| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicola Kuczewski, Christophe Porcher, Nadine Ferrand, Hervé Fiorentino, Christophe Pellegrino, Richard Kolarow, Volkmar Lessmann, Igor Medina, Jean-Luc Gaiars. Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 27. 2008-08-12. PMID:18596175. |
therefore, together, our results support the hypothesis that bdnf might act as a target-derived messenger of activity-dependent synaptic plasticity and development. |
2008-08-12 |
2023-08-12 |
Not clear |
| Nitsan Kozlovsky, Zeev Kaplan, Joseph Zohar, Michael A Matar, Hady Shimon, Hagit Cohe. Protein synthesis inhibition before or after stress exposure results in divergent endocrine and BDNF responses disassociated from behavioral responses. Depression and anxiety. vol 25. issue 5. 2008-08-07. PMID:17828750. |
although the behavioral responses were similar when anisomycin was microinjected before or after stress exposure, the levels of mrnas for bdnf and trkb, which play a role in modulation of synaptic plasticity and the consolidation process, showed varying responses. |
2008-08-07 |
2023-08-12 |
rat |
| Bai Lu, Keri Martinowic. Cell biology of BDNF and its relevance to schizophrenia. Novartis Foundation symposium. vol 289. 2008-08-07. PMID:18497099. |
bdnf is a key regulator of synaptic plasticity and hence is thought to be uniquely important for various cognitive functions. |
2008-08-07 |
2023-08-12 |
Not clear |
| Bai Lu, Keri Martinowic. Cell biology of BDNF and its relevance to schizophrenia. Novartis Foundation symposium. vol 289. 2008-08-07. PMID:18497099. |
extending these studies to synaptic plasticity in other areas of the brain may help us to better understand how altered bdnf signalling could contribute to intermediate phenotypes associated with schizophrenia. |
2008-08-07 |
2023-08-12 |
Not clear |
| A Berry, A Greco, M Giorgio, P G Pelicci, R de Kloet, E Alleva, L Minghetti, F Cirull. Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice. Experimental gerontology. vol 43. issue 3. 2008-08-01. PMID:18065182. |
levels of brain-derived neurotrophic factor (bdnf), a neurotrophin involved in several aspects of synaptic plasticity, emotionality and pain sensitivity, were assessed in selected brain areas. |
2008-08-01 |
2023-08-12 |
mouse |
| Takahiro Nakajima, Moritoshi Sato, Naoko Akaza, Yoshio Umezaw. Cell-based fluorescent indicator to visualize brain-derived neurotrophic factor secreted from living neurons. ACS chemical biology. vol 3. issue 6. 2008-07-29. PMID:18510313. |
although there is mounting evidence that bdnf regulates neuronal development and synaptic plasticity, bdnf secretion has remained unclear due to lack of appropriate methods for the analysis of its dynamics. |
2008-07-29 |
2023-08-12 |
Not clear |
| Juan Ji An, Kusumika Gharami, Guey-Ying Liao, Newton H Woo, Anthony G Lau, Filip Vanevski, Enrique R Torre, Kevin R Jones, Yue Feng, Bai Lu, Baoji X. Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell. vol 134. issue 1. 2008-07-25. PMID:18614020. |
distinct role of long 3' utr bdnf mrna in spine morphology and synaptic plasticity in hippocampal neurons. |
2008-07-25 |
2023-08-12 |
mouse |
| B M Fontinha, M J Diógenes, J A Ribeiro, A M Sebastiã. Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18384819. |
since extracellular adenosine accumulates upon high-frequency neuronal firing, the present results reveal a key process to allow the influence of bdnf upon synaptic plasticity. |
2008-07-22 |
2023-08-12 |
Not clear |
| M J Thomas, P W Kalivas, Y Shaha. Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. British journal of pharmacology. vol 154. issue 2. 2008-06-19. PMID:18345022. |
these include the extracellular signal-regulated kinase (erk) signalling pathway, brain-derived neurotrophic factor (bdnf), glutamate transmission, and synaptic plasticity (primarily in the form of long-term potentiation and depression, ltp and ltd). |
2008-06-19 |
2023-08-12 |
Not clear |
| Pedro Bekinschtein, Martin Cammarota, Ivan Izquierdo, Jorge H Medin. BDNF and memory formation and storage. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 14. issue 2. 2008-06-12. PMID:17911219. |
during the past decade, a large body of evidence has implicated bdnf in synaptic plasticity. |
2008-06-12 |
2023-08-12 |
Not clear |
| Liron Abuhatzira, Kirill Makedonski, Yotam Kaufman, Aharon Razin, Ruth Sheme. MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production. Epigenetics. vol 2. issue 4. 2008-06-10. PMID:18075316. |
