| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew Lanktree, Alessio Squassina, Marilee Krinsky, John Strauss, Umesh Jain, Fabio Macciardi, James L Kennedy, Pierandrea Mugli. Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18286632. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin expressed in the brain throughout life and is involved in survival, differentiation, and synaptic plasticity of several neuronal systems including dopaminergic pathways. |
2008-12-04 |
2023-08-12 |
Not clear |
| Enrico Tongiorg. Activity-dependent expression of brain-derived neurotrophic factor in dendrites: facts and open questions. Neuroscience research. vol 61. issue 4. 2008-11-26. PMID:18550187. |
this review will highlight current knowledge on the mechanisms of spatial and temporal regulation of activity-dependent bdnf mrna localization in dendrites in relation with synaptic plasticity. |
2008-11-26 |
2023-08-12 |
Not clear |
| Matteo Bergami, Spartaco Santi, Elena Formaggio, Cinzia Cagnoli, Claudia Verderio, Robert Blum, Benedikt Berninger, Michela Matteoli, Marco Canoss. Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes. The Journal of cell biology. vol 183. issue 2. 2008-11-13. PMID:18852301. |
activity-dependent secretion of brain-derived neurotrophic factor (bdnf) is thought to enhance synaptic plasticity, but the mechanisms controlling extracellular availability and clearance of secreted bdnf are poorly understood. |
2008-11-13 |
2023-08-12 |
Not clear |
| Fatma Simsek-Duran, György Lonar. The role of RIM1alpha in BDNF-enhanced glutamate release. Neuropharmacology. vol 55. issue 1. 2008-11-05. PMID:18499195. |
the identity of molecular targets in bdnf's action on rab3a pathway, a synaptic vesicle protein involved in vesicle trafficking and synaptic plasticity, is not fully known. |
2008-11-05 |
2023-08-12 |
mouse |
| Joshua J Park, Niamh X Cawley, Y Peng Lo. A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons. Molecular and cellular neurosciences. vol 39. issue 1. 2008-10-29. PMID:18573344. |
anterograde transport of brain-derived neurotrophic factor (bdnf) vesicles from the soma to neurite terminals is necessary for activity-dependent secretion of bdnf to mediate synaptic plasticity, memory and learning, and retrograde bdnf transport back to the soma for recycling. |
2008-10-29 |
2023-08-12 |
Not clear |
| Alexi Nott, P Marc Watson, James D Robinson, Luca Crepaldi, Antonella Ricci. S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons. Nature. vol 455. issue 7211. 2008-10-21. PMID:18754010. |
brain-derived neurotrophic factor (bdnf) and other neurotrophins have a vital role in the development of the rat and mouse nervous system by influencing the expression of many specific genes that promote differentiation, cell survival, synapse formation and, later, synaptic plasticity. |
2008-10-21 |
2023-08-12 |
mouse |
| Laszlo Vutskits, Christopher Lysakowski, Christoph Czarnetzki, Benoit Jenny, Jean-Christophe Copin, Martin R Tramè. Plasma concentrations of brain-derived neurotrophic factor in patients undergoing minor surgery: a randomized controlled trial. Neurochemical research. vol 33. issue 7. 2008-08-20. PMID:18270817. |
we measured perioperative plasma concentrations of brain-derived neurotrophic factor (bdnf), a major mediator of synaptic plasticity in the central nervous system, in males, 30-65 years old, undergoing lumbar or cervical discotomy. |
2008-08-20 |
2023-08-12 |
Not clear |
| Nicola Kuczewski, Christophe Porcher, Nadine Ferrand, Hervé Fiorentino, Christophe Pellegrino, Richard Kolarow, Volkmar Lessmann, Igor Medina, Jean-Luc Gaiars. Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 27. 2008-08-12. PMID:18596175. |
therefore, together, our results support the hypothesis that bdnf might act as a target-derived messenger of activity-dependent synaptic plasticity and development. |
2008-08-12 |
2023-08-12 |
Not clear |
| Nitsan Kozlovsky, Zeev Kaplan, Joseph Zohar, Michael A Matar, Hady Shimon, Hagit Cohe. Protein synthesis inhibition before or after stress exposure results in divergent endocrine and BDNF responses disassociated from behavioral responses. Depression and anxiety. vol 25. issue 5. 2008-08-07. PMID:17828750. |
although the behavioral responses were similar when anisomycin was microinjected before or after stress exposure, the levels of mrnas for bdnf and trkb, which play a role in modulation of synaptic plasticity and the consolidation process, showed varying responses. |
2008-08-07 |
2023-08-12 |
rat |
