| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Huang, Dakuan Gao, Xiaofan Jiang, Shijie Hu, Lei Zhang, Zhou Fe. Resveratrol inhibits oxygen-glucose deprivation-induced MMP-3 expression and cell apoptosis in primary cortical cells via the NF-κB pathway. Molecular medicine reports. vol 10. issue 2. 2015-02-12. PMID:24840287. |
the aim of the present study was to investigate whether res has neuroprotective effects in primary cortical neurons subjected to transient oxygen-glucose deprivation (ogd) via inhibiting the expression of the gene encoding stromelysin-1, also known as matrix metalloproteinase-3 (mmp-3), and via inhibiting cell apoptosis. |
2015-02-12 |
2023-08-13 |
Not clear |
| Sutapa Mukherjee, Luna Samanta, Anita Roy, Shravani Bhanja, Gagan B N Chain. Supplementation of T3 recovers hypothyroid rat liver cells from oxidatively damaged inner mitochondrial membrane leading to apoptosis. BioMed research international. vol 2014. 2015-02-12. PMID:24987693. |
increased oxidative stress predominance in the submitochondrial particles (smp) and altered antioxidant defenses in the mitochondrial matrix fraction correlated with hepatocyte apoptosis. |
2015-02-12 |
2023-08-13 |
rat |
| Teresa Mòdol, Natalia Brice, Marina Ruiz de Galarreta, Antonia García Garzón, María J Iraburu, Juan J Martínez-Irujo, María J López-Zabalz. Fibronectin peptides as potential regulators of hepatic fibrosis through apoptosis of hepatic stellate cells. Journal of cellular physiology. vol 230. issue 3. 2015-02-10. PMID:24976518. |
the turnover of extracellular matrix (ecm) components can generate signals that regulate several cellular functions such as proliferation, differentiation, and apoptosis. |
2015-02-10 |
2023-08-13 |
human |
| Teresa Mòdol, Natalia Brice, Marina Ruiz de Galarreta, Antonia García Garzón, María J Iraburu, Juan J Martínez-Irujo, María J López-Zabalz. Fibronectin peptides as potential regulators of hepatic fibrosis through apoptosis of hepatic stellate cells. Journal of cellular physiology. vol 230. issue 3. 2015-02-10. PMID:24976518. |
therefore, in inflammatory liver diseases, locally accumulated peptides could be also important in regulating hepatic fibrosis by inducing apoptosis of hepatic stellate cells (hsc), the primary cellular source of extracellular matrix components. |
2015-02-10 |
2023-08-13 |
human |
| Dengbing Yao, Meiyuan Li, Dingding Shen, Fei Ding, Shibi Lu, Qin Zhao, Xiaosong G. Gene expression profiling of the rat sciatic nerve in early Wallerian degeneration after injury. Neural regeneration research. vol 7. issue 17. 2015-02-06. PMID:25657657. |
we identified 1 546 differentially-expressed genes and 21 distinct patterns of gene expression in early wallerian degeneration, and an enrichment of genes associated with the immune response, acute inflammation, apoptosis, cell adhesion, ion transport and the extracellular matrix. |
2015-02-06 |
2023-08-13 |
rat |
| Nam E Joo, Di Miao, Mercedes Bermúdez, William B Stallcup, Yvonne L Kapil. Shedding of NG2 by MMP-13 attenuates anoikis. DNA and cell biology. vol 33. issue 12. 2015-01-30. PMID:25166220. |
further, since matrix metalloproteinases (mmps) cleave cell surface receptors, play a major role in modulating apoptosis, and are associated with death receptor cleavage during apoptosis, we further hypothesized that cleavage of ng2 could be mediated by mmps to regulate anoikis. |
2015-01-30 |
2023-08-13 |
Not clear |
