| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Danusa de Castro Damasio, Stefanie Nolte, Leonardo Puchetti Polak, Anna Paula Brandt, Natália Borges Bonan, Luciana Zischler, Patrícia M Stuelp-Campelo, Silvia Maria S C Cadena, Lúcia de Noronha, Selene L Elífio-Esposito, Andréa Novais Moreno-Amara. The lectin BJcuL induces apoptosis through TRAIL expression, caspase cascade activation and mitochondrial membrane permeability in a human colon adenocarcinoma cell line. Toxicon : official journal of the International Society on Toxinology. vol 90. 2015-06-25. PMID:25194746. |
it has been demonstrated that the cytotoxic effect of bjcul, the lectin isolated from bothrops jararacussu venom, on human gastric carcinoma is accompanied by the inhibition of extracellular matrix adhesion, cytoskeleton disassembly and apoptosis induction. |
2015-06-25 |
2023-08-13 |
human |
| L M Sosedova, M A Novikov, E A Titov, V S Rukavishniko. [Evaluation of biologic effects caused by nano-silver influence on brain tissue of experimental animals]. Meditsina truda i promyshlennaia ekologiia. issue 4. 2015-06-25. PMID:26065242. |
comparing results of structural study of nervous tissue with expression of proteins caspase-3 and bcl-2 proves ability of nanosilver incapsulated into polymer matrix to penetrate through blood-brain barrier and induce apoptosis in neurons of brain cortex. |
2015-06-25 |
2023-08-13 |
rat |
| Wei Chen, David P Cormode, Zahi A Fayad, Willem J M Mulde. Nanoparticles as magnetic resonance imaging contrast agents for vascular and cardiac diseases. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. vol 3. issue 2. 2015-06-23. PMID:20967875. |
nanoparticle probes detecting inflammation, apoptosis, extracellular matrix, and angiogenesis may provide tools for assessing the risk of progressive vascular dysfunction and heart failure. |
2015-06-23 |
2023-08-12 |
Not clear |
| Valérian Bunel, Marie-Hélène Antoine, Joëlle Nortier, Pierre Duez, Caroline Stévign. Protective effects of schizandrin and schizandrin B towards cisplatin nephrotoxicity in vitro. Journal of applied toxicology : JAT. vol 34. issue 12. 2015-06-22. PMID:24155209. |
results indicated that: (i) both schi and schi b enhanced cell survival via reducing apoptosis rate; (ii) only schi showed moderate effects towards modulation of regeneration capacities of healthy cells; (iii) both schi and schi b limited extracellular matrix deposition; and (iv) both compounds could help preventing dedifferentiation processes via the β-catenin pathway. |
2015-06-22 |
2023-08-12 |
Not clear |
| Gian Mario Tiboni, Adalisa Ponzan. Nitric oxide and teratogenesis: an update. Current pharmaceutical design. vol 20. issue 34. 2015-06-22. PMID:24502594. |
nitric oxide (no), generated by no synthase (nos) enzymes, is an important bioactive molecule involved in the regulation of several biological phenomena that are crucial for organogenesis, including gene expression, cell growth, matrix remolding, proliferation, differentiation and apoptosis. |
2015-06-22 |
2023-08-12 |
mouse |
| Bassem Allam, Emmanuelle Pales Espinosa, Arnaud Tanguy, Fanny Jeffroy, Cedric Le Bris, Christine Paillar. Transcriptional changes in Manila clam (Ruditapes philippinarum) in response to Brown Ring Disease. Fish & shellfish immunology. vol 41. issue 1. 2015-06-22. PMID:24882017. |
lectins, c1q domain-containing proteins) and killing (defensin), apoptosis regulation (death-associated protein, bcl-2) and in biomineralization (shell matrix proteins, perlucin, galaxin, chitin- and calcium-binding proteins). |
2015-06-22 |
2023-08-13 |
Not clear |
| Sravanth K Hindupur, Sai A Balaji, Meera Saxena, Shubham Pandey, Gopalkrishnashetty Sreenivasmurthy Sravan, Namrata Heda, M Vijaya Kumar, Geetashree Mukherjee, Devaveena Dey, Annapoorni Rangaraja. Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells. Breast cancer research : BCR. vol 16. issue 4. 2015-06-22. PMID:25096718. |
