| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hongjian Deng, Pengfei Xue, Xiaogang Zhou, Yuntao Wang, Wei Li. CCL4/CCR5 regulates chondrocyte biology and OA progression. Cytokine. vol 183. 2024-09-05. PMID:39236430. |
osteoarthritis (oa) is a common musculoskeletal disorder characterized by chondrocyte apoptosis and extracellular matrix degradation. |
2024-09-05 |
2024-09-08 |
Not clear |
| Juan Liu, Huiyun Wang, Mingyang Lu, Yuan Tian, Tingzhang H. The toxic effect of 2,6-di-tert-butylphenol on embryonic development in zebrafish (Danio rerio): Decreased survival rate, morphological abnormality, and abnormal vascular development. Environmental research. vol 262. issue Pt 1. 2024-08-31. PMID:39214490. |
transcriptome sequencing showed that 2,6-dtbp altered the mrna levels of genes associated with vascular development, oxidative stress, apoptosis, extracellular matrix components and receptors. |
2024-08-31 |
2024-09-04 |
zebrafish |
| Zhiwei Zhang, Bo Li, Shuqin Wu, Yuxin Yang, Binkang Wu, Qi Lai, Fuchong Lai, Fengbo Mo, Yufei Zhong, Song Wang, Runsheng Guo, Bin Zhan. Bergenin protects against osteoarthritis by inhibiting STAT3, NF-κB and Jun pathways and suppressing osteoclastogenesis. Scientific reports. vol 14. issue 1. 2024-08-31. PMID:39217193. |
ber suppressed il-1β-induced chondrocyte apoptosis and extracellular matrix catabolism by inhibiting the stat3, nf-κb and jun signalling pathway in vitro. |
2024-08-31 |
2024-09-04 |
mouse |
| Fahad Marafi, Abdulredha A Esmail, Mahmoud A Alfeeli, Alyaa Sade. 68Ga-Trivehexin PET/CT in Metastatic Non-Small Cell Lung Cancer to the Brain. Clinical nuclear medicine. 2024-08-27. PMID:39190399. |
it plays a role in facilitating invasion, inhibiting apoptosis, regulating expression of matrix metalloproteases, and activating tgf-β in carcinoma. |
2024-08-27 |
2024-08-30 |
Not clear |
| Retraction: Osteogenic protein-1 attenuates apoptosis and enhances matrix synthesis of nucleus pulposus cells under high-magnitude compression though inhibiting the p38 MAPK pathway. Bioscience reports. vol 44. issue 8. 2024-08-22. PMID:39171801. |
retraction: osteogenic protein-1 attenuates apoptosis and enhances matrix synthesis of nucleus pulposus cells under high-magnitude compression though inhibiting the p38 mapk pathway. |
2024-08-22 |
2024-08-24 |
Not clear |
| Retraction: Responses of apoptosis and matrix metabolism of annulus fibrosus cells to different magnitudes of mechanical tension in vitro. Bioscience reports. vol 44. issue 8. 2024-08-22. PMID:39171813. |
retraction: responses of apoptosis and matrix metabolism of annulus fibrosus cells to different magnitudes of mechanical tension in vitro. |
2024-08-22 |
2024-08-24 |
Not clear |
| Ebtesam Al-Suhaimi, Rahaf AlQuwaie, Reem AlSaqabi, Dwi Winarni, Firli Rahmah Primula Dewi, Abdullah A AlRubaish, Adeeb Shehzad, Abdelhamid Elaissar. Hormonal orchestra: mastering mitochondria's role in health and disease. Endocrine. 2024-08-22. PMID:39172335. |
mitochondrial matrix contains chaperones and proteases that regulate intrinsic apoptosis pathway through pro-apoptotic bcl-2 family's proteins bax/bak, and cyt c release, and induces caspase-dependent and independent cells death. |
2024-08-22 |
2024-08-24 |
Not clear |
| Xianling Wang, Yan Yang, Shuang Zhao, Di Wu, Le Li, Zhifeng Zha. Chitosan-based biomaterial delivery strategies for hepatocellular carcinoma. Frontiers in pharmacology. vol 15. 2024-08-20. PMID:39161903. |
