| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Civera, A Urios, M L Garcia-Torres, J Ortega, J Martinez-Valls, N Cassinello, J A del Olmo, A Ferrandez, J M Rodrigo, C Montoli. Relationship between insulin resistance, inflammation and liver cell apoptosis in patients with severe obesity. Diabetes/metabolism research and reviews. vol 26. issue 3. 2010-08-13. PMID:20222158. |
relationship between insulin resistance, inflammation and liver cell apoptosis in patients with severe obesity. |
2010-08-13 |
2023-08-12 |
Not clear |
| Russiachand Heikham, Ravi Shanka. Flanking region sequence information to refine microRNA target predictions. Journal of biosciences. vol 35. issue 1. 2010-08-05. PMID:20413915. |
we used our methodology over genes of three different pathways--toll-like receptor (tlr), apoptosis and insulin--to finally predict the most probable targets. |
2010-08-05 |
2023-08-12 |
Not clear |
| Guo Zhang, Xiaoping Li, Lili Zhang, Lijun Zhao, Jing Jiang, Jianliu Wang, Lihui We. The expression and role of hybrid insulin/insulin-like growth factor receptor type 1 in endometrial carcinoma cells. Cancer genetics and cytogenetics. vol 200. issue 2. 2010-07-30. PMID:20620597. |
the effect of inhibiting igf-i, igf-ii, and insulin on cell cycle progression and apoptosis was assessed by flow cytometry. |
2010-07-30 |
2023-08-12 |
Not clear |
| Guo Zhang, Xiaoping Li, Lili Zhang, Lijun Zhao, Jing Jiang, Jianliu Wang, Lihui We. The expression and role of hybrid insulin/insulin-like growth factor receptor type 1 in endometrial carcinoma cells. Cancer genetics and cytogenetics. vol 200. issue 2. 2010-07-30. PMID:20620597. |
both igfs and insulin significantly decreased apoptosis in hec-1a cells through hybrid-r, and a similar but moderate effect was observed in ishikawa cells. |
2010-07-30 |
2023-08-12 |
Not clear |
| Kimberly R Holloway, Tara N Calhoun, Madhurima Saxena, Cheynita F Metoyer, Ethan F Kandler, Chantal A Rivera, Kevin Pruit. SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 20. 2010-07-22. PMID:20439735. |
because sirt1 regulates very diverse responses such as apoptosis, insulin sensitivity, autophagy, differentiation, and stem cell pluripotency, it has been a challenge to reconcile how it orchestrates such pleiotropic effects. |
2010-07-22 |
2023-08-12 |
Not clear |
| Liping Wei, Dongdong Sun, Zhiyong Yin, Yuan Yuan, Andrew Hwang, Yingmei Zhang, Rui Si, Rongqing Zhang, Wenyi Guo, Feng Cao, Haichang Wan. A PKC-beta inhibitor protects against cardiac microvascular ischemia reperfusion injury in diabetic rats. Apoptosis : an international journal on programmed cell death. vol 15. issue 4. 2010-07-19. PMID:20044781. |
rbx and insulin administration significantly reduced the cardiac microvascular lesion region and apoptosis index of endothelial cells (all p < 0.05 vs. no-treatment group). |
2010-07-19 |
2023-08-12 |
rat |
| J-W Li, L-L Li, L-L Chang, Z-Y Wang, Y X. Stem cell factor protects against neuronal apoptosis by activating AKT/ERK in diabetic mice. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 42. issue 11. 2010-07-12. PMID:19802467. |
neuronal apoptosis occurs in the diabetic brain due to insulin deficiency or insulin resistance, both of which reduce the expression of stem cell factor (scf). |
2010-07-12 |
2023-08-12 |
mouse |
| J-W Li, L-L Li, L-L Chang, Z-Y Wang, Y X. Stem cell factor protects against neuronal apoptosis by activating AKT/ERK in diabetic mice. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 42. issue 11. 2010-07-12. PMID:19802467. |
in diabetic mice treated with insulin or scf, there was fewer structural change and apoptosis in the cortex compared to untreated mice. |
2010-07-12 |
2023-08-12 |
mouse |
| J-W Li, L-L Li, L-L Chang, Z-Y Wang, Y X. Stem cell factor protects against neuronal apoptosis by activating AKT/ERK in diabetic mice. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 42. issue 11. 2010-07-12. PMID:19802467. |
the apoptosis rate of the normal group, the diabetic group receiving vehicle, the diabetic group treated with insulin, and the diabetic group treated with scf was 0.54 +/- 0.077%, 2.83 +/- 0.156%, 1.86 +/- 0.094%, and 1.78 +/- 0.095% (mean +/- sem), respectively. |
2010-07-12 |
2023-08-12 |
mouse |
| Wissal El-Assaad, Erik Joly, Annie Barbeau, Robert Sladek, Jean Buteau, Isabel Maestre, Emilie Pepin, Shangang Zhao, José Iglesias, Enrique Roche, Marc Prentk. Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells. Endocrinology. vol 151. issue 7. 2010-07-05. PMID:20444946. |
however, the synergy between elevated glucose and palmitate to cause ss-cell toxicity in term of apoptosis and reduced glucose-induced insulin secretion only correlated with triglyceride and ceramide depositions. |
2010-07-05 |
2023-08-12 |
human |
| Zhengshan Zhao, Xu Zhang, Chunying Zhao, Jinwoo Choi, Jieyi Shi, Keying Song, John Turk, Zhongmin Alex M. Protection of pancreatic beta-cells by group VIA phospholipase A(2)-mediated repair of mitochondrial membrane peroxidation. Endocrinology. vol 151. issue 7. 2010-07-05. PMID:20463052. |
