| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naheed Jivraj, Alkystis Phinikaridou, Ajay M Shah, René M Botna. Molecular imaging of myocardial infarction. Basic research in cardiology. vol 109. issue 1. 2014-08-06. PMID:24322905. |
these probes, which target apoptosis, necrosis, neutrophils, monocytes, enzymes, angiogenesis, extracellular matrix, and scar formation have been assessed and validated pre-clinically. |
2014-08-06 |
2023-08-12 |
Not clear |
| Andrew Cho, Naoto Haruyama, Bradford Hall, Mary Jo S Danton, Lu Zhang, Praveen Arany, David J Mooney, Yassine Harichane, Michel Goldberg, Carolyn W Gibson, Ashok B Kulkarn. TGF-ß regulates enamel mineralization and maturation through KLK4 expression. PloS one. vol 8. issue 11. 2014-08-05. PMID:24278477. |
transforming growth factor-ß (tgf-ß) signaling plays an important role in regulating crucial biological processes such as cell proliferation, differentiation, apoptosis, and extracellular matrix remodeling. |
2014-08-05 |
2023-08-12 |
mouse |
| Francesca Tocchioni, Marco Ghionzoli, Laura Calosi, Daniele Guasti, Paolo Romagnoli, Antonio Messine. Rib cartilage characterization in patients affected by pectus excavatum. Anatomical record (Hoboken, N.J. : 2007). vol 296. issue 12. 2014-07-23. PMID:24170345. |
in all cases numerous cells underwent apoptosis accompanied by matrix condensation as shown by electron microscopy. |
2014-07-23 |
2023-08-12 |
human |
| Yuh-Fung Chen, Huei-Yann Tsai, Kuo-Jen Wu, Lian-Ru Siao, W Gibson Woo. Pipoxolan ameliorates cerebral ischemia via inhibition of neuronal apoptosis and intimal hyperplasia through attenuation of VSMC migration and modulation of matrix metalloproteinase-2/9 and Ras/MEK/ERK signaling pathways. PloS one. vol 8. issue 9. 2014-07-14. PMID:24086601. |
pipoxolan ameliorates cerebral ischemia via inhibition of neuronal apoptosis and intimal hyperplasia through attenuation of vsmc migration and modulation of matrix metalloproteinase-2/9 and ras/mek/erk signaling pathways. |
2014-07-14 |
2023-08-12 |
Not clear |
| Fatmagül Kuşku Cabuk, Seyran Yığıt, Lütfiye Demır, Fulya Cakalağaoğlu, Oktay Tarha. Correlation of survivin and MMP9 expressions with prognosis and clinicopathological parameters in surface epithelial ovarian carcinomas. Turk patoloji dergisi. vol 30. issue 1. 2014-07-08. PMID:24448704. |
in our study, we searched the expression of survivin, which prevents apoptosis and matrix metalloproteinase-9 (mmp-9), which promotes the metastasis of the tumour by splitting up the basal membrane in primary epithelial ovarian carcinomas. |
2014-07-08 |
2023-08-12 |
Not clear |
| Anna Bodanovsky, Noga Guttman, Hila Barzilai-Tutsch, Ola Genin, Oshrat Levy, Mark Pines, Orna Halev. Halofuginone improves muscle-cell survival in muscular dystrophies. Biochimica et biophysica acta. vol 1843. issue 7. 2014-06-30. PMID:24703880. |
halofuginone increased apoptosis in α smooth muscle actin- and prolyl 4-hydroxylase β-expressing cells in mdx diaphragm and in myofibroblasts, the major source of extracellular matrix. |
2014-06-30 |
2023-08-13 |
mouse |
| Tomas Kolta. Clusterin: a key player in cancer chemoresistance and its inhibition. OncoTargets and therapy. vol 7. 2014-06-24. PMID:24672247. |
isoform 2 is overexpressed under cellular stress conditions and protects cells from apoptosis by impeding bax actions on the mitochondrial membrane and exerts other protumor activities, like phosphatidylinositol 3-kinase/protein kinase b pathway activation, modulation of extracellular signal-regulated kinase 1/2 signaling and matrix metallopeptidase-9 expression, increased angiogenesis, modulation of the nuclear factor kappa b pathway, among others. |
