| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Hague, T S Bracey, D J Hicks, J C Reed, C Paraskev. Decreased levels of p26-Bcl-2, but not p30 phosphorylated Bcl-2, precede TGFbeta1-induced apoptosis in colorectal adenoma cells. Carcinogenesis. vol 19. issue 9. 1998-10-22. PMID:9771943. |
tgfbeta does not induce apoptosis in rg/c2 cells even if hydrocortisone and insulin are removed from the culture medium. |
1998-10-22 |
2023-08-12 |
human |
| A Hague, T S Bracey, D J Hicks, J C Reed, C Paraskev. Decreased levels of p26-Bcl-2, but not p30 phosphorylated Bcl-2, precede TGFbeta1-induced apoptosis in colorectal adenoma cells. Carcinogenesis. vol 19. issue 9. 1998-10-22. PMID:9771943. |
in bh/c1 cells, tgfbeta induces apoptosis in the presence of insulin and hydrocortisone. |
1998-10-22 |
2023-08-12 |
human |
| J Saldeen, N Wels. Nicotinamide-induced apoptosis in insulin producing cells is associated with cleavage of poly(ADP-ribose) polymerase. Molecular and cellular endocrinology. vol 139. issue 1-2. 1998-10-15. PMID:9705078. |
nicotinamide-induced apoptosis in insulin producing cells is associated with cleavage of poly(adp-ribose) polymerase. |
1998-10-15 |
2023-08-12 |
rat |
| H Hikita, E F Nuwaysir, J Vaughan, K Babcock, M J Haas, Y P Dragan, H C Pito. The effect of short-term fasting, phenobarbital and refeeding on apoptotic loss, cell replication and gene expression in rat liver during the promotion stage. Carcinogenesis. vol 19. issue 8. 1998-09-24. PMID:9744538. |
both the decrease in insulin growth factor i and the elevation of c-myc expression during the fasting period may indicate the role of these genes in the transcriptional regulation of hepatocyte apoptosis in both normal and preneoplastic hepatocytes in the rat. |
1998-09-24 |
2023-08-12 |
rat |
| E J de la Rosa, E Vega-Núñez, A V Morales, J Serna, E Rubio, F de Pabl. Modulation of the chaperone heat shock cognate 70 by embryonic (pro)insulin correlates with prevention of apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 17. 1998-09-17. PMID:9707581. |
modulation of the chaperone heat shock cognate 70 by embryonic (pro)insulin correlates with prevention of apoptosis. |
1998-09-17 |
2023-08-12 |
chicken |
| E J de la Rosa, E Vega-Núñez, A V Morales, J Serna, E Rubio, F de Pabl. Modulation of the chaperone heat shock cognate 70 by embryonic (pro)insulin correlates with prevention of apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 17. 1998-09-17. PMID:9707581. |
insights have emerged concerning insulin function during development, from the finding that apoptosis during chicken embryo neurulation is prevented by prepancreatic (pro)insulin. |
1998-09-17 |
2023-08-12 |
chicken |
| E J de la Rosa, E Vega-Núñez, A V Morales, J Serna, E Rubio, F de Pabl. Modulation of the chaperone heat shock cognate 70 by embryonic (pro)insulin correlates with prevention of apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 17. 1998-09-17. PMID:9707581. |
these results argue in favor of hsc70 involvement, modulated by embryonic (pro)insulin, in the prevention of apoptosis during early development and suggest a role for a molecular chaperone in normal embryogenesis. |
1998-09-17 |
2023-08-12 |
chicken |
| K W Kelley, W A Meier, C Minshall, D H Schacher, Q Liu, R VanHoy, W Burgess, R Dantze. Insulin growth factor-I inhibits apoptosis in hematopoietic progenitor cells. Implications in thymic aging. Annals of the New York Academy of Sciences. vol 840. 1998-07-09. PMID:9629278. |
insulin growth factor-i inhibits apoptosis in hematopoietic progenitor cells. |
1998-07-09 |
2023-08-12 |
Not clear |
| J Downwar. Mechanisms and consequences of activation of protein kinase B/Akt. Current opinion in cell biology. vol 10. issue 2. 1998-06-18. PMID:9561851. |
activated pkb/akt provides a survival signal that protects cells from apoptosis induced by various stresses, and also mediates a number of metabolic effects of insulin. |
1998-06-18 |
2023-08-12 |
Not clear |
| D R Alessi, P Cohe. Mechanism of activation and function of protein kinase B. Current opinion in genetics & development. vol 8. issue 1. 1998-05-21. PMID:9529606. |
the past year has seen significant advances in our understanding of how protein kinase b (pkb) is activated and of the central role it plays in insulin signalling and in mediating the protective effects of survival factors against apoptosis. |