chitosan-based biomaterials promote hepatocellular carcinoma apoptosis, exhibit antioxidant and anti-inflammatory effects, inhibit tumor angiogenesis, and improve extracellular matrix remodeling for enhanced anti-tumor therapy. |
2024-08-20 |
2024-08-22 |
Not clear |
| Marek Z Wojtukiewicz, Marta Mysliwiec, Anna Tokajuk, Joanna Kruszewska, Barbara Politynska, Anmbreen Jamroze, Anna M Wojtukiewicz, Dean G Tang, Kenneth V Hon. Tissue factor pathway inhibitor-2 (TFPI-2)-an underappreciated partaker in cancer and metastasis. Cancer metastasis reviews. 2024-08-17. PMID:39153052. |
tfpi-2 interacts with the thrombin cascade and also employs other mechanisms to suppress cancer growth and dissemination, which include extracellular matrix stabilization, promotion of caspase-mediated cell apoptosis, inhibition of angiogenesis and transduction of intracellular signals. |
2024-08-17 |
2024-08-20 |
Not clear |
| Dahe Liu, Yajing Li, Ziwei Bao, Jiaqi He, Yanxing Lan, Zijun Xu, Guoqin Che. Pericardial Delivery of Sodium Alginate-Infusible Extracellular Matrix Composite Hydrogel Promotes Angiogenesis and Intercellular Electrical Conduction after Myocardial Infarction. ACS applied materials & interfaces. 2024-08-15. PMID:39145889. |
this study demonstrates that the sodium alginate/infusible extracellular matrix (sa/iecm) composite hydrogel can effectively prolong the local retention time of iecm in the heart, enhance electrical conduction between cardiomyocytes, promote angiogenesis at ischemic myocardial sites, inhibit apoptosis in the infarcted region, mitigate left ventricular remodeling postmyocardial infarction (mi), and improve cardiac function after infarction. |
2024-08-15 |
2024-08-17 |
Not clear |
| Adriana Vinhas, Márcia T Rodrigues, Ana I Gonçalves, Manuela E Gome. Immunomodulatory Behavior of Tendon Magnetic Cell Sheets can be Modulated in Hypoxic Environments under Magnetic Stimulus. ACS applied materials & interfaces. 2024-08-14. PMID:39143034. |
long lasting inflammatory signals compromise tendon homeostasis and promote tissue degeneration, while tissue oxygen levels affect local cells' responses with hypoxic environments influencing apoptosis, inflammatory mediators, and matrix production. |
2024-08-14 |
2024-08-17 |
human |
| Taha Monadi, Zahra Mohajer, Afsaneh Soltani, Mohammad Amin Khazeei Tabari, Azadeh Manayi, Mohammad Azadbakh. The influence of apigenin on cellular responses to radiation: From protection to sensitization. BioFactors (Oxford, England). 2024-08-12. PMID:39134426. |
it inhibits radiation-induced mammalian target of rapamycin activation, vascular endothelial growth factor (vegf), matrix metalloproteinase-2 (mmp), and stat3 expression, while promoting ampk, autophagy, and apoptosis, suggesting potential in cancer prevention. |
2024-08-12 |
2024-08-16 |
Not clear |
| Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Huajie Li, Panghu Zho. β-Hydroxybutyrate enhances chondrocyte mitophagy and reduces cartilage degeneration in osteoarthritis via the HCAR2/AMPK/PINK1/Parkin pathway. Aging cell. 2024-08-10. PMID:39126207. |
besides, βohb mitigated chondrocyte senescence, inflammatory factors secretion, extracellular matrix degradation, and apoptosis induced by tbhp. |
2024-08-10 |
2024-08-13 |
rat |
| Zhihua Lu, Dandan Wang, Yuzhe Sun, Yan Da. ENO1 regulates IL-1β-induced chondrocyte inflammation, apoptosis and matrix degradation possibly through the potential binding to CRLF1. Tissue & cell. vol 90. 2024-08-08. PMID:39116531. |