2014-06-24 |
2023-08-12 |
rat |
| Toshihisa Komor. Mouse models for the evaluation of osteocyte functions. Journal of bone metabolism. vol 21. issue 1. 2014-06-24. PMID:24707467. |
in conditional knockout mice of gap junction protein alpha-1 (gja1), which encodes connexin 43 in gap junction, using dentin matrix protein 1 (dmp1) cre transgenic mice, osteocyte apoptosis and enhanced bone resorption occur, because extracellular communication is intact. |
2014-06-24 |
2023-08-13 |
mouse |
| Helena Kuivaniemi, Evan J Ryer, James R Elmore, Irene Hinterseher, Diane T Smelser, Gerard Trom. Update on abdominal aortic aneurysm research: from clinical to genetic studies. Scientifica. vol 2014. 2014-06-24. PMID:24834361. |
hallmarks of aaa pathogenesis include inflammation, vascular smooth muscle cell apoptosis, extracellular matrix degradation, and oxidative stress. |
2014-06-24 |
2023-08-13 |
Not clear |
| Dong Zhou, Roderick J Tan, Lili Zhou, Yingjian Li, Youhua Li. Kidney tubular β-catenin signaling controls interstitial fibroblast fate via epithelial-mesenchymal communication. Scientific reports. vol 3. 2014-06-23. PMID:23698793. |
tubule-specific knockout of β-catenin diminished renal induction of matrix metalloproteinase (mmp-7), which induced fasl expression in interstitial fibroblasts and potentiated fibroblast apoptosis in vitro. |
2014-06-23 |
2023-08-12 |
mouse |
| Stuart D Horswell, Lee G D Fryer, Claire E Hutchison, Dlear Zindrou, Helen E Speedy, Margaret-M Town, Emma J Duncan, Rasheeta Sivapackianathan, Hetal N Patel, Emma L Jones, Adam Braithwaite, Max P A Salm, Claire K Y Neuwirth, Elizabeth Potter, Jonathan R Anderson, Kenneth M Taylor, Mary Seed, D John Betteridge, Martin A Crook, Anthony S Wierzbicki, James Scott, Rossi P Naoumova, Carol C Shoulder. CDKN2B expression in adipose tissue of familial combined hyperlipidemia patients. Journal of lipid research. vol 54. issue 12. 2014-06-20. PMID:24103848. |
annotation of fchl and control microarray datasets revealed a distinctive fchl transcriptome, characterized by gene expression changes regulating five overlapping systems: the cytoskeleton, cell adhesion and extracellular matrix; vesicular trafficking; lipid homeostasis; and cell cycle and apoptosis. |
2014-06-20 |
2023-08-12 |
human |
| Claudia A Bertuccio, Michael J Capla. Polycystin-1C terminus cleavage and its relation with polycystin-2, two proteins involved in polycystic kidney disease. Medicina. vol 73. issue 2. 2014-06-12. PMID:23570767. |
the cystogenic process is highly complex and involves a high proliferative rate, increased apoptosis, altered protein sorting, changed secretory characteristics, and disorganization of the extracellular matrix. |
2014-06-12 |
2023-08-12 |
Not clear |
| D Sun, Y Zhang, C Wang, X Hua, X A Zhang, J Ya. Sox9-related signaling controls zebrafish juvenile ovary-testis transformation. Cell death & disease. vol 4. 2014-06-12. PMID:24263104. |
these results suggest that high levels of cytoplasmic sox9a and p-erk1/2 activity activate stromal cells and enhance the production of extracellular matrix required for testis cord formation, whereas deregulation and translocation of sox9a and p-erk1/2 induce follicle disassembly and incomplete apoptosis associated with nuclear p53. |
2014-06-12 |
2023-08-12 |
zebrafish |