1998-05-21 |
2023-08-12 |
Not clear |
| Y P Zhou, D Teng, F Dralyuk, D Ostrega, M W Roe, L Philipson, K S Polonsk. Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. The Journal of clinical investigation. vol 101. issue 8. 1998-05-12. PMID:9541492. |
this study investigated the role of intracellular free ca2+ concentration ([ca2+]i) in apoptosis in min6 cells, an insulin secreting cell line, and in mouse islets. |
1998-05-12 |
2023-08-12 |
mouse |
| M Tanaka, M Sawada, M Miura, T Marunouch. Insulin-like growth factor-I analogue prevents apoptosis mediated through an interleukin-1 beta converting enzyme (caspase-1)-like protease of cerebellar external granular layer neurons: developmental stage-specific mechanisms of neuronal cell death. Neuroscience. vol 84. issue 1. 1998-05-08. PMID:9522365. |
insulin deprivation induced apoptosis of granule neurons in external granular layer but not in internal granular layer. |
1998-05-08 |
2023-08-12 |
rat |
| A Pick, J Clark, C Kubstrup, M Levisetti, W Pugh, S Bonner-Weir, K S Polonsk. Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. Diabetes. vol 47. issue 3. 1998-04-07. PMID:9519740. |
role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male zucker diabetic fatty rat. |
1998-04-07 |
2023-08-12 |
rat |
| N Mizuno, H Yoshitomi, H Ishida, H Kuromi, J Kawaki, Y Seino, S Sein. Altered bcl-2 and bax expression and intracellular Ca2+ signaling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion. Endocrinology. vol 139. issue 3. 1998-03-12. PMID:9492080. |
altered bcl-2 and bax expression and intracellular ca2+ signaling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion. |
1998-03-12 |
2023-08-12 |
Not clear |
| N Mizuno, H Yoshitomi, H Ishida, H Kuromi, J Kawaki, Y Seino, S Sein. Altered bcl-2 and bax expression and intracellular Ca2+ signaling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion. Endocrinology. vol 139. issue 3. 1998-03-12. PMID:9492080. |
min6 cells exhibit reduced insulin secretion induced by glucose regardless of the molecular pathway of apoptosis. |
1998-03-12 |
2023-08-12 |
Not clear |
| N Mizuno, H Yoshitomi, H Ishida, H Kuromi, J Kawaki, Y Seino, S Sein. Altered bcl-2 and bax expression and intracellular Ca2+ signaling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion. Endocrinology. vol 139. issue 3. 1998-03-12. PMID:9492080. |
apoptosis in pancreatic beta-cells, therefore, may be closely related to the impairment of insulin secretion in certain pathological conditions such as diabetes mellitus. |
1998-03-12 |
2023-08-12 |
Not clear |
| F Bertrand, A Atfi, A Cadoret, G L'Allemain, H Robin, O Lascols, J Capeau, G Cherqu. A role for nuclear factor kappaB in the antiapoptotic function of insulin. The Journal of biological chemistry. vol 273. issue 5. 1998-02-23. PMID:9446605. |
insulin (10(-9)-10(-7) m) inhibited apoptosis induced by serum withdrawal in cho-r cells in a concentration-dependent manner. |
1998-02-23 |
2023-08-12 |
Not clear |
| C Bozzo, G Bellomo, L Silengo, G Tarone, F Altrud. Soluble integrin ligands and growth factors independently rescue neuroblastoma cells from apoptosis under nonadherent conditions. Experimental cell research. vol 237. issue 2. 1998-02-03. PMID:9434628. |
in addition to integrin stimulation, serum, insulin, and nerve growth factor inhibited suspension-induced apoptosis of sk-n-be cells. |
1998-02-03 |
2023-08-12 |
human |
| J G Mabley, V Belin, N John, I C Gree. Insulin-like growth factor I reverses interleukin-1beta inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of Langerhans. FEBS letters. vol 417. issue 2. 1997-12-22. PMID:9395303. |
insulin-like growth factor i reverses interleukin-1beta inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of langerhans. |
1997-12-22 |
2023-08-12 |
rat |
| J G Mabley, V Belin, N John, I C Gree. Insulin-like growth factor I reverses interleukin-1beta inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of Langerhans. FEBS letters. vol 417. issue 2. 1997-12-22. PMID:9395303. |
we have previously observed that treatment of rat islets of langerhans with interleukin-1beta for 12 h results in nitric oxide-dependent inhibition of insulin secretion, while 48 h treatment increased rates of islet cell death by apoptosis. |
1997-12-22 |
2023-08-12 |
rat |