| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Haviv, R Stei. Nerve growth factor inhibits apoptosis induced by tumor necrosis factor in PC12 cells. Journal of neuroscience research. vol 55. issue 3. 1999-05-25. PMID:10348657. |
the tnfalpha-induced apoptosis was inhibited by nerve growth factor (ngf) but not by insulin. |
1999-05-25 |
2023-08-12 |
Not clear |
| b' F J Gunn-Moore, J M Tavar\\xc3\\xa. Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or beta-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation. Neuroscience letters. vol 250. issue 1. 1999-05-19. PMID:9696064.' |
bdnf and insulin can prevent apoptosis induced by serum withdrawal or the addition of glutamate or beta-amyloid peptide. |
1999-05-19 |
2023-08-12 |
Not clear |
| K S Shindler, A M Yunker, R Cahn, J Zha, S J Korsmeyer, K A Rot. Trophic support promotes survival of bcl-x-deficient telencephalic cells in vitro. Cell death and differentiation. vol 5. issue 10. 1999-05-06. PMID:10203689. |
addition of trophic factors to basal medium revealed that insulin and insulin-like growth factors (igfs), but not other trophic factors, reduced apoptosis of wild-type and bcl-x-deficient telencephalic cells. |
1999-05-06 |
2023-08-12 |
Not clear |
| M Breidert, A Böttner, S Möller, L Herberg, S Bornstei. Apoptosis in the adrenal gland of non-obese diabetic (NOD) mice. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 106. issue 6. 1999-04-30. PMID:10079028. |
since the autoimmune process leading to the manifestation of insulin dependent diabetes mellitus (iddm) can also affect the sympathochromaffin system, we analyzed the role of apoptosis and infiltration of the adrenal medulla as features of this autoimmune process in parallel with the development of diabetes. |
1999-04-30 |
2023-08-12 |
mouse |
| C Alarcón, A V Morales, B Pimentel, J Serna, F de Pabl. (Pro)insulin and insulin-like growth factor I complementary expression and roles in early development. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 121. issue 1. 1999-03-08. PMID:9972280. |
(pro)insulin mrna is expressed in the chick embryo during neurulation and early organogenesis and its inhibition by antisense oligodeoxynucleotides increase apoptosis. |
1999-03-08 |
2023-08-12 |
mouse |
| C Alarcón, A V Morales, B Pimentel, J Serna, F de Pabl. (Pro)insulin and insulin-like growth factor I complementary expression and roles in early development. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 121. issue 1. 1999-03-08. PMID:9972280. |
modulation of apoptosis by (pro)insulin in retina may be largely responsible for the observed stimulation of dna synthesis and neuronal differentiation. |
1999-03-08 |
2023-08-12 |
mouse |
| S Emami, K Regnauld, N Ferrand, A Astesano, M Pessah, H Phan, C Boissard, J M Garel, G Rosseli. Stimulatory transducing systems in pancreatic islet cells. Annals of the New York Academy of Sciences. vol 865. 1999-02-16. PMID:9928004. |
the identification of numerous signaling molecule subtypes, together with the discovery of their specific subcellular distribution, will help the functional characterization of their intraregulatory pathways, leading to the extrusion of insulin or glucagon secretory granules, and those leading to differentiation and apoptosis of islet cells. |
1999-02-16 |
2023-08-12 |
Not clear |
| C Kuhn, S A Hurwitz, M G Kumar, J Cotton, D F Spanda. Activation of the insulin-like growth factor-1 receptor promotes the survival of human keratinocytes following ultraviolet B irradiation. International journal of cancer. vol 80. issue 3. 1999-02-11. PMID:9935186. |
we found that the only growth factor that provided protection from uvb-induced apoptosis was insulin and that the protective effect elicited by insulin was not due to binding the insulin receptor but, rather, to activation of the insulin-like growth factor-1 (igf-1) receptor. |
1999-02-11 |
2023-08-12 |
human |
| G Dawson, R Goswami, J Kilkus, D Wiesner, S Dawso. The formation of ceramide from sphingomyelin is associated with cellular apoptosis. Acta biochimica Polonica. vol 45. issue 2. 1999-01-20. PMID:9821861. |
apoptosis is also important in normal brain development and neuronal survival is dependent upon phosphatidylinositol 3-kinase (pi3-kinase) activation by growth factors (insulin, nerve growth factor etc.). |
