| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xinfeng Hu, Chen Wang, Yunfeng Ru. [An experimental study on effect of autologous platelet-rich plasma on treatment of early intervertebral disc degeneration]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 26. issue 8. 2013-04-16. PMID:23012935. |
platelet-rich plasma (prp) can stimulate intervertebral disc cell proliferation, promote extracellular matrix synthesis, and inhibit annulus fibrosus cell apoptosis. |
2013-04-16 |
2023-08-12 |
Not clear |
| Aidin Molouki, Khatijah Yusof. NDV-induced apoptosis in absence of Bax; evidence of involvement of apoptotic proteins upstream of mitochondria. Virology journal. vol 9. 2013-04-15. PMID:22935147. |
recently it was shown that following infection of hela cells with newcastle disease virus (ndv), the matrix (m) protein binds to bax and subsequently the intrinsic pathway of apoptosis is activated. |
2013-04-15 |
2023-08-12 |
Not clear |
| Hong Su, Xiao-Yu Si, Wen-Ru Tang, Ying Lu. [The regulation of anoikis in tumor invasion and metastasis]. Yi chuan = Hereditas. vol 35. issue 1. 2013-04-11. PMID:23357260. |
as a barrier to metastasis of cancer, cells that lost contact with the neighbouring cells or extracellular matrix(extracellular matrix, ecm) will be subjected to apoptosis. |
2013-04-11 |
2023-08-12 |
Not clear |
| A Gambelunghe, C Antognelli, N Murgia, M dell'Omo, V N Talesa, G Muz. [Prolonged exposure to crystalline silica Min-U-Sil-5 influences apoptosis or extracellular matrix genes expression in human bronchial epithelial cells]. Giornale italiano di medicina del lavoro ed ergonomia. vol 33. issue 3 Suppl. 2013-04-10. PMID:23393848. |
[prolonged exposure to crystalline silica min-u-sil-5 influences apoptosis or extracellular matrix genes expression in human bronchial epithelial cells]. |
2013-04-10 |
2023-08-12 |
human |
| A Gambelunghe, C Antognelli, N Murgia, M dell'Omo, V N Talesa, G Muz. [Prolonged exposure to crystalline silica Min-U-Sil-5 influences apoptosis or extracellular matrix genes expression in human bronchial epithelial cells]. Giornale italiano di medicina del lavoro ed ergonomia. vol 33. issue 3 Suppl. 2013-04-10. PMID:23393848. |
crystalline silica (min-u-sil-5) induces oxidative stress in human bronchial epithelial cells (beas-2b), through the intracellular accumulation of ros that cause oxidative damage leading to the degradation of extracellular matrix (ecm) proteins and to the loss of cell adhesion molecules inducing apoptosis and genotoxic damage. |
2013-04-10 |
2023-08-12 |
human |
| A Gambelunghe, C Antognelli, N Murgia, M dell'Omo, V N Talesa, G Muz. [Prolonged exposure to crystalline silica Min-U-Sil-5 influences apoptosis or extracellular matrix genes expression in human bronchial epithelial cells]. Giornale italiano di medicina del lavoro ed ergonomia. vol 33. issue 3 Suppl. 2013-04-10. PMID:23393848. |
this paper briefly summarizes some of the recent findings from our laboratories with emphasis on the molecular events by which the cronic and cumulative exposure to crystalline silica can induce cellular damage that promotes changes in extracellular matrix and in apoptosis gene expression. |
2013-04-10 |
2023-08-12 |
human |
| Masoumeh Jahani, Paul G Genever, Ronald J Patton, Fadi Ahwal, Michael J Faga. The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: a computer simulation. Journal of biomechanics. vol 45. issue 16. 2013-04-09. PMID:23040883. |
this work aims to examine the effects of disruption of that intercellular communication by simulation of osteocyte apoptosis in the bone matrix. |
2013-04-09 |
2023-08-12 |
