| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eray Kara, Teoman Coşkun, Yavuz Kaya, Okan Yumuş, Seda Vatansever, Ahmet Va. Effects of silymarin and pentoxifylline on matrix metalloproteinase-1 and -2 expression and apoptosis in experimental hepatic fibrosis. Current therapeutic research, clinical and experimental. vol 69. issue 6. 2014-04-02. PMID:24692823. |
effects of silymarin and pentoxifylline on matrix metalloproteinase-1 and -2 expression and apoptosis in experimental hepatic fibrosis. |
2014-04-02 |
2023-08-13 |
Not clear |
| Hua Liang, Han Bing Wang, Hong Zhen Liu, Xian Jie Wen, Qiao Ling Zhou, Cheng Xiang Yan. The effects of combined treatment with sevoflurane and cisplatin on growth and invasion of human adenocarcinoma cell line A549. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 67. issue 6. 2014-03-31. PMID:23639227. |
the expressions of x-linked inhibitor of apoptosis protein (xiap), survivin, matrix metalloproteinase (mmp)-2 and mmp-9 were determined by western blotting. |
2014-03-31 |
2023-08-12 |
human |
| P E Norman, J T Powel. Vitamin D and cardiovascular disease. Circulation research. vol 114. issue 2. 2014-03-28. PMID:24436433. |
the active metabolite of vitamin d, 1α,25-dihydroxyvitamin d, binds to the vitamin d receptor that regulates numerous genes involved in fundamental processes of potential relevance to cardiovascular disease, including cell proliferation and differentiation, apoptosis, oxidative stress, membrane transport, matrix homeostasis, and cell adhesion. |
2014-03-28 |
2023-08-12 |
Not clear |
| Xiao Ma, Jessica Pietsch, Markus Wehland, Herbert Schulz, Katrin Saar, Norbert Hübner, Johann Bauer, Markus Braun, Achim Schwarzwälder, Jürgen Segerer, Maria Birlem, Astrid Horn, Ruth Hemmersbach, Kai Waßer, Jirka Grosse, Manfred Infanger, Daniela Grim. Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 28. issue 2. 2014-03-27. PMID:24196587. |
genes in several biological processes, including apoptosis (n=182), cytoskeleton (n=80), adhesion/extracellular matrix (n=98), proliferation (n=184), stress response (n=268), migration (n=63), angiogenesis (n=39), and signal transduction (n=429), were differentially expressed. |
2014-03-27 |
2023-08-12 |
Not clear |
| Pedro González-Muniesa, María Pilar Marrades, José Alfredo Martínez, María Jesús Moreno-Aliag. Differential proinflammatory and oxidative stress response and vulnerability to metabolic syndrome in habitual high-fat young male consumers putatively predisposed by their genetic background. International journal of molecular sciences. vol 14. issue 9. 2014-03-19. PMID:23975165. |
genes involved in inflammation (alcam, ctsb, c1s, ykl-40, mif, saa2), extracellular matrix remodeling (mmp9, palld), angiogenesis (egfl6, leptin) and oxidative stress (akr1c3, uchl1, hspb7 and nqo1) were upregulated; whereas apoptosis, signal transcription (cited 2 and nr3c1), cell control and cell cycle-related genes were downregulated. |
2014-03-19 |
2023-08-12 |
human |
| Zaitunnatakhin Zamli, Michael A Adams, John F Tarlton, Mohammed Shari. Increased chondrocyte apoptosis is associated with progression of osteoarthritis in spontaneous Guinea pig models of the disease. International journal of molecular sciences. vol 14. issue 9. 2014-03-19. PMID:23994836. |
chondrocyte apoptosis was higher at the later stage of oa development when the cartilage matrix was hypocellular and highly fibrillated, suggesting that chondrocyte apoptosis is a late event in oa. |
2014-03-19 |
2023-08-12 |
Not clear |
| A Maamer-Azzabi, O Ndozangue-Touriguine, J Bréar. Metastatic SW620 colon cancer cells are primed for death when detached and can be sensitized to anoikis by the BH3-mimetic ABT-737. Cell death & disease. vol 4. 2014-03-12. PMID:24030153. |
anoikis, a bax-dependent apoptosis triggered by detachment from the extracellular matrix, is often inhibited in metastatic cancer cells. |
