| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew M Riopel, Jinming Li, Shangxi Liu, Andrew Leask, Rennian Wan. β1 integrin-extracellular matrix interactions are essential for maintaining exocrine pancreas architecture and function. Laboratory investigation; a journal of technical methods and pathology. vol 93. issue 1. 2013-03-14. PMID:23069938. |
apoptosis was reduced to that of controls when isolated exocrine clusters were cultured in media supplemented with extracellular matrix proteins. |
2013-03-14 |
2023-08-12 |
mouse |
| Giuseppe Distefano, Pietro Sciacc. Molecular pathogenesis of myocardial remodeling and new potential therapeutic targets in chronic heart failure. Italian journal of pediatrics. vol 38. 2013-03-12. PMID:22971785. |
typical features of myocardial remodeling are represented by cardiomyocytes hypertrophy and apoptosis, extracellular matrix alterations, mesenchymal fibrotic and phlogistic processes and by cardiac gene expression modifications with fetal genetic program reactivation. |
2013-03-12 |
2023-08-12 |
Not clear |
| Winson Y Cheung, Rihong Zhai, Penny Bradbury, Jessica Hopkins, Matthew H Kulke, Rebecca S Heist, Kofi Asomaning, Clement Ma, Wei Xu, Zhaoxi Wang, Suzanne Hooshmand, Li Su, David C Christiani, Geoffrey Li. Single nucleotide polymorphisms in the matrix metalloproteinase gene family and the frequency and duration of gastroesophageal reflux disease influence the risk of esophageal adenocarcinoma. International journal of cancer. vol 131. issue 11. 2013-03-08. PMID:22422400. |
the matrix metalloproteinase (mmp) family of proteins mediates various cellular pathways, including apoptosis and angiogenesis. |
2013-03-08 |
2023-08-12 |
Not clear |
| Matthew C Pahl, Kimberly Derr, Gabor Gäbel, Irene Hinterseher, James R Elmore, Charles M Schworer, Thomas C Peeler, David P Franklin, John L Gray, David J Carey, Gerard Tromp, Helena Kuivaniem. MicroRNA expression signature in human abdominal aortic aneurysms. BMC medical genomics. vol 5. 2013-03-05. PMID:22704053. |
histologically aaas are characterized by inflammation, vascular smooth muscle cell apoptosis, and extracellular matrix degradation. |
2013-03-05 |
2023-08-12 |
human |
| Bartley J Gill, Don L Gibbons, Laila C Roudsari, Jennifer E Saik, Zain H Rizvi, Jonathon D Roybal, Jonathan M Kurie, Jennifer L Wes. A synthetic matrix with independently tunable biochemistry and mechanical properties to study epithelial morphogenesis and EMT in a lung adenocarcinoma model. Cancer research. vol 72. issue 22. 2013-03-05. PMID:22952217. |
altering both matrix stiffness and the concentration of cell-adhesive ligand significantly influenced epithelial morphogenesis as manifest by differences in the extent of lumenization, in patterns of intrasphere apoptosis and proliferation, and in expression of epithelial polarity markers. |
2013-03-05 |
2023-08-12 |
Not clear |
| Dong-Xing Cao, Zhi-Jie Li, Xiao-Ou Jiang, Yick Liang Lum, Ester Khin, Nikki P Lee, Guo-Hao Wu, John M Lu. Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers. World journal of gastroenterology. vol 18. issue 30. 2013-03-04. PMID:22912540. |
opn signaling results in various functions, including prevention of apoptosis, modulation of angiogenesis, malfunction of tumor-associated macrophages, degradation of extracellular matrix, activation of phosphoinositide 3-kinase-akt and nuclear factor-κb pathways, which lead to tumor formation and progression, particularly in gastric and liver cancers. |
2013-03-04 |
2023-08-12 |
Not clear |
| Lu Xia, Qing-Lu Luo, Hai-Dan Lin, Jin-Long Zhang, Hua Guo, Cheng-Qi H. The effect of different treatment time of millimeter wave on chondrocyte apoptosis, caspase-3, caspase-8, and MMP-13 expression in rabbit surgically induced model of knee osteoarthritis. Rheumatology international. vol 32. issue 9. 2013-03-01. PMID:21881990. |
