| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Jung, M Miura, J Yua. Suppression of interleukin-1 beta-converting enzyme-mediated cell death by insulin-like growth factor. The Journal of biological chemistry. vol 271. issue 9. 1996-06-11. PMID:8617790. |
ice-mediated apoptosis of cos cells in serum-free medium is suppressed by insulin-like growth factor (igf)-1 and insulin. |
1996-06-11 |
2023-08-12 |
Not clear |
| M Tanaka, M Sawada, S Yoshida, F Hanaoka, T Marunouch. Insulin prevents apoptosis of external granular layer neurons in rat cerebellar slice cultures. Neuroscience letters. vol 199. issue 1. 1996-03-19. PMID:8584221. |
insulin prevents apoptosis of external granular layer neurons in rat cerebellar slice cultures. |
1996-03-19 |
2023-08-12 |
rat |
| M Tanaka, M Sawada, S Yoshida, F Hanaoka, T Marunouch. Insulin prevents apoptosis of external granular layer neurons in rat cerebellar slice cultures. Neuroscience letters. vol 199. issue 1. 1996-03-19. PMID:8584221. |
insulin deprivation induced apoptosis of granule neurons largely in the external granular layer, but scarcely in the internal granular layer. |
1996-03-19 |
2023-08-12 |
rat |
| M Tanaka, M Sawada, S Yoshida, F Hanaoka, T Marunouch. Insulin prevents apoptosis of external granular layer neurons in rat cerebellar slice cultures. Neuroscience letters. vol 199. issue 1. 1996-03-19. PMID:8584221. |
these results suggest that insulin may prevent apoptosis of premigratory granule neurons during the development of the cerebellar cortex. |
1996-03-19 |
2023-08-12 |
rat |
| C Minshall, S Arkins, G G Freund, K W Kelle. Requirement for phosphatidylinositol 3'-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8558020. |
recently, phosphatidylinositol 3'-kinase (pi 3-kinase) has been shown to be integral in the pathway by which insulin and nerve growth factor prevent apoptosis. |
1996-02-27 |
2023-08-12 |
Not clear |
| A M Rampalli, P S Zelenk. Insulin regulates expression of c-fos and c-jun and suppresses apoptosis of lens epithelial cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 6. issue 8. 1996-02-20. PMID:8547223. |
insulin regulates expression of c-fos and c-jun and suppresses apoptosis of lens epithelial cells. |
1996-02-20 |
2023-08-12 |
chicken |
| A M Rampalli, P S Zelenk. Insulin regulates expression of c-fos and c-jun and suppresses apoptosis of lens epithelial cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 6. issue 8. 1996-02-20. PMID:8547223. |
in the absence of insulin, 6-day embryonic chicken lens epithelial explants undergo apoptosis as shown by changes in cell morphology, dna fragmentation, and loss of trypan blue exclusion. |
1996-02-20 |
2023-08-12 |
chicken |
| A M Rampalli, P S Zelenk. Insulin regulates expression of c-fos and c-jun and suppresses apoptosis of lens epithelial cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 6. issue 8. 1996-02-20. PMID:8547223. |
expression of these genes was also induced in the absence of insulin, but mrna levels remained elevated as the cells underwent apoptosis. |
1996-02-20 |
2023-08-12 |
chicken |
| A M Rampalli, P S Zelenk. Insulin regulates expression of c-fos and c-jun and suppresses apoptosis of lens epithelial cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 6. issue 8. 1996-02-20. PMID:8547223. |
since c-fos and c-jun have been shown to play a role in apoptosis in other cell types, the ability of insulin to regulate expression of these genes may be central to its ability to act as a survival factor for lens epithelial cells. |
1996-02-20 |
2023-08-12 |
chicken |
| H R Kim, S Upadhyay, G Li, K C Palmer, T F Deue. Platelet-derived growth factor induces apoptosis in growth-arrested murine fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 21. 1995-11-14. PMID:7568162. |