| Claudio M Mastroianni, Miriam Lichtner, Claudia Mascia, Paola Zuccalà, Vincenzo Vull. Molecular mechanisms of liver fibrosis in HIV/HCV coinfection. International journal of molecular sciences. vol 15. issue 6. 2015-01-29. PMID:24865485. |
the most relevant mechanisms involved include direct viral effects, immune/cytokine dysregulation, altered levels of matrix metalloproteinases and fibrosis biomarkers, increased oxidative stress and hepatocyte apoptosis, hiv-associated gut depletion of cd4 cells, and microbial translocation. |
2015-01-29 |
2023-08-13 |
human |
| Eugene Braunwal. Heart failure. JACC. Heart failure. vol 1. issue 1. 2015-01-27. PMID:24621794. |
these include increased hemodynamic overload, ischemia-related dysfunction, ventricular remodeling, excessive neurohumoral stimulation, abnormal myocyte calcium cycling, excessive or inadequate proliferation of the extracellular matrix, accelerated apoptosis, and genetic mutations. |
2015-01-27 |
2023-08-12 |
Not clear |
| Xuemin Liu, Xufeng Zhang, Junxi Xiang, Yi Lv, Jianhua Sh. miR-451: potential role as tumor suppressor of human hepatoma cell growth and invasion. International journal of oncology. vol 45. issue 2. 2015-01-26. PMID:24841638. |
moreover, mir-451 upregulation abrogated cell invasive ability, accompanied with the decrease of matrix metalloproteinase-9 (mmp-9) expression levels, which may contribute to mir-451-triggered cell apoptosis. |
2015-01-26 |
2023-08-13 |
human |
| Dianne Little, J Will Thompson, Laura G Dubois, David S Ruch, M Arthur Moseley, Farshid Guila. Proteomic differences between male and female anterior cruciate ligament and patellar tendon. PloS one. vol 9. issue 5. 2015-01-23. PMID:24818782. |
important compositional differences between pt and acl were identified, and we identified differences in pathways related to extracellular matrix regulation, complement, apoptosis, metabolism of advanced glycation end-products and response to mechanical loading between males and females. |
2015-01-23 |
2023-08-13 |
Not clear |
| Salvador Gonzalez, Yolanda Gilaberte, Neena Philips, Angeles Juarran. Fernblock, a nutriceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers. International journal of molecular sciences. vol 12. issue 12. 2015-01-22. PMID:22272084. |
its photoprotective effects at a cellular level include a marked decrease of uv-mediated cellular apoptosis and necrosis and a profound inhibition of extracellular matrix remodeling. |
2015-01-22 |
2023-08-12 |
cat |
| Yan Wang, Mark E Lauer, Sanjay Anand, Judith A Mack, Edward V Mayti. Hyaluronan synthase 2 protects skin fibroblasts against apoptosis induced by environmental stress. The Journal of biological chemistry. vol 289. issue 46. 2015-01-20. PMID:25266724. |
we are interested in the role that hyaluronan (ha), an extracellular matrix molecule synthesized by ha synthase enzymes (has), plays in regulating apoptosis in fibroblasts. |
2015-01-20 |
2023-08-13 |
mouse |
| Ganesan Ramamoorthi, Nageswaran Sivalinga. Molecular mechanism of TGF-β signaling pathway in colon carcinogenesis and status of curcumin as chemopreventive strategy. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 8. 2015-01-13. PMID:24668546. |
tgf-β (transforming growth factor-beta) signaling pathway has the potential to regulate various biological processes including cell growth, differentiation, apoptosis, extracellular matrix modeling, and immune response. |
2015-01-13 |
2023-08-12 |
Not clear |
| Akram Ahangarpour, Amin Abdollahzade Fard, Mohammad Kazem Gharibnaseri, Taha Jalali, Iran Rashid. Hydrogen sulfide ameliorates the kidney dysfunction and damage in cisplatin-induced nephrotoxicity in rat. Veterinary research forum : an international quarterly journal. vol 5. issue 2. 2015-01-08. PMID:25568705. |