| Bai Lu, Keri Martinowic. Cell biology of BDNF and its relevance to schizophrenia. Novartis Foundation symposium. vol 289. 2008-08-07. PMID:18497099. |
bdnf is a key regulator of synaptic plasticity and hence is thought to be uniquely important for various cognitive functions. |
2008-08-07 |
2023-08-12 |
Not clear |
| Bai Lu, Keri Martinowic. Cell biology of BDNF and its relevance to schizophrenia. Novartis Foundation symposium. vol 289. 2008-08-07. PMID:18497099. |
extending these studies to synaptic plasticity in other areas of the brain may help us to better understand how altered bdnf signalling could contribute to intermediate phenotypes associated with schizophrenia. |
2008-08-07 |
2023-08-12 |
Not clear |
| A Berry, A Greco, M Giorgio, P G Pelicci, R de Kloet, E Alleva, L Minghetti, F Cirull. Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice. Experimental gerontology. vol 43. issue 3. 2008-08-01. PMID:18065182. |
levels of brain-derived neurotrophic factor (bdnf), a neurotrophin involved in several aspects of synaptic plasticity, emotionality and pain sensitivity, were assessed in selected brain areas. |
2008-08-01 |
2023-08-12 |
mouse |
| Takahiro Nakajima, Moritoshi Sato, Naoko Akaza, Yoshio Umezaw. Cell-based fluorescent indicator to visualize brain-derived neurotrophic factor secreted from living neurons. ACS chemical biology. vol 3. issue 6. 2008-07-29. PMID:18510313. |
although there is mounting evidence that bdnf regulates neuronal development and synaptic plasticity, bdnf secretion has remained unclear due to lack of appropriate methods for the analysis of its dynamics. |
2008-07-29 |
2023-08-12 |
Not clear |
| Juan Ji An, Kusumika Gharami, Guey-Ying Liao, Newton H Woo, Anthony G Lau, Filip Vanevski, Enrique R Torre, Kevin R Jones, Yue Feng, Bai Lu, Baoji X. Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell. vol 134. issue 1. 2008-07-25. PMID:18614020. |
distinct role of long 3' utr bdnf mrna in spine morphology and synaptic plasticity in hippocampal neurons. |
2008-07-25 |
2023-08-12 |
mouse |
| B M Fontinha, M J Diógenes, J A Ribeiro, A M Sebastiã. Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18384819. |
since extracellular adenosine accumulates upon high-frequency neuronal firing, the present results reveal a key process to allow the influence of bdnf upon synaptic plasticity. |
2008-07-22 |
2023-08-12 |
Not clear |
| M J Thomas, P W Kalivas, Y Shaha. Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. British journal of pharmacology. vol 154. issue 2. 2008-06-19. PMID:18345022. |
these include the extracellular signal-regulated kinase (erk) signalling pathway, brain-derived neurotrophic factor (bdnf), glutamate transmission, and synaptic plasticity (primarily in the form of long-term potentiation and depression, ltp and ltd). |
2008-06-19 |
2023-08-12 |
Not clear |
| Pedro Bekinschtein, Martin Cammarota, Ivan Izquierdo, Jorge H Medin. BDNF and memory formation and storage. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 14. issue 2. 2008-06-12. PMID:17911219. |
during the past decade, a large body of evidence has implicated bdnf in synaptic plasticity. |
2008-06-12 |
2023-08-12 |
Not clear |
| Liron Abuhatzira, Kirill Makedonski, Yotam Kaufman, Aharon Razin, Ruth Sheme. MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production. Epigenetics. vol 2. issue 4. 2008-06-10. PMID:18075316. |
disruptions in the expression of the bdnf gene that encodes a neurotrophic factor involved in neuronal survival, differentiation and synaptic plasticity has been proposed to contribute to the molecular pathogenesis of rett syndrome. |
2008-06-10 |
2023-08-12 |
mouse |
| A L Carvalho, M V Caldeira, S D Santos, C B Duart. Role of the brain-derived neurotrophic factor at glutamatergic synapses. British journal of pharmacology. vol 153 Suppl 1. 2008-04-28. PMID:18059328. |
several evidences show impaired synaptic plasticity of glutamatergic synapses in diseases where compromised bdnf function has been observed, such as huntington's disease, depression, anxiety, and the bdnf polymorphism val66met, suggesting that upregulating bdnf-activated pathways may be therapeutically relevant. |
2008-04-28 |
2023-08-12 |
Not clear |
| A L Carvalho, M V Caldeira, S D Santos, C B Duart. Role of the brain-derived neurotrophic factor at glutamatergic synapses. British journal of pharmacology. vol 153 Suppl 1. 2008-04-28. PMID:18059328. |
this review focuses on recent advances in the understanding of the regulation of the glutamatergic synapse by bdnf, and its implications in synaptic plasticity. |
2008-04-28 |
2023-08-12 |
Not clear |