| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Matsuzawa, T Kawamura, S Mitsuhashi, T Suzuki, Y Matsuo, M Suzuki, Y Mizuno, K Kikuch. Thyrsiferyl 23-acetate and its derivatives induce apoptosis in various T- and B-leukemia cells. Bioorganic & medicinal chemistry. vol 7. issue 2. 1999-07-19. PMID:10218832. |
the tf-23a-induced apoptosis was prevented by fetal calf serum and insulin, but not by egf or pdgf. |
1999-07-19 |
2023-08-12 |
Not clear |
| V Hadjivassiliou, M H Green, R F James, S M Swift, H A Clayton, I C Gree. Insulin secretion, DNA damage, and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite, and cytokines. Nitric oxide : biology and chemistry. vol 2. issue 6. 1999-07-15. PMID:10342486. |
insulin secretion, dna damage, and apoptosis in human and rat islets of langerhans following exposure to nitric oxide, peroxynitrite, and cytokines. |
1999-07-15 |
2023-08-12 |
human |
| V Hadjivassiliou, M H Green, R F James, S M Swift, H A Clayton, I C Gree. Insulin secretion, DNA damage, and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite, and cytokines. Nitric oxide : biology and chemistry. vol 2. issue 6. 1999-07-15. PMID:10342486. |
insulin secretory response to glucose, insulin content, dna strand breakage, and early-to-late stage apoptosis were recorded in each experiment. |
1999-07-15 |
2023-08-12 |
human |
| M Prisco, G Romano, F Peruzzi, B Valentinis, R Baserg. Insulin and IGF-I receptors signaling in protection from apoptosis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 31. issue 2-3. 1999-06-22. PMID:10226786. |
insulin and igf-i receptors signaling in protection from apoptosis. |
1999-06-22 |
2023-08-12 |
mouse |
| N Farrelly, Y J Lee, J Oliver, C Dive, C H Streul. Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling. The Journal of cell biology. vol 144. issue 6. 1999-06-14. PMID:10087274. |
extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling. |
1999-06-14 |
2023-08-12 |
Not clear |
| N Farrelly, Y J Lee, J Oliver, C Dive, C H Streul. Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling. The Journal of cell biology. vol 144. issue 6. 1999-06-14. PMID:10087274. |
in addition, a hormonal signal from insulin or insulin-like growth factors, but not hydrocortisone or prolactin, is necessary to suppress mammary cell apoptosis, indicating that bm and soluble factors cooperate in survival signaling. |
1999-06-14 |
2023-08-12 |
Not clear |
| N Farrelly, Y J Lee, J Oliver, C Dive, C H Streul. Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling. The Journal of cell biology. vol 144. issue 6. 1999-06-14. PMID:10087274. |
since phosphatidylinositol 3-kinase was required for mammary epithelial cell survival, we propose that a possible mechanism for bm-mediated suppression of apoptosis is through its facilitative effects on insulin signaling. |
1999-06-14 |
2023-08-12 |
Not clear |
| H Bar-On, R Ben-Sasson, E Ziv, N Arar, E Shafri. Irreversibility of nutritionally induced NIDDM in Psammomys obesus is related to beta-cell apoptosis. Pancreas. vol 18. issue 3. 1999-06-11. PMID:10206484. |
we examined islet beta cells of psammomys in the four stages of progression to diabetes by staining for insulin as well as for apoptosis by the terminal deoxynucleotidyl transferase biotin-dutp nick end labeling (tunel) and visualizing the biotin-labeled cleavage sites. |
1999-06-11 |
2023-08-12 |
Not clear |
| G Dell'Antonio, P Rovere, F Mangili, A A Manfred. Heterogeneity and susceptibility to apoptosis of human renal carcinoma cells in vitro. European journal of histochemistry : EJH. vol 42. issue 4. 1999-06-10. PMID:10068906. |
long-term treatments with insulin or alpha-interferon, but not with the epithelial growth factor (egf), similarly differentiated bkr cells and abated their susceptibility to spontaneous and actinomycin-d induced apoptosis. |
1999-06-10 |
2023-08-12 |
human |
| J P Godbout, K A Cengel, S L Cheng, C Minshall, K W Kelley, G G Freun. Insulin activates caspase-3 by a phosphatidylinositol 3'-kinase-dependent pathway. Cellular signalling. vol 11. issue 1. 1999-05-28. PMID:10206340. |
cell death was doubled by insulin and was due to a 3-fold increase in apoptosis of cells in the g1/g0 phase of the cell cycle. |
1999-05-28 |
2023-08-12 |
Not clear |
| J P Godbout, K A Cengel, S L Cheng, C Minshall, K W Kelley, G G Freun. Insulin activates caspase-3 by a phosphatidylinositol 3'-kinase-dependent pathway. Cellular signalling. vol 11. issue 1. 1999-05-28. PMID:10206340. |
