| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ya-Fei Zhang, An-Ran Zhang, Bi-Cheng Zhang, Zhi-Guo Rao, Jian-Fei Gao, Mu-Han Lv, Yu-Yun Wu, Su-Min Wang, Rong-Quan Wang, Dian-Chun Fan. MiR-26a regulates cell cycle and anoikis of human esophageal adenocarcinoma cells through Rb1-E2F1 signaling pathway. Molecular biology reports. vol 40. issue 2. 2013-06-17. PMID:23108995. |
resistance to anoikis, the subtype of apoptosis induced by lack of matrix adhesion, contributes to malignant transformation and development of metastasis. |
2013-06-17 |
2023-08-12 |
human |
| Pascal Augustin, Ghada Alsalih, Yoann Launey, Sandrine Delbosc, Liliane Louedec, Véronique Ollivier, Françoise Chau, Philippe Montravers, Xavier Duval, Jean-Baptiste Michel, Olivier Meilha. Predominant role of host proteases in myocardial damage associated with infectious endocarditis induced by Enterococcus faecalis in a rat model. Infection and immunity. vol 81. issue 5. 2013-06-17. PMID:23478315. |
finally, proteolysis of the extracellular matrix and apoptosis were shown to be associated with host proteases. |
2013-06-17 |
2023-08-12 |
rat |
| Sabrina Ruggiero, Raluca Cosgarea, Jan Potempa, Barbara Potempa, Sigrun Eick, Matthias Chique. Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C. Biochimica et biophysica acta. vol 1832. issue 4. 2013-06-13. PMID:23313574. |
gingipains are reported to degrade extracellular matrix (ecm) of periodontal tissues, leading to tissue destruction and apoptosis. |
2013-06-13 |
2023-08-12 |
Not clear |
| Bin Ning, Haifei Liu, Weiming Gong, Jianhao Jiang, Yougu Hu, Shang-You Yan. Biological characteristics of adult degenerative nucleus pulposus cells in a three-dimensional microcarrier stirring culture system. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 31. issue 6. 2013-06-13. PMID:23335154. |
the growth characteristics, proliferation, extracellular matrix secretion, and apoptosis potential were examined to evaluate the different features of the two cultivation methods. |
2013-06-13 |
2023-08-12 |
Not clear |
| Angela L Zachman, Jonathan M Page, Gayathri Prabhakar, Scott A Guelcher, Hak-Joon Sun. Elucidation of adhesion-dependent spontaneous apoptosis in macrophages using phase separated PEG/polyurethane films. Acta biomaterialia. vol 9. issue 2. 2013-06-11. PMID:23128157. |
as both cell-cell and cell-matrix interactions were promoted, hbm apoptosis increased, while their activation as measured by phagocytosis, intracellular reactive oxygen species (ros) level and matrix metalloproteinase-9 production decreased compared to peg-free films. |
2013-06-11 |
2023-08-12 |
human |
| Erin N Howe, Dawn R Cochrane, Diana M Cittelly, Jennifer K Riche. miR-200c targets a NF-κB up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer. PloS one. vol 7. issue 11. 2013-05-30. PMID:23185507. |
anoikis is apoptosis initiated upon cell detachment from the native extracellular matrix. |
2013-05-30 |
2023-08-12 |
Not clear |
| b' Erja Mustonen, Heikki Ruskoaho, Jaana Rys\\xc3\\xa. Thrombospondin-4, tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14: novel extracellular matrix modulating factors in cardiac remodelling. Annals of medicine. vol 44. issue 8. 2013-05-24. PMID:22380695.' |
thrombospondin-4, tumour necrosis factor-like weak inducer of apoptosis (tweak) and its receptor fn14: novel extracellular matrix modulating factors in cardiac remodelling. |
2013-05-24 |
2023-08-12 |
mouse |
| Boban M Erovic, Luke Harris, Mina Jamali, David P Goldstein, Jonathan C Irish, Sylvia L Asa, Ozgur Met. Biomarkers of parathyroid carcinoma. Endocrine pathology. vol 23. issue 4. 2013-05-23. PMID:23001705. |