furthermore, we show that epidermal growth factor also induces apoptotic cell death in serum-deprived nrk cells, epidermal growth factor enhances the rate of apoptosis in pdgf-treated cells, and a progression factor (insulin) but not endogenously expressed bc1-2 fully protects nrk cells from pdgf-stimulated apoptosis. |
1995-11-14 |
2023-08-12 |
rat |
| A G Estévez, R Radi, L Barbeito, J T Shin, J A Thompson, J S Beckma. Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. Journal of neurochemistry. vol 65. issue 4. 1995-10-25. PMID:7561848. |
furthermore, pretreatment of cells with nerve growth factor or insulin, but not epidermal growth factor, was protective against peroxynitrite-induced apoptosis. |
1995-10-25 |
2023-08-12 |
Not clear |
| X Wu, Z Fan, H Masui, N Rosen, J Mendelsoh. Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. The Journal of clinical investigation. vol 95. issue 4. 1995-05-09. PMID:7706497. |
apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. |
1995-05-09 |
2023-08-12 |
human |
| X Wu, Z Fan, H Masui, N Rosen, J Mendelsoh. Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. The Journal of clinical investigation. vol 95. issue 4. 1995-05-09. PMID:7706497. |
addition of igf-1 or high concentrations of insulin can delay apoptosis induced by mab 225, while the g1 arrest cannot be reversed by either igf-1 or insulin. |
1995-05-09 |
2023-08-12 |
human |
| G R Merlo, F Basolo, L Fiore, L Duboc, N E Hyne. p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of EGF and insulin. The Journal of cell biology. vol 128. issue 6. 1995-04-24. PMID:7896881. |
p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of egf and insulin. |
1995-04-24 |
2023-08-12 |
Not clear |
| E Goodman, P Fiedor, S Fein, M Hardy, E Atha. Low-dose ultraviolet B pretreatment of human islets reduces graft immunogenicity through the induction of antigen-presenting cell apoptosis without adversely affecting insulin secretion. Transplantation proceedings. vol 27. issue 1. 1995-04-05. PMID:7533382. |
low-dose ultraviolet b pretreatment of human islets reduces graft immunogenicity through the induction of antigen-presenting cell apoptosis without adversely affecting insulin secretion. |
1995-04-05 |
2023-08-12 |
human |
| S Y Chun, H Billig, J L Tilly, I Furuta, A Tsafriri, A J Hsue. Gonadotropin suppression of apoptosis in cultured preovulatory follicles: mediatory role of endogenous insulin-like growth factor I. Endocrinology. vol 135. issue 5. 1994-12-16. PMID:7525255. |
like gonadotropins, treatment with igf-i and insulin also suppressed the spontaneous onset of apoptosis, with igf-i being more effective than insulin. |
1994-12-16 |
2023-08-12 |
human |
| A M Montgomery, R A Reisfeld, D A Cheres. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 19. 1994-10-14. PMID:7522323. |
apoptosis of alpha v(-) cells within this matrix could be overcome by the addition of insulin or serum. |
1994-10-14 |
2023-08-12 |
human |
| L Y Chuang, W C Hung, C C Chang, J H Tsa. Characterization of apoptosis induced by transforming growth factor beta 1 in human hepatoma cells. Anticancer research. vol 14. issue 1A. 1994-05-26. PMID:8166442. |
we found that tgf-beta 1-induced cell death is independent of cytosolic calcium and protein kinase c. insulin and tumor promotor can rescue hepatoma cells from apoptosis, but the effect is time-dependent. |
1994-05-26 |
2023-08-12 |
human |
| G Rodriguez-Tarduchy, M K Collins, I García, A López-Riva. Insulin-like growth factor-I inhibits apoptosis in IL-3-dependent hemopoietic cells. Journal of immunology (Baltimore, Md. : 1950). vol 149. issue 2. 1992-08-11. PMID:1624800. |
insulin at high concentration had a weak protective action and igf-ii was inactive in suppressing apoptosis in these il-3-dependent hemopoietic cells. |
1992-08-11 |
2023-08-11 |
Not clear |