| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guo-Ping Shi, Jes S Lindhol. Mast cells in abdominal aortic aneurysms. Current vascular pharmacology. vol 11. issue 3. 2013-12-10. PMID:22724485. |
via multiple activation pathways, mcs release a spectrum of mediators including histamine, inflammatory cytokines, chemokines, growth factors, proteoglycans, and proteases to activate neighboring cells, degrade extracellular matrix proteins, process latent bioactive molecules, promote angiogenesis, recruit additional inflammatory cells, and stimulate vascular cell apoptosis. |
2013-12-10 |
2023-08-12 |
human |
| Won-Dong Kim, Hyun-Sook Chi, Kang-Hyeon Choe, Yeon-Mok Oh, Sang-Do Lee, Kyu-Rae Kim, Kwang-Ha Yoo, David A Ngan, W Mark Elliott, David J Granville, Don D Sin, James C Hog. A possible role for CD8+ and non-CD8+ cell granzyme B in early small airway wall remodelling in centrilobular emphysema. Respirology (Carlton, Vic.). vol 18. issue 4. 2013-12-06. PMID:23421932. |
cd8(+) t cells induce apoptosis by releasing granzymes, which can also cause extracellular matrix degradation and remodelling. |
2013-12-06 |
2023-08-12 |
Not clear |
| Naimeh Rafatian, Denuja Karunakaran, Katey J Rayner, Frans H H Leenen, Ross W Milne, Stewart C Whitma. Cathepsin G deficiency decreases complexity of atherosclerotic lesions in apolipoprotein E-deficient mice. American journal of physiology. Heart and circulatory physiology. vol 305. issue 8. 2013-12-06. PMID:23934850. |
cathepsin g is a serine protease with a broad range of catalytic activities, including production of angiotensin ii, degradation of extracellular matrix and cell-cell junctions, modulation of chemotactic responses, and induction of apoptosis. |
2013-12-06 |
2023-08-12 |
mouse |
| Sahoko Ichihar. The pathological roles of environmental and redox stresses in cardiovascular diseases. Environmental health and preventive medicine. vol 18. issue 3. 2013-11-29. PMID:23275240. |
high levels of oxidative stress resulting from increased cardiac generation of reactive oxygen species (ros) is thought to contribute to contractile and endothelial dysfunction, apoptosis and necrosis of myocytes, and extracellular matrix remodeling in the heart. |
2013-11-29 |
2023-08-12 |
Not clear |
| Margaret E Morrison, Tammy L Palenski, Nasim Jamali, Nader Sheibani, Christine M Sorenso. Modulation of vascular cell function by bim expression. International journal of cell biology. vol 2013. 2013-11-29. PMID:24288535. |
bim is a proapoptotic protein that modulates not only apoptosis but also cellular functions such as migration and extracellular matrix (ecm) protein expression. |
2013-11-29 |
2023-08-12 |
mouse |
| L Speranza, S Franceschelli, M Pesce, A Ferrone, A Patruno, G Riccioni, M A De Lutiis, M Felaco, A Grill. Negative feedback interaction of HO-1/INOS in PBMC of acute congestive heart failure patients. Journal of biological regulators and homeostatic agents. vol 27. issue 3. 2013-11-27. PMID:24152841. |
among the various mechanisms that underlie the pathogenesis of hf, the activation of the immune system leads to a progressive and redundant release of proinflammatory cytokines responsible for a variety of deleterious effects in heart failure, such as endothelial dysfunction, apoptosis of myocytes, activation of mmps (matrix metallo proteinases) and oxidative stress, with the result of decreased inotropism and clinical syndrome such as pulmonary edema,. |
2013-11-27 |
2023-08-12 |
Not clear |
| Haixia Li, Dayong Huang, Zhongxiuzi Gao, Yan Chen, Lina Zhang, Jinhua Zhen. Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and αvβ6 integrin. International journal of oncology. vol 42. issue 5. 2013-11-01. PMID:23546449. |