we constructed a tissue microarray of parathyroid carcinomas from 10 patients as well as parathyroid adenomas from 25 patients and stained the slides for 34 proteins involved in angiogenesis (platelet-derived growth factor receptor (pdgfr)-α, pdgfr-β, vascular endothelial growth factor receptor-2 (vegfr-2), and epidermal growth factor receptor (egfr)), inflammation (cyclooxygenase (cox)-1 and cox-2), cell adhesion (matrix metalloproteinase (mmp)-1, cd9, and keratin 7), cell cycle (cdc2p34, cyclin d1, retinoblastoma (rb), p27, p21, parafibromin, bmi-1, 14-3-3σ, and p53), and apoptosis (bcl-2a, mcl-1, bcl-xl, and glutathione-s-transferase-isoenzyme π (gst-π)) along with some markers of the sonic hedgehog (smo, shh, gli-1, gli-2, gli-3, and patched), mtor (akt, mammalian target of rapamycin (mtor), and forkhead box o (foxo)-1), and wnt (wisp-1, wisp-2, and β-catenin) signal transduction pathways. |
2013-05-23 |
2023-08-12 |
Not clear |
| Marcin Dobaczewski, Judith J de Haan, Nikolaos G Frangogianni. The extracellular matrix modulates fibroblast phenotype and function in the infarcted myocardium. Journal of cardiovascular translational research. vol 5. issue 6. 2013-05-21. PMID:22956156. |
as the scar matures, matrix cross-linking, clearance of matricellular proteins, and reduced growth factor signaling cause deactivation and apoptosis of reparative infarct fibroblasts. |
2013-05-21 |
2023-08-12 |
Not clear |
| Yu Wen Song, Tao Zhang, Wen Bo Wan. Gluococorticoid could influence extracellular matrix synthesis through Sox9 via p38 MAPK pathway. Rheumatology international. vol 32. issue 11. 2013-05-17. PMID:21898067. |
the glucocorticoid-induced p38 inactivation was one mechanism that may response for the inhibition of extracellular matrix synthesis, and these influences appeared earlier than the apoptosis effect. |
2013-05-17 |
2023-08-12 |
human |
| Lei Tian, Li-Sheng He, Bhavesh Soni, Hong-Tao Shan. Myofibroblasts and their resistance to apoptosis: a possible mechanism of osteoradionecrosis. Clinical, cosmetic and investigational dentistry. vol 4. 2013-05-16. PMID:23674922. |
during this process, myofibroblasts may be protected from apoptosis by acquiring an immune-privileged capacity, which allows continuous matrix synthesis. |
2013-05-16 |
2023-08-12 |
Not clear |
| b' Gabriela Moj\\xc5\\xbei\\xc5\\xa1ov\\xc3\\xa1, J\\xc3\\xa1n Moj\\xc5\\xbei\\xc5\\xa1, Martina Pil\\xc3\\xa1tov\\xc3\\xa1, Lenka Varinsk\\xc3\\xa1, Lenka Ivanov\\xc3\\xa1, Ladislav Strojn\\xc3\\xbd, J\\xc3\\xa1n Richnavsk\\xc3\\xb. Antiproliferative and antiangiogenic properties of horse chestnut extract. Phytotherapy research : PTR. vol 27. issue 2. 2013-05-13. PMID:22451355.' |
apoptosis was also further confirmed by dna fragmentation analysis.furthermore, hce inhibited migration of human umbilical vein endothelial cells as well as decreased secretion of matrix metalloproteinase and vascular endothelial growth factor.in conclusion, the present study has assessed the in vitro antiproliferative/antiangiogenic potential of hce. |
2013-05-13 |
2023-08-12 |
human |
| Yong Zhou, Xiangwei Huang, Louise Hecker, Deepali Kurundkar, Ashish Kurundkar, Hui Liu, Tong-Huan Jin, Leena Desai, Karen Bernard, Victor J Thannicka. Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis. The Journal of clinical investigation. vol 123. issue 3. 2013-05-13. PMID:23434591. |
matrix stiffening and myofibroblast resistance to apoptosis are cardinal features of chronic fibrotic diseases involving diverse organ systems. |