we show that islets isolated from ipla(2)beta(-/-) mice are more sensitive to staurosporine-induced apoptosis than those from wild-type littermates and that 2 wk of daily ip administration of staurosporine to ipla(2)beta(-/-) mice impairs both the animals' glucose tolerance and glucose-stimulated insulin secretion by their pancreatic islets. |
2010-07-05 |
2023-08-12 |
mouse |
| Peter Sogaard, Ferenc Szekeres, Pablo M Garcia-Roves, Dennis Larsson, Alexander V Chibalin, Juleen R Zierat. Spatial insulin signalling in isolated skeletal muscle preparations. Journal of cellular biochemistry. vol 109. issue 5. 2010-06-25. PMID:20069552. |
during in vitro incubation in the absence or presence of insulin, glycogen depletion occurs in the inner core of the muscle specimen, concomitant with increased staining of hypoxia-induced-factor-1-alpha and caspase-3, markers of hypoxia and apoptosis, respectively. |
2010-06-25 |
2023-08-12 |
mouse |
| Marie Courbebaisse, Jean-Claude Souberbielle, Dominique Prié, Eric Therve. [Non phosphocalcic actions of vitamin D]. Medecine sciences : M/S. vol 26. issue 4. 2010-06-24. PMID:20412748. |
calcitriol produced locally is considered to have autocrine and paracrine actions on cellular proliferation and differentiation, apoptosis, insulin and renin secretion, interleukin and bactericidal proteins production. |
2010-06-24 |
2023-08-12 |
Not clear |
| Pingping Li, Min Lu, M T Audrey Nguyen, Eun Ju Bae, Justin Chapman, Daorong Feng, Meredith Hawkins, Jeffrey E Pessin, Dorothy D Sears, Anh-Khoi Nguyen, Arezou Amidi, Steven M Watkins, UyenThao Nguyen, Jerrold M Olefsk. Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice. The Journal of biological chemistry. vol 285. issue 20. 2010-06-14. PMID:20308074. |
together, these results indicate that 1) cd11c-positive m1-like atms can exhibit phenotypic plasticity and that the polarization of these cells between inflammatory and non-inflammatory states is well correlated to the presence of absence of insulin resistance, and 2) adipocyte necrosis and apoptosis can be dissociated from atm accumulation. |
2010-06-14 |
2023-08-12 |
mouse |
| Wei-Jie Zhang, Xiao Luo, Zhan-Yun Gu. In vitro degradation of insulin-like peptide 3 by insulin-degrading enzyme. The protein journal. vol 29. issue 2. 2010-06-09. PMID:20082125. |
insulin-like peptide 3 (insl3) is an insulin superfamily peptide hormone, primarily expressed in the testes and playing a key role in the fetus testes descent and suppression of male germ cell apoptosis. |
2010-06-09 |
2023-08-12 |
human |
| Bai-feng Li, Yong-feng Liu, Ying Cheng, Jia-lin Zhang, Ben-gang Wan. [The effect of iNOS gene expression inhibited by RNA inference on the pancreas islet apoptosis and function in rats]. Zhonghua wai ke za zhi [Chinese journal of surgery]. vol 47. issue 18. 2010-06-03. PMID:20092778. |
to investigate the effect of inos gene on cell apoptosis and insulin secretion of pancreas islet in rats by rna inference (rnai). |
2010-06-03 |
2023-08-12 |
rat |
| Julie Kerr-Conte, Brigitte Vandewalle, Ericka Moerman, Bruno Lukowiak, Valery Gmyr, Laurent Arnalsteen, Robert Caiazzo, Adrien Sterkers, Thomas Hubert, Marie Christine Vantyghem, François Patto. Upgrading pretransplant human islet culture technology requires human serum combined with media renewal. Transplantation. vol 89. issue 9. 2010-05-28. PMID:20098354. |
at days 1 and 5 of culture, in vitro quality controls included islet viability, insulin content and function, apoptosis, and in vivo islet potency assay in nude mice. |
2010-05-28 |
2023-08-12 |
mouse |
| Donna H Wong, Jesus A Villanueva, Amanda B Cress, Antoni J Duleb. Effects of resveratrol on proliferation and apoptosis in rat ovarian theca-interstitial cells. Molecular human reproduction. vol 16. issue 4. 2010-05-27. PMID:20067985. |
rat t-i cells were cultured with and without resveratrol and/or insulin, and the effects on dna synthesis, number of viable cells and markers of apoptosis were evaluated. |
2010-05-27 |
2023-08-12 |
rat |
| Sebastian Rieck, Klaus H Kaestne. Expansion of beta-cell mass in response to pregnancy. Trends in endocrinology and metabolism: TEM. vol 21. issue 3. 2010-05-26. PMID:20015659. |
during times of prolonged metabolic demand for insulin, the endocrine pancreas can respond by increasing beta-cell mass, both by increasing cell size and by changing the balance between beta-cell proliferation and apoptosis. |
2010-05-26 |
2023-08-12 |
Not clear |
| Margherita Lasi, Charles N David, Angelika Böttge. Apoptosis in pre-Bilaterians: Hydra as a model. Apoptosis : an international journal on programmed cell death. vol 15. issue 3. 2010-05-25. PMID:20041301. |
regulation of apoptosis in hydra may involve bh-3 only proteins and survival pathways, possibly including insulin signalling. |
2010-05-25 |
2023-08-12 |
Not clear |