2014-03-12 |
2023-08-12 |
human |
| Panagiota Christia, Nikolaos G Frangogianni. Targeting inflammatory pathways in myocardial infarction. European journal of clinical investigation. vol 43. issue 9. 2014-03-10. PMID:23772948. |
because unrestrained inflammation in the infarcted heart induces matrix degradation and cardiomyocyte apoptosis, timely suppression of the postinfarction inflammatory reaction may be crucial to protect the myocardium from dilative remodelling and progressive dysfunction. |
2014-03-10 |
2023-08-12 |
Not clear |
| Florian Lang, Christos Stournara. Serum and glucocorticoid inducible kinase, metabolic syndrome, inflammation, and tumor growth. Hormones (Athens, Greece). vol 12. issue 2. 2014-03-10. PMID:23933686. |
sgk1 sensitive functions contribute to regulation of epithelial transport, excitability, degranulation, matrix protein deposition, coagulation, platelet aggregation, migration, cell proliferation, and apoptosis. |
2014-03-10 |
2023-08-12 |
mouse |
| M Waheed Roomi, Tatiana Kalinovsky, Nusrath W Roomi, Aleksandra Niedzwiecki, Matthias Rat. Inhibition of the SK-N-MC human neuroblastoma cell line in vivo and in vitro by a novel nutrient mixture. Oncology reports. vol 29. issue 5. 2014-03-05. PMID:23446555. |
we also tested the effect of nm in vitro, evaluating cell viability, secretion of the matrix metalloproteinases (mmp)-2 and mmp-9, tissue inhibitor of metalloproteinase (timp)-2 secretion, matrigel invasion and cellular apoptosis and morphology. |
2014-03-05 |
2023-08-12 |
mouse |
| Danielle Kamato, Micah L Burch, Terrence J Piva, Hossein Babaahmadi Rezaei, Muhamad Ashraf Rostam, Suowen Xu, Wenhua Zheng, Peter J Little, Narin Osma. Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation. Cellular signalling. vol 25. issue 10. 2014-03-03. PMID:23770288. |
transforming growth factor-β (tgf-β) is a secreted homodimeric protein that plays an important role in regulating various cellular responses including cell proliferation and differentiation, extracellular matrix production, embryonic development and apoptosis. |
2014-03-03 |
2023-08-12 |
Not clear |
| Vanessa I Pinto, Vincent W Senini, Yongqiang Wang, Mwayi P Kazembe, Christopher A McCulloc. Filamin A protects cells against force-induced apoptosis by stabilizing talin- and vinculin-containing cell adhesions. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 28. issue 1. 2014-02-26. PMID:24097310. |
we conclude that flna protects against apoptosis in force-loaded cells, and this protection is mediated by enhanced formation and maturation of matrix adhesions. |
2014-02-26 |
2023-08-12 |
Not clear |
| Piedad N De Aza, David García-Bernal, Francesca Cragnolini, Pablo Velasquez, Luis Meseguer-Olm. The effects of Ca2SiO4-Ca3(PO4)2 ceramics on adult human mesenchymal stem cell viability, adhesion, proliferation, differentiation and function. Materials science & engineering. C, Materials for biological applications. vol 33. issue 7. 2014-02-25. PMID:23910308. |
results show a non-cytotoxic effect after applying an indirect apoptosis test (annexin v/7-aad staining), so ahmscs adhered, spread, proliferated and produced extracellular matrix (heparan-sulfate proteoglycan (hs) and osteopontin (op)) on all the ceramics studied. |
2014-02-25 |
2023-08-12 |
human |
| Kanae Ikeda, Toshihiko Torigoe, Yoshitaka Matsumoto, Tatsuya Fujita, Noriyuki Sato, Takatoshi Yotsuyanag. Resveratrol inhibits fibrogenesis and induces apoptosis in keloid fibroblasts. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 21. issue 4. 2014-02-19. PMID:23815229. |
based on this idea, we investigated its effect on the regulation of extracellular matrix expression, proliferation, and apoptosis of keloid fibroblasts. |
2014-02-19 |
2023-08-12 |
Not clear |