Not clear |
| Inês Falcão-Pires, Adelino F Leite-Moreir. Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment. Heart failure reviews. vol 17. issue 3. 2013-04-05. PMID:21626163. |
left ventricular hypertrophy, metabolic abnormalities, extracellular matrix changes, small vessel disease, cardiac autonomic neuropathy, insulin resistance, oxidative stress, and apoptosis are the most important contributors to diabetic cardiomyopathy onset and progression. |
2013-04-05 |
2023-08-12 |
human |
| Brian Fallica, Joseph S Maffei, Shaun Villa, Guy Makin, Muhammad Zama. Alteration of cellular behavior and response to PI3K pathway inhibition by culture in 3D collagen gels. PloS one. vol 7. issue 10. 2013-04-05. PMID:23110163. |
emerging research has shown that the presence of a three-dimensional (3d) extracellular matrix (ecm) is critical for normal cell behavior including migration, adhesion, signaling, proliferation and apoptosis. |
2013-04-05 |
2023-08-12 |
human |
| N Sharma-Walia, K Patel, K Chandran, A Marginean, V Bottero, N Kerur, A G Pau. COX-2/PGE2: molecular ambassadors of Kaposi's sarcoma-associated herpes virus oncoprotein-v-FLIP. Oncogenesis. vol 1. 2013-04-04. PMID:23552603. |
we demonstrate that cox-2 inhibition, via its chemical inhibitors (ns-398 or celecoxib), reduced v-flip/k13-mediated nf-κb induction, and extracellular matrix (ecm) interaction-mediated signaling, mitochondrial antioxidant enzyme manganese superoxide dismutase (mnsod) levels, and subsequently downregulated detachment-induced apoptosis (anoikis) resistance. |
2013-04-04 |
2023-08-12 |
Not clear |
| Pavel I Nedvetsky, Sang-Ho Kwon, Jayanta Debnath, Keith E Mosto. Cyclic AMP regulates formation of mammary epithelial acini in vitro. Molecular biology of the cell. vol 23. issue 15. 2013-04-03. PMID:22675028. |
in three-dimensional culture utilizing mcf10a mammary epithelial cells, acini form due to integrin-dependent polarization and survival of cells contacting extracellular matrix (ecm), and the apoptosis of inner cells of acini lacking contact with the ecm. |
2013-04-03 |
2023-08-12 |
Not clear |
| Tusty-Jiuan Hsieh, Pei-Chen Hsieh, Yi-Hong Tsai, Chia-Fang Wu, Chia-Chu Liu, Ming-Yen Lin, Ming-Tsang W. Melamine induces human renal proximal tubular cell injury via transforming growth factor-β and oxidative stress. Toxicological sciences : an official journal of the Society of Toxicology. vol 130. issue 1. 2013-03-27. PMID:22915474. |
ckd is a consequence of nephron loss and is associated with the interaction of inflammation, oxidative stress, and transforming growth factor-β (tgf-β), which increases extracellular matrix genes and cell apoptosis with progression to fibrosis and end-stage renal disease. |
2013-03-27 |
2023-08-12 |
human |
| Chloe M McCoy, Dylan Q Nicholas, Kristyn S Master. Sex-related differences in gene expression by porcine aortic valvular interstitial cells. PloS one. vol 7. issue 7. 2013-03-26. PMID:22808080. |
in particular, pathway analysis indicated that cellular proliferation, apoptosis, migration, ossification, angiogenesis, inflammation, and extracellular matrix reorganization were all significantly represented in the data set. |
2013-03-26 |
2023-08-12 |
human |
| Virginie Maire, Fariba Némati, Marion Richardson, Anne Vincent-Salomon, Bruno Tesson, Guillem Rigaill, Eléonore Gravier, Bérengère Marty-Prouvost, Leanne De Koning, Guillaume Lang, David Gentien, Aurélie Dumont, Emmanuel Barillot, Elisabetta Marangoni, Didier Decaudin, Sergio Roman-Roman, Alain Pierré, Francisco Cruzalegui, Stéphane Depil, Gordon C Tucker, Thierry Duboi. Polo-like kinase 1: a potential therapeutic option in combination with conventional chemotherapy for the management of patients with triple-negative breast cancer. Cancer research. vol 73. issue 2. 2013-03-26. PMID:23144294. |
