| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emi Y Tokuda, Jennifer L Leight, Kristi S Anset. Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness. Biomaterials. vol 35. issue 14. 2014-10-29. PMID:24565518. |
the a375 cells were found to be stiffness-independent; matrix elasticity did not alter cell morphology or apoptosis with plx4032 treatment. |
2014-10-29 |
2023-08-12 |
human |
| E V Tchetina, F Mwale, A R Pool. Changes in gene expression associated with matrix turnover, chondrocyte proliferation and hypertrophy in the bovine growth plate. Acta naturae. vol 6. issue 3. 2014-10-28. PMID:25349717. |
this was analyzed by rt-pcr in microsections of the proximal tibial growth plate of bovine fetuses in relationship to expression of genes associated with chondrocyte proliferation, apoptosis, and matrix vascularization. |
2014-10-28 |
2023-08-13 |
cattle |
| E V Tchetina, F Mwale, A R Pool. Changes in gene expression associated with matrix turnover, chondrocyte proliferation and hypertrophy in the bovine growth plate. Acta naturae. vol 6. issue 3. 2014-10-28. PMID:25349717. |
later in the proliferative zone we noted transient expression of proteinases and their inhibitors, extracellular matrix molecules, as well as activity associated with vascularization and apoptosis. |
2014-10-28 |
2023-08-13 |
cattle |
| E V Tchetina, F Mwale, A R Pool. Changes in gene expression associated with matrix turnover, chondrocyte proliferation and hypertrophy in the bovine growth plate. Acta naturae. vol 6. issue 3. 2014-10-28. PMID:25349717. |
with the onset of hypertrophy expression of proteinases and their inhibitors, extracellular matrix molecules, as well as activity associated with vascularization and apoptosis were significantly upregulated. |
2014-10-28 |
2023-08-13 |
cattle |
| E V Tchetina, F Mwale, A R Pool. Changes in gene expression associated with matrix turnover, chondrocyte proliferation and hypertrophy in the bovine growth plate. Acta naturae. vol 6. issue 3. 2014-10-28. PMID:25349717. |
terminal differentiation was characterized by high expression of proteinases and their inhibitors, extracellular matrix molecules, as well as activity associated with apoptosis. |
2014-10-28 |
2023-08-13 |
cattle |
| Mayank Chaturvedi, Leszek Kaczmare. Mmp-9 inhibition: a therapeutic strategy in ischemic stroke. Molecular neurobiology. vol 49. issue 1. 2014-10-27. PMID:24026771. |
in cerebral ischemia there is an enhanced expression of matrix metallo-proteinase-9 (mmp-9), which has been associated with various complications including excitotoxicity, neuronal damage, apoptosis, blood-brain barrier (bbb) opening leading to cerebral edema, and hemorrhagic transformation. |
2014-10-27 |
2023-08-12 |
Not clear |
| Dominik Streyl, Rebecca Kenngott, Nadja Herbach, Rüdiger Wanke, Helmut Blum, Fred Sinowatz, Eckhard Wolf, Holm Zerbe, Stefan Bauersach. Gene expression profiling of bovine peripartal placentomes: detection of molecular pathways potentially involved in the release of foetal membranes. Reproduction (Cambridge, England). vol 143. issue 1. 2014-10-20. PMID:22031715. |
during parturition, a complete shift occurred because the genes with higher mrna levels in ip were nearly all related to three different physiological processes/complexes: i) apoptosis, ii) degradation of extra cellular matrix and iii) innate immune response, which play a fundamental role in placental detachment. |
2014-10-20 |
2023-08-12 |
cattle |
| Dazhi Yang, Daidong Wang, Adam Shimer, Francis H Shen, Xudong Li, Xinlin Yan. Glutathione protects human nucleus pulposus cells from cell apoptosis and inhibition of matrix synthesis. Connective tissue research. vol 55. issue 2. 2014-10-20. PMID:24409809. |
glutathione protects human nucleus pulposus cells from cell apoptosis and inhibition of matrix synthesis. |
2014-10-20 |
2023-08-12 |
human |
| Dazhi Yang, Daidong Wang, Adam Shimer, Francis H Shen, Xudong Li, Xinlin Yan. Glutathione protects human nucleus pulposus cells from cell apoptosis and inhibition of matrix synthesis. Connective tissue research. vol 55. issue 2. 2014-10-20. PMID:24409809. |
abstract cell death (apoptosis and necrosis) and extracellular matrix destruction induced by oxidative stress have been suggested to be closely involved in the process of disc degeneration. |
2014-10-20 |
2023-08-12 |
human |
| Dazhi Yang, Daidong Wang, Adam Shimer, Francis H Shen, Xudong Li, Xinlin Yan. Glutathione protects human nucleus pulposus cells from cell apoptosis and inhibition of matrix synthesis. Connective tissue research. vol 55. issue 2. 2014-10-20. PMID:24409809. |
it was shown that h2o2 dose-dependently promoted nucleus pulposus cell apoptosis detected by terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) staining and decreased mrna levels of matrix proteins aggrecan and type ii collagen determined by quantitative reverse transcription-polymerase chain reaction (rt-pcr). |
2014-10-20 |
2023-08-12 |
human |
| Stian Sjøli, Ann Iren Solli, Oyvind Akselsen, Yang Jiang, Eli Berg, Trond Vidar Hansen, Ingebrigt Sylte, Jan-Olof Winber. PAC-1 and isatin derivatives are weak matrix metalloproteinase inhibitors. Biochimica et biophysica acta. vol 1840. issue 10. 2014-10-17. PMID:25046380. |
matrix metalloproteinases (mmps) have been shown to have a dual role in apoptosis. |
