| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ya-Qian Huang, Xian Wang, Wei Kon. [Diabetic cardiomyopathy]. Sheng li ke xue jin zhan [Progress in physiology]. vol 41. issue 1. 2012-10-01. PMID:21417012. |
previous studies have highlighted the importance of metabolic disturbances (dysfunction of glucose transporters, increased free fatty acids, abnormal changes in calcium homeostasis, disordered copper metabolism, insulin resistance), myocardial fibrosis (association with hyperglycemia, myocyte apoptosis, increases in angiotensin ii , igf-1, and pro-inflammatory cytokines, changes in matrix metalloproteinases activity etc. |
2012-10-01 |
2023-08-12 |
Not clear |
| Luciano S A Capettini, Fabrizio Montecucco, Francois Mach, Nikos Stergiopulos, Robson A S Santos, Rafaela F da Silv. Role of renin-angiotensin system in inflammation, immunity and aging. Current pharmaceutical design. vol 18. issue 7. 2012-09-27. PMID:22283774. |
however, some studies suggest an important role of this novel axis in the control of cytokines release as well as cell migration and synthesis, preventing extra-cellular matrix deposition and cell apoptosis. |
2012-09-27 |
2023-08-12 |
Not clear |
| Christian V Recktenwald, Sandra Leisz, André Steven, Kousaku Mimura, Anja Müller, Jens Wulfänger, Rolf Kiessling, Barbara Selige. HER-2/neu-mediated down-regulation of biglycan associated with altered growth properties. The Journal of biological chemistry. vol 287. issue 29. 2012-09-26. PMID:22582394. |
the extracellular matrix protein biglycan (bgn) is a leucine-rich proteoglycan that is involved in the matrix assembly, cellular migration and adhesion, cell growth, and apoptosis. |
2012-09-26 |
2023-08-12 |
human |
| Bulent Satar, Yusuf Hidir, Muhittin A Serdar, Zulkuf Kucuktag, Ali Ugur Ural, Ferit Avcu, Mukerrem Safali, Serpil Oguztuzu. Protein profiling of anastomosed facial nerve treated with mesenchymal stromal cells. Cytotherapy. vol 14. issue 5. 2012-09-25. PMID:22268520. |
our aim was to compare apoptosis scores and the expression of myelin-associated glycoprotein (mag), myelin basic protein (mbp), neural cell adhesion molecule (ncam)-1,matrix metalloproteinase (mmp)-1a, tissue inhibitor of metalloproteinase (timp)-1, timp-1/mmp-1a ratio, nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), ciliary neurotrophic factor (cntf), neurotrophin (nt)-3, nt-4, glial cell-derived neurotropic factor (gdnf), leukemia inhibitory factor (lif), basic fibroblast growth factor (fgf)-2, insulin-like growth factor (igf)-1, platelet-derived growth factor (pdgf)-α and transforming growth factor (tgf)-β1 in anastomosed facial nerves that had been treated with or without msc. |
2012-09-25 |
2023-08-12 |
Not clear |
| E A Kogan, T A Demura, V Ia Vodianoĭ, A V Shurshalin. [Molecular and morphological aspects of endometrial receptivity disorders at chronic endometritis]. Arkhiv patologii. vol 74. issue 3. 2012-09-25. PMID:22937573. |
structure and molecular changes of endometrium at ce include inflammatory infiltration, fibroblastic reactions and alteration of extracellular matrix; apoptosis of functional layer leading to its insusceptibility to the regulatory signals. |
2012-09-25 |
2023-08-12 |
Not clear |
| Annegret Serwe, Kristina Rudolph, Timm Anke, Gerhard Erke. Inhibition of TGF-β signaling, vasculogenic mimicry and proinflammatory gene expression by isoxanthohumol. Investigational new drugs. vol 30. issue 3. 2012-09-20. PMID:21340508. |
tgf-β is a multifunctional cytokine that regulates cell proliferation, differentiation, apoptosis and extracellular matrix production. |
2012-09-20 |
2023-08-12 |
Not clear |
| Igor Pantic, Senka Pantic, Gordana Basta-Jovanovi. Gray level co-occurrence matrix texture analysis of germinal center light zone lymphocyte nuclei: physiology viewpoint with focus on apoptosis. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. vol 18. issue 3. 2012-09-20. PMID:22444139. |