the aim of this study is to observe the effect of different treatment time of millimeter wave (mmw) on chondrocyte apoptosis, caspase-3, caspase-8, and matrix metalloproteinase-13 (mmp-13) in rabbit knee osteoarthritis induced by anterior cruciate ligament transection (aclt). |
2013-03-01 |
2023-08-12 |
rabbit |
| Panagiota A Sotiropoulou, Andrea E Karambelas, Maud Debaugnies, Aurelie Candi, Peter Bouwman, Virginie Moers, Tatiana Revenco, Ana Sofia Rocha, Kiyotoshi Sekiguchi, Jos Jonkers, Cedric Blanpai. BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny. Genes & development. vol 27. issue 1. 2013-02-26. PMID:23271346. |
interestingly, hf matrix transient amplifying progenitors present increased dna damage, p53 stabilization, and caspase-dependent apoptosis compared with the interfollicular and sebaceous progenitors, leading to hyperproliferation, apoptosis, and subsequent depletion of the prospective adult hf scs. |
2013-02-26 |
2023-08-12 |
mouse |
| Zun-Ling Li, Shu-Hong Shao, Shu-Yang Xie, Zhen Yue, Ying M. [Anti-sense nucleic acid of CyclinD1 induces apoptosis of lung adenocarcinoma cancer cell A549]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 3. 2013-02-21. PMID:21681345. |
to investigate the mechanism for anti-sense nucleic acid of cyclind1 inducing a549 cells apoptosis, the expression levels of retinoblastoma protein (prb), adenovirus e2 factor-1 (e2f-1), vascular endothelial growth factor (vegf), matrix metalloproteinase (mmp)-2 and mmp-9 were detected by western blot, and the results showed the expressions of these proteins were all decreased significantly in anti-sense nucleic acid of cyclind transfected group, compared with those in negative control and empty vector groups. |
2013-02-21 |
2023-08-12 |
Not clear |
| Hsien-Yi Lin, Liang-Tung Yan. Differential response of epithelial stem cell populations in hair follicles to TGF-β signaling. Developmental biology. vol 373. issue 2. 2013-02-21. PMID:23103542. |
moreover, ablation of tgf-β signaling during anagen leads to increased apoptosis in the secondary hair germ and bulb matrix cells. |
2013-02-21 |
2023-08-12 |
Not clear |
| Daniela Valletta, Barbara Czech, Wolfgang E Thasler, Martina Müller, Anja-Katrin Bosserhoff, Claus Hellerbran. Expression and function of the atypical cadherin FAT1 in chronic liver disease. Biochemical and biophysical research communications. vol 426. issue 3. 2013-02-07. PMID:22959770. |
activation of hepatic stellate cells (hscs) is a key event of hepatic fibrosis since activated hscs are the cellular source of enhanced extracellular matrix deposition, and reversion of liver fibrosis is accompanied by clearance of activated hscs by apoptosis. |
2013-02-07 |
2023-08-12 |
human |
| Dariush Honardoust, Jie Ding, Mathew Varkey, Heather A Shankowsky, Edward E Tredge. Deep dermal fibroblasts refractory to migration and decorin-induced apoptosis contribute to hypertrophic scarring. Journal of burn care & research : official publication of the American Burn Association. vol 33. issue 5. 2013-02-04. PMID:22210076. |
taken together, the findings suggest that reduced migration, lack of decorin, and resistance of deep dermal fibroblasts to decorin-induced apoptosis may result in hypercellularity in injuries involving the deep dermis, leading to deposition of excess extracellular matrix and hts formation. |
2013-02-04 |
2023-08-12 |
Not clear |
| Diao-Zhu Lin, Chuan Yang, Li-Hong Chen, Meng Ren, Ping Zhu, Sheng-Neng Xue, Li Ya. [Effects of matrix metallopeptidase 9 on the proliferation, apoptosis, type I and III procollagen synthesis of rat dermal fibroblasts]. Zhonghua yi xue za zhi. vol 92. issue 8. 2013-01-31. PMID:22490164. |