| O Blumenfeld, F M K Williams, D J Hart, T D Spector, N Arden, G Livshit. Association between cartilage and bone biomarkers and incidence of radiographic knee osteoarthritis (RKOA) in UK females: a prospective study. Osteoarthritis and cartilage. vol 21. issue 7. 2014-02-18. PMID:23598177. |
the aim of this study was to evaluate the ability of cartilage and bone biomarkers (cartilage oligomeric matrix protein (comp), aggrecan, cellular inhibitor of apoptosis protein (ciap), n-telopeptide-to-helix (ntx)) to predict rkoa incidence in a 10-year follow-up of uk females from the chingford community study. |
2014-02-18 |
2023-08-12 |
Not clear |
| A Mobasheri, M Shakibae. Is tendinitis an inflammatory disease initiated and driven by pro-inflammatory cytokines such as interleukin 1β? Histology and histopathology. vol 28. issue 8. 2014-02-11. PMID:23463583. |
a number of investigators including our group have proposed that pro-inflammatory cytokines such as il-1β are initiators of tendinopathies, stimulating inflammation, apoptosis and extracellular matrix (ecm) degradation. |
2014-02-11 |
2023-08-12 |
Not clear |
| Shaolong Feng, Zhaohui Cao, Xinming Wan. Role of aryl hydrocarbon receptor in cancer. Biochimica et biophysica acta. vol 1836. issue 2. 2014-02-11. PMID:23711559. |
the proposed underlying mechanisms of its actions in cancer involved multiple aspects, (a) inhibiting the functional expression of the key anti-oncogenes (such as p53 and brca1), (b) promoting stem cells transforming and angiogenesis, (c) altering cell survival, proliferation and differentiation by influencing the physiologic processes of cell-cycle, apoptosis, cell contact-inhibition, metabolism and remodel of extracellular matrix, and cell-matrix interaction, (d) cross-talking with the signaling pathways of estrogen receptor and inflammation. |
2014-02-11 |
2023-08-12 |
human |
| Nastaran Alizadeh, Mohammad Mehdi Amiri, Alireza Salek Moghadam, Amir Hassan Zarnani, Farshid Saadat, Farnaz Safavifar, Azar Berahmeh, Mohammad Reza Khorramizade. Effect of toll-like receptor 3 agonists on the functionality and metastatic properties of breast cancer cell model. Iranian journal of allergy, asthma, and immunology. vol 12. issue 2. 2014-02-11. PMID:23754355. |
then, the following assays were performed on the treated cells: dose-response and time-course cytotoxicity using colorimetric method; matrix metalloproteinase-2 (mmp-2) activity using gelatin zymography method; apoptosis using annexin-v flowcytometry method; and relative expression of tlr3 and mmp-2 mrna using reverse transcriptase polymerase chain reaction (rt-pcr) method. |
2014-02-11 |
2023-08-12 |
human |
| Yeong-Hoon Kim, Tae Hee Kim, Sun Woo Kang, Hyun Ju Kim, Seok Ju Park, Kyung Hwan Jeong, Su Kang Kim, Sang Ho Lee, Chun Gyoo Ihm, Tae Won Lee, Ju Young Moon, Young Chul Yoon, Joo-Ho Chun. Association between a TGFBR2 gene polymorphism (rs2228048, Asn389Asn) and acute rejection in Korean kidney transplantation recipients. Immunological investigations. vol 42. issue 4. 2014-02-11. PMID:23883197. |
any quantitative and qualitative changes in tgfbr2 are expected to affect the tgf-β signaling pathway, which occupies a central position with respect to the regulation of cell growth, differentiation, apoptosis, immune reaction, angiogenesis and extracellular matrix formation. |
2014-02-11 |
2023-08-12 |
Not clear |
| Elio Schouppe, Camille Mommer, Kiavash Movahedi, Damya Laoui, Yannick Morias, Conny Gysemans, Ariane Luyckx, Patrick De Baetselier, Jo A Van Ginderachte. Tumor-induced myeloid-derived suppressor cell subsets exert either inhibitory or stimulatory effects on distinct CD8+ T-cell activation events. European journal of immunology. vol 43. issue 11. 2014-02-06. PMID:23878002. |
together, these effects result in an altered cd8(+) t-cell adhesiveness to the extracellular matrix and selectins, sensitivity to fasl-mediated apoptosis, and cytotoxicity. |
2014-02-06 |
2023-08-12 |
Not clear |