taken together, these findings indicate that insulin activates caspase-3 by a pi3-kinase-dependent pathway resulting in increased apoptosis and cell death. |
1999-05-28 |
2023-08-12 |
Not clear |
| B Díaz, B Pimentel, F de Pablo, E J de La Ros. Apoptotic cell death of proliferating neuroepithelial cells in the embryonic retina is prevented by insulin. The European journal of neuroscience. vol 11. issue 5. 1999-05-26. PMID:10215915. |
insulin, expressed in the early chick embryonic retina as proinsulin, attenuated apoptosis in growth factor-deprived organotypic culture of e5 retina. |
1999-05-26 |
2023-08-12 |
chicken |
| R Haviv, R Stei. Nerve growth factor inhibits apoptosis induced by tumor necrosis factor in PC12 cells. Journal of neuroscience research. vol 55. issue 3. 1999-05-25. PMID:10348657. |
the tnfalpha-induced apoptosis was inhibited by nerve growth factor (ngf) but not by insulin. |
1999-05-25 |
2023-08-12 |
Not clear |
| b' F J Gunn-Moore, J M Tavar\\xc3\\xa. Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or beta-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation. Neuroscience letters. vol 250. issue 1. 1999-05-19. PMID:9696064.' |
bdnf and insulin can prevent apoptosis induced by serum withdrawal or the addition of glutamate or beta-amyloid peptide. |
1999-05-19 |
2023-08-12 |
Not clear |
| K S Shindler, A M Yunker, R Cahn, J Zha, S J Korsmeyer, K A Rot. Trophic support promotes survival of bcl-x-deficient telencephalic cells in vitro. Cell death and differentiation. vol 5. issue 10. 1999-05-06. PMID:10203689. |
addition of trophic factors to basal medium revealed that insulin and insulin-like growth factors (igfs), but not other trophic factors, reduced apoptosis of wild-type and bcl-x-deficient telencephalic cells. |
1999-05-06 |
2023-08-12 |
Not clear |
| M Breidert, A Böttner, S Möller, L Herberg, S Bornstei. Apoptosis in the adrenal gland of non-obese diabetic (NOD) mice. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 106. issue 6. 1999-04-30. PMID:10079028. |
since the autoimmune process leading to the manifestation of insulin dependent diabetes mellitus (iddm) can also affect the sympathochromaffin system, we analyzed the role of apoptosis and infiltration of the adrenal medulla as features of this autoimmune process in parallel with the development of diabetes. |
1999-04-30 |
2023-08-12 |
mouse |
| C Alarcón, A V Morales, B Pimentel, J Serna, F de Pabl. (Pro)insulin and insulin-like growth factor I complementary expression and roles in early development. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 121. issue 1. 1999-03-08. PMID:9972280. |
(pro)insulin mrna is expressed in the chick embryo during neurulation and early organogenesis and its inhibition by antisense oligodeoxynucleotides increase apoptosis. |
1999-03-08 |
2023-08-12 |
mouse |
| C Alarcón, A V Morales, B Pimentel, J Serna, F de Pabl. (Pro)insulin and insulin-like growth factor I complementary expression and roles in early development. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 121. issue 1. 1999-03-08. PMID:9972280. |
modulation of apoptosis by (pro)insulin in retina may be largely responsible for the observed stimulation of dna synthesis and neuronal differentiation. |
1999-03-08 |
2023-08-12 |
mouse |
| S Emami, K Regnauld, N Ferrand, A Astesano, M Pessah, H Phan, C Boissard, J M Garel, G Rosseli. Stimulatory transducing systems in pancreatic islet cells. Annals of the New York Academy of Sciences. vol 865. 1999-02-16. PMID:9928004. |
the identification of numerous signaling molecule subtypes, together with the discovery of their specific subcellular distribution, will help the functional characterization of their intraregulatory pathways, leading to the extrusion of insulin or glucagon secretory granules, and those leading to differentiation and apoptosis of islet cells. |
1999-02-16 |
2023-08-12 |
Not clear |
| C Kuhn, S A Hurwitz, M G Kumar, J Cotton, D F Spanda. Activation of the insulin-like growth factor-1 receptor promotes the survival of human keratinocytes following ultraviolet B irradiation. International journal of cancer. vol 80. issue 3. 1999-02-11. PMID:9935186. |
we found that the only growth factor that provided protection from uvb-induced apoptosis was insulin and that the protective effect elicited by insulin was not due to binding the insulin receptor but, rather, to activation of the insulin-like growth factor-1 (igf-1) receptor. |
1999-02-11 |
2023-08-12 |
human |