matrix detachment triggers anoikis, a form of apoptosis, in most normal epithelial cells, while acquisition of anoikis resistance is a prime requisite for solid tumor growth. |
2015-06-22 |
2023-08-13 |
human |
| Jianwei Xu, Eun Seong Lee, Seon Ha Baek, Shin-Young Ahn, Sejoong Kim, Ki Young Na, Dong-Wan Chae, Ho Jun Chi. Effect of bilirubin on triglyceride synthesis in streptozotocin-induced diabetic nephropathy. Journal of Korean medical science. vol 29 Suppl 2. 2015-06-16. PMID:25317020. |
bilirubin treatment also decreased the amount of mesangial matrix, lowered the expression of renal collagen iv and transforming growth factor (tgf)-β1, and reduced the level of apoptosis in the kidney, compared to the dm group. |
2015-06-16 |
2023-08-13 |
rat |
| Muhammad Fawwaz Abdullah, Siti Fadilah Abdullah, Nor Shamsuria Omar, Zuliani Mahmood, Siti Noor Fazliah Mohd Noor, Thirumulu Ponnuraj Kannan, Khairani Idah Mokhta. Proliferation rate of stem cells derived from human dental pulp and identification of differentially expressed genes. Cell biology international. vol 38. issue 5. 2015-06-15. PMID:24375868. |
timp1 is involved in degradation of the extracellular matrix, cell proliferation and anti-apoptotic function and rps8 is involved as a rate-limiting factor in translational regulation; col1a1 is involved in the resistance and elasticity of the tissues; fstl1 is an autoantigen associated with rheumatoid arthritis; lgals1 is involved in cell growth, differentiation, adhesion, rna processing, apoptosis and malignant transformation. |
2015-06-15 |
2023-08-12 |
human |
| Mumtaz V Rojiani, Sampa Ghoshal-Gupta, Ammar Kutiyanawalla, Sunil Mathur, Amyn M Rojian. TIMP-1 overexpression in lung carcinoma enhances tumor kinetics and angiogenesis in brain metastasis. Journal of neuropathology and experimental neurology. vol 74. issue 4. 2015-06-15. PMID:25756591. |
tissue inhibitors of matrix metalloproteinase (timp) orchestrate many biologic activities, including inhibition of matrix metalloproteinase activity, activation of pro-matrix metalloproteinases, and regulation of cell proliferation, angiogenesis, and apoptosis induction. |
2015-06-15 |
2023-08-13 |
mouse |
| Susan Chubinskaya, Markus A Wimme. Key Pathways to Prevent Posttraumatic Arthritis for Future Molecule-Based Therapy. Cartilage. vol 4. issue 3 Suppl. 2015-06-13. PMID:26069661. |
the vast majority of the literature pointed to chondrocyte death and apoptosis, inflammation and matrix damage/fragmentation being the earliest events that follow joint trauma. |
2015-06-13 |
2023-08-13 |
Not clear |
| Ariane Mallat, Jasper Lodder, Fatima Teixeira-Clerc, Richard Moreau, Patrice Codogno, Sophie Lotersztaj. Autophagy: a multifaceted partner in liver fibrosis. BioMed research international. vol 2014. 2015-06-11. PMID:25254217. |
fibrosis results from prolonged parenchymal cell apoptosis and necrosis associated with an inflammatory reaction that leads to recruitment of immune cells, activation and accumulation of fibrogenic cells, and extracellular matrix accumulation. |
2015-06-11 |
2023-08-13 |
Not clear |
| Raju R Rayavarapu, Brendan Heiden, Nicholas Pagani, Melissa M Shaw, Sydney Shuff, Siyuan Zhang, Zachary T Schafe. The role of multicellular aggregation in the survival of ErbB2-positive breast cancer cells during extracellular matrix detachment. The Journal of biological chemistry. vol 290. issue 14. 2015-06-09. PMID:25681438. |
in order for metastasis to occur, cancer cells need to evade anoikis, which is defined as apoptosis caused by loss of attachment to extracellular matrix (ecm). |
2015-06-09 |
2023-08-13 |
Not clear |
| Hui Wang, Wei Sun, Wen-Zhong Zhang, Chun-Yan Ge, Jing-Tao Zhang, Zhong-Yan Liu, Yue-Zu Fa. Inhibition of tumor vasculogenic mimicry and prolongation of host survival in highly aggressive gallbladder cancers by norcantharidin via blocking the ephrin type a receptor 2/focal adhesion kinase/paxillin signaling pathway. PloS one. vol 9. issue 5. 2015-06-08. PMID:24811250. |
