF) expression in the CA1 to perirhinal cortex projection. Brain research. vol 1326. 2010-06-25. PMID:20193668. |
here we investigate whether the ca1 to perirhinal projection in vivo in the anaesthetised animal shows a frequency-dependent pattern of synaptic plasticity that is coupled with brain-derived neurotrophic factor (bdnf) expression. |
2010-06-25 |
2023-08-12 |
Not clear |
John Kealy, Sean Commin. Frequency-dependent changes in synaptic plasticity and brain-derived neurotrophic factor (BDNF) expression in the CA1 to perirhinal cortex projection. Brain research. vol 1326. 2010-06-25. PMID:20193668. |
these findings suggest that the ca1 to perirhinal cortex projection is electrophysiologically excitatory in nature and that changes in bdnf levels in this projection may not be predictive of changes in synaptic plasticity. |
2010-06-25 |
2023-08-12 |
Not clear |
Susana Cohen-Cory, Adhanet H Kidane, Nicole J Shirkey, Sonya Marsha. Brain-derived neurotrophic factor and the development of structural neuronal connectivity. Developmental neurobiology. vol 70. issue 5. 2010-06-23. PMID:20186709. |
among the neurotrophins, brain-derived neurotrophic factor (bdnf) is highly conserved in gene structure and function during vertebrate evolution, and serves an important role during brain development and in synaptic plasticity. |
2010-06-23 |
2023-08-12 |
Not clear |
Antonio Terracciano, Toshiko Tanaka, Angelina R Sutin, Barbara Deiana, Lenuta Balaci, Serena Sanna, Nazario Olla, Andrea Maschio, Manuela Uda, Luigi Ferrucci, David Schlessinger, Paul T Cost. BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 5. 2010-06-21. PMID:20042999. |
brain-derived neurotrophic factor (bdnf) regulates synaptic plasticity and neurotransmission, and has been linked to neuroticism, a major risk factor for psychiatric disorders. |
2010-06-21 |
2023-08-12 |
Not clear |
Jamie Peters, Laura M Dieppa-Perea, Loyda M Melendez, Gregory J Quir. Induction of fear extinction with hippocampal-infralimbic BDNF. Science (New York, N.Y.). vol 328. issue 5983. 2010-06-16. PMID:20522777. |
brain-derived neurotrophic factor (bdnf) is a key mediator of synaptic plasticity in multiple brain areas. |
2010-06-16 |
2023-08-12 |
rat |
Kiriana K Cowansage, Joseph E LeDoux, Marie-H Monfil. Brain-derived neurotrophic factor: a dynamic gatekeeper of neural plasticity. Current molecular pharmacology. vol 3. issue 1. 2010-06-15. PMID:20030625. |
brain derived neurotrophic factor (bdnf), a member of the neurotrophin family of structurally related proteins that promote neuronal differentiation and survival during development, is a potent modulator of synaptic plasticity. |
2010-06-15 |
2023-08-12 |
Not clear |
Brita Fritsch, Janine Reis, Keri Martinowich, Heidi M Schambra, Yuanyuan Ji, Leonardo G Cohen, Bai L. Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning. Neuron. vol 66. issue 2. 2010-05-25. PMID:20434997. |
we propose that tdcs may improve motor skill learning through augmentation of synaptic plasticity that requires bdnf secretion and trkb activation within m1. |
2010-05-25 |
2023-08-12 |
mouse |
Sung-Wuk Jang, Xia Liu, Manuel Yepes, Kennie R Shepherd, Gary W Miller, Yang Liu, W David Wilson, Ge Xiao, Bruno Blanchi, Yi E Sun, Keqiang Y. A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 6. 2010-05-07. PMID:20133810. |
brain-derived neurotrophic factor (bdnf), a cognate ligand for the tyrosine kinase receptor b (trkb) receptor, mediates neuronal survival, differentiation, synaptic plasticity, and neurogenesis. |
2010-05-07 |
2023-08-12 |
mouse |
Shan-Jing Geng, Fei-Fei Liao, Wen-Hao Dang, Xu Ding, Xiao-Dan Liu, Jie Cai, Ji-Sheng Han, You Wan, Guo-Gang Xin. Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation. Experimental neurology. vol 222. issue 2. 2010-03-26. PMID:20079352. |
the nmda receptor and the brain-derived neurotrophic factor (bdnf) are involved in central sensitization and synaptic plasticity in the spinal cord. |
2010-03-26 |
2023-08-12 |
rat |