| V G Dincă, Gh Manol. Organ failure as an expression of organ remodeling. Involvement of oxidative stress. Journal of medicine and life. vol 6. issue 3. 2014-06-10. PMID:24146681. |
the process is complex, including the first functional cell mass reduction (in particular, apoptosis and necrosis), and on the other hand the development of fibrosis process with a starting point at the extracellular matrix. |
2014-06-10 |
2023-08-12 |
Not clear |
| Juan Huang, Han Huang, Min Wu, Jin Li, Hui Xie, Houde Zhou, Eryuan Liao, Yiqun Pen. Connective tissue growth factor induces osteogenic differentiation of vascular smooth muscle cells through ERK signaling. International journal of molecular medicine. vol 32. issue 2. 2014-06-09. PMID:23722620. |
connective tissue growth factor (ctgf) plays an important role in the pathogenesis of atherosclerosis by promoting vascular smooth muscle cell (vsmc) growth, migration, apoptosis, adhesion and the secretion of matrix components. |
2014-06-09 |
2023-08-12 |
mouse |
| Mahalia Chai, Susan P Walker, Clyde Riley, Gregory E Rice, Michael Permezel, Martha Lappa. Effect of supracervical apposition and spontaneous labour on apoptosis and matrix metalloproteinases in human fetal membranes. BioMed research international. vol 2013. 2014-06-03. PMID:24106700. |
effect of supracervical apposition and spontaneous labour on apoptosis and matrix metalloproteinases in human fetal membranes. |
2014-06-03 |
2023-08-12 |
human |
| Mahalia Chai, Susan P Walker, Clyde Riley, Gregory E Rice, Michael Permezel, Martha Lappa. Effect of supracervical apposition and spontaneous labour on apoptosis and matrix metalloproteinases in human fetal membranes. BioMed research international. vol 2013. 2014-06-03. PMID:24106700. |
apoptosis and matrix metalloproteinase (mmp-9) are capable of hydrolysing components of the extracellular matrix and weakening the fetal membranes which leads to eventual rupture, a key process of human parturition. |
2014-06-03 |
2023-08-12 |
human |
| Jaroslava Halper, Michael Kjae. Basic components of connective tissues and extracellular matrix: elastin, fibrillin, fibulins, fibrinogen, fibronectin, laminin, tenascins and thrombospondins. Advances in experimental medicine and biology. vol 802. 2014-05-29. PMID:24443019. |
laminins contribute to the structure of the extracellular matrix (ecm) and modulate cellular functions such as adhesion, differentiation, migration, stability of phenotype, and resistance towards apoptosis. |
2014-05-29 |
2023-08-12 |
Not clear |
| Masahito Shimojo, Yoshie Shudo, Masatoshi Ikeda, Tomoyo Kobashi, Seiji It. The small cell lung cancer-specific isoform of RE1-silencing transcription factor (REST) is regulated by neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100). Molecular cancer research : MCR. vol 11. issue 10. 2014-05-28. PMID:23928058. |
adhesion to the extracellular matrix (ecm) is thought to enhance tumorigenicity and confer resistance to apoptosis. |
2014-05-28 |
2023-08-12 |
Not clear |
| Mohammad Zahid Kamran, Prachi Patil, Kavita Shirsath, Rajiv P Gud. Tyrosine kinase inhibitor AG490 inhibits the proliferation and migration and disrupts actin organization of cancer cells. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 32. issue 4. 2014-05-27. PMID:24579787. |
furthermore, ag490 is seen to induce apoptosis, inhibit cellular migration by disrupting actin organization, and suppress matrix metalloproteinase 2 activity. |
2014-05-27 |
2023-08-12 |
Not clear |