1999-01-20 |
2023-08-12 |
Not clear |
| I D Román, N Rodríguez-Henche, J A Fueyo, J A Zueco, C Menor, J C Prieto, L G Guijarr. Cyclosporin A induces apoptosis in rat hepatocytes in culture. Archives of toxicology. vol 72. issue 9. 1999-01-07. PMID:9806427. |
cyclosporin a (csa) at concentrations up to 1 microm induced apoptosis in a dose-dependent manner in cultured rat hepatocytes for 48 h in the presence of insulin and epidermal growth factor (egf). |
1999-01-07 |
2023-08-12 |
rat |
| A Herrler, C A Krusche, H M Beie. Insulin and insulin-like growth factor-I promote rabbit blastocyst development and prevent apoptosis. Biology of reproduction. vol 59. issue 6. 1998-12-28. PMID:9828171. |
insulin and insulin-like growth factor-i promote rabbit blastocyst development and prevent apoptosis. |
1998-12-28 |
2023-08-12 |
rabbit |
| A Herrler, C A Krusche, H M Beie. Insulin and insulin-like growth factor-I promote rabbit blastocyst development and prevent apoptosis. Biology of reproduction. vol 59. issue 6. 1998-12-28. PMID:9828171. |
in contrast, coat-free embryos cultured without igf-i or insulin supplementation show apoptosis. |
1998-12-28 |
2023-08-12 |
rabbit |
| A Herrler, C A Krusche, H M Beie. Insulin and insulin-like growth factor-I promote rabbit blastocyst development and prevent apoptosis. Biology of reproduction. vol 59. issue 6. 1998-12-28. PMID:9828171. |
because igf-i stimulates cell proliferation and prevents apoptosis, we investigated whether insulin or igf-i may act as "survival factors" in preimplantation development. |
1998-12-28 |
2023-08-12 |
rabbit |
| A Herrler, C A Krusche, H M Beie. Insulin and insulin-like growth factor-I promote rabbit blastocyst development and prevent apoptosis. Biology of reproduction. vol 59. issue 6. 1998-12-28. PMID:9828171. |
by immunohistochemistry we could show that addition of insulin (0.68-68 nm) decreased apoptosis and increased cell proliferation in a dose-dependent manner, supporting blastocyst development significantly. |
1998-12-28 |
2023-08-12 |
rabbit |
| W Lee-Kwon, D Park, P V Baskar, S Kole, M Bernie. Antiapoptotic signaling by the insulin receptor in Chinese hamster ovary cells. Biochemistry. vol 37. issue 45. 1998-12-21. PMID:9843380. |
we have sought to determine whether insulin can promote cell survival and protect chinese hamster ovary (cho) cells from apoptosis induced by serum starvation. |
1998-12-21 |
2023-08-12 |
Not clear |
| W Lieberthal, V Triaca, J S Koh, P J Pagano, J S Levin. Role of superoxide in apoptosis induced by growth factor withdrawal. The American journal of physiology. vol 275. issue 5. 1998-12-10. PMID:9815127. |
both epidermal growth factor (egf) and high-dose insulin directly inhibit apoptosis of mpt cells deprived of growth factors. |
1998-12-10 |
2023-08-12 |
mouse |
| W Lieberthal, V Triaca, J S Koh, P J Pagano, J S Levin. Role of superoxide in apoptosis induced by growth factor withdrawal. The American journal of physiology. vol 275. issue 5. 1998-12-10. PMID:9815127. |
growth factor deprivation also results in activation of caspase activity, which is inhibited by egf and high-dose insulin as well as by the ros scavengers and antioxidants that inhibit apoptosis. |
1998-12-10 |
2023-08-12 |
mouse |
| S Janciauskiene, B Ahré. Different sensitivity to the cytotoxic action of IAPP fibrils in two insulin-producing cell lines, HIT-T15 and RINm5F cells. Biochemical and biophysical research communications. vol 251. issue 3. 1998-12-03. PMID:9791005. |
iapp fibrils (apoptosis (tunel assay), and glucose-stimulated insulin secretion and the cytosolic concentration of ca2+ were unaffected. |
1998-12-03 |
2023-08-12 |
Not clear |
| L Yenush, C Zanella, T Uchida, D Bernal, M F Whit. The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin. Molecular and cellular biology. vol 18. issue 11. 1998-11-23. PMID:9774692. |
the pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin. |
1998-11-23 |
2023-08-12 |
Not clear |
| L Yenush, C Zanella, T Uchida, D Bernal, M F Whit. The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin. Molecular and cellular biology. vol 18. issue 11. 1998-11-23. PMID:9774692. |
32d cells have few insulin receptors and no irs proteins; therefore, insulin failed to inhibit apoptosis during il-3 withdrawal. |
1998-11-23 |
2023-08-12 |
Not clear |