2014-10-17 |
2023-08-13 |
Not clear |
| Lu Liu, Ying Gao, Bin M. Exploring molecular mechanism underlying Chinese medicine syndrome: a study on correlation between Chinese medicine syndrome and biomarkers for ischemic stroke. Chinese journal of integrative medicine. vol 20. issue 1. 2014-10-07. PMID:23529833. |
to investigate whether chinese medicine (cm) syndrome is associated with particular molecular mechanism, we explored the correlation between cm syndrome and changes of intercellular adhesion molecule-1 (icam-1), matrix metalloproteinase 9 (mmp-9) and heat shock protein 70 (hsp70) in patients with ischemic stroke, which were reported to play an important role in the inflammatory and apoptosis cascade. |
2014-10-07 |
2023-08-12 |
Not clear |
| Tomoyuki Muto, Takeshi Kokubu, Yutaka Mifune, Atsuyuki Inui, Yoshifumi Harada, Yoshifumi, Fumiaki Takase, Ryosuke Kuroda, Masahiro Kurosak. Temporary inductions of matrix metalloprotease-3 (MMP-3) expression and cell apoptosis are associated with tendon degeneration or rupture after corticosteroid injection. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 32. issue 10. 2014-10-07. PMID:24985902. |
temporary inductions of matrix metalloprotease-3 (mmp-3) expression and cell apoptosis are associated with tendon degeneration or rupture after corticosteroid injection. |
2014-10-07 |
2023-08-13 |
rat |
| Krzysztof H Włodarski, Ryszard Galus, Aniela Brodzikowska, Paweł K Włodarski, Andrzej Wojtowic. [The importance of lactoferrin in bone regeneration]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 37. issue 217. 2014-10-02. PMID:25154204. |
lactoferrin actives of osteoblast proliferation and bone matrix secretion, and inhibits apoptosis of osteoblast and osteoclastogenesis. |
2014-10-02 |
2023-08-13 |
Not clear |
| Hideyoshi Kawasaki, Tetsuya Yoshida, Kazuhide Horiguchi, Takashi Ohama, Koichi Sat. Characterization of anoikis-resistant cells in mouse colonic epithelium. The Journal of veterinary medical science. vol 75. issue 9. 2014-09-30. PMID:23629020. |
anoikis is a form of apoptosis triggered by inadequate or inappropriate cell matrix contacts. |
2014-09-30 |
2023-08-12 |
mouse |
| Yong Huang, Haijun Yu, Han Lei, Conghua Xie, Yahua Zhon. Matrix metalloproteinase 7 is a useful marker for 5-fluorouracil-based adjuvant chemotherapy in stage II and stage III colorectal cancer patients. Medical oncology (Northwood, London, England). vol 31. issue 3. 2014-09-30. PMID:24469951. |
matrix metalloproteinase 7 (mmp7) was reported to be a negative regulator in fas-mediated apoptosis. |
2014-09-30 |
2023-08-12 |
Not clear |
| Tian-Biao Zhou, Chao Ou, Yuan-Han Qin, Feng-Ying Lei, Wei-Fang Huang, Gregor P C Drumme. LIM homeobox transcription factor 1B expression affects renal interstitial fibrosis and apoptosis in unilateral ureteral obstructed rats. American journal of physiology. Renal physiology. vol 306. issue 12. 2014-09-30. PMID:24785190. |
since no reports were available that studied the link between lmx1b expression and renal interstitial fibrosis, we explored if lmx1b affects typical markers of fibrosis, e.g., extracellular matrix components, profibrotic factors, and apoptosis as the final detrimental consequence. |
2014-09-30 |
2023-08-13 |
rat |
| José M Muñoz-Félix, José M López-Novoa, Carlos Martínez-Salgad. Heterozygous disruption of activin receptor-like kinase 1 is associated with increased renal fibrosis in a mouse model of obstructive nephropathy. Kidney international. vol 85. issue 2. 2014-09-29. PMID:23945497. |
tubulointerstitial fibrosis is characterized by an accumulation of extracellular matrix in the renal interstitium, myofibroblast activation, cell infiltration, and tubular cell apoptosis, leading to chronic renal failure. |
2014-09-29 |
2023-08-12 |
mouse |
| Marco Cardelli, Ralph A Zirngibl, Jonathan F Boetto, Kristen P McKenzie, Tammy-Claire Troy, Kursad Turksen, Jane E Aubi. Cartilage-specific overexpression of ERRγ results in Chondrodysplasia and reduced chondrocyte proliferation. PloS one. vol 8. issue 12. 2014-09-29. PMID:24349082. |
the reduced proliferative zone paralleled a decrease in the number of ki67-positive proliferating cells, with no significant change in apoptosis, and was accompanied by large cell-free swaths of cartilage matrix, which extended through multiple zones of the growth plate. |
2014-09-29 |
2023-08-12 |
mouse |
| Alban Longchamp, Florian Alonso, Céline Dubuis, Florent Allagnat, Xavier Berard, Paolo Meda, François Saucy, Jean-Marc Corpataux, Sébastien Déglise, Jacques-Antoine Haeflige. The use of external mesh reinforcement to reduce intimal hyperplasia and preserve the structure of human saphenous veins. Biomaterials. vol 35. issue 9. 2014-09-26. PMID:24429385. |
in veins submitted to pulsatile high pressure (mean pressure at 100 mmhg) for 3 or 7 days, the use of an external macroporous polyester mesh 1) prevented the dilatation of the vessel, 2) decreased the development of ih, 3) reduced the apoptosis of smooth muscle cells, and the subsequent fibrosis of the media layer, 4) prevented the remodelling of extracellular matrix through the up-regulation of matrix metalloproteinases (mmp-2, mmp-9) and plasminogen activator type i. |
2014-09-26 |
2023-08-12 |
human |