results showed that scutellarin mediated inhibition of tumor cell proliferation, induced apoptosis, and regulated expression of matrix metallo-proteinase (mmp)-2 and -9, and integrin αvβ6 at the mrna and protein levels in vivo. |
2013-11-01 |
2023-08-12 |
mouse |
| Hong-Xue Shi, Cai Lin, Bei-Bei Lin, Zhou-Guang Wang, Hong-Yu Zhang, Fen-Zan Wu, Yi Cheng, Li-Jun Xiang, Di-Jiong Guo, Xu Luo, Guo-You Zhang, Xiao-Bing Fu, Saverio Bellusci, Xiao-Kun Li, Jian Xia. The anti-scar effects of basic fibroblast growth factor on the wound repair in vitro and in vivo. PloS one. vol 8. issue 4. 2013-10-30. PMID:23565178. |
the levels of fibronectin (fn), tissue inhibitor of metalloproteinase-1 (timp-1) collagen i, and collagen iii were evidently decreased, and matrix metalloproteinase-1 (mmp-1) and apoptosis cells were markedly increased. |
2013-10-30 |
2023-08-12 |
human |
| John Cha, M Waheed Roomi, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rat. Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice. International journal of oncology. vol 42. issue 1. 2013-10-24. PMID:23175106. |
scorbutic tumors demonstrated large dark cores, associated with increased necrotic areas and breaches to the tumor surface, apoptosis and matrix metalloproteinase-9 (mmp-9), and weak, disorganized or missing collagen i tumor capsule. |
2013-10-24 |
2023-08-12 |
mouse |
| Fernanda Faião-Flores, Paulo Rogério Pinto Coelho, João Dias Toledo Arruda-Neto, Silvya Stuchi Maria-Engler, Durvanei Augusto Mari. Cell cycle arrest, extracellular matrix changes and intrinsic apoptosis in human melanoma cells are induced by Boron Neutron Capture Therapy. Toxicology in vitro : an international journal published in association with BIBRA. vol 27. issue 4. 2013-10-22. PMID:23462526. |
cell cycle arrest, extracellular matrix changes and intrinsic apoptosis in human melanoma cells are induced by boron neutron capture therapy. |
2013-10-22 |
2023-08-12 |
human |
| Fernanda Faião-Flores, Paulo Rogério Pinto Coelho, João Dias Toledo Arruda-Neto, Silvya Stuchi Maria-Engler, Durvanei Augusto Mari. Cell cycle arrest, extracellular matrix changes and intrinsic apoptosis in human melanoma cells are induced by Boron Neutron Capture Therapy. Toxicology in vitro : an international journal published in association with BIBRA. vol 27. issue 4. 2013-10-22. PMID:23462526. |
melanoma cells treated with bnct showed significant extracellular matrix (ecm) changes and a significant cyclin d1 decrease, suggesting cell death by necrosis and apoptosis and cell cycle arrest, respectively. |
2013-10-22 |
2023-08-12 |
human |
| Kinga Musiał, Danuta Zwolińsk. New markers of apoptosis in children on chronic dialysis. Apoptosis : an international journal on programmed cell death. vol 18. issue 1. 2013-10-21. PMID:23054081. |
a specific type of apoptosis, anoikis, is connected with the extracellular matrix turnover and cell detachment. |
2013-10-21 |
2023-08-12 |
human |
| Kinga Musiał, Danuta Zwolińsk. New markers of apoptosis in children on chronic dialysis. Apoptosis : an international journal on programmed cell death. vol 18. issue 1. 2013-10-21. PMID:23054081. |
regression analysis revealed that emmprin and mmp-8 predicted various apoptosis markers, whereas e-cadherin turned out the best predictor of both apoptosis (hsp27, sfas, sfasl) and matrix turnover (mmp-7, timp-1, timp-2) indexes in dialyzed patients. |
2013-10-21 |
2023-08-12 |
human |
| T S Zamolodchikov. Serine proteases in immune protection of the small intestine. Biochemistry. Biokhimiia. vol 78. issue 3. 2013-10-17. PMID:23586713. |