gray level co-occurrence matrix texture analysis of germinal center light zone lymphocyte nuclei: physiology viewpoint with focus on apoptosis. |
2012-09-20 |
2023-08-12 |
Not clear |
| Igor Pantic, Senka Pantic, Gordana Basta-Jovanovi. Gray level co-occurrence matrix texture analysis of germinal center light zone lymphocyte nuclei: physiology viewpoint with focus on apoptosis. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. vol 18. issue 3. 2012-09-20. PMID:22444139. |
in our study we investigated the relationship between conventional morphometric indicators of nuclear size and shape (area and circularity) and the parameters of gray level co-occurrence matrix texture analysis (entropy, homogeneity, and angular second moment) in cells committed to apoptosis. |
2012-09-20 |
2023-08-12 |
Not clear |
| Tatiana Kisseleva, David A Brenne. The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis. Journal of hepatology. vol 56. issue 4. 2012-09-11. PMID:22173163. |
while natural killer (nk) cells are implicated in apoptosis of activated hepatic stellate cells/myofibroblasts, cells of myelo-monocitic lineage secrete matrix metalloproteinases to actively degrade the fibrous scar. |
2012-09-11 |
2023-08-12 |
Not clear |
| Carmen Härdtner, Gabriele Multhoff, Werner Falk, Jürgen Radon. (-)-Epigallocatechin-3-gallate, a green tea-derived catechin, synergizes with celecoxib to inhibit IL-1-induced tumorigenic mediators by human pancreatic adenocarcinoma cells Colo357. European journal of pharmacology. vol 684. issue 1-3. 2012-09-10. PMID:22497997. |
we found that co-incubation of colo357 with celecoxib and egcg synergistically diminished metabolic activity via apoptosis induction and down-regulated release of pro-angiogenic vascular endothelial growth factor (vegf) and invasiveness-promoting matrix metalloproteinase (mmp)-2 to a maximum of 30%. |
2012-09-10 |
2023-08-12 |
human |
| Zhifu Li, Jun Shen, Yuxian Chen, Janying Pan, Hua Zeng, Hang Fang, Zhiqiang Ye, Chun Zeng, Rongkai Zhang, Daozhang Ca. Mitochondrial genome sequencing of chondrocytes in osteoarthritis by human mitochondria RT2 Profiler™ PCR array. Molecular medicine reports. vol 6. issue 1. 2012-09-10. PMID:22504941. |
in oa, mitochondrial-associated signaling has been implicated in the molecular events leading to cartilage degradation, including oxidative stress, defective chondrocyte biosynthesis and growth responses, increased cytokine-induced chondrocyte inflammation and matrix catabolism, cartilage matrix calcification and increased chondrocyte apoptosis. |
2012-09-10 |
2023-08-12 |
human |
| Renu A Kowluru, Qing Zhong, Julia M Santo. Matrix metalloproteinases in diabetic retinopathy: potential role of MMP-9. Expert opinion on investigational drugs. vol 21. issue 6. 2012-09-07. PMID:22519597. |
matrix metalloproteinases (mmps) regulate a variety of cellular functions including apoptosis and angiogenesis. |
2012-09-07 |
2023-08-12 |
Not clear |
| Sonia T Chelbi, Melissa L Wilson, Anne-Clémence Veillard, Sue A Ingles, Jim Zhang, Françoise Mondon, Géraldine Gascoin-Lachambre, Ludivine Doridot, Thérèse-Marie Mignot, Régis Rebourcet, Bruno Carbonne, Jean-Paul Concordet, Sandrine Barbaux, Daniel Vaima. Genetic and epigenetic mechanisms collaborate to control SERPINA3 expression and its association with placental diseases. Human molecular genetics. vol 21. issue 9. 2012-09-06. PMID:22246292. |
overexpression of serpina3 in jeg-3 cells, a trophoblast cell model, decreased cell adhesion to the extracellular matrix and to neighboring cells, but protects them from apoptosis, suggesting a way by which this factor could be deleterious at high doses. |
2012-09-06 |
2023-08-12 |