[effects of matrix metallopeptidase 9 on the proliferation, apoptosis, type i and iii procollagen synthesis of rat dermal fibroblasts]. |
2013-01-31 |
2023-08-12 |
rat |
| Diao-Zhu Lin, Chuan Yang, Li-Hong Chen, Meng Ren, Ping Zhu, Sheng-Neng Xue, Li Ya. [Effects of matrix metallopeptidase 9 on the proliferation, apoptosis, type I and III procollagen synthesis of rat dermal fibroblasts]. Zhonghua yi xue za zhi. vol 92. issue 8. 2013-01-31. PMID:22490164. |
to explore the effects of matrix metallopeptidase 9 (mmp-9) on the proliferation, apoptosis, type i and iii procollagen synthesis of rat dermal fibroblasts. |
2013-01-31 |
2023-08-12 |
rat |
| Xu-Yang Xiao, Xiao-Dong Wang, Dong-Yu Zan. MMP1-1607 1G/2G polymorphism and lung cancer risk: a meta-analysis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 33. issue 6. 2013-01-31. PMID:22965879. |
matrix metalloproteinase-1 (mmp-1) plays an important role in the breakdown of extracellular matrix and mediates pathways of apoptosis, angiogenesis, and immunity. |
2013-01-31 |
2023-08-12 |
Not clear |
| Ji Li, Ting-Xin Jiang, Michael W Hughes, Ping Wu, Juehua Yu, Randall B Widelitz, Guoping Fan, Cheng-Ming Chuon. Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. The Journal of investigative dermatology. vol 132. issue 12. 2013-01-29. PMID:22763785. |
anagen follicles in mutants exhibit decreased proliferation and increased apoptosis in matrix transient-amplifying cells. |
2013-01-29 |
2023-08-12 |
mouse |
| Iris J Edward. Proteoglycans in prostate cancer. Nature reviews. Urology. vol 9. issue 4. 2013-01-28. PMID:22349653. |
through multiple interactions of their core proteins and glycosaminoglycans with extracellular matrix proteins, growth factors and chemokines, proteoglycans affect cell signaling, motility, adhesion, growth and apoptosis. |
2013-01-28 |
2023-08-12 |
Not clear |
| Dan Zhao, Xiu-Fa Tang, Kai Yang, Ji-Yuan Liu, Xiang-Rui M. Over-expression of integrin-linked kinase correlates with aberrant expression of Snail, E-cadherin and N-cadherin in oral squamous cell carcinoma: implications in tumor progression and metastasis. Clinical & experimental metastasis. vol 29. issue 8. 2013-01-28. PMID:22638656. |
integrin-linked kinase (ilk), an intracellular protein with serine/threonine protein kinase activities, plays a key role in integrin mediated cell-excellular matrix interactions, regulating cell proliferation, apoptosis, differentiation, and migration. |
2013-01-28 |
2023-08-12 |
Not clear |
| V Kh Khavinson, N S Lin'kova, V O Polyakova, I M Kvetnoy, V V Benberin, M M D'yakonov, Yu S Titko. Tetrapeptide H-Ala-Glu-Asp-Arg-OH stimulates expression of cytoskeletal and nuclear matrix proteins. Bulletin of experimental biology and medicine. vol 153. issue 4. 2013-01-28. PMID:22977870. |
thus, the previously reported cardioprotective activity of this tetrapeptide is determined by its capacity to activate synthesis of cytoskeletal and nuclear matrix proteins, which stimulates cell proliferation and reduces apoptosis. |
2013-01-28 |
2023-08-12 |
mouse |
| Sokratis Trellakis, Kirsten Bruderek, Claudia A Dumitru, Hossein Gholaman, Xiang Gu, Agnes Bankfalvi, André Scherag, Jan Hütte, Nina Dominas, Götz F Lehnerdt, Thomas K Hoffmann, Stephan Lang, Sven Branda. Polymorphonuclear granulocytes in human head and neck cancer: enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease. International journal of cancer. vol 129. issue 9. 2013-01-24. PMID:21190185. |
in vitro, hnscc-conditioned medium inhibited apoptosis of pmns, increased chemokinesis and chemotaxis of pmns, induced release of lactoferrin and matrix metalloproteinase 9 by pmns and enhanced the secretion of ccl4 by pmn. |
2013-01-24 |
2023-08-12 |
human |