eno1 regulates il-1β-induced chondrocyte inflammation, apoptosis and matrix degradation possibly through the potential binding to crlf1. |
2024-08-08 |
2024-08-12 |
human |
| Zhihua Lu, Dandan Wang, Yuzhe Sun, Yan Da. ENO1 regulates IL-1β-induced chondrocyte inflammation, apoptosis and matrix degradation possibly through the potential binding to CRLF1. Tissue & cell. vol 90. 2024-08-08. PMID:39116531. |
silencing eno1 or crlf1 inhibited the il-1β-induced cell viability damage, apoptosis, inflammation, and extracellular matrix degradation. |
2024-08-08 |
2024-08-12 |
human |
| Sarah Snanoudj, Céline Derambure, Cheng Zhang, Nguyen Thi Hai Yen, Céline Lesueur, Sophie Coutant, Lénaïg Abily-Donval, Stéphane Marret, Hong Yang, Adil Mardinoglu, Soumeya Bekri, Abdellah Teban. Genome-wide expression analysis in a Fabry disease human podocyte cell line. Heliyon. vol 10. issue 14. 2024-08-05. PMID:39100494. |
functional analysis of differentially expressed genes showed their involvement in various pathways related to oxidative stress, inflammation, fatty acid metabolism, collagen and extracellular matrix homeostasis, kidney injury, apoptosis, autophagy, and cellular stress response. |
2024-08-05 |
2024-08-07 |
human |
| Yongliang Mei, Liquan Wang, Ting Chen, Chao Song, Kang Cheng, Weiye Cai, Daqian Zhou, Silong Gao, Feng Jiang, Shigui Liu, Zongchao Li. Ferroptosis: A New Direction in the Treatment of Intervertebral Disc Degeneration. Cell biochemistry and biophysics. 2024-08-05. PMID:39102089. |
the current molecular mechanisms of ivdd include extracellular matrix degradation, cellular pyroptosis, apoptosis, necrotic apoptosis, senescence, and the newly discovered ferroptosis [4, 5], among which ferroptosis, as a new hot spot of research, has a non-negligible role in ivdd. |
2024-08-05 |
2024-08-07 |
Not clear |
| Yongliang Mei, Liquan Wang, Ting Chen, Chao Song, Kang Cheng, Weiye Cai, Daqian Zhou, Silong Gao, Feng Jiang, Shigui Liu, Zongchao Li. Ferroptosis: A New Direction in the Treatment of Intervertebral Disc Degeneration. Cell biochemistry and biophysics. 2024-08-05. PMID:39102089. |
our group has previously elucidated the pathogenesis of ivdd in terms of extracellular matrix degradation, myeloid cell senescence and pyroptosis, apoptosis, and inflammatory immunity. |
2024-08-05 |
2024-08-07 |
Not clear |
| Zhongyin Ji, Xiaobin Ren, Jiayan Jin, Xin Ye, Hao Yu, Wenhan Fang, Hui Li, Yihao Zhao, Siyue Tao, Xiangxi Kong, Jiao Cheng, Zhi Shan, Jian Chen, Qingqing Yao, Fengdong Zhao, Junhui Li. Injectable hydrogel encapsulating siMMP13 with anti-ROS and anti-apoptotic functions for osteoarthritis treatment. Journal of nanobiotechnology. vol 22. issue 1. 2024-08-03. PMID:39095867. |
the pathogenesis of oa involves multiple factors, including increased intracellular reactive oxygen species (ros), enhanced chondrocyte apoptosis, and disturbances in cartilage matrix metabolism. |
2024-08-03 |
2024-08-06 |
Not clear |
| Si-Yuan Zhou, Jia-Min Du, Wen-Jing Li, Qi-Yun Liu, Qun-Ye Zhang, Guo-Hai Su, Ying L. The roles and regulatory mechanisms of cigarette smoke constituents in vascular remodeling. International immunopharmacology. vol 140. 2024-07-31. PMID:39083928. |
vascular remodeling is a dynamic process involving cellular and molecular changes, including cell proliferation, migration, apoptosis and extracellular matrix (ecm) synthesis or degradation, which disrupt the homeostasis of endothelial cells (ecs) and vascular smooth muscle cells (vsmcs). |
2024-07-31 |
2024-08-03 |
Not clear |