human |
| Jing Zhang, Gang Zho. Green tea consumption: an alternative approach to managing oral lichen planus. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. vol 61. issue 6. 2012-09-06. PMID:22322481. |
antigen-specific mechanisms in olp consist of antigen presentation, lymphocyte activation, proliferation and migration as well as keratinocyte apoptosis mediated by cd8(+) cytotoxic t-cells, whereas non-specific mechanisms include mast cell degranulation and matrix metalloproteinase (mmp) activation in olp lesions. |
2012-09-06 |
2023-08-12 |
Not clear |
| David Dornbos, Yuchuan Din. Mechanisms of neuronal damage and neuroprotection underlying ischemia/reperfusion injury after physical exercise. Current drug targets. vol 13. issue 2. 2012-09-05. PMID:22204323. |
furthermore, pre-conditioning decreases expression of matrix metalloproteinase (mmp-9) and toll-like receptor-4, which ameliorates the inflammatory response and apoptosis following ischemic insult. |
2012-09-05 |
2023-08-12 |
Not clear |
| Juha P Väyrynen, Juha Vornanen, Taina Tervahartiala, Timo Sorsa, Risto Bloigu, Tuula Salo, Anne Tuomisto, Markus J Mäkine. Serum MMP-8 levels increase in colorectal cancer and correlate with disease course and inflammatory properties of primary tumors. International journal of cancer. vol 131. issue 4. 2012-08-31. PMID:21918979. |
matrix metalloproteinases (mmps) form a family of zinc-dependent endoproteases participating in cancer pathogenesis by promoting invasion and regulating growth signaling, apoptosis, angiogenesis and immune responses. |
2012-08-31 |
2023-08-12 |
Not clear |
| Ping Guo, Su-Zhen Zhang, Hua He, Ying-Ting Zhu, Scheffer C G Tsen. PTX3 controls activation of matrix metalloproteinase 1 and apoptosis in conjunctivochalasis fibroblasts. Investigative ophthalmology & visual science. vol 53. issue 7. 2012-08-31. PMID:22511625. |
ptx3 controls activation of matrix metalloproteinase 1 and apoptosis in conjunctivochalasis fibroblasts. |
2012-08-31 |
2023-08-12 |
Not clear |
| Jack W Penn, Adriaan O Grobbelaar, Kerstin J Rolf. The role of the TGF-β family in wound healing, burns and scarring: a review. International journal of burns and trauma. vol 2. issue 1. 2012-08-30. PMID:22928164. |
other putative mechanisms which may underlie the pathogenesis of hypertrophic scars include excessive inflammation, excessive angiogenesis, altered levels of matrix metalloproteinases, growth factors, and delayed apoptosis of fibrotic myofibroblasts either due to p53 genetic alterations or tensile forces across the wound. |
2012-08-30 |
2023-08-12 |
human |
| I Conejeros, E Jara, M D Carretta, P Alarcón, M A Hidalgo, R A Burgo. 2-Aminoethoxydiphenyl borate (2-APB) reduces respiratory burst, MMP-9 release and CD11b expression, and increases l-selectin shedding in bovine neutrophils. Research in veterinary science. vol 92. issue 1. 2012-08-27. PMID:21071047. |
this study describes the effect of 2-aminoethoxydiphenyl borate (2-apb), a putative store-operated calcium (ca(2+)) entry (soce) inhibitor, on reactive oxygen species (ros) production, matrix metalloproteinase 9 (mmp-9) release, cd11b and l-selectin (cd62l) expression, size changes and apoptosis in bovine neutrophils stimulated with platelet-activating factor (paf). |
2012-08-27 |
2023-08-12 |
cattle |
| Romina Scian, Paula Barrionuevo, Carlos A Fossati, Guillermo H Giambartolomei, M Victoria Delpin. Brucella abortus invasion of osteoblasts inhibits bone formation. Infection and immunity. vol 80. issue 7. 2012-08-24. PMID:22547546. |
in this article, we describe immune mechanisms whereby brucella abortus may invade and replicate within osteoblasts, inducing apoptosis, inhibiting mineral and organic matrix deposition, and inducing upregulation of rankl expression. |
2012-08-24 |
2023-08-12 |
Not clear |