increases of the proximal tubular cells apoptosis and mesangial matrix in cp nephrotoxicity group rats were observed. |
2015-01-08 |
2023-08-13 |
rat |
| Charmaine Y Pietersen, Sarah A Mauney, Susie S Kim, Maribel P Lim, Robert J Rooney, Jill M Goldstein, Tracey L Petryshen, Larry J Seidman, Martha E Shenton, Robert W McCarley, Kai-C Sonntag, Tsung-Ung W Wo. Molecular profiles of pyramidal neurons in the superior temporal cortex in schizophrenia. Journal of neurogenetics. vol 28. issue 1-2. 2015-01-07. PMID:24702465. |
disturbances of these signaling mechanisms may in part contribute to the altered expression of other genes found to be differentially expressed in this study, such as those that regulate extracellular matrix (ecm), apoptosis, and cytoskeletal and synaptic plasticity. |
2015-01-07 |
2023-08-13 |
human |
| Tian-Biao Zhou, Yuan-Han Qin, Feng-Ying Lei, Wei-Fang Huang, Gregor P C Drumme. Association of prohibitin-1 and 2 with oxidative stress in rats with renal interstitial fibrosis. Molecular biology reports. vol 41. issue 5. 2015-01-05. PMID:24595445. |
phbs, the pro-fibrotic transforming growth factor-β1 (tgf-β1), and the extracellular matrix proteins collagen-iv (col-iv) and fibronectin (fn) were evaluated, as were markers of oxidative stress [total reactive oxygen species (ros), malondialdehyde (mda)] and antioxidative capacity (superoxide dismutase, glutathione), and apoptosis. |
2015-01-05 |
2023-08-12 |
rat |
| Dakuan Gao, Tao Huang, Xiaofan Jiang, Shijie Hu, Lei Zhang, Zhou Fe. Resveratrol protects primary cortical neuron cultures from transient oxygen-glucose deprivation by inhibiting MMP-9. Molecular medicine reports. vol 9. issue 6. 2015-01-05. PMID:24682241. |
the aim of the present study was to further confirm these effects in in vitro primary cortical neuron cultures with transient oxygen-glucose deprivation (ogd), and to investigate whether these effects are due to the inhibition of matrix metalloproteinase-9 (mmp-9) and of cell apoptosis. |
2015-01-05 |
2023-08-12 |
mouse |
| Ning Liu, Wenbo Wang, Zhe Zhao, Tao Zhang, Yuwen Son. Autophagy in human articular chondrocytes is cytoprotective following glucocorticoid stimulation. Molecular medicine reports. vol 9. issue 6. 2015-01-05. PMID:24691715. |
a previous study by our group observed that gc apparently increases the apoptosis of chondrocytes, resulting in the inhibition of extracellular matrix synthesis. |
2015-01-05 |
2023-08-13 |
human |
| Tiziana Nardo, Geraldina Micalizzi, Roberto Vicinanza, Francesca De Iuliis, Ludovica Taglieri, Susanna Scarp. Adhesion to type V collagen enhances staurosporine-induced apoptosis of adrenocortical cancer cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 10. 2015-01-05. PMID:25004807. |
tumor progression is strictly related to the interaction between cancer cells and stroma; yet, extracellular matrix remodeling regulates tumor cell proliferation and apoptosis. |
2015-01-05 |
2023-08-13 |
Not clear |
| Tiziana Nardo, Geraldina Micalizzi, Roberto Vicinanza, Francesca De Iuliis, Ludovica Taglieri, Susanna Scarp. Adhesion to type V collagen enhances staurosporine-induced apoptosis of adrenocortical cancer cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 10. 2015-01-05. PMID:25004807. |
at this purpose, we have studied staurosporine-induced apoptosis of acc cell line h295r adherent to different extracellular matrix molecules. |
2015-01-05 |
2023-08-13 |
Not clear |