proteases of intestinal immunity control the inflammatory response, proliferation of b-lymphocytes, apoptosis, and secretory and contractive activity of the intestine; they release neurogenic factors, inactivate biologically active substances, and are involved in degradation of the intercellular matrix and in tissue remodeling. |
2013-10-17 |
2023-08-12 |
human |
| Yaqian Huang, Jiahong Xia, Jingang Zheng, Bin Geng, Peng Liu, Fang Yu, Bo Liu, Hongquan Zhang, Mingjiang Xu, Ping Ye, Yi Zhu, Qingbo Xu, Xian Wang, Wei Kon. Deficiency of cartilage oligomeric matrix protein causes dilated cardiomyopathy. Basic research in cardiology. vol 108. issue 5. 2013-10-17. PMID:23917519. |
assessment of postnatal comp (-/-) heart at 1 month, although functionally normal, revealed severe cardiac ultrastructure defect, in parallel with cardiomyocyte apoptosis, myofilament loss, connexin-43 deficiency and matrix metalloproteinase activation. |
2013-10-17 |
2023-08-12 |
mouse |
| Enzo Lalli, Mabrouka Doghman, Perle Latre de Late, Abeer El Wakil, Isabelle Mus-Vetea. Beyond steroidogenesis: novel target genes for SF-1 discovered by genomics. Molecular and cellular endocrinology. vol 371. issue 1-2. 2013-09-30. PMID:23168267. |
recent studies using genomic approaches have revealed that sf-1 also has an important role in regulating proliferation of adrenocortical cells and have revealed its role in the control of a variety of biological processes as diverse as angiogenesis, adhesion to the extracellular matrix, cytoskeleton dynamics, transcriptional and post-transcriptional regulation of gene expression and apoptosis in the adrenal cortex. |
2013-09-30 |
2023-08-12 |
Not clear |
| Meng-Yuan Zhu, Ru-Bing Wang, Wen Zhou, Shao-Shun L. [Antitumor effect research progress of shikonin and its derivatives]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 47. issue 5. 2013-09-26. PMID:22812000. |
more emphases are given on the aspects of induction of apoptosis, induction of necrosis, acting on matrix metalloproteinase, acting on the protein tyrosine kinase and antiangiogenesis. |
2013-09-26 |
2023-08-12 |
Not clear |
| Yasumoto Matsui, Atsushi Harad. [Aging of joint]. Clinical calcium. vol 23. issue 1. 2013-09-25. PMID:23268297. |
in oa cartilage, increased degradation and decreased production of major matrix components, like type ii collagen and aggrecan occur, as well as chondrocyte hypertrophy or apoptosis. |
2013-09-25 |
2023-08-12 |
Not clear |
| D Loessner, J A Flegg, H M Byrne, J A Clements, D W Hutmache. Growth of confined cancer spheroids: a combined experimental and mathematical modelling approach. Integrative biology : quantitative biosciences from nano to macro. vol 5. issue 3. 2013-09-24. PMID:23388834. |
immunohistochemistry, imaging and growth analyses were used to quantify the dependence of cell proliferation and apoptosis on matrix stiffness, long-term culture and treatment with the anti-cancer drug paclitaxel. |
2013-09-24 |
2023-08-12 |
human |
| Heather L Grothe, Morgan R Little, Phayvanh P Sjogren, Angela A Chang, Elizabeth F Nelson, Ching Yua. Altered protein conformation and lower stability of the dystrophic transforming growth factor beta-induced protein mutants. Molecular vision. vol 19. 2013-09-24. PMID:23559853. |
transforming growth factor beta-induced protein (tgfbip) is a widely expressed extracellular matrix protein that plays roles in cell adhesion and migration, differentiation, apoptosis, bone morphogenesis, and carcinogenesis. |
2013-09-24 |
2023-08-12 |
Not clear |