| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joshua D Ohrtman, Elizabeth K Stancik, David M Lovinger, Margaret I Davi. Ethanol inhibits brain-derived neurotrophic factor stimulation of extracellular signal-regulated/mitogen-activated protein kinase in cerebellar granule cells. Alcohol (Fayetteville, N.Y.). vol 39. issue 1. 2006-10-06. PMID:16938627. |
brain-derived neurotrophic factor (bdnf) has emerged as a prominent mediator of neuronal development and synaptic plasticity. |
2006-10-06 |
2023-08-12 |
Not clear |
| William J Tyler, Xiao-lei Zhang, Kenichi Hartman, Jochen Winterer, Wolfgang Muller, Patric K Stanton, Lucas Pozzo-Mille. BDNF increases release probability and the size of a rapidly recycling vesicle pool within rat hippocampal excitatory synapses. The Journal of physiology. vol 574. issue Pt 3. 2006-09-26. PMID:16709633. |
since the endogenous bdnf scavenger trkb-igg prevented the enhancement of fm1-43 destaining rate caused by induction of long-term potentiation in acute hippocampal slices, the modulation of a rapidly recycling vesicle pool may underlie the role of bdnf in hippocampal long-term synaptic plasticity. |
2006-09-26 |
2023-08-12 |
rat |
| Kevin G Bath, Francis S Le. Variant BDNF (Val66Met) impact on brain structure and function. Cognitive, affective & behavioral neuroscience. vol 6. issue 1. 2006-09-19. PMID:16869232. |
in adults, bdnf is important in regulating synaptic plasticity and connectivity in the brain. |
2006-09-19 |
2023-08-12 |
human |
| J Soulé, E Messaoudi, C R Bramha. Brain-derived neurotrophic factor and control of synaptic consolidation in the adult brain. Biochemical Society transactions. vol 34. issue Pt 4. 2006-09-14. PMID:16856871. |
localization of bdnf and its receptor tyrosine kinase trkb (tropomyosin receptor kinase b) to glutamate synapses makes this system attractive as a dynamic, activity-dependent regulator of excitatory transmission and synaptic plasticity in the adult brain. |
2006-09-14 |
2023-08-12 |
rat |
| Subhash C Pandey, Huaibo Zhang, Adip Roy, Kaushik Misr. Central and medial amygdaloid brain-derived neurotrophic factor signaling plays a critical role in alcohol-drinking and anxiety-like behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 32. 2006-09-05. PMID:16899727. |
brain-derived neurotrophic factor (bdnf) is a member of the nerve growth factor family of neurotrophins and plays a vital role in synaptic plasticity. |
2006-09-05 |
2023-08-12 |
rat |
| Shelley J Allen, David Dawbar. Clinical relevance of the neurotrophins and their receptors. Clinical science (London, England : 1979). vol 110. issue 2. 2006-06-28. PMID:16411894. |
in addition, the role of bdnf (brain-derived neurotrophic factor) in synaptic plasticity and memory formation is discussed. |
2006-06-28 |
2023-08-12 |
Not clear |
| Sachiko Chikahisa, Hiroyoshi Sei, Masaki Morishima, Atsuko Sano, Kazuyoshi Kitaoka, Yutaka Nakaya, Yusuke Morit. Exposure to music in the perinatal period enhances learning performance and alters BDNF/TrkB signaling in mice as adults. Behavioural brain research. vol 169. issue 2. 2006-06-08. PMID:16530277. |
we examined the effect of music exposure during the perinatal period on learning behavior in adult mice, and measured the levels of brain-derived neurotrophic factor (bdnf) and its receptor, tyrosine kinase receptor b (trkb), which play critical roles in synaptic plasticity. |
2006-06-08 |
2023-08-12 |
mouse |
| Oleg V Dolotov, Ekaterina A Karpenko, Tamara S Seredenina, Lyudmila S Inozemtseva, Natalia G Levitskaya, Yuriy A Zolotarev, Andrey A Kamensky, Igor A Grivennikov, Juergen Engele, Nikolay F Myasoedo. Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain. Journal of neurochemistry. vol 97 Suppl 1. 2006-05-23. PMID:16635254. |
a clue to the molecular mechanism underlying this neurotropic action was recently given by the observation that semax stimulates the synthesis of brain-derived neurotrophic factor (bdnf), a potent modulator of synaptic plasticity, in astrocytes cultured from rat basal forebrain. |
2006-05-23 |
2023-08-12 |
rat |
| Dean-Chuan Wang, Shun-Sheng Chen, Yi-Ching Lee, Tsan-Ju Che. Amyloid-beta at sublethal level impairs BDNF-induced arc expression in cortical neurons. Neuroscience letters. vol 398. issue 1-2. 2006-05-10. PMID:16412575. |
consistent with the literature, arc, an indicator of synaptic plasticity, was induced by bdnf (25 ng/ml) in both dose- and time-dependent manners. |
2006-05-10 |
2023-08-12 |
rat |