disruptions in the expression of the bdnf gene that encodes a neurotrophic factor involved in neuronal survival, differentiation and synaptic plasticity has been proposed to contribute to the molecular pathogenesis of rett syndrome. |
2008-06-10 |
2023-08-12 |
mouse |
| A L Carvalho, M V Caldeira, S D Santos, C B Duart. Role of the brain-derived neurotrophic factor at glutamatergic synapses. British journal of pharmacology. vol 153 Suppl 1. 2008-04-28. PMID:18059328. |
several evidences show impaired synaptic plasticity of glutamatergic synapses in diseases where compromised bdnf function has been observed, such as huntington's disease, depression, anxiety, and the bdnf polymorphism val66met, suggesting that upregulating bdnf-activated pathways may be therapeutically relevant. |
2008-04-28 |
2023-08-12 |
Not clear |
| A L Carvalho, M V Caldeira, S D Santos, C B Duart. Role of the brain-derived neurotrophic factor at glutamatergic synapses. British journal of pharmacology. vol 153 Suppl 1. 2008-04-28. PMID:18059328. |
this review focuses on recent advances in the understanding of the regulation of the glutamatergic synapse by bdnf, and its implications in synaptic plasticity. |
2008-04-28 |
2023-08-12 |
Not clear |
| Valentine Echeverria, Diego E Berman, Ottavio Aranci. Oligomers of beta-amyloid peptide inhibit BDNF-induced arc expression in cultured cortical Neurons. Current Alzheimer research. vol 4. issue 5. 2008-03-21. PMID:18220514. |
using a model of synaptic plasticity in which bdnf increases arc expression in cultured cortical neurons, we have found that an oligomeric form of abeta strongly inhibits the bdnf-induced increase of arc expression. |
2008-03-21 |
2023-08-12 |
mouse |
| Devin K Binde. Neurotrophins in the dentate gyrus. Progress in brain research. vol 163. 2008-03-14. PMID:17765730. |
bdnf in particular has important roles in neural development and cell survival, as well as appearing essential to molecular mechanisms of synaptic plasticity and larger scale structural rearrangements of axons and dendrites. |
2008-03-14 |
2023-08-12 |
Not clear |
| Devin K Binde. Neurotrophins in the dentate gyrus. Progress in brain research. vol 163. 2008-03-14. PMID:17765730. |
pathologic levels of bdnf-dependent synaptic plasticity may contribute to conditions such as epilepsy and chronic pain sensitization, whereas application of the trophic properties of bdnf may lead to novel therapeutic options in neurodegenerative diseases and perhaps even in neuropsychiatric disorders. |
2008-03-14 |
2023-08-12 |
Not clear |
| K Schindowski, K Belarbi, L Bué. Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes, brain, and behavior. vol 7 Suppl 1. 2008-03-12. PMID:18184369. |
in particular, brain-derived neurotrophic factor (bdnf) plays a crucial role in cognition, learning and memory formation by modulating synaptic plasticity and is, therefore, a critical molecule in dementia and neurodegenerative diseases. |
2008-03-12 |
2023-08-12 |
Not clear |
| Ke Ren, Ronald Dubne. Pain facilitation and activity-dependent plasticity in pain modulatory circuitry: role of BDNF-TrkB signaling and NMDA receptors. Molecular neurobiology. vol 35. issue 3. 2008-03-04. PMID:17917111. |
it is not surprising that a well-established regulator of synaptic plasticity, brain-derived neurotrophic factor (bdnf), contributes to the mechanisms of descending pain facilitation. |
2008-03-04 |
2023-08-12 |
Not clear |
| Xueying Jiang, Feng Tian, Yang Du, Neal G Copeland, Nancy A Jenkins, Lino Tessarollo, Xuan Wu, Hongna Pan, Xian-Zhang Hu, Ke Xu, Heather Kenney, Sean E Egan, Helen Turley, Adrian L Harris, Ann M Marini, Robert H Lipsk. BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 5. 2008-02-19. PMID:18234890. |
brain-derived neurotrophic factor (bdnf), via activation of trkb receptors, mediates vital physiological functions in the brain, ranging from neuronal survival to synaptic plasticity, and has been implicated in the pathophysiology of neurodegenerative disorders. |
2008-02-19 |
2023-08-12 |
mouse |
| Keri Martinowich, Bai L. Interaction between BDNF and serotonin: role in mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 1. 2008-02-14. PMID:17882234. |
brain-derived neurotrophic factor (bdnf) and serotonin (5-hydroxytryptamine, 5-ht) are two seemingly distinct signaling systems that play regulatory roles in many neuronal functions including survival, neurogenesis, and synaptic plasticity. |
2008-02-14 |
2023-08-12 |
Not clear |