2013-05-13 |
2023-08-12 |
mouse |
| Paul R Hiebert, David J Granvill. Granzyme B in injury, inflammation, and repair. Trends in molecular medicine. vol 18. issue 12. 2013-05-06. PMID:23099058. |
although its role in cytotoxic lymphocyte-mediated apoptosis is well established, granzyme b can also degrade extracellular matrix proteins and alter inflammation if present in the extracellular milieu. |
2013-05-06 |
2023-08-12 |
Not clear |
| Lisa Leung, Nikolina Radulovich, Chang-Qi Zhu, Shawna Organ, Bizhan Bandarchi, Melania Pintilie, Christine To, Devang Panchal, Ming Sound Tsa. Lipocalin2 promotes invasion, tumorigenicity and gemcitabine resistance in pancreatic ductal adenocarcinoma. PloS one. vol 7. issue 10. 2013-05-03. PMID:23056397. |
lcn2 has been reported to promote resistance to drug-induced apoptosis, enhance invasion through its physical association with matrix metalloproteinase-9, and promote in vivo tumor growth. |
2013-05-03 |
2023-08-12 |
Not clear |
| Colin Y L Woon, Simon Farnebo, Taliah Schmitt, Armin Kraus, Kai Megerle, Hung Pham, Xinrui Yan, Sanjiv S Gambhir, James Chan. Human flexor tendon tissue engineering: revitalization of biostatic allograft scaffolds. Tissue engineering. Part A. vol 18. issue 23-24. 2013-05-02. PMID:22712522. |
cells reseeded on scored constructs displayed reduced apoptosis, persistent procollagen production, and had a similar ultrastructural relationship to the surrounding matrix as native tenocytes on transmission electron microscopy. |
2013-05-02 |
2023-08-12 |
human |
| Michele Tavecchio, Sofia Lisanti, Aaron Lam, Jagadish C Ghosh, Nina M Martin, Michael O'Connell, Ashani T Weeraratna, Andrew V Kossenkov, Louise C Showe, Dario C Altier. Cyclophilin D extramitochondrial signaling controls cell cycle progression and chemokine-directed cell motility. The Journal of biological chemistry. vol 288. issue 8. 2013-04-25. PMID:23303179. |
here, we show that deletion or reduction in the levels of cyclophilin d (cypd, also called ppif), a mitochondrial matrix peptidyl prolyl isomerase and apoptosis regulator, results in increased cell proliferation and enhanced cell migration and invasion. |
2013-04-25 |
2023-08-12 |
Not clear |
| Takashi Irie, Yuliang Liu, Barbara S Drolet, Elena Carnero, Adolfo García-Sastre, Ronald N Hart. Cytopathogenesis of vesicular stomatitis virus is regulated by the PSAP motif of M protein in a species-dependent manner. Viruses. vol 4. issue 9. 2013-04-24. PMID:23170175. |
the matrix (m) protein of vsv is multifunctional and plays a key role in cytopathogenesis, apoptosis, host protein shut-off, and virion assembly/budding. |
2013-04-24 |
2023-08-12 |
mouse |
| Dulce Maroni, John S Davi. Transforming growth factor Beta 1 stimulates profibrotic activities of luteal fibroblasts in cows. Biology of reproduction. vol 87. issue 5. 2013-04-22. PMID:22811573. |
luteolysis is characterized by angioregression, luteal cell apoptosis, and remodeling of the extracellular matrix characterized by deposition of collagen 1. |
2013-04-22 |
2023-08-12 |
cattle |
| Hisataka Kitano, Atsushi Mamiya, Shinichiro Kokubun, Chiaki Hida. Efficient nonviral gene therapy with FasL and Del1 fragments in mice. The journal of gene medicine. vol 14. issue 11. 2013-04-22. PMID:23136083. |
the present study aimed to improve fasl gene therapy with a nonviral vector by taking advantage of the e3 and c1 domains of del1 protein, which induces apoptosis and localizes to the extracellular matrix. |
2013-04-22 |
2023-08-12 |
mouse |