| Tomoya Matsumoto, Tadahiro Numakawa, Daisaku Yokomaku, Naoki Adachi, Satoru Yamagishi, Yumiko Numakawa, Hiroshi Kunugi, Takahisa Taguch. Brain-derived neurotrophic factor-induced potentiation of glutamate and GABA release: different dependency on signaling pathways and neuronal activity. Molecular and cellular neurosciences. vol 31. issue 1. 2006-05-08. PMID:16214365. |
in conclusion, bdnf potentiates the excitatory and inhibitory system separately, which may be important for the regulation of synaptic plasticity. |
2006-05-08 |
2023-08-12 |
Not clear |
| Diana V Castillo, Yazmín Figueroa-Guzmán, Martha L Escoba. Brain-derived neurotrophic factor enhances conditioned taste aversion retention. Brain research. vol 1067. issue 1. 2006-05-02. PMID:16364259. |
brain-derived neurotrophic factor (bdnf) has recently emerged as one of the most potent molecular mediators of not only central synaptic plasticity, but also behavioral interactions between an organism and its environment. |
2006-05-02 |
2023-08-12 |
rat |
| Diana V Castillo, Yazmín Figueroa-Guzmán, Martha L Escoba. Brain-derived neurotrophic factor enhances conditioned taste aversion retention. Brain research. vol 1067. issue 1. 2006-05-02. PMID:16364259. |
these findings support the concept that bdnf may contribute to memory-related functions performed by a neocortical area, playing a critical role in long-term synaptic plasticity. |
2006-05-02 |
2023-08-12 |
rat |
| Robert H Ring, Janet Alder, Myles Fennell, Evguenia Kouranova, Ira B Black, Smita Thakker-Vari. Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth. Journal of neurobiology. vol 66. issue 4. 2006-04-28. PMID:16408296. |
we previously found that bdnf treatment acutely increases transcription of the synaptic vesicle protein rab3a, required for trophin-induced synaptic plasticity, as well as the peptide vgf, which increases during learning. |
2006-04-28 |
2023-08-12 |
Not clear |
| Robert H Ring, Janet Alder, Myles Fennell, Evguenia Kouranova, Ira B Black, Smita Thakker-Vari. Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth. Journal of neurobiology. vol 66. issue 4. 2006-04-28. PMID:16408296. |
consistent with the modulation of synaptic plasticity, bdnf treatment (3-6 h) induced mrnas encoding the synapse-associated proteins synaptojanin 2, neuronal pentraxin 1, septin 9, and ryanodine receptor 2. |
2006-04-28 |
2023-08-12 |
Not clear |
| Aiguo Wu, Zhe Ying, Fernando Gomez-Pinill. Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition. Experimental neurology. vol 197. issue 2. 2006-04-03. PMID:16364299. |
the analysis was focused on the bdnf system based on its action on synaptic plasticity and cognition by modulating synapsin i and creb. |
2006-04-03 |
2023-08-12 |
rat |
| Aiguo Wu, Zhe Ying, Fernando Gomez-Pinill. Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition. Experimental neurology. vol 197. issue 2. 2006-04-03. PMID:16364299. |
these results are in agreement with previous evidence, showing that oxidative stress can affect the injured brain by acting through the bdnf system to affect synaptic plasticity and cognition. |
2006-04-03 |
2023-08-12 |
rat |
| Wei Guo, Meredith T Robbins, Feng Wei, Shiping Zou, Ronald Dubner, Ke Re. Supraspinal brain-derived neurotrophic factor signaling: a novel mechanism for descending pain facilitation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 1. 2006-03-31. PMID:16399679. |
in the adult mammalian brain, brain-derived neurotrophic factor (bdnf) is critically involved in long-term synaptic plasticity. |
2006-03-31 |
2023-08-12 |
Not clear |
| Nobuyuki Shiina, Kazumi Shinkura, Makio Tokunag. A novel RNA-binding protein in neuronal RNA granules: regulatory machinery for local translation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 17. 2006-03-09. PMID:15858068. |
dissociation of rng105 from the rna granules is induced by bdnf, a growth factor responsible for synaptic plasticity. |
2006-03-09 |
2023-08-12 |
Not clear |
| Zachary C Baquet, Paula C Bickford, Kevin R Jone. Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 26. 2006-02-14. PMID:15987955. |
brain-derived neurotrophic factor (bdnf) has been implicated in regulating neuronal survival, differentiation, and synaptic plasticity. |
2006-02-14 |
2023-08-12 |
mouse |
| Bryan W Luikart, Serge Nef, Tuhin Virmani, Mark E Lush, Yajuan Liu, Ege T Kavalali, Luis F Parad. TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 15. 2006-02-13. PMID:15829629. |
to gain additional insight into the mechanism of bdnf and trkb influence on synapse formation and synaptic plasticity, we generated a conditional knock-out for trkb using the cre/loxp system. |
2006-02-13 |
2023-08-12 |
mouse |