when cells were grown in extracellular matrix gels (matrigel), and exposed to bi-2536, apoptosis was observed specifically in tnbc cancerous cells, and not in a normal cell line. |
2013-03-26 |
2023-08-12 |
Not clear |
| Ravinder Kumar, Davinder Parsad, Amrinderjit J Kanwar, Amrinderjit Kanwar, Deepak Kau. Altered levels of LXR-α: crucial implications in the pathogenesis of vitiligo. Experimental dermatology. vol 21. issue 11. 2013-03-26. PMID:23163651. |
higher expression of lxr-α in perilesional skin melanocytes significantly decreases the adhesion, proliferation and matrix metalloproteinases and increases apoptosis. |
2013-03-26 |
2023-08-12 |
Not clear |
| Joachim C Mertens, Christian D Fingas, John D Christensen, Rory L Smoot, Steven F Bronk, Nathan W Werneburg, Michael P Gustafson, Allan B Dietz, Lewis R Roberts, Alphonse E Sirica, Gregory J Gore. Therapeutic effects of deleting cancer-associated fibroblasts in cholangiocarcinoma. Cancer research. vol 73. issue 2. 2013-03-26. PMID:23221385. |
in a syngeneic rat model of cholangiocarcinoma, navitoclax treatment triggered caf apoptosis, diminishing expression of the desmoplastic extracellular matrix protein tenascin c, suppressing tumor outgrowth, and improving host survival. |
2013-03-26 |
2023-08-12 |
human |
| Xinchun Jin, Jie Liu, Ke J Liu, Gary A Rosenberg, Yi Yang, Wenlan Li. Normobaric hyperoxia combined with minocycline provides greater neuroprotection than either alone in transient focal cerebral ischemia. Experimental neurology. vol 240. 2013-03-25. PMID:23195595. |
normobaric hyperoxia (nbo), which maintains penumbral oxygenation, reduces brain injury during cerebral ischemia, and minocycline, a tetracycline derivative, reduces reperfusion injury, including inflammation, apoptosis and matrix metalloproteinases (mmps) activation. |
2013-03-25 |
2023-08-12 |
rat |
| Walter Manucha, Patricia G Vallé. Apoptosis modulated by oxidative stress and inflammation during obstructive nephropathy. Inflammation & allergy drug targets. vol 11. issue 4. 2013-03-19. PMID:22533548. |
the injured tubular cells linked to interstitial macrophages, and myofibroblasts produce cytokines and growth factors that promote an inflammatory state in the kidney, induce tubular cell apoptosis, and facilitate the accumulation of extracellular matrix. |
2013-03-19 |
2023-08-12 |
Not clear |
| Yi Wang, Guo-Ping Sh. Mast cell chymase and tryptase in abdominal aortic aneurysm formation. Trends in cardiovascular medicine. vol 22. issue 6. 2013-03-19. PMID:22902093. |
mc-specific chymase and tryptase play important roles in inducing endothelial cell expression of adhesion molecules and chemokines to promote leukocyte recruitment, degrading matrix proteins and activating protease-activated receptors to trigger smooth muscle cell apoptosis, and activating other proteases to degrade medial elastin and to enhance angiogenesis. |
2013-03-19 |
2023-08-12 |
human |
| Yasuhiro Hida, Jun-Ichi Hamad. Differential expressions of matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs and their endogenous inhibitors among histologic subtypes of lung cancers. Anti-cancer agents in medicinal chemistry. vol 12. issue 7. 2013-03-14. PMID:22292754. |
matrix metalloproteinases (mmps) and their inhibitors play pleiotropic roles in cancer development, carcinogenesis, apoptosis, angiogenesis, invasion and metastasis. |
2013-03-14 |
2023-08-12 |
Not clear |