the results showed that after treatment with nctd, gbc-sd cells were unable to form vm structures when injecting into nude mouse, growth of the xenograft was inhibited and these observations were confirmed by facts that vm formation by three-dimensional (3-d) matrix, proliferation, apoptosis, invasion, migration of gbc-sd cells were affected; and survival time of the xenograft mice was prolonged. |
2015-06-08 |
2023-08-13 |
mouse |
| Meng-yu Zhou, Wei-dong Ni. [Effect of Enterococcus faecalis on apoptosis rate and the release of matrix metalloproteinase-8 of polymorphonuclear leukocytes]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology. vol 27. issue 4. 2015-06-06. PMID:19769269. |
[effect of enterococcus faecalis on apoptosis rate and the release of matrix metalloproteinase-8 of polymorphonuclear leukocytes]. |
2015-06-06 |
2023-08-12 |
Not clear |
| Meng-yu Zhou, Wei-dong Ni. [Effect of Enterococcus faecalis on apoptosis rate and the release of matrix metalloproteinase-8 of polymorphonuclear leukocytes]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology. vol 27. issue 4. 2015-06-06. PMID:19769269. |
to evaluate the release of matrix metalloproteinase-8 (mmp-8) and apoptosis rate of polymorphonuclear leukocytes (pmns) after pmns was triggered by enterococcus faecalis (e. faecalis) in vitro. |
2015-06-06 |
2023-08-12 |
Not clear |
| Jin-Hao Miao, Shu-Qiang Wang, Ming-Hui Zhang, Feng-Bin Yu, Lei Zhang, Zhong-Xiang Yu, Yong Kuan. Knockdown of galectin-1 suppresses the growth and invasion of osteosarcoma cells through inhibition of the MAPK/ERK pathway. Oncology reports. vol 32. issue 4. 2015-06-01. PMID:25069486. |
knockdown of gal1 suppressed cell proliferative activities and invasive potential and induced apoptosis in os cells with decreased expression of p38mapk, p-erk, ki-67 and matrix metallopeptidase-9 (mmp-9) and increased expression of caspase-3. |
2015-06-01 |
2023-08-13 |
human |
| Xu-Hui Zhou, Chao-Qun Yang, Cheng-Lin Zhang, Yang Gao, Hong-Bin Yuan, Ce Wan. RASSF5 inhibits growth and invasion and induces apoptosis in osteosarcoma cells through activation of MST1/LATS1 signaling. Oncology reports. vol 32. issue 4. 2015-06-01. PMID:25109282. |
a gain-of-function approach was used to observe the effects of lentiviral vector-mediated overexpression of rassf5 (lv-rassf5) on cell growth, invasion and apoptosis, respectively, as indicated by mtt, transwell and flow cytometry assays, and the expression levels of mammalian sterile 20-like (mst1) kinase, large tumor suppressor 1 (lats1), proliferating cell nuclear antigen (pcna), matrix metallopeptidase-9 (mmp-9) and p53 were detected by real-time pcr and western blot assays in os cells (mg-63 and u-2 os). |
2015-06-01 |
2023-08-13 |
human |
| J Y Cha, M D Pereira, A A Smith, K S Houschyar, X Yin, S Mouraret, J B Brunski, J A Helm. Multiscale analyses of the bone-implant interface. Journal of dental research. vol 94. issue 3. 2015-05-29. PMID:25628271. |
at multiple time points, molecular, cellular, and histomorphometric analyses were performed to quantitatively determine the effect of high and low strains on apoptosis, mineralization, resorption, and collagen matrix deposition in peri-implant bone. |
2015-05-29 |
2023-08-13 |
Not clear |
| Nandor Gabor Than, Roberto Romero, Andrea Balogh, Eva Karpati, Salvatore Andrea Mastrolia, Orna Staretz-Chacham, Sinuhe Hahn, Offer Erez, Zoltan Papp, Chong Jai Ki. Galectins: Double-edged Swords in the Cross-roads of Pregnancy Complications and Female Reproductive Tract Inflammation and Neoplasia. Journal of pathology and translational medicine. vol 49. issue 3. 2015-05-28. PMID:26018511. |
they are pleiotropic regulators of key biological processes, such as cell growth, proliferation, differentiation, apoptosis, signal transduction, and pre-mrna splicing, as well as homo- and heterotypic cell-cell and cell-extracellular matrix interactions. |
2015-05-28 |